-
1
-
-
67650874081
-
Cancer statistics, 2009
-
19474385 10.3322/caac.20006
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin. 2009;59:225-49.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
22397650 10.1056/NEJMoa1113205 1:CAS:528:DC%2BC38XktFOgtbw%3D Erratum in: N Engl J Med 2012;367:976
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med. 2012;366:883-92. Erratum in: N Engl J Med 2012;367:976.
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
-
3
-
-
84861541343
-
Mutational processes molding the genomes of 21 breast cancers
-
22608084 10.1016/j.cell.2012.04.024 1:CAS:528:DC%2BC38Xntlyltrg%3D
-
Nik-Zainal S, Alexandrov LB, Wedge DC, Van Loo P, Greenman CD, Raine K, et al. Mutational processes molding the genomes of 21 breast cancers. Cell. 2012;149:979-93.
-
(2012)
Cell
, vol.149
, pp. 979-993
-
-
Nik-Zainal, S.1
Alexandrov, L.B.2
Wedge, D.C.3
Van Loo, P.4
Greenman, C.D.5
Raine, K.6
-
4
-
-
83455176258
-
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
-
22137795 10.1016/j.ccr.2011.11.005 1:CAS:528:DC%2BC3MXhs1Cit7%2FN
-
Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, Davidson CJ, et al. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell. 2011;20:810-7.
-
(2011)
Cancer Cell
, vol.20
, pp. 810-817
-
-
Snuderl, M.1
Fazlollahi, L.2
Le, L.P.3
Nitta, M.4
Zhelyazkova, B.H.5
Davidson, C.J.6
-
5
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
20981102 10.1038/nature09515 1:CAS:528:DC%2BC3cXhtlCjtrvI
-
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature. 2010;467:1114-7.
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
Antal, T.4
Leary, R.5
Fu, B.6
-
6
-
-
84869753284
-
Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns
-
22915640 10.1182/blood-2012-05-433540 1:CAS:528:DC%2BC38XhslKmu7nK
-
Schuh A, Becq J, Humphray S, Alexa A, Burns A, Clifford R, et al. Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns. Blood. 2012;120:4191-6.
-
(2012)
Blood
, vol.120
, pp. 4191-4196
-
-
Schuh, A.1
Becq, J.2
Humphray, S.3
Alexa, A.4
Burns, A.5
Clifford, R.6
-
7
-
-
83455171954
-
Many tumors in one: A daunting therapeutic prospect
-
22172718 10.1016/j.ccr.2011.11.018 1:CAS:528:DC%2BC3MXhs1Cit77N
-
Ene CI, Fine HA. Many tumors in one: a daunting therapeutic prospect. Cancer Cell. 2011;20:695-7.
-
(2011)
Cancer Cell
, vol.20
, pp. 695-697
-
-
Ene, C.I.1
Fine, H.A.2
-
8
-
-
79953158399
-
Exploring the genome of cancer cells: Progress and promise
-
21436442 10.1126/science.1204040 1:CAS:528:DC%2BC3MXjs1Cgtb0%3D
-
Stratton MR. Exploring the genome of cancer cells: progress and promise. Science. 2011;331:1553-8.
-
(2011)
Science
, vol.331
, pp. 1553-1558
-
-
Stratton, M.R.1
-
9
-
-
64749094310
-
The cancer genome
-
19360079 10.1038/nature07943 1:CAS:528:DC%2BD1MXksVehtb8%3D
-
Stratton MR, Campbell PJ, Futreal PA. The cancer genome. Nature. 2009;458:719-24.
-
(2009)
Nature
, vol.458
, pp. 719-724
-
-
Stratton, M.R.1
Campbell, P.J.2
Futreal, P.A.3
-
10
-
-
84860495296
-
Omics and therapy - A basis for precision medicine
-
22445068 10.1016/j.molonc.2012.02.009
-
Garay JP, Gray JW. Omics and therapy - a basis for precision medicine. Mol Oncol. 2012;6:128-39.
