-
1
-
-
77949546659
-
Protein chemical modification on endogenous amino acids
-
Basle E., Joubert N., Pucheault M. Protein chemical modification on endogenous amino acids. Chem Biol 2010, 17:213-227.
-
(2010)
Chem Biol
, vol.17
, pp. 213-227
-
-
Basle, E.1
Joubert, N.2
Pucheault, M.3
-
3
-
-
0037548053
-
Semisynthesis of proteins by expressed protein ligation
-
Muir T.W. Semisynthesis of proteins by expressed protein ligation. Annu Rev Biochem 2003, 72:249-289.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 249-289
-
-
Muir, T.W.1
-
4
-
-
77953643054
-
Adding new chemistries to the genetic code
-
Liu C.C., Schultz P.G. Adding new chemistries to the genetic code. Annu Rev Biochem 2010, 79:413-444.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 413-444
-
-
Liu, C.C.1
Schultz, P.G.2
-
6
-
-
0025129937
-
Structure of ribonuclease H phased at 2Å resolution by mad analysis of the selenomethionyl protein
-
Yang W., Hendrickson W.A., Crouch R.J., Satow Y. Structure of ribonuclease H phased at 2Å resolution by mad analysis of the selenomethionyl protein. Science 1990, 249:1398-1405.
-
(1990)
Science
, vol.249
, pp. 1398-1405
-
-
Yang, W.1
Hendrickson, W.A.2
Crouch, R.J.3
Satow, Y.4
-
7
-
-
0037157082
-
A designed phenylalanyl-tRNA synthetase variant allows efficient in vivo incorporation of aryl ketone functionality into proteins
-
Datta D., Wang P., Carrico I.S., Mayo S.L., Tirrell D.A. A designed phenylalanyl-tRNA synthetase variant allows efficient in vivo incorporation of aryl ketone functionality into proteins. J Am Chem Soc 2002, 124:5652-5653.
-
(2002)
J Am Chem Soc
, vol.124
, pp. 5652-5653
-
-
Datta, D.1
Wang, P.2
Carrico, I.S.3
Mayo, S.L.4
Tirrell, D.A.5
-
9
-
-
72449121780
-
Molecularly defined antibody conjugation through a selenocysteine interface
-
Hofer T., Skeffington L.R., Chapman C.M., Rader C. Molecularly defined antibody conjugation through a selenocysteine interface. Biochemistry 2009, 48:12047-12057.
-
(2009)
Biochemistry
, vol.48
, pp. 12047-12057
-
-
Hofer, T.1
Skeffington, L.R.2
Chapman, C.M.3
Rader, C.4
-
10
-
-
56049106840
-
Multistep engineering of pyrrolysyl-tRNA synthetase to genetically encode N(epsilon)-(o-azidobenzyloxycarbonyl) lysine for site-specific protein modification
-
Yanagisawa T., Ishii R., Fukunaga R., Kobayashi T., Sakamoto K., Yokoyama S. Multistep engineering of pyrrolysyl-tRNA synthetase to genetically encode N(epsilon)-(o-azidobenzyloxycarbonyl) lysine for site-specific protein modification. Chem Biol 2008, 15:1187-1197.
-
(2008)
Chem Biol
, vol.15
, pp. 1187-1197
-
-
Yanagisawa, T.1
Ishii, R.2
Fukunaga, R.3
Kobayashi, T.4
Sakamoto, K.5
Yokoyama, S.6
-
11
-
-
0035917812
-
Expanding the genetic code of Escherichia coli
-
Wang L., Brock A., Herberich B., Schultz P.G. Expanding the genetic code of Escherichia coli. Science 2001, 292:498-500.
-
(2001)
Science
, vol.292
, pp. 498-500
-
-
Wang, L.1
Brock, A.2
Herberich, B.3
Schultz, P.G.4
-
12
-
-
7744222751
-
A genetically encoded photocaged amino acid
-
Wu N., Deiters A., Cropp T.A., King D., Schultz P.G. A genetically encoded photocaged amino acid. J Am Chem Soc 2004, 126:14306-14307.
