메뉴 건너뛰기




Volumn 125, Issue 6, 2013, Pages 932-943

The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress

Author keywords

aphakia mouse; calbindin D28k; development; MPTP; Parkinson's disease; substantia nigra

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CALBINDIN; TRANSCRIPTION FACTOR PITX3;

EID: 84878758640     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12160     Document Type: Article
Times cited : (48)

References (69)
  • 1
    • 0031059220 scopus 로고    scopus 로고
    • Vulnerability of midbrain dopaminergic neurons in calbindin-D28k- deficient mice: Lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver mice
    • Airaksinen M. S., Thoenen H., and, Meyer M., (1997) Vulnerability of midbrain dopaminergic neurons in calbindin-D28k-deficient mice: lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver mice. Eur. J. Neurosci. 9, 120-127.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 120-127
    • Airaksinen, M.S.1    Thoenen, H.2    Meyer, M.3
  • 2
    • 4043165474 scopus 로고    scopus 로고
    • Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons
    • Alberi L., Sgado P., and, Simon H. H,. (2004) Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons. Development 131, 3229-3236.
    • (2004) Development , vol.131 , pp. 3229-3236
    • Alberi, L.1    Sgado, P.2    Simon, H.H.3
  • 5
    • 0036935250 scopus 로고    scopus 로고
    • CNS expression pattern of Lmx1b and coexpression with ptx genes suggest functional cooperativity in the development of forebrain motor control systems
    • Asbreuk C. H., Vogelaar C. F., Hellemons A., Smidt M. P., and, Burbach J. P., (2002) CNS expression pattern of Lmx1b and coexpression with ptx genes suggest functional cooperativity in the development of forebrain motor control systems. Mol. Cell. Neurosci. 21, 410-420.
    • (2002) Mol. Cell. Neurosci. , vol.21 , pp. 410-420
    • Asbreuk, C.H.1    Vogelaar, C.F.2    Hellemons, A.3    Smidt, M.P.4    Burbach, J.P.5
  • 8
    • 0016423020 scopus 로고
    • Dopamine in dendrites of substantia nigra neurons: Suggestions for a role in dendritic terminals
    • Bjorklund A., and, Lindvall O., (1975) Dopamine in dendrites of substantia nigra neurons: suggestions for a role in dendritic terminals. Brain Res. 83, 531-537.
    • (1975) Brain Res. , vol.83 , pp. 531-537
    • Bjorklund, A.1    Lindvall, O.2
  • 10
    • 63849221600 scopus 로고    scopus 로고
    • Activity of neurochemically heterogeneous dopaminergic neurons in the substantia nigra during spontaneous and driven changes in brain state
    • Brown M. T., Henny P., Bolam J. P., and, Magill P. J., (2009) Activity of neurochemically heterogeneous dopaminergic neurons in the substantia nigra during spontaneous and driven changes in brain state. J. Neurosci. 29, 2915-2925.
    • (2009) J. Neurosci. , vol.29 , pp. 2915-2925
    • Brown, M.T.1    Henny, P.2    Bolam, J.P.3    Magill, P.J.4
  • 11
    • 0032816549 scopus 로고    scopus 로고
    • The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease
    • Damier P., Hirsch E. C., Agid Y., and, Graybiel A. M,. (1999) The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain, 122 (Pt 8), 1437-1448.
    • (1999) Brain , vol.122 , Issue.PART 8 , pp. 1437-1448
    • Damier, P.1    Hirsch, E.C.2    Agid, Y.3    Graybiel, A.M.4
  • 12
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • Dauer W., and, Przedborski S., (2003) Parkinson's disease: mechanisms and models. Neuron 39, 889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 13
    • 0242363670 scopus 로고    scopus 로고
    • Molecular pathways of neurodegeneration in Parkinson's disease
    • Dawson T. M., and, Dawson V. L,. (2003) Molecular pathways of neurodegeneration in Parkinson's disease. Science 302, 819-822.
    • (2003) Science , vol.302 , pp. 819-822
    • Dawson, T.M.1    Dawson, V.L.2
  • 14
    • 0018099290 scopus 로고
    • Catecholamine innervation of the basal forebrain. IV. Topography of the dopamine projection to the basal forebrain and neostriatum
    • Fallon J. H., and, Moore R. Y., (1978) Catecholamine innervation of the basal forebrain. IV. Topography of the dopamine projection to the basal forebrain and neostriatum. J. Comp. Neurol. 180, 545-580.
