Fratricide of natural killer cells dressed with tumor-derived NKG2D ligand

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 23, 2013, Pages 9421-9426

  Nakamura, Kyohei ^a,b   Nakayama, Masafumi ^a   Kawano, Mitsuko ^a   Amagai, Ryo ^a   Ishii, Tomonori ^b   Harigae, Hideo ^b   Ogasawara, Kouetsu ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Immune regulation; Immunological synapse; Intercellular membrane transfer

Indexed keywords

NATURAL KILLER CELL RECEPTOR NKG2D;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENDOCYTOSIS; MEMBRANE BIOLOGY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; TROGOCYTOSIS;

IMMUNE REGULATION; IMMUNOLOGICAL SYNAPSE; INTERCELLULAR MEMBRANE TRANSFER;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; DNA PRIMERS; ENDOCYTOSIS; FLOW CYTOMETRY; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; PERFORIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

MUS;

EID: 84878723164     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1300140110     Document Type: Article

References (47)

1. Yokoyama WM, Kim S, French AR (2004) The dynamic life of natural killer cells. Annu Rev Immunol 22:405-429.
2. Tefferi A, et al. (1994) Chronic natural killer cell lymphocytosis: A descriptive clinical study. Blood 84(8):2721-2725.
3. Morice WG, Leibson PJ, Tefferi A (2001) Natural killer cells and the syndrome of chronic natural killer cell lymphocytosis. Leuk Lymphoma 41(3-4):277-284.
4. Zhang R, Shah MV, Loughran TP, Jr. (2010) The root of many evils: Indolent large granular lymphocyte leukaemia and associated disorders. Hematol Oncol 28(3):105-117.
5. Ortaldo JR, Mason AT, O'Shea JJ (1995) Receptor-induced death in human natural killer cells: involvement of CD16. J Exp Med 181(1):339-344.
6. Taga K, et al. (1996) Target-induced death by apoptosis in human lymphokine-activated natural killer cells. Blood 87(6):2411-2418.
7. Jewett A, Bonavida B (1996) Target-induced inactivation and cell death by apoptosis in a subset of human NK cells. J Immunol 156(3):907-915.
8. Boissel N, et al. (2006) BCR/ABL oncogene directly controls MHC class I chainrelated molecule A expression in chronic myelogenous leukemia. J Immunol 176(8): 5108-5116.
9. Raulet DH (2003) Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol 3(10):781-790.
10. Champsaur M, Lanier LL (2010) Effect of NKG2D ligand expression on host immune responses. Immunol Rev 235(1):267-285.
11. Diefenbach A, Raulet DH (2001) Strategies for target cell recognition by natural killer cells. Immunol Rev 181:170-184.
12. Kärre K (2002) NK cells, MHC class I molecules and the missing self. Scand J Immunol 55(3):221-228.
13. Cerwenka A, Baron JL, Lanier LL (2001) Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo. Proc Natl Acad Sci USA 98(20):11521-11526.
14. Orange JS (2008) Formation and function of the lytic NK-cell immunological synapse. Nat Rev Immunol 8(9):713-725.
15. Dustin ML, Long EO (2010) Cytotoxic immunological synapses. Immunol Rev 235(1): 24-34.
16. Gilfillan S, Ho EL, Cella M, Yokoyama WM, Colonna M (2002) NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat Immunol 3(12): 1150-1155.
17. Giurisato E, et al. (2007) Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse. Mol Cell Biol 27(24):8583-8599.
18. Ogasawara K, et al. (2003) Impairment of NK cell function by NKG2D modulation in NOD mice. Immunity 18(1):41-51.
19. McCann FE, Eissmann P, Onfelt B, Leung R, Davis DM (2007) The activating NKG2D ligand MHC class I-related chain A transfers from target cells to NK cells in a manner that allows functional consequences. J Immunol 178(6):3418-3426.
20. Roda-Navarro P, Vales-Gomez M, Chisholm SE, Reyburn HT (2006) Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function. Proc Natl Acad Sci USA 103(30):11258-11263.