-
(2004)
J Am Chem Soc
, vol.126
, pp. 14306-14307
-
-
Wu, N.1
Deiters, A.2
Cropp, T.A.3
King, D.4
Schultz, P.G.5
-
13
-
-
2942630608
-
Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells
-
Zhang Z.W., Alfonta L., Tian F., Bursulaya B., Uryu S., King D.S., Schultz P.G. Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells. Proc Natl Acad Sci U S A 2004, 101:8882-8887.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8882-8887
-
-
Zhang, Z.W.1
Alfonta, L.2
Tian, F.3
Bursulaya, B.4
Uryu, S.5
King, D.S.6
Schultz, P.G.7
-
14
-
-
2442659130
-
An expanded genetic code with a functional quadruplet codon
-
Anderson J.C., Wu N., Santoro S.W., Lakshman V., King D.S., Schultz P.G. An expanded genetic code with a functional quadruplet codon. Proc Natl Acad Sci U S A 2004, 101:7566-7571.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7566-7571
-
-
Anderson, J.C.1
Wu, N.2
Santoro, S.W.3
Lakshman, V.4
King, D.S.5
Schultz, P.G.6
-
15
-
-
40949099577
-
Genetically encoding N-epsilon-acetyllysine in recombinant proteins
-
Neumann H., Peak-Chew S.Y., Chin J.W. Genetically encoding N-epsilon-acetyllysine in recombinant proteins. Nat Chem Biol 2008, 4:232-234.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 232-234
-
-
Neumann, H.1
Peak-Chew, S.Y.2
Chin, J.W.3
-
16
-
-
84866283617
-
Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli
-
Chatterjee A., Xiao H., Schultz P.G. Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli. Proc Natl Acad Sci U S A 2012, 109:14841-14846.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 14841-14846
-
-
Chatterjee, A.1
Xiao, H.2
Schultz, P.G.3
-
17
-
-
24044543111
-
A network of orthogonal ribosome×mRNA pairs
-
Rackham O., Chin J.W. A network of orthogonal ribosome×mRNA pairs. Nat Chem Biol 2005, 1:159-166.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 159-166
-
-
Rackham, O.1
Chin, J.W.2
-
18
-
-
77949772551
-
Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome
-
Neumann H., Wang K., Davis L., Garcia-Alai M., Chin J.W. Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome. Nature 2010, 464:441-444.
-
(2010)
Nature
, vol.464
, pp. 441-444
-
-
Neumann, H.1
Wang, K.2
Davis, L.3
Garcia-Alai, M.4
Chin, J.W.5
-
19
-
-
80052165817
-
Expanding the genetic code of Escherichia coli with phosphoserine
-
Park H.S., Hohn M.J., Umehara T., Guo L.T., Osborne E.M., Benner J., Noren C.J., Rinehart J., Soll D. Expanding the genetic code of Escherichia coli with phosphoserine. Science 2011, 333:1151-1154.
-
(2011)
Science
, vol.333
, pp. 1151-1154
-
-
Park, H.S.1
Hohn, M.J.2
Umehara, T.3
Guo, L.T.4
Osborne, E.M.5
Benner, J.6
Noren, C.J.7
Rinehart, J.8
Soll, D.9
-
20
-
-
80054854782
-
RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites
-
Johnson D.B., Xu J., Shen Z., Takimoto J.K., Schultz M.D., Schmitz R.J., Xiang Z., Ecker J.R., Briggs S.P., Wang L. RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites. Nat Chem Biol 2011, 7:779-786.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 779-786
-
-
Johnson, D.B.1
Xu, J.2
Shen, Z.3
Takimoto, J.K.4
Schultz, M.D.5
Schmitz, R.J.6
Xiang, Z.7
Ecker, J.R.8
Briggs, S.P.9
Wang, L.10
-
21
-
-
58149099860
-
Rapid oxime and hydrazone ligations with aromatic aldehydes for biomolecular labeling
-
Dirksen A., Dawson P.E. Rapid oxime and hydrazone ligations with aromatic aldehydes for biomolecular labeling. Bioconjugate Chem 2008, 19:2543-2548.