    • (1978) J. Comp. Neurol. , vol.180 , pp. 545-580
    • Fallon, J.H.1    Moore, R.Y.2
  • 15
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia nigra regional selectivity
    • Fearnley J. M., and, Lees A. J., (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114, 2283-2301.
    • (1991) Brain , vol.114 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 16
    • 66149085781 scopus 로고    scopus 로고
    • Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
    • Friling S., Andersson E., Thompson L. H., et al,. (2009) Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells. Proc. Natl Acad. Sci. USA 106, 7613-7618.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 7613-7618
    • Friling, S.1    Andersson, E.2    Thompson, L.H.3
  • 17
    • 84862889904 scopus 로고    scopus 로고
    • A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse
    • Fu Y., Yuan Y., Halliday G., Rusznak Z., Watson C., and, Paxinos G., (2012) A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse. Brain Struct. Funct. 217, 591-612.
    • (2012) Brain Struct. Funct. , vol.217 , pp. 591-612
    • Fu, Y.1    Yuan, Y.2    Halliday, G.3    Rusznak, Z.4    Watson, C.5    Paxinos, G.6
  • 18
    • 0028278417 scopus 로고
    • Sparing of the dopaminergic neurons containing calbindin-D28k and of the dopaminergic mesocortical projections in weaver mutant mice
    • Gaspar P., Ben Jelloun N., and, Febvret A., (1994) Sparing of the dopaminergic neurons containing calbindin-D28k and of the dopaminergic mesocortical projections in weaver mutant mice. Neuroscience 61, 293-305.
    • (1994) Neuroscience , vol.61 , pp. 293-305
    • Gaspar, P.1    Ben Jelloun, N.2    Febvret, A.3
  • 19
    • 0023521580 scopus 로고
    • The neostriatal mosaic: III. Biochemical and developmental dissociation of patch-matrix mesostriatal systems
    • Gerfen C. R., Baimbridge K. G., and, Thibault J., (1987) The neostriatal mosaic: III. Biochemical and developmental dissociation of patch-matrix mesostriatal systems. J. Neurosci. 7, 3935-3944.
    • (1987) J. Neurosci. , vol.7 , pp. 3935-3944
    • Gerfen, C.R.1    Baimbridge, K.G.2    Thibault, J.3
  • 20
    • 0026712160 scopus 로고
    • Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: Sparing of calbindin-D28k-containing cells
    • German D. C., Manaye K. F., Sonsalla P. K., and, Brooks B. A., (1992) Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells. Ann. N. Y. Acad. Sci. 648, 42-62.
    • (1992) Ann. N. Y. Acad. Sci. , vol.648 , pp. 42-62
    • German, D.C.1    Manaye, K.F.2    Sonsalla, P.K.3    Brooks, B.A.4
  • 21
    • 0028838720 scopus 로고
    • Subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mRNA for the dopamine transporter: Comparison with the mRNA for the D2 receptor, tyrosine hydroxylase and calbindin immunoreactivity
    • Haber S. N., Ryoo H., Cox C., and, Lu W., (1995) Subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mRNA for the dopamine transporter: comparison with the mRNA for the D2 receptor, tyrosine hydroxylase and calbindin immunoreactivity. J. Comp. Neurol. 362, 400-410.
    • (1995) J. Comp. Neurol. , vol.362 , pp. 400-410
    • Haber, S.N.1    Ryoo, H.2    Cox, C.3    Lu, W.4
  • 22
    • 77949897463 scopus 로고    scopus 로고
    • The progression of pathology in Parkinson's disease
    • Halliday G. M., and, McCann H., (2010) The progression of pathology in Parkinson's disease. Ann. N. Y. Acad. Sci. 1184, 188-195.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1184 , pp. 188-195
    • Halliday, G.M.1    McCann, H.2
  • 23
    • 78649869204 scopus 로고    scopus 로고
    • Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease
    • Haubenberger D., Reinthaler E., Mueller J. C., et al,. (2011) Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease. Neurobiol. Aging 32, 302-307.
