Energetics and location of phosphoinositide binding in human Kir2.1 channels

Journal of Biological Chemistry

Volumn 288, Issue 23, 2013, Pages 16726-16737

  D'Avanzo, Nazzareno ^a   Lee, Sun Joo ^a   Cheng, Wayland W L ^a   Nichols, Colin G ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5-BISPHOSPHATE; ANIONIC PHOSPHOLIPIDS; CHANNEL ACTIVATION; COMPUTATIONAL APPROACH; MULTIPLE ORIENTATIONS; PHOSPHOINOSITIDE BINDING; PHOSPHOINOSITIDES; SELECTIVE ACTIVATION;

PHOSPHOLIPIDS;

BINDING ENERGY;

INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; PHOSPHATIDYLINOSITIDE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHICKEN; COMPETITIVE INHIBITION; COMPUTER MODEL; CONTROLLED STUDY; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; SENSITIVITY ANALYSIS; STRUCTURAL HOMOLOGY;

LIPIDS; MOLECULAR DOCKING; MOLECULAR MODELING; PHOSPHATIDYLINOSITOL PHOSPHATASE; POTASSIUM CHANNELS;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MOLECULAR DOCKING SIMULATION; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BINDING;

PIPS;

EID: 84878754753     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.452540     Document Type: Article

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