-
(2008)
Bioconjugate Chem
, vol.19
, pp. 2543-2548
-
-
Dirksen, A.1
Dawson, P.E.2
-
22
-
-
77949863611
-
Cu-free click cycloaddition reactions in chemical biology
-
Jewett J.C., Bertozzi C.R. Cu-free click cycloaddition reactions in chemical biology. Chem Soc Rev 2010, 39:1272-1279.
-
(2010)
Chem Soc Rev
, vol.39
, pp. 1272-1279
-
-
Jewett, J.C.1
Bertozzi, C.R.2
-
23
-
-
58149099966
-
Tetrazine-based cycloadditions: application to pretargeted live cell imaging
-
Devaraj N.K., Weissleder R., Hilderbrand S.A. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjugate Chem 2008, 19:2297-2299.
-
(2008)
Bioconjugate Chem
, vol.19
, pp. 2297-2299
-
-
Devaraj, N.K.1
Weissleder, R.2
Hilderbrand, S.A.3
-
24
-
-
52049083084
-
Site-specific incorporation of methyl- and acetyl-lysine analogues into recombinant proteins
-
Guo J., Wang J., Lee J.S., Schultz P.G. Site-specific incorporation of methyl- and acetyl-lysine analogues into recombinant proteins. Angew Chem 2008, 47:6399-6401.
-
(2008)
Angew Chem
, vol.47
, pp. 6399-6401
-
-
Guo, J.1
Wang, J.2
Lee, J.S.3
Schultz, P.G.4
-
25
-
-
75749135318
-
Genetically encoded alkenes in yeast
-
Ai H.W., Shen W., Brustad E., Schultz P.G. Genetically encoded alkenes in yeast. Angew Chem 2010, 49:935-937.
-
(2010)
Angew Chem
, vol.49
, pp. 935-937
-
-
Ai, H.W.1
Shen, W.2
Brustad, E.3
Schultz, P.G.4
-
26
-
-
54249099451
-
A genetically encoded boronate-containing amino acid
-
Brustad E., Bushey M.L., Lee J.W., Groff D., Liu W., Schultz P.G. A genetically encoded boronate-containing amino acid. Angew Chem 2008, 47:8220-8223.
-
(2008)
Angew Chem
, vol.47
, pp. 8220-8223
-
-
Brustad, E.1
Bushey, M.L.2
Lee, J.W.3
Groff, D.4
Liu, W.5
Schultz, P.G.6
-
27
-
-
77957323280
-
Genetically encoded initiator for polymer growth from proteins
-
Peeler J.C., Woodman B.F., Averick S., Miyake-Stoner S.J., Stokes A.L., Hess K.R., Matyjaszewski K., Mehl R.A. Genetically encoded initiator for polymer growth from proteins. J Am Chem Soc 2010, 132:13575-13577.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 13575-13577
-
-
Peeler, J.C.1
Woodman, B.F.2
Averick, S.3
Miyake-Stoner, S.J.4
Stokes, A.L.5
Hess, K.R.6
Matyjaszewski, K.7
Mehl, R.A.8
-
28
-
-
80054760119
-
Rapid chemoselective bioconjugation through oxidative coupling of anilines and aminophenols
-
Behrens C.R., Hooker J.M., Obermeyer A.C., Romanini D.W., Katz E.M., Francis M.B. Rapid chemoselective bioconjugation through oxidative coupling of anilines and aminophenols. J Am Chem Soc 2011, 133:16398-16401.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 16398-16401
-
-
Behrens, C.R.1
Hooker, J.M.2
Obermeyer, A.C.3
Romanini, D.W.4
Katz, E.M.5
Francis, M.B.6
-
29
-
-
79960883438
-
Genetically encoded 1,2-aminothiols facilitate rapid and site-specific protein labeling via a bio-orthogonal cyanobenzothiazole condensation
-
Nguyen D.P., Elliott T., Holt M., Muir T.W., Chin J.W. Genetically encoded 1,2-aminothiols facilitate rapid and site-specific protein labeling via a bio-orthogonal cyanobenzothiazole condensation. J Am Chem Soc 2011, 133:11418-11421.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 11418-11421
-
-
Nguyen, D.P.1
Elliott, T.2
Holt, M.3
Muir, T.W.4
Chin, J.W.5
-
30
-
-
84867527159
-
Genetically encoded cyclopropene directs rapid, photoclick-chemistry-mediated protein labeling in mammalian cells
-
Yu Z., Pan Y., Wang Z., Wang J., Lin Q. Genetically encoded cyclopropene directs rapid, photoclick-chemistry-mediated protein labeling in mammalian cells. Angew Chem 2012, 51:10600-10604.