    • (2011) Neurobiol. Aging , vol.32 , pp. 302-307
    • Haubenberger, D.1    Reinthaler, E.2    Mueller, J.C.3
  • 24
    • 0013920522 scopus 로고
    • Dopamine (3-hydroxytyramine) and brain function
    • Hornykiewicz O., (1966) Dopamine (3-hydroxytyramine) and brain function. Pharmacol. Rev. 18, 925-964.
    • (1966) Pharmacol. Rev. , vol.18 , pp. 925-964
    • Hornykiewicz, O.1
  • 25
    • 0037786542 scopus 로고    scopus 로고
    • Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice
    • Hwang D. Y., Ardayfio P., Kang U. J., Semina E. V., and, Kim K. S., (2003) Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice. Brain Res. Mol. Brain Res. 114, 123-131.
    • (2003) Brain Res. Mol. Brain Res. , vol.114 , pp. 123-131
    • Hwang, D.Y.1    Ardayfio, P.2    Kang, U.J.3    Semina, E.V.4    Kim, K.S.5
  • 26
    • 14244261010 scopus 로고    scopus 로고
    • 3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: Behavioral characterization of a novel genetic model of Parkinson's disease
    • Hwang D. Y., Fleming S. M., Ardayfio P., Moran-Gates T., Kim H., Tarazi F. I., Chesselet M. F., and, Kim K. S., (2005) 3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: behavioral characterization of a novel genetic model of Parkinson's disease. J. Neurosci. 25, 2132-2137.
    • (2005) J. Neurosci. , vol.25 , pp. 2132-2137
    • Hwang, D.Y.1    Fleming, S.M.2    Ardayfio, P.3    Moran-Gates, T.4    Kim, H.5    Tarazi, F.I.6    Chesselet, M.F.7    Kim, K.S.8
  • 28
    • 64549121554 scopus 로고    scopus 로고
    • Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression
    • Jacobs F. M., van Erp S., van der Linden A. J., von Oerthel L., Burbach J. P., Smidt, and, M. P,. (2009) Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression. Development, 136, 531-540.
    • (2009) Development , vol.136 , pp. 531-540
    • Jacobs, F.M.1    Van Erp, S.2    Van Der Linden, A.J.3    Von Oerthel, L.4    Burbach, J.P.5    Smidt, M.P.6
  • 29
    • 80755152950 scopus 로고    scopus 로고
    • Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons
    • Jacobs F. M., Veenvliet J. V., Almirza W. H,. et al. (2011) Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons. Development 138, 5213-5222.
    • (2011) Development , vol.138 , pp. 5213-5222
    • Jacobs, F.M.1    Veenvliet, J.V.2    Almirza, W.H.3
  • 30
    • 84855972240 scopus 로고    scopus 로고
    • Neuropathology of sporadic Parkinson's disease: Evaluation and changes of concepts
    • Jellinger K. A., (2012) Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts. Mov. Disord. 27, 8-30.
    • (2012) Mov. Disord. , vol.27 , pp. 8-30
    • Jellinger, K.A.1
  • 31
    • 36248995866 scopus 로고    scopus 로고
    • Phenotypic segregation of aphakia and Pitx3-null mutants reveals that Pitx3 deficiency increases consolidation of specific movement components
    • Kas M. J., van der Linden A. J., Oppelaar H., von Oerthel L., Ramakers G. M., and, Smidt M. P., (2008) Phenotypic segregation of aphakia and Pitx3-null mutants reveals that Pitx3 deficiency increases consolidation of specific movement components. Behav. Brain Res. 186, 208-214.
    • (2008) Behav. Brain Res. , vol.186 , pp. 208-214
    • Kas, M.J.1    Van Der Linden, A.J.2    Oppelaar, H.3    Von Oerthel, L.4    Ramakers, G.M.5    Smidt, M.P.6
  • 33
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
    • Kish S. J., Shannak K., and, Hornykiewicz O., (1988) Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N. Engl. J. Med. 318, 876-880.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 876-880
    • Kish, S.J.1    Shannak, K.2    Hornykiewicz, O.3
  • 34
    • 4444374482 scopus 로고    scopus 로고
    • Functional diversity of ventral midbrain dopamine and GABAergic neurons
    • Korotkova T. M., Ponomarenko A. A., Brown R. E., and, Haas H. L., (2004) Functional diversity of ventral midbrain dopamine and GABAergic neurons. Mol. Neurobiol. 29, 243-259.