-
(2012)
Mol Oncol
, vol.6
, pp. 128-139
-
-
Garay, J.P.1
Gray, J.W.2
-
11
-
-
84856013431
-
Clonal evolution in cancer
-
22258609 10.1038/nature10762 1:CAS:528:DC%2BC38Xps1CrtA%3D%3D
-
Greaves M, Maley CC. Clonal evolution in cancer. Nature. 2012;481:306-13.
-
(2012)
Nature
, vol.481
, pp. 306-313
-
-
Greaves, M.1
Maley, C.C.2
-
12
-
-
44849093562
-
Oncogene addiction
-
18451130 10.1158/0008-5472.CAN-07-3293 1:CAS:528:DC%2BD1cXltlSmtrk%3D
-
Weinstein IB, Joe A. Oncogene addiction. Cancer Res. 2008;68:3077-80.
-
(2008)
Cancer Res
, vol.68
, pp. 3077-3080
-
-
Weinstein, I.B.1
Joe, A.2
-
13
-
-
84862523863
-
Sequence analysis of mutations and translocations across breast cancer subtypes
-
22722202 10.1038/nature11154 1:CAS:528:DC%2BC38XovFykur8%3D
-
Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature. 2012;486:405-9.
-
(2012)
Nature
, vol.486
, pp. 405-409
-
-
Banerji, S.1
Cibulskis, K.2
Rangel-Escareno, C.3
Brown, K.K.4
Carter, S.L.5
Frederick, A.M.6
-
14
-
-
84877028141
-
Comprehensive molecular portrait of human breast tumors
-
The Cancer Genome Atlas Network 10.1038/nature11412
-
The Cancer Genome Atlas Network. Comprehensive molecular portrait of human breast tumors. Nature. 2012;490:61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
15
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
The Cancer Genome Atlas Network 10.1038/nature11252
-
The Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012;487:330-6.
-
(2012)
Nature
, vol.487
, pp. 330-336
-
-
-
16
-
-
84866851740
-
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
-
22941188 10.1038/ng.2396 1:CAS:528:DC%2BC38Xht12jsrnF
-
Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet. 2012;44:1104-10.
-
(2012)
Nat Genet
, vol.44
, pp. 1104-1110
-
-
Peifer, M.1
Fernández-Cuesta, L.2
Sos, M.L.3
George, J.4
Seidel, D.5
Kasper, L.H.6
-
17
-
-
84866875666
-
Genetic landscape of liver cancer
-
10.1038/ng.2412 1:CAS:528:DC%2BC38XhsVSltbzE
-
Zhang Z. Genetic landscape of liver cancer. Nature Gen. 2012;44:1075-7.
-
(2012)
Nature Gen
, vol.44
, pp. 1075-1077
-
-
Zhang, Z.1
-
18
-
-
80051680291
-
A continuum model for tumor suppression
-
21833082 10.1038/nature10275 1:CAS:528:DC%2BC3MXhtVOku7zM
-
Berger AH, Knudson AG, Pandolfi PP. A continuum model for tumor suppression. Nature. 2011;476:163-9.
-
(2011)
Nature
, vol.476
, pp. 163-169
-
-
Berger, A.H.1
Knudson, A.G.2
Pandolfi, P.P.3
-
19
-
-
84871722734
-
Tumor markers in clinical practice: A review focusing on common solid cancers
-
22584792 10.1159/000338393
-
Duffy MJ. Tumor markers in clinical practice: a review focusing on common solid cancers. Med Princ Pract. 2013;22:4-11.
-
(2013)
Med Princ Pract
, vol.22
, pp. 4-11
-
-
Duffy, M.J.1
-
20
-
-
0000710215
-
Chromosome studies in human leukemia. II. Chronic granulocytic leukemia
-
14480645 1:STN:280:DyaF38%2Fot1Wmuw%3D%3D
-
Nowell PC, Hungerford DA. Chromosome studies in human leukemia. II. Chronic granulocytic leukemia. J Natl Cancer Inst. 1961;27:1013-35.
