Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats

Osteoporosis International

Volumn 24, Issue 3, 2013, Pages 969-978

  Sun, Y ^a   Shuang, F ^b   Chen, D M ^a   Zhou, R B ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b The 94th Hospital of PLA   (China)

Author keywords

Bone loss; Hydrogen molecule; Microgravity; Osteoblastic differentiation; Osteoclast differentiation; Oxidative stress

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; HYDROGEN; HYDROGEN WATER; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PEROXYNITRITE; PHOSPHORUS; REACTIVE OXYGEN METABOLITE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; THIOL DERIVATIVE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BONE DENSITY; CALCIUM BLOOD LEVEL; CELL DIFFERENTIATION; CHEMICAL COMPOSITION; CONTROLLED STUDY; CULTURE MEDIUM; ENERGY; ENZYME PHOSPHORYLATION; FEMUR; IN VITRO STUDY; IN VIVO STUDY; LUMBAR SPINE; MALE; MICROGRAVITY; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OXIDATIVE STRESS; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL; RAT; RIGIDITY; TISSUE LEVEL; UPREGULATION; WEIGHT BEARING;

ANIMALS; ANTIOXIDANTS; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMUR; HINDLIMB SUSPENSION; HYDROGEN; LUMBAR VERTEBRAE; OSTEOBLASTS; OSTEOCLASTS; OSTEOPOROSIS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; WATER; WEIGHTLESSNESS;

EID: 84878823021     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-012-2028-4     Document Type: Article

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