Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach

Journal of Controlled Release

Volumn 170, Issue 1, 2013, Pages 132-140

  Duffy, Margaret R ^a   Parker, Alan L ^a,b   Kalkman, Eric R ^c   White, Katie ^a   Kovalskyy, Dmytro ^d,f   Kelly, Sharon M ^e   Baker, Andrew H ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b Institute of Medical Genetics   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

^f UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Adenovirus; Factor X; Small molecule inhibitors

Indexed keywords

BACTERIOPHAGES; BINS; ENZYME ACTIVITY; GENE TRANSFER; GENES; MOLECULES; THROUGHPUT; VIRUSES;

ADENOVIRUS; FACTOR X; HIGH-THROUGHPUT SCREENING; INTRACELLULAR TRANSPORT; INTRAVENOUS ADMINISTRATION; PHARMACOPHORE MODELING; SMALL MOLECULE INHIBITOR; TRANSDUCTION PATHWAYS;

GENE THERAPY;

BLOOD CLOTTING FACTOR 10;

ADENOVIRUS; ANIMAL EXPERIMENT; ANTIGEN RECOGNITION; ARTICLE; CELL TRANSPORT; CIRCULAR DICHROISM; CONTROLLED STUDY; FOLLOW UP; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN ADENOVIRUS 5; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO GENE TRANSFER; IN VITRO STUDY; INTRACELLULAR TRANSPORT; LIVER; LUNG CARCINOMA; MICROTUBULE; MOUSE; NONHUMAN; OVARY CARCINOMA; PHARMACOPHORE; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE; VIRAL GENE DELIVERY SYSTEM; VIRUS PARTICLE;

EID: 84878745753     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.05.007     Document Type: Article

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