-
(1961)
J Natl Cancer Inst
, vol.27
, pp. 1013-1035
-
-
Nowell, P.C.1
Hungerford, D.A.2
-
21
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
11287972 10.1056/NEJM200104053441401 1:CAS:528:DC%2BD3MXivFGnu70%3D
-
Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-7.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
-
22
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
11870241 10.1056/NEJMoa011573 1:CAS:528:DC%2BD38XhsFOjsr8%3D
-
Kantarjian H, Sawyers C, Hochhaus A, Guilhot F, Schiffer C, Gambacorti-Passerini C, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med. 2002;346:645-52.
-
(2002)
N Engl J Med
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
Guilhot, F.4
Schiffer, C.5
Gambacorti-Passerini, C.6
-
23
-
-
84878677672
-
Treatments for chronic myeloid leukemia: A qualitative systematic review
-
22915985 1:CAS:528:DC%2BC38XhtFOltr%2FP
-
Ferdinand R, Mitchell SA, Batson S, Tumur I. Treatments for chronic myeloid leukemia: a qualitative systematic review. J Blood Med. 2012;3:51-76.
-
(2012)
J Blood Med
, vol.3
, pp. 51-76
-
-
Ferdinand, R.1
Mitchell, S.A.2
Batson, S.3
Tumur, I.4
-
24
-
-
84867136402
-
The growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL
-
23002203 10.1158/0008-5472.CAN-12-1276 1:CAS:528:DC%2BC38XhsVOqtLjL
-
Hantschel O, Grebien F, Superti-Furga G. The growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL. Cancer Res. 2012;72:4890-5.
-
(2012)
Cancer Res
, vol.72
, pp. 4890-4895
-
-
Hantschel, O.1
Grebien, F.2
Superti-Furga, G.3
-
25
-
-
84871396050
-
It's about time: Lessons for solid tumors from chronic myelogenous leukemia therapy
-
23204432 10.1158/1535-7163.MCT-12-0473 1:CAS:528:DC%2BC38XhvVSqt7vF
-
Westin JR, Kurzrock R. It's about time: lessons for solid tumors from chronic myelogenous leukemia therapy. Mol Cancer Ther. 2012;11:2549-55.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 2549-2555
-
-
Westin, J.R.1
Kurzrock, R.2
-
26
-
-
0035257549
-
Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials
-
10.1016/S0093-7754(01)90188-5 1:CAS:528:DC%2BD3MXjtFWqsr8%3D
-
Slamon D, Pegram M. Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials. Sem Oncol. 2001;28 Suppl 3:13-9.
-
(2001)
Sem Oncol
, vol.28
, Issue.SUPPL. 3
, pp. 13-19
-
-
Slamon, D.1
Pegram, M.2
-
27
-
-
84873993908
-
Current approaches and future directions in the treatment of HER2-positive breast cancer
-
22658319 10.1016/j.ctrv.2012.04.008 1:CAS:528:DC%2BC38XotVSqsro%3D
-
Hurvitz SA, Hu Y, O'Brien N, Finn RS. Current approaches and future directions in the treatment of HER2-positive breast cancer. Cancer Treat Rev. 2013;39:219-29.
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 219-229
-
-
Hurvitz, S.A.1
Hu, Y.2
O'Brien, N.3
Finn, R.S.4
-
28
-
-
0029053716
-
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas
-
7538656 1:CAS:528:DyaK2MXls1artb8%3D
-
Alimandi M, Romano A, Curia MC, Muraro R, Fedi P, Aaronson SA, et al. Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene. 1995;10:1813-21.