-
(2012)
Angew Chem
, vol.51
, pp. 10600-10604
-
-
Yu, Z.1
Pan, Y.2
Wang, Z.3
Wang, J.4
Lin, Q.5
-
31
-
-
54749084565
-
Hydrolytic stability of hydrazones and oximes
-
Kalia J., Raines R.T. Hydrolytic stability of hydrazones and oximes. Angew Chem 2008, 47:7523-7526.
-
(2008)
Angew Chem
, vol.47
, pp. 7523-7526
-
-
Kalia, J.1
Raines, R.T.2
-
32
-
-
0037422608
-
Addition of the keto functional group to the genetic code of Escherichia coli
-
Wang L., Zhang Z., Brock A., Schultz P.G. Addition of the keto functional group to the genetic code of Escherichia coli. Proc Natl Acad Sci U S A 2003, 100:56-61.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 56-61
-
-
Wang, L.1
Zhang, Z.2
Brock, A.3
Schultz, P.G.4
-
33
-
-
0000096835
-
Click chemistry: diverse chemical function from a few good reactions
-
Kolb H.C., Finn M.G., Sharpless K.B. Click chemistry: diverse chemical function from a few good reactions. Angew Chem 2001, 40:2004-2021.
-
(2001)
Angew Chem
, vol.40
, pp. 2004-2021
-
-
Kolb, H.C.1
Finn, M.G.2
Sharpless, K.B.3
-
34
-
-
84863443015
-
Genetic encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions
-
Lang K., Davis L., Wallace S., Mahesh M., Cox D.J., Blackman M.L., Fox J.M., Chin J.W. Genetic encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions. J Am Chem Soc 2012, 134:10317-10320.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 10317-10320
-
-
Lang, K.1
Davis, L.2
Wallace, S.3
Mahesh, M.4
Cox, D.J.5
Blackman, M.L.6
Fox, J.M.7
Chin, J.W.8
-
35
-
-
79954568227
-
Genetically encoded copper-free click chemistry
-
Plass T., Milles S., Koehler C., Schultz C., Lemke E.A. Genetically encoded copper-free click chemistry. Angew Chem 2011, 50:3878-3881.
-
(2011)
Angew Chem
, vol.50
, pp. 3878-3881
-
-
Plass, T.1
Milles, S.2
Koehler, C.3
Schultz, C.4
Lemke, E.A.5
-
36
-
-
53849105464
-
Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity
-
Blackman M.L., Royzen M., Fox J.M. Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity. J Am Chem Soc 2008, 130:13518-13519.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 13518-13519
-
-
Blackman, M.L.1
Royzen, M.2
Fox, J.M.3
-
37
-
-
84856873462
-
Genetically encoded tetrazine amino acid directs rapid site-specific in vivo bioorthogonal ligation with trans-cyclooctenes
-
Seitchik J.L., Peeler J.C., Taylor M.T., Blackman M.L., Rhoads T.W., Cooley R.B., Refakis C., Fox J.M., Mehl R.A. Genetically encoded tetrazine amino acid directs rapid site-specific in vivo bioorthogonal ligation with trans-cyclooctenes. J Am Chem Soc 2012, 134:2898-2901.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 2898-2901
-
-
Seitchik, J.L.1
Peeler, J.C.2
Taylor, M.T.3
Blackman, M.L.4
Rhoads, T.W.5
Cooley, R.B.6
Refakis, C.7
Fox, J.M.8
Mehl, R.A.9
-
38
-
-
84861499522
-
A genetically encoded norbornene amino acid for the mild and selective modification of proteins in a copper-free click reaction
-
Kaya E., Vrabel M., Deiml C., Prill S., Fluxa V.S., Carell T. A genetically encoded norbornene amino acid for the mild and selective modification of proteins in a copper-free click reaction. Angew Chem Int Ed 2012, 51:5277.
