Cytofluorometric assessment of cell cycle progression

Methods in Molecular Biology

Volumn 965, Issue , 2013, Pages 93-120

  Vitale, Ilio ^a,b   Jemaà, Mohamed ^a,b   Galluzzi, Lorenzo ^b,c   Metivier, Didier ^a,b   Castedo, Maria ^a,b   Kroemer, Guido ^a,b,d  

^a Institut Gustave Roussy   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d CENTRE DE RECHERCHE DES CORDELIERS   (France)

Author keywords

Cancer; Cyclin B1; HCT 116; Histone H3; Mitosis

Indexed keywords

CARBANILAMIDE DERIVATIVE; CYCLIN B1; ETHYLENE DIUREA; HISTONE; MICROSPHERE;

ARTICLE; CELL COUNT; CELL CYCLE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN HCT116; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; METABOLISM; METHODOLOGY; PHOSPHORYLATION;

CELL COUNT; CELL CYCLE; CELL PROLIFERATION; CYCLIN B1; FLOW CYTOMETRY; HCT116 CELLS; HISTONES; HUMANS; MICROSPHERES; PHENYLUREA COMPOUNDS; PHOSPHORYLATION; S PHASE;

MLCS; MLOWN;

EID: 84878888306     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-239-1_6     Document Type: Article

References (44)