-
(1995)
Oncogene
, vol.10
, pp. 1813-1821
-
-
Alimandi, M.1
Romano, A.2
Curia, M.C.3
Muraro, R.4
Fedi, P.5
Aaronson, S.A.6
-
29
-
-
79952264098
-
New strategies in HER2-overexpressing breast cancer: Many combinations of targeted drugs available
-
21248299 10.1158/1078-0432.CCR-09-1947 1:CAS:528:DC%2BC3MXis1eit70%3D
-
Abramson V, Arteaga CL. New strategies in HER2-overexpressing breast cancer: many combinations of targeted drugs available. Clin Cancer Res. 2011;17:952-8.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 952-958
-
-
Abramson, V.1
Arteaga, C.L.2
-
30
-
-
79958296638
-
Trastuzumab in the adjuvant treatment of HER2-positive early breast cancer patients: A meta-analysis of published randomized controlled trials
-
21695277 10.1371/journal.pone.0021030 1:CAS:528:DC%2BC3MXnslCmtrs%3D
-
Yin W, Jiang Y, Shen Z, Shao Z, Lu J. Trastuzumab in the adjuvant treatment of HER2-positive early breast cancer patients: a meta-analysis of published randomized controlled trials. PLoS One. 2011;6:e21030.
-
(2011)
PLoS One
, vol.6
, pp. 21030
-
-
Yin, W.1
Jiang, Y.2
Shen, Z.3
Shao, Z.4
Lu, J.5
-
31
-
-
79957864200
-
The efficacy of HER2-targeted agents in metastatic breast cancer: A meta-analysis
-
21119031 10.1093/annonc/mdq593 1:STN:280:DC%2BC3MrkvFOmtQ%3D%3D
-
Harris CA, Ward RL, Dobbins TA, Drew AK, Pearson S. The efficacy of HER2-targeted agents in metastatic breast cancer: a meta-analysis. Ann Oncol. 2011;22:1308-17.
-
(2011)
Ann Oncol
, vol.22
, pp. 1308-1317
-
-
Harris, C.A.1
Ward, R.L.2
Dobbins, T.A.3
Drew, A.K.4
Pearson, S.5
-
32
-
-
73949090721
-
Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: An institutional-based review
-
19933921 10.1200/JCO.2008.19.9844 1:CAS:528:DC%2BC3cXhtF2rsr0%3D
-
Dawood S, Broglio K, Buzdar AU, Hortobagyi GN, Giordano SH. Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based review. J Clin Oncol. 2010;28:92-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 92-98
-
-
Dawood, S.1
Broglio, K.2
Buzdar, A.U.3
Hortobagyi, G.N.4
Giordano, S.H.5
-
33
-
-
0031684721
-
The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor, and target for therapy
-
10388110
-
Ross JS, Fletcher JA. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Oncologist. 1998;3:237-52.
-
(1998)
Oncologist
, vol.3
, pp. 237-252
-
-
Ross, J.S.1
Fletcher, J.A.2
-
34
-
-
84856223809
-
Dual HER2-targeted approaches in HER2-positive breast cancer
-
21956210 10.1007/s10549-011-1781-y
-
Ahn ER, Vogel CL. Dual HER2-targeted approaches in HER2-positive breast cancer. Breast Cancer Res Treat. 2012;131:371-83.
-
(2012)
Breast Cancer Res Treat
, vol.131
, pp. 371-383
-
-
Ahn, E.R.1
Vogel, C.L.2
-
35
-
-
84856444501
-
Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): A randomised phase 3 trial
-
22257523 10.1016/S1470-2045(11)70397-7 1:CAS:528:DC%2BC38XitVSmurc%3D
-
Untch M, Loibl S, Bischoff J, Eidtmann H, Kaufmann M, Blohmer JU, et al. Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial. Lancet Oncol. 2012;13:135-44.
-
(2012)
Lancet Oncol
, vol.13
, pp. 135-144
-
-
Untch, M.1
Loibl, S.2
Bischoff, J.3
Eidtmann, H.4
Kaufmann, M.5
Blohmer, J.U.6
-
36
-
-
84857236823
-
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): A randomised, open-label, multicentre, phase 3 trial
-
22257673 10.1016/S0140-6736(11)61847-3 1:CAS:528:DC%2BC38XisFWjsrs%3D
-
Baselga J, Bradbury I, Eidtmann H, Di Cosimo S, de Azambuja E, Aura C, et al. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Lancet. 2012;379:633-40.