-
(2012)
Angew Chem Int Ed
, vol.51
, pp. 5277
-
-
Kaya, E.1
Vrabel, M.2
Deiml, C.3
Prill, S.4
Fluxa, V.S.5
Carell, T.6
-
39
-
-
84857445877
-
Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction
-
Lang K., Davis L., Torres-Kolbus J., Chou C., Deiters A., Chin J.W. Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction. Nat Chem 2012, 4:298-304.
-
(2012)
Nat Chem
, vol.4
, pp. 298-304
-
-
Lang, K.1
Davis, L.2
Torres-Kolbus, J.3
Chou, C.4
Deiters, A.5
Chin, J.W.6
-
40
-
-
79959370195
-
Optimized clinical performance of growth hormone with an expanded genetic code
-
Cho H., Daniel T., Buechler Y.J., Litzinger D.C., Maio Z., Putnam A.M., Kraynov V.S., Sim B.C., Bussell S., Javahishvili T., Kaphle S., et al. Optimized clinical performance of growth hormone with an expanded genetic code. Proc Natl Acad Sci U S A 2011, 108:9060-9065.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9060-9065
-
-
Cho, H.1
Daniel, T.2
Buechler, Y.J.3
Litzinger, D.C.4
Maio, Z.5
Putnam, A.M.6
Kraynov, V.S.7
Sim, B.C.8
Bussell, S.9
Javahishvili, T.10
Kaphle, S.11
-
41
-
-
84863011453
-
FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents
-
Mu J., Pinkstaff J., Li Z., Skidmore L., Li N., Myler H., Dallas-Yang Q., Putnam A.M., Yao J., Bussell S., Wu M., et al. FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents. Diabetes 2012, 61:505-512.
-
(2012)
Diabetes
, vol.61
, pp. 505-512
-
-
Mu, J.1
Pinkstaff, J.2
Li, Z.3
Skidmore, L.4
Li, N.5
Myler, H.6
Dallas-Yang, Q.7
Putnam, A.M.8
Yao, J.9
Bussell, S.10
Wu, M.11
-
42
-
-
31544441685
-
Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity
-
Doronina S.O., Mendelsohn B.A., Bovee T.D., Cerveny C.G., Alley S.C., Meyer D.L., Oflazoglu E., Toki B.E., Sanderson R.J., Zabinski R.F., Wahl A.F., et al. Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity. Bioconjugate Chem 2006, 17:114-124.
-
(2006)
Bioconjugate Chem
, vol.17
, pp. 114-124
-
-
Doronina, S.O.1
Mendelsohn, B.A.2
Bovee, T.D.3
Cerveny, C.G.4
Alley, S.C.5
Meyer, D.L.6
Oflazoglu, E.7
Toki, B.E.8
Sanderson, R.J.9
Zabinski, R.F.10
Wahl, A.F.11
-
43
-
-
0036007596
-
Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia
-
Hamann P.R., Hinman L.M., Hollander I., Beyer C.F., Lindh D., Holcomb R., Hallett W., Tsou H.R., Upeslacis J., Shochat D., Mountain A., et al. Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia. Bioconjugate Chem 2002, 13:47-58.
