Simulated microgravity using the Random Positioning Machine inhibits differentiation and alters gene expression profiles of 2T3 preosteoblasts

American Journal of Physiology - Cell Physiology

Volumn 288, Issue 6 57-6, 2005, Pages

  Pardo, Steven J ^a   Patel, Mamta J ^a   Sykes, Michelle C ^a   Platt, Manu O ^a   Boyd, Nolan L ^a   Sorescu, George P ^a   Xu, Min ^c   Van Loon, Jack J W A ^d   Wang, May D ^a   Jo, Hanjoong ^a,b,e  

^a Emory University   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Amersham Biosciences   (United States)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

^e GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Alkaline phosphatase; Bone loss; Microarray; Osteomodulin; runx2

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 4; CATHEPSIN K; CYSTATIN C; OSTEOMODULIN; PARATHYROID HORMONE RECEPTOR 1; PROTEIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; ENZYME ACTIVITY; ENZYME REGULATION; IMMUNOBLOTTING; MICROGRAVITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; OSTEOPOROSIS; PRIORITY JOURNAL; RANDOMIZATION; REAL TIME POLYMERASE CHAIN REACTION; SPACE; STEM CELL; ANIMAL; CYTOLOGY; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; IN VITRO STUDY; METABOLISM; NASA DISCIPLINE CELL BIOLOGY; NON-NASA CENTER; PHYSIOLOGY; UPREGULATION; WEIGHTLESSNESS;

NASA DISCIPLINE CELL BIOLOGY; NON-NASA CENTER;

ANIMALS; CELL DIFFERENTIATION; DOWN-REGULATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; MICE; OSTEOBLASTS; UP-REGULATION; WEIGHTLESSNESS SIMULATION;

EID: 21144445382     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00222.2004     Document Type: Article

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