-
(2012)
Lancet
, vol.379
, pp. 633-640
-
-
Baselga, J.1
Bradbury, I.2
Eidtmann, H.3
Di Cosimo, S.4
De Azambuja, E.5
Aura, C.6
-
37
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
22149875 10.1056/NEJMoa1113216 1:CAS:528:DC%2BC38XhtFSlt7Y%3D
-
Baselga J, Cortés J, Kim SB, Im SA, Hegg R, Im YH, et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med. 2012;366:109-19.
-
(2012)
N Engl J Med
, vol.366
, pp. 109-119
-
-
Baselga, J.1
Cortés, J.2
Kim, S.B.3
Im, S.A.4
Hegg, R.5
Im, Y.H.6
-
38
-
-
84868520609
-
Trastuzumab emtansine for HER2-positive advanced breast cancer
-
23020162 10.1056/NEJMoa1209124 1:CAS:528:DC%2BC38Xhs1ekt73M
-
Verma S, Miles D, Gianni L, Krop IE, Welslau M, Baselga J, et al. Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med. 2012;367:1783-91.
-
(2012)
N Engl J Med
, vol.367
, pp. 1783-1791
-
-
Verma, S.1
Miles, D.2
Gianni, L.3
Krop, I.E.4
Welslau, M.5
Baselga, J.6
-
39
-
-
84875092951
-
Anti-metastatic treatment in colorectal cancer: Targeting signaling pathways
-
Lemos C, Sack U, Schmid F, Juneja M, Stein U. Anti-metastatic treatment in colorectal cancer: targeting signaling pathways. Curr Pharm Des. 2013;9:841-63.
-
(2013)
Curr Pharm Des.
, vol.9
, pp. 841-863
-
-
Lemos, C.1
Sack, U.2
Schmid, F.3
Juneja, M.4
Stein, U.5
-
40
-
-
84871922121
-
Cetuximab-mediated tumor regression depends on innate and adaptive immune responses
-
22990672 10.1038/mt.2012.184 1:CAS:528:DC%2BC38XhtlGqt7vJ
-
Yang X, Zhang X, Mortenson ED, Radkevich-Brown O, Wang Y, Fu YX. Cetuximab-mediated tumor regression depends on innate and adaptive immune responses. Mol Ther. 2013;21:91-100.
-
(2013)
Mol Ther
, vol.21
, pp. 91-100
-
-
Yang, X.1
Zhang, X.2
Mortenson, E.D.3
Radkevich-Brown, O.4
Wang, Y.5
Fu, Y.X.6
-
41
-
-
20144381957
-
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry
-
15677699 10.1200/JCO.2005.08.037 1:CAS:528:DC%2BD2MXjt1Ckuro%3D
-
Chung KY, Shia J, Kemeny NE, Shah M, Schwartz GK, Tse A, et al. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol. 2005;23:1803-10.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1803-1810
-
-
Chung, K.Y.1
Shia, J.2
Kemeny, N.E.3
Shah, M.4
Schwartz, G.K.5
Tse, A.6
-
42
-
-
79957576342
-
A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer
-
21550229 10.1016/j.ejca.2011.03.031 1:CAS:528:DC%2BC3MXmvVejs7k%3D
-
Adelstein BA, Dobbins TA, Harris CA, Marschner IC, Ward RL. A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer. Eur J Cancer. 2011;47:1343-54.
-
(2011)
Eur J Cancer
, vol.47
, pp. 1343-1354
-
-
Adelstein, B.A.1
Dobbins, T.A.2
Harris, C.A.3
Marschner, I.C.4
Ward, R.L.5
-
43
-
-
84861656612
-
Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis
-
22118887 10.1016/j.ctrv.2011.11.002 1:CAS:528:DC%2BC38Xnsl2rurw%3D
-
Vale CL, Tierney JF, Fisher D, Adams RA, Kaplan R, Maughan TS, et al. Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis. Cancer Treat Rev. 2012;38:618-25.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 618-625
-
-
Vale, C.L.1
Tierney, J.F.2
Fisher, D.3
Adams, R.A.4
Kaplan, R.5
Maughan, T.S.6
-
44
-
-
84866756037
-
Epidermal growth factor receptor (EGFR) signaling and covalent EGFR inhibition in lung cancer
-
22915655 10.1200/JCO.2012.43.1825 1:CAS:528:DC%2BC38Xhs1Glt73O
-
Heuckmann JM, Rauh D, Thomas RK. Epidermal growth factor receptor (EGFR) signaling and covalent EGFR inhibition in lung cancer. J Clin Oncol. 2012;30:3417-20.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3417-3420
-
-
Heuckmann, J.M.1
Rauh, D.2
Thomas, R.K.3
-
45
-
-
84876999267
-
Should epidermal growth factor receptor tyrosine kinase inhibitors be considered ideal drugs for the treatment of selected advanced non-small cell lung cancer patients?