1. Alberts B (2008) Molecular biology of the cell, extended version, 5th edn. Garland Science, New York
2. Blomen VA, Boonstra J (2007) Cell fate determination during G1 phase progression. Cell Mol Life Sci 64:3084-3104
3. Pfeuty B, David-Pfeuty T, Kaneko K (2008) Underlying principles of cell fate determination during G1 phase of the mammalian cell cycle. Cell Cycle 7:3246-3257
4. Hobert O (2011) Regulation of terminal differentiation programs in the nervous system. Annu Rev Cell Dev Biol 27:681-696
5. Olson EN, Schneider MD (2003) Sizing up the heart: development redux in disease. Genes Dev 17:1937-1956
6. Oh IH, Humphries RK (2012) Concise review: Multidimensional regulation of the hematopoietic stem cell state. Stem Cells 30:82-88
7. Pazolli E, Stewart SA (2008) Senescence: the good the bad and the dysfunctional. Curr Opin Genet Dev 18:42-47
8. Evan GI, d'Adda di Fagagna F (2009) Cellular senescence: hot or what? Curr Opin Genet Dev 19:25-31
9. Morgan DO (2007) The cell cycle: principles of control. New Science Press, London
10. Hochegger H, Takeda S, Hunt T (2008) Cyclin-dependent kinases and cell-cycle transitions: does one fit all? Nat Rev Mol Cell Biol 9:910-916
11. Morgan DO (1997) Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 13:261-291
12. Bloom J, Cross FR (2007) Multiple levels of cyclin specificity in cell-cycle control. Nat Rev Mol Cell Biol 8:149-160
13. Satyanarayana A, Kaldis P (2009) Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene 28:2925-2939
14. Liu X, Winey M (2012) The MPS1 family of protein kinases. Annu Rev Biochem 81: 561-585
15. Malumbres M (2011) Physiological relevance of cell cycle kinases. Physiol Rev 91:973-1007
16. Sancar A, Lindsey-Boltz LA, Unsal-Kacmaz K, Linn S (2004) Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem 73:39-85
17. Foster DA, Yellen P, Xu L, Saqcena M (2010) Regulation of G1 cell cycle progression: distinguishing the restriction point from a nutrientsensing cell growth checkpoint(s). Genes Cancer 1:1124-1131
18. Lindqvist A, Rodriguez-Bravo V, Medema RH (2009) The decision to enter mitosis: feedback and redundancy in the mitotic entry network. J Cell Biol 185:193-202
19. Bartek J, Lukas J (2007) DNA damage checkpoints: from initiation to recovery or adaptation. Curr Opin Cell Biol 19:238-245
20. Gottifredi V, Prives C (2005) The S phase checkpoint: when the crowd meets at the fork. Semin Cell Dev Biol 16:355-368
21. Segurado M, Tercero JA (2009) The S-phase checkpoint: targeting the replication fork. Biol Cell 101:617-627
22. Musacchio A (2011) Spindle assembly checkpoint: the third decade. Philos Trans R Soc Lond B Biol Sci 366:3595-3604
23. Musacchio A, Salmon ED (2007) The spindleassembly checkpoint in space and time. Nat Rev Mol Cell Biol 8:379-393
24. Vitale I, Galluzzi L, Castedo M, Kroemer G (2011) Mitotic catastrophe: a mechanism for avoiding genomic instability. Nat Rev Mol Cell Biol 12:385-392
25. Vitale I, Galluzzi L, Senovilla L, Criollo A, Jemaa M, Castedo M, Kroemer G (2011) Illicit survival of cancer cells during polyploidization and depolyploidization. Cell Death Differ 18:1403-1413
26. Margolis RL, Lohez OD, Andreassen PR (2003) G1 tetraploidy checkpoint and the suppression of tumorigenesis. J Cell Biochem 88:673-683
27. Giacinti C, Giordano A (2006) RB and cell cycle progression. Oncogene 25:5220-5227
28. Giono LE, Manfredi JJ (2006) The p53 tumor suppressor participates in multiple cell cycle checkpoints. J Cell Physiol 209:13-20
29. Deng CX (2006) BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution. Nucleic Acids Res 34: 1416-1426
30. Jiang H, Reinhardt HC, Bartkova J, Tommiska J, Blomqvist C, Nevanlinna H, Bartek J, Yaffe MB, Hemann MT (2009) The combined status of ATM and p53 link tumor development with therapeutic response. Genes Dev 23:1895-1909
31. Stewart ZA, Westfall MD, Pietenpol JA (2003) Cell-cycle dysregulation and anticancer therapy. Trends Pharmacol Sci 24:139-145
32. McDonald ER 3rd, El-Deiry WS (2001) Checkpoint genes in cancer. Ann Med 33: 113-122
33. Vitale I, Senovilla L, Galluzzi L, Criollo A, Vivet S, Castedo M, Kroemer G (2008) Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells. Cell Cycle 7: 1956-1961
34. Vitale I, Galluzzi L, Vivet S, Nanty L, Dessen P, Senovilla L, Olaussen KA, Lazar V, Prudhomme M, Golsteyn RM, Castedo M, Kroemer G (2007) Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway. PLoS One 2:e1337
35. Jemaà M, Vitale I, Kepp O, Berardinelli F, Galluzzi L, Senovilla L, Marino G, Malik SA, Rello-Varona S, Lissa D, Antoccia A, Tailler M, Schlemmer F, Harper F, Pierron G, Castedo M, Kroemer G (2012) Selective killing of p53-deficient cancer cells by SP600125. EMBO Mol Med 4(6):500-514
36. Degenhardt Y, Greshock J, Laquerre S, Gilmartin AG, Jing J, Richter M, Zhang X, Bleam M, Halsey W, Hughes A, Moy C, Liu-Sullivan N, Powers S, Bachman K, Jackson J, Weber B, Wooster R (2010) Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability. Mol Cancer Ther 9:2079-2089
37. Jemaà M, Galluzzi L, Kepp O, Boilève A, Lissa D, Senovilla L, Harper F, Pierron G, Berardinelli F, Antoccia A, Castedo M, Vitale I, Kroemer G (2012) Preferential killing of p53-deficient cancer cells by reversine. Cell Cycle 11(11): 2149-2158
38. Kroemer G, Galluzzi L, Brenner C (2007) Mitochondrial membrane permeabilization in cell death. Physiol Rev 87:99-163
39. Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV, Dawson TM, Dawson VL, El-Deiry WS, Fulda S, Gottlieb E, Green DR, Hengartner MO, Kepp O, Knight RA, Kumar S, Lipton SA, Lu X, Madeo F, Malorni W, Mehlen P, Nunez G, Peter ME, Piacentini M, Rubinsztein DC, Shi Y, Simon HU, Vandenabeele P, White E, Yuan J, Zhivotovsky B, Melino G, Kroemer G (2012) Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 19:107-120
40. Hoffmann J, Vitale I, Buchmann B, Galluzzi L, Schwede W, Senovilla L, Skuballa W, Vivet S, Lichtner RB, Vicencio JM, Panaretakis T, Siemeister G, Lage H, Nanty L, Hammer S, Mittelstaedt K, Winsel S, Eschenbrenner J, Castedo M, Demarche C, Klar U, Kroemer G (2008) Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone. Cancer Res 68: 5301-5308
41. Vitale I, Senovilla L, Jemaa M, Michaud M, Galluzzi L, Kepp O, Nanty L, Criollo A, Rello-Varona S, Manic G, Metivier D, Vivet S, Tajeddine N, Joza N, Valent A, Castedo M, Kroemer G (2010) Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos. EMBO J 29:1272-1284
42. Kepp O, Galluzzi L, Lipinski M, Yuan J, Kroemer G (2011) Cell death assays for drug discovery. Nat Rev Drug Discov 10:221-237
43. Tasdemir E, Galluzzi L, Maiuri MC, Criollo A, Vitale I, Hangen E, Modjtahedi N, Kroemer G (2008) Methods for assessing autophagy and autophagic cell death. Methods Mol Biol 445: 29-76
44. Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, Cohen GM, De Laurenzi V, De Maria R, Deshmukh M, Dynlacht BD, El-Deiry WS, Flavell RA, Fulda S, Garrido C, Golstein P, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Jaattela M, Kepp O, Kimchi A, Klionsky DJ, Knight RA, Kornbluth S, Kumar S, Levine B, Lipton SA, Lugli E, Madeo F, Malomi W, Marine JC, Martin SJ, Medema JP, Mehlen P, Melino G, Moll UM, Morselli E, Nagata S, Nicholson DW, Nicotera P, Nunez G, Oren M, Penninger J, Pervaiz S, Peter ME, Piacentini M, Prehn JH, Puthalakath H, Rabinovich GA, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Scorrano L, Simon HU, Steller H, Tschopp J, Tsujimoto Y, Vandenabeele P, Vitale I, Vousden KH, Youle RJ, Yuan J, Zhivotovsky B, Kroemer G (2009) Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ 16:1093-1107