    • (2004) Mol. Neurobiol. , vol.29 , pp. 243-259
    • Korotkova, T.M.1    Ponomarenko, A.A.2    Brown, R.E.3    Haas, H.L.4
  • 35
    • 24344455580 scopus 로고    scopus 로고
    • Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease
    • Landau A. M., Luk K. C., Jones M. L., et al,. (2005) Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease. J. Exp. Med. 202, 575-581.
    • (2005) J. Exp. Med. , vol.202 , pp. 575-581
    • Landau, A.M.1    Luk, K.C.2    Jones, M.L.3
  • 36
    • 0025944895 scopus 로고
    • Dopaminergic neurons expressing calbindin in normal and parkinsonian monkeys
    • Lavoie B., and, Parent A., (1991) Dopaminergic neurons expressing calbindin in normal and parkinsonian monkeys. NeuroReport 2, 601-604.
    • (1991) NeuroReport , vol.2 , pp. 601-604
    • Lavoie, B.1    Parent, A.2
  • 37
    • 0035051188 scopus 로고    scopus 로고
    • Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding site
    • Lebel M., Gauthier Y., Moreau A., and, Drouin J., (2001) Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding site. J. Neurochem. 77, 558-567.
    • (2001) J. Neurochem. , vol.77 , pp. 558-567
    • Lebel, M.1    Gauthier, Y.2    Moreau, A.3    Drouin, J.4
  • 38
    • 0030513477 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons in the mouse that contain calbindin-D28k exhibit reduced vulnerability to MPTP-induced neurodegeneration
    • Liang C. L., Sinton C. M., Sonsalla P. K., and, German D. C,. (1996) Midbrain dopaminergic neurons in the mouse that contain calbindin-D28k exhibit reduced vulnerability to MPTP-induced neurodegeneration. Neurodegeneration 5, 313-318.
    • (1996) Neurodegeneration , vol.5 , pp. 313-318
    • Liang, C.L.1    Sinton, C.M.2    Sonsalla, P.K.3    German, D.C.4
  • 39
    • 0033570331 scopus 로고    scopus 로고
    • The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels
    • Liss B., Neu A., and, Roeper J., (1999) The weaver mouse gain-of-function phenotype of dopaminergic midbrain neurons is determined by coactivation of wvGirk2 and K-ATP channels. J. Neurosci. 19, 8839-8848.
    • (1999) J. Neurosci. , vol.19 , pp. 8839-8848
    • Liss, B.1    Neu, A.2    Roeper, J.3
  • 40
    • 79955939580 scopus 로고    scopus 로고
    • PITX3 gene polymorphism is associated with Parkinson's disease in Chinese population
    • Liu J., Sun Q. Y., Tang B. S., et al,. (2011) PITX3 gene polymorphism is associated with Parkinson's disease in Chinese population. Brain Res. 1392, 116-120.
    • (2011) Brain Res. , vol.1392 , pp. 116-120
    • Liu, J.1    Sun, Q.Y.2    Tang, B.S.3
  • 41
    • 0022203598 scopus 로고
    • Preservation of hypothalamic dopaminergic neurons in Parkinson's disease
    • Matzuk M. M., and, Saper C. B., (1985) Preservation of hypothalamic dopaminergic neurons in Parkinson's disease. Ann. Neurol. 18, 552-555.
    • (1985) Ann. Neurol. , vol.18 , pp. 552-555
    • Matzuk, M.M.1    Saper, C.B.2
  • 42
    • 20444376889 scopus 로고    scopus 로고
    • Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development
    • Maxwell S. L., Ho H. Y., Kuehner E., Zhao S., and, Li M., (2005) Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development. Dev. Biol. 282, 467-479.
    • (2005) Dev. Biol. , vol.282 , pp. 467-479
    • Maxwell, S.L.1    Ho, H.Y.2    Kuehner, E.3    Zhao, S.4    Li, M.5
  • 43
    • 0030067963 scopus 로고    scopus 로고
    • Cytoarchitectural distribution of calcium binding proteins in midbrain dopaminergic regions of rats and humans
    • McRitchie D. A., Hardman C. D., and, Halliday G. M., (1996) Cytoarchitectural distribution of calcium binding proteins in midbrain dopaminergic regions of rats and humans. J. Comp. Neurol. 364, 121-150.