-
10.1016/j.ctrv.2012.09.001
-
Rossi A, Pasquale R, Esposito C, Normanno N. Should epidermal growth factor receptor tyrosine kinase inhibitors be considered ideal drugs for the treatment of selected advanced non-small cell lung cancer patients? Cancer Treat Rev. 2012. doi: 10.1016/j.ctrv.2012.09.001.
-
(2012)
Cancer Treat Rev
-
-
Rossi, A.1
Pasquale, R.2
Esposito, C.3
Normanno, N.4
-
46
-
-
84866601770
-
Timing of epidermal growth factor receptor tyrosine kinase inhibitor therapy in patients with lung cancer with EGFR mutations
-
22753908 10.1200/JCO.2012.43.1858 1:CAS:528:DC%2BC38Xhs1Glt7%2FI
-
Moran T, Sequist LV. Timing of epidermal growth factor receptor tyrosine kinase inhibitor therapy in patients with lung cancer with EGFR mutations. J Clin Oncol. 2012;30:3330-6.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3330-3336
-
-
Moran, T.1
Sequist, L.V.2
-
47
-
-
84861203302
-
EGFR-mutated oncogene-addicted non-small cell lung cancer: Current trends and future prospects
-
22119437 10.1016/j.ctrv.2011.10.003 1:CAS:528:DC%2BC38Xnt1Kltb0%3D
-
Soria JC, Mok TS, Cappuzzo F, Jänne PA. EGFR-mutated oncogene-addicted non-small cell lung cancer: current trends and future prospects. Cancer Treat Rev. 2012;38:416-30.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 416-430
-
-
Soria, J.C.1
Mok, T.S.2
Cappuzzo, F.3
Jänne, P.A.4
-
48
-
-
84857718958
-
New strategies in melanoma: Molecular testing in advanced disease
-
22275506 10.1158/1078-0432.CCR-11-2317
-
Woodman SE, Lazar AJ, Aldape KD, Davies MA. New strategies in melanoma: molecular testing in advanced disease. Clin Cancer Res. 2012;18:1195-200.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1195-1200
-
-
Woodman, S.E.1
Lazar, A.J.2
Aldape, K.D.3
Davies, M.A.4
-
49
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
20818844 10.1056/NEJMoa1002011 1:CAS:528:DC%2BC3cXhtVyksb3M
-
Flaherty KT, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med. 2010;363:809-19.
-
(2010)
N Engl J Med
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
Ribas, A.4
McArthur, G.A.5
Sosman, J.A.6
-
50
-
-
84863116743
-
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
-
22356324 10.1056/NEJMoa1112302 1:CAS:528:DC%2BC38XjtFOqtr0%3D
-
Sosman JA, Kim KB, Schuchter L, et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Engl J Med. 2012;366:707-15.
-
(2012)
N Engl J Med
, vol.366
, pp. 707-715
-
-
Sosman, J.A.1
Kim, K.B.2
Schuchter, L.3
-
51
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
21639808 10.1056/NEJMoa1103782 1:CAS:528:DC%2BC3MXosVeitbs%3D
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364:2507-16.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
-
52
-
-
84864285704
-
Dabrafenib in BRAF-mutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial
-
22735384 10.1016/S0140-6736(12)60868-X 1:CAS:528:DC%2BC38Xpt1SgtLg%3D
-
Hauschild A, Grob JJ, Demidov LV, Jouary T, Gutzmer R, Millward M, et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet. 2012;380:358-65.