-
(2002)
Bioconjugate Chem
, vol.13
, pp. 47-58
-
-
Hamann, P.R.1
Hinman, L.M.2
Hollander, I.3
Beyer, C.F.4
Lindh, D.5
Holcomb, R.6
Hallett, W.7
Tsou, H.R.8
Upeslacis, J.9
Shochat, D.10
Mountain, A.11
-
44
-
-
49449087300
-
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
-
Junutula J.R., Raab H., Clark S., Bhakta S., Leipold D.D., Weir S., Chen Y., Simpson M., Tsai S.P., Dennis M.S., Lu Y., et al. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index. Nat Biotechnol 2008, 26:925-932.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 925-932
-
-
Junutula, J.R.1
Raab, H.2
Clark, S.3
Bhakta, S.4
Leipold, D.D.5
Weir, S.6
Chen, Y.7
Simpson, M.8
Tsai, S.P.9
Dennis, M.S.10
Lu, Y.11
-
45
-
-
84863012529
-
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
-
Shen B.Q., Xu K., Liu L., Raab H., Bhakta S., Kenrick M., Parsons-Reponte K.L., Tien J., Yu S.F., Mai E., Li D., et al. Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates. Nat Biotechnol 2012, 30:184-189.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 184-189
-
-
Shen, B.Q.1
Xu, K.2
Liu, L.3
Raab, H.4
Bhakta, S.5
Kenrick, M.6
Parsons-Reponte, K.L.7
Tien, J.8
Yu, S.F.9
Mai, E.10
Li, D.11
-
46
-
-
84867040452
-
Synthesis of site-specific antibody-drug conjugates using unnatural amino acids
-
Axup J.Y., Bajjuri K.M., Ritland M., Hutchins B.M., Kim C.H., Kazane S.A., Halder R., Forsyth J.S., Santidrian A.F., Stafin K., Lu Y., et al. Synthesis of site-specific antibody-drug conjugates using unnatural amino acids. Proc Natl Acad Sci U S A 2012, 109:16101-16106.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 16101-16106
-
-
Axup, J.Y.1
Bajjuri, K.M.2
Ritland, M.3
Hutchins, B.M.4
Kim, C.H.5
Kazane, S.A.6
Halder, R.7
Forsyth, J.S.8
Santidrian, A.F.9
Stafin, K.10
Lu, Y.11
-
47
-
-
67449156132
-
Bispecific t-cell engaging antibodies for cancer therapy
-
Baeuerle P.A., Reinhardt C. Bispecific t-cell engaging antibodies for cancer therapy. Cancer Res 2009, 69:4941-4944.
-
(2009)
Cancer Res
, vol.69
, pp. 4941-4944
-
-
Baeuerle, P.A.1
Reinhardt, C.2
-
48
-
-
79955970356
-
Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma
-
Moore P.A., Zhang W., Rainey G.J., Burke S., Li H., Huang L., Gorlatov S., Veri M.C., Aggarwal S., Yang Y., Shah K., et al. Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma. Blood 2011, 117:4542-4551.
-
(2011)
Blood
, vol.117
, pp. 4542-4551
-
-
Moore, P.A.1
Zhang, W.2
Rainey, G.J.3
Burke, S.4
Li, H.5
Huang, L.6
Gorlatov, S.7
Veri, M.C.8
Aggarwal, S.9
Yang, Y.10
Shah, K.11
-
49
-
-
66249126868
-
The trifunctional antibody ertumaxomab destroys tumor cells that express low levels of human epidermal growth factor receptor 2
-
Jager M., Schoberth A., Ruf P., Hess J., Lindhofer H. The trifunctional antibody ertumaxomab destroys tumor cells that express low levels of human epidermal growth factor receptor 2. Cancer Res 2009, 69:4270-4276.
-
(2009)
Cancer Res
, vol.69
, pp. 4270-4276
-
-
Jager, M.1
Schoberth, A.2
Ruf, P.3
Hess, J.4
Lindhofer, H.5
-
50
-
-
35948977323
-
Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin
-
Wu C., Ying H., Grinnell C., Bryant S., Miller R., Clabbers A., Bose S., McCarthy D., Zhu R.R., Santora L., Davis-Taber R., et al. Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin. Nat Biotechnol 2007, 25:1290-1297.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1290-1297
-
-
Wu, C.1
Ying, H.2
Grinnell, C.3
Bryant, S.4
Miller, R.5
Clabbers, A.6
Bose, S.7
McCarthy, D.8
Zhu, R.R.9
Santora, L.10
Davis-Taber, R.11
-
51
-
-
4644258744
-
Chemical production of bispecific antibodies
-
Graziano R.F., Guptill P. Chemical production of bispecific antibodies. Methods Mol Biol 2004, 283:71-85.
-
(2004)
Methods Mol Biol
, vol.283
, pp. 71-85
-
-
Graziano, R.F.1
Guptill, P.2
-
52
-
-
77951523463
-
Bispecific antibodies for cancer therapy: the light at the end of the tunnel?
-
Chames P., Baty D. Bispecific antibodies for cancer therapy: the light at the end of the tunnel?. mAbs 2009, 1:539-547.
