Myocilin stimulates osteogenic differentiation of mesenchymal stem cells through mitogen-activated protein kinase signaling

Journal of Biological Chemistry

Volumn 288, Issue 23, 2013, Pages 16882-16894

  Kwon, Heung Sun ^a   Johnson, Thomas V ^a,b   Tomarev, Stanislav I ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MARROW-DERIVED MESENCHYMAL STEM CELLS; HUMAN BONE MARROW; MAP KINASE SIGNALING; MESENCHYMAL STEM CELL; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOBLAST DIFFERENTIATION; OSTEOGENIC DIFFERENTIATION; PRIMARY OPEN-ANGLE GLAUCOMA;

BONE; ENZYME ACTIVITY; FLOWCHARTING; MAMMALS; OSTEOBLASTS; STEM CELLS; TISSUE; TRANSCRIPTION FACTORS;

CELL CULTURE;

JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOCILIN; OSTEOPONTIN; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MASS; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; CORTICAL THICKNESS (BONE); ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; TRABECULAR BONE; UPREGULATION; WILD TYPE;

DIFFERENTIATION; GLYCOPROTEIN SECRETION; MAP KINASES (MAPKS); MESENCHYMAL STEM CELLS; MYOCILIN; OSTEOGENESIS; SIGNALING;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CYTOSKELETAL PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; EYE PROTEINS; GLYCOPROTEINS; HOMEODOMAIN PROTEINS; HUMANS; MAP KINASE SIGNALING SYSTEM; MESENCHYMAL STROMAL CELLS; MICE; MICE, MUTANT STRAINS; OSTEOBLASTS; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTORS; UP-REGULATION;

MUS; RATTUS;

EID: 84878748550     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.422972     Document Type: Article

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