-
(2012)
Lancet
, vol.380
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
Jouary, T.4
Gutzmer, R.5
Millward, M.6
-
53
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
20979469 10.1056/NEJMoa1006448 1:CAS:528:DC%2BC3cXhtlKitL%2FO Erratum in: N Engl J Med. 2011;364:588
-
Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, Maki RG, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010;363:1693-703. Erratum in: N Engl J Med. 2011;364:588.
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
Maki, R.G.6
-
54
-
-
80053386829
-
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
-
21933749 10.1016/S1470-2045(11)70232-7 1:CAS:528:DC%2BC3MXht1KmtrzL
-
Shaw AT, Yeap BY, Solomon BJ, Riely GJ, Gainor J, Engelman JA, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol. 2011;12:1004-12.
-
(2011)
Lancet Oncol
, vol.12
, pp. 1004-1012
-
-
Shaw, A.T.1
Yeap, B.Y.2
Solomon, B.J.3
Riely, G.J.4
Gainor, J.5
Engelman, J.A.6
-
55
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
20728210 10.1016/S0140-6736(10)61121-X 1:CAS:528:DC%2BC3cXhtVymt7zO Erratum in: Lancet 2010;376:1302
-
Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet. 2010;376:687-97. Erratum in: Lancet 2010;376:1302.
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
Chung, H.C.4
Shen, L.5
Sawaki, A.6
-
56
-
-
78449266238
-
Perspective on updated treatment guidelines for patients with gastrointestinal stromal tumors
-
20661913 10.1002/cncr.25267
-
Blay JY, von Mehren M, Blackstein ME. Perspective on updated treatment guidelines for patients with gastrointestinal stromal tumors. Cancer. 2010;116:5126-37.
-
(2010)
Cancer
, vol.116
, pp. 5126-5137
-
-
Blay, J.Y.1
Von Mehren, M.2
Blackstein, M.E.3
-
57
-
-
76749154578
-
Towards a global consensus in the treatment of gastrointestinal stromal tumor
-
20131998 10.1586/era.09.171
-
Reichardt P, Blay J-Y, von Mehren M. Towards a global consensus in the treatment of gastrointestinal stromal tumor. Expert Rev Anticancer Ther. 2010;10:221-32.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, pp. 221-232
-
-
Reichardt, P.1
Blay, J.-Y.2
Von Mehren, M.3
-
58
-
-
0030976173
-
Cancer undefeated
-
9164814 10.1056/NEJM199705293362206
-
Bailar JC, Gornik HL. Cancer undefeated. N Engl J Med. 1997;336:1569-74.
-
(1997)
N Engl J Med
, vol.336
, pp. 1569-1574
-
-
Bailar, J.C.1
Gornik, H.L.2
-
59
-
-
84870678428
-
Randomized controlled trials and comparative effectiveness research
-
23071239 10.1200/JCO.2012.42.2352
-
Hahn OM, Schilsky RL. Randomized controlled trials and comparative effectiveness research. J Clin Oncol. 2012;30:4194-201.
-
(2012)
J Clin Oncol
, vol.30
, pp. 4194-4201
-
-
Hahn, O.M.1
Schilsky, R.L.2
-
60
-
-
84863652136
-
Circumventing cancer drug resistance in the era of personalised medicine
-
22585993 10.1158/2159-8290.CD-12-0012 1:CAS:528:DC%2BC38XktVGntbo%3D
-
Garraway LA, Janne PA. Circumventing cancer drug resistance in the era of personalised medicine. Cancer Discovery. 2012;2:214-6.
-
(2012)
Cancer Discovery
, vol.2
, pp. 214-216
-
-
Garraway, L.A.1
Janne, P.A.2
-
61
-
-
80053238941
-
Delivering affordable cancer care in high-income countries
-
21958503 10.1016/S1470-2045(11)70141-3
-
Sullivan R, Peppercorn J, Sikora K, Zalcberg J, Meropol NJ, Amir E, et al. Delivering affordable cancer care in high-income countries. Lancet Oncol. 2011;12:933-80.