21. Joly E, Hudrisier D (2003) What is trogocytosis and what is its purpose? Nat Immunol 4(9):815.
22. Su MW, Walden PR, Golan DB, Eisen HN (1993) Cognate peptide-induced destruction of CD8+ cytotoxic T lymphocytes is due to fratricide. J Immunol 151(2):658-667.
23. van den Broek MF, Kägi D, Zinkernagel RM, Hengartner H (1995) Perforin dependence of natural killer cell-mediated tumor control in vivo. Eur J Immunol 25(12): 3514-3516.
24. Smyth MJ, et al. (2005) Activation of NK cell cytotoxicity. Mol Immunol 42(4):501-510.
25. Shibuya A, et al. (1996) DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity 4(6):573-581.
26. Cerwenka A, et al. (2000) Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12(6):721-727.
27. Cédile O, et al. (2010) The NKG2D ligands RAE-1δ and RAE-1e differ with respect to their receptor affinity, expression profiles and transcriptional regulation. PLoS ONE 5(10):e13466.
28. Nakayama M, et al. (2011) Natural killer (NK)-dendritic cell interactions generate MHC class II-dressed NK cells that regulate CD4+ T cells. Proc Natl Acad Sci USA 108(45): 18360-18365.
29. Roda-Navarro P, Reyburn HT (2007) Intercellular protein transfer at the NK cell immune synapse: Mechanisms and physiological significance. FASEB J 21(8):1636-1646.
30. Textor S, et al. (2011) NF-κ B-dependent upregulation of ICAM-1 by HPV16-E6/E7 facilitates NK cell/target cell interaction. Int J Cancer 128(5):1104-1113.
31. Liu D, et al. (2009) Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses. Immunity 31(1):99-109.
32. Lamaze C, Fujimoto LM, Yin HL, Schmid SL (1997) The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells. J Biol Chem 272(33):20332-20335.
33. Morcavallo A, et al. (2012) Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A. J Biol Chem 287(14):11422-11436.
34. Rejman J, Bragonzi A, Conese M (2005) Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes. Mol Ther 12(3):468-474.
35. Heuser JE, Anderson RG (1989) Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J Cell Biol 108(2):389-400.
36. McMahon HT, Boucrot E (2011) Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat Rev Mol Cell Biol 12(8):517-533.
37. Cone RE, Sprent J, Marchalonis JJ (1972) Antigen-binding specificity of isolated cellsurface immunoglobulin from thymus cells activated to histocompatibility antigens. Proc Natl Acad Sci USA 69(9):2556-2560.
38. Martínez-Martín N, et al. (2011) T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis. Immunity 35(2):208-222.
39. Dopfer EP, Minguet S, Schamel WW (2011) A new vampire saga: The molecular mechanism of T cell trogocytosis. Immunity 35(2):151-153.
40. Liu CC, et al. (1989) Resistance of cytolytic lymphocytes to perforin-mediated killing. Induction of resistance correlates with increase in cytotoxicity. J Exp Med 169(6):2211-2225.
41. Balaji KN, Schaschke N, Machleidt W, Catalfamo M, Henkart PA (2002) Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. J Exp Med 196(4):493-503.
42. Huang JF, et al. (1999) TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. Science 286(5441):952-954.
43. Su MW, et al. (2004) Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing. Eur J Immunol 34(9):2459-2470.
44. Leisegang M, et al. (2010) MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors. J Clin Invest 120(11):3869-3877.
45. Callard RE, Stark J, Yates AJ (2003) Fratricide: A mechanism for T memory-cell homeostasis. Trends Immunol 24(7):370-375.
46. Trambas CM, Griffiths GM (2003) Delivering the kiss of death. Nat Immunol 4(5): 399-403.
47. Ogasawara K, Benjamin J, Takaki R, Phillips JH, Lanier LL (2005) Function of NKG2D in natural killer cell-mediated rejection of mouse bone marrow grafts. Nat Immunol 6(9):938-945.