Modeled microgravity stimulates osteoclastogenesis and bone resorption by increasing osteoblast RANKL/OPG ratio

Journal of Cellular Biochemistry

Volumn 100, Issue 2, 2007, Pages 464-473

  Rucci, Nadia ^a   Rufo, Anna ^a   Alamanou, Marina ^a   Teti, Anna ^a,b  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b Department of Experimental Medicine ^*  (Italy)

Author keywords

Bone remodeling; Microgravity; Osteoblast; Osteoclast

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALKALINE PHOSPHATASE; BISBENZIMIDE; COLLAGEN TYPE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOLOGICAL MODEL; BIOREACTOR; BONE MARROW CULTURE; CELL CULTURE; CELL DEATH; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL SECRETION; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; MICROGRAVITY; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SKELETON; STAINING; TIME; WEIGHTLESSNESS;

ANIMALS; APOPTOSIS; BONE RESORPTION; CELL DIFFERENTIATION; CELLS, CULTURED; ENZYME ACTIVATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; OSTEOCLASTS; OSTEOPROTEGERIN; PHENOTYPE; RANK LIGAND; TRANSCRIPTION, GENETIC; WEIGHTLESSNESS;

EID: 33846450648     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21059     Document Type: Article

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