    • (1996) J. Comp. Neurol. , vol.364 , pp. 121-150
    • McRitchie, D.A.1    Hardman, C.D.2    Halliday, G.M.3
  • 44
    • 46949106113 scopus 로고    scopus 로고
    • Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease
    • Mizuta I., Tsunoda T., Satake W., et al,. (2008) Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease. Hum. Genet. 124, 89-94.
    • (2008) Hum. Genet. , vol.124 , pp. 89-94
    • Mizuta, I.1    Tsunoda, T.2    Satake, W.3
  • 45
    • 65249180086 scopus 로고    scopus 로고
    • Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons
    • Mosharov E. V., Larsen K. E., Kanter E., et al,. (2009) Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. Neuron 62, 218-229.
    • (2009) Neuron , vol.62 , pp. 218-229
    • Mosharov, E.V.1    Larsen, K.E.2    Kanter, E.3
  • 47
    • 33644834168 scopus 로고    scopus 로고
    • Striatal neuroadaptation and rescue of locomotor deficit by L-dopa in aphakia mice, a model of Parkinson's disease
    • van den Munckhof P., Gilbert F., Chamberland M., Lévesque D., and, Drouin J., (2006) Striatal neuroadaptation and rescue of locomotor deficit by L-dopa in aphakia mice, a model of Parkinson's disease. J. Neurochem. 96, 160-170.
    • (2006) J. Neurochem. , vol.96 , pp. 160-170
    • Van Den Munckhof, P.1    Gilbert, F.2    Chamberland, M.3    Lévesque, D.4    Drouin, J.5
  • 48
    • 0029942834 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons in the mouse: Computer-assisted mapping
    • Nelson E. L., Liang C. L., Sinton C. M., and, German D. C., (1996) Midbrain dopaminergic neurons in the mouse: computer-assisted mapping. J. Comp. Neurol. 369, 361-371.
    • (1996) J. Comp. Neurol. , vol.369 , pp. 361-371
    • Nelson, E.L.1    Liang, C.L.2    Sinton, C.M.3    German, D.C.4
  • 49
    • 0032863378 scopus 로고    scopus 로고
    • Calretinin and calbindin-D28k in dopaminergic neurons of the rat midbrain: A triple-labeling immunohistochemical study
    • Nemoto C., Hida T., and, Arai R., (1999) Calretinin and calbindin-D28k in dopaminergic neurons of the rat midbrain: a triple-labeling immunohistochemical study. Brain Res. 846, 129-136.
    • (1999) Brain Res. , vol.846 , pp. 129-136
    • Nemoto, C.1    Hida, T.2    Arai, R.3
  • 51
    • 34848896595 scopus 로고    scopus 로고
    • Differences in neurogenic potential in floor plate cells along an anteroposterior location: Midbrain dopaminergic neurons originate from mesencephalic floor plate cells
    • Ono Y., Nakatani T., Sakamoto Y,. et al. (2007) Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells. Development 134, 3213-3225.
    • (2007) Development , vol.134 , pp. 3213-3225
    • Ono, Y.1    Nakatani, T.2    Sakamoto, Y.3
  • 53
    • 80052585299 scopus 로고    scopus 로고
    • Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons
    • Peng C., Aron L., Klein R., Li M., Wurst W., Prakash N., and, Le W., (2011) Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons. J. Neurosci. 31, 12802-12815.
    • (2011) J. Neurosci. , vol.31 , pp. 12802-12815
    • Peng, C.1    Aron, L.2    Klein, R.3    Li, M.4    Wurst, W.5    Prakash, N.6    Le, W.7
  • 54
    • 0035864962 scopus 로고    scopus 로고
    • A double-deletion mutation in the Pitx3 gene causes arrested lens development in aphakia mice
    • Rieger D. K., Reichenberger E., McLean W., Sidow A., and, Olsen B. R., (2001) A double-deletion mutation in the Pitx3 gene causes arrested lens development in aphakia mice. Genomics 72, 61-72.
    • (2001) Genomics , vol.72 , pp. 61-72
    • Rieger, D.K.1    Reichenberger, E.2    McLean, W.3    Sidow, A.4    Olsen, B.R.5
  • 55
    • 0030782462 scopus 로고    scopus 로고
    • Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP
    • Sanghera M. K., Manaye K., McMahon A., Sonsalla P. K., and, German D. C., (1997) Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP. NeuroReport 8, 3327-3331.