-
(2009)
mAbs
, vol.1
, pp. 539-547
-
-
Chames, P.1
Baty, D.2
-
53
-
-
84862538751
-
Synthesis of bispecific antibodies using genetically encoded unnatural amino acids
-
Kim C.H., Axup J.Y., Dubrovska A., Kazane S.A., Hutchins B.A., Wold E.D., Smider V.V., Schultz P.G. Synthesis of bispecific antibodies using genetically encoded unnatural amino acids. J Am Chem Soc 2012, 134:9918-9921.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 9918-9921
-
-
Kim, C.H.1
Axup, J.Y.2
Dubrovska, A.3
Kazane, S.A.4
Hutchins, B.A.5
Wold, E.D.6
Smider, V.V.7
Schultz, P.G.8
-
54
-
-
84872105713
-
Self-assembled antibody multimers through peptide nucleic acid conjugation
-
Kazane S.A., Axup J.Y., Kim C.H., Ciobanu M., Wold E.D., Barluenga S., Hutchins B.A., Schultz P.G., Winssinger N., Smider V.V. Self-assembled antibody multimers through peptide nucleic acid conjugation. J Am Chem Soc 2013, 135(1):340-346.
-
(2013)
J Am Chem Soc
, vol.135
, Issue.1
, pp. 340-346
-
-
Kazane, S.A.1
Axup, J.Y.2
Kim, C.H.3
Ciobanu, M.4
Wold, E.D.5
Barluenga, S.6
Hutchins, B.A.7
Schultz, P.G.8
Winssinger, N.9
Smider, V.V.10
-
55
-
-
84857979125
-
Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR
-
Kazane S.A., Sok D., Cho E.H., Uson M.L., Kuhn P., Schultz P.G., Smider V.V. Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR. Proc Natl Acad Sci U S A 2012, 109:3731-3736.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 3731-3736
-
-
Kazane, S.A.1
Sok, D.2
Cho, E.H.3
Uson, M.L.4
Kuhn, P.5
Schultz, P.G.6
Smider, V.V.7
-
56
-
-
58849110330
-
A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer
-
Brustad E.M., Lemke E.A., Schultz P.G., Deniz A.A. A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer. J Am Chem Soc 2008, 130:17664-17665.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 17664-17665
-
-
Brustad, E.M.1
Lemke, E.A.2
Schultz, P.G.3
Deniz, A.A.4
-
57
-
-
38349107042
-
Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis
-
Ye S., Köhrer C., Huber T., Kazmi M., Sachdev P., Yan E.C.Y., Bhagat A., RajBhandary U.L., Sakmar T.P. Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. J Biol Chem 2008, 283:1525-1533.
-
(2008)
J Biol Chem
, vol.283
, pp. 1525-1533
-
-
Ye, S.1
Köhrer, C.2
Huber, T.3
Kazmi, M.4
Sachdev, P.5
Yan, E.C.Y.6
Bhagat, A.7
RajBhandary, U.L.8
Sakmar, T.P.9
-
58
-
-
84863443015
-
Genetic encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions
-
Lang K., Davis L., Wallace S., Mahesh M., Cox D.J., Blackman M.L., Fox J.M., Chin J.W. Genetic encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions. J Am Chem Soc 2012, 134:10317-10320.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 10317-10320
-
-
Lang, K.1
Davis, L.2
Wallace, S.3
Mahesh, M.4
Cox, D.J.5
Blackman, M.L.6
Fox, J.M.7
Chin, J.W.8
-
59
-
-
76049105524
-
Site-directed spin labeling of a genetically encoded unnatural amino acid
-
Fleissner M.R., Brustad E.M., Kálai T., Altenbach C., Cascio D., Peters F.B., Hideg K., Peuker S., Schultz P.G., Hubbell W.L. Site-directed spin labeling of a genetically encoded unnatural amino acid. Proc Natl Acad Sci U S A 2009, 106:21637-21642.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 21637-21642
-
-
Fleissner, M.R.1
Brustad, E.M.2
Kálai, T.3
Altenbach, C.4
Cascio, D.5
Peters, F.B.6
Hideg, K.7
Peuker, S.8
Schultz, P.G.9
Hubbell, W.L.10
|