    • (1997) NeuroReport , vol.8 , pp. 3327-3331
    • Sanghera, M.K.1    Manaye, K.2    McMahon, A.3    Sonsalla, P.K.4    German, D.C.5
  • 56
    • 0030669179 scopus 로고    scopus 로고
    • Isolation of a new homeobox gene belonging to the Pitx/Rieg family: Expression during lens development and mapping to the aphakia region on mouse chromosome 19
    • Semina E. V., Reiter R. S., and, Murray J. C., (1997) Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19. Hum. Mol. Genet. 6, 2109-2116.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 2109-2116
    • Semina, E.V.1    Reiter, R.S.2    Murray, J.C.3
  • 59
    • 0034034739 scopus 로고    scopus 로고
    • A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b
    • Smidt M. P., Asbreuk C. H., Cox J. J., Chen H., Johnson R. L., and, Burbach J. P., (2000) A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nat. Neurosci. 3, 337-341.
    • (2000) Nat. Neurosci. , vol.3 , pp. 337-341
    • Smidt, M.P.1    Asbreuk, C.H.2    Cox, J.J.3    Chen, H.4    Johnson, R.L.5    Burbach, J.P.6
  • 61
    • 0013845176 scopus 로고
    • Influence of the substantia nigra on the concentration of 5-hydroxytryptamine and dopamine of the striatum
    • Sourkes T. L., and, Poirier L., (1965) Influence of the substantia nigra on the concentration of 5-hydroxytryptamine and dopamine of the striatum. Nature 207, 202-203.
    • (1965) Nature , vol.207 , pp. 202-203
    • Sourkes, T.L.1    Poirier, L.2
  • 62
    • 81255149611 scopus 로고    scopus 로고
    • The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease
    • Surmeier D. J., Guzman J. N., Sanchez-Padilla J., and, Schumacker P. T., (2011) The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease. Neuroscience 198, 221-231.
    • (2011) Neuroscience , vol.198 , pp. 221-231
    • Surmeier, D.J.1    Guzman, J.N.2    Sanchez-Padilla, J.3    Schumacker, P.T.4
  • 63
    • 0034595729 scopus 로고    scopus 로고
    • Calretinin-containing axons and neurons are resistant to an intrastriatal 6-hydroxydopamine lesion
    • Tsuboi K., Kimber T. A., and, Shults C. W., (2000) Calretinin-containing axons and neurons are resistant to an intrastriatal 6-hydroxydopamine lesion. Brain Res. 866, 55-64.
    • (2000) Brain Res. , vol.866 , pp. 55-64
    • Tsuboi, K.1    Kimber, T.A.2    Shults, C.W.3
  • 64
    • 0014259290 scopus 로고
    • Aphakia, a new mutation in the mouse
    • Varnum D. S., and, Stevens L. C., (1968) Aphakia, a new mutation in the mouse. J. Hered. 59, 147-150.
    • (1968) J. Hered. , vol.59 , pp. 147-150
    • Varnum, D.S.1    Stevens, L.C.2
  • 65
    • 0038389745 scopus 로고    scopus 로고
    • Transcriptional control of dopamine neuron development
    • Wallen A., and, Perlmann T., (2003) Transcriptional control of dopamine neuron development. Ann. N. Y. Acad. Sci. 991, 48-60.
    • (2003) Ann. N. Y. Acad. Sci. , vol.991 , pp. 48-60
    • Wallen, A.1    Perlmann, T.2
  • 66
    • 0025196543 scopus 로고
    • Relative Sparing in Parkinsons-Disease of Substantia-Nigra Dopamine Neurons Containing Calbindin-D28K
    • Yamada T., McGeer P. L., Baimbridge K. G., and, McGeer E. G., (1990) Relative Sparing in Parkinsons-Disease of Substantia-Nigra Dopamine Neurons Containing Calbindin-D28K. Brain Res. 526, 303-307.
    • (1990) Brain Res. , vol.526 , pp. 303-307
    • Yamada, T.1    McGeer, P.L.2    Baimbridge, K.G.3    McGeer, E.G.4
  • 69
    • 12144286982 scopus 로고    scopus 로고
    • Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons
    • Zhao S., Maxwell S., Jimenez-Beristain A., et al,. (2004) Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons. Eur. J. Neurosci. 19, 1133-1140.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1133-1140
    • Zhao, S.1    Maxwell, S.2    Jimenez-Beristain, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.