-
(2011)
Lancet Oncol
, vol.12
, pp. 933-980
-
-
Sullivan, R.1
Peppercorn, J.2
Sikora, K.3
Zalcberg, J.4
Meropol, N.J.5
Amir, E.6
-
62
-
-
68249134187
-
How much is life worth: Cetuximab, non-small cell lung cancer, and the 440 billion question
-
19564563 10.1093/jnci/djp177
-
Fojo T, Grady C. How much is life worth: cetuximab, non-small cell lung cancer, and the 440 billion question. J Natl Cancer Inst. 2009;101:1044-8.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1044-1048
-
-
Fojo, T.1
Grady, C.2
-
63
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
17452677 10.1200/JCO.2006.07.9525 1:CAS:528:DC%2BD2sXmvVWmsr0%3D
-
Moore MJ, Goldstein D, Hamm J, Figer A, Hecht JR, Gallinger S, et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol. 2007;25:1960-66.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
Figer, A.4
Hecht, J.R.5
Gallinger, S.6
-
64
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
20818862 10.1056/NEJMoa1001294 1:CAS:528:DC%2BC3cXhtVGlurrN
-
Kantoff PW, Higano CS, Shore ND, Berger ER, Small EJ, Penson DF, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med. 2010;363:411-22.
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
-
65
-
-
79951859649
-
Concerns about Provenge simmer as CMS ponders coverage
-
10.1093/jnci/djr041
-
Goozner M. Concerns about Provenge simmer as CMS ponders coverage. J Natl Cancer Instit. 2011;103:288-9.
-
(2011)
J Natl Cancer Instit
, vol.103
, pp. 288-289
-
-
Goozner, M.1
-
66
-
-
79955857876
-
Despite steep costs, payments for new cancer drugs make economic sense
-
21383714 10.1038/nm0311-244 1:CAS:528:DC%2BC3MXivVGgt7c%3D
-
Lichtenberg FR. Despite steep costs, payments for new cancer drugs make economic sense. Nat Med. 2011;17:244.
-
(2011)
Nat Med
, vol.17
, pp. 244
-
-
Lichtenberg, F.R.1
-
67
-
-
33846995628
-
Economics of new oncology drug development
-
17210942 10.1200/JCO.2006.09.0803
-
DiMasi JA, Grabowski HG. Economics of new oncology drug development. J Clin Oncol. 2007;25:209-16.
-
(2007)
J Clin Oncol
, vol.25
, pp. 209-216
-
-
Dimasi, J.A.1
Grabowski, H.G.2
-
68
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates
-
10.1038/nrd1470 1:CAS:528:DC%2BD2cXmtVOhtLs%3D
-
Kola I, Landis J. Can the pharmaceutical industry reduce attrition rates. Nature Rev Drug Discovery. 2004;3:711-5.
-
(2004)
Nature Rev Drug Discovery
, vol.3
, pp. 711-715
-
-
Kola, I.1
Landis, J.2
-
69
-
-
84859438491
-
Adaptive clinical trials in oncology
-
Berry DA. Adaptive clinical trials in oncology. Nat Rev Clin Oncol. 2012;8(9):199-207.
-
(2012)
Nat Rev Clin Oncol
, vol.8
, Issue.9
, pp. 199-207
-
-
Berry, D.A.1
-
70
-
-
70449420123
-
Use of archived specimens in evaluation of prognostic and predictive biomarkers
-
19815849 10.1093/jnci/djp335
-
Simon RM, Paik S, Hayes DF. Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst. 2009;101:1446-52.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1446-1452
-
-
Simon, R.M.1
Paik, S.2
Hayes, D.F.3
-
71
-
-
84868096570
-
Reducing death from cancer: What will it take?
-
10.1007/s13277-012-0425-0
-
Kripke M. Reducing death from cancer: what will it take? Tumor Biol. 2012;33:1275-8.
-
(2012)
Tumor Biol
, vol.33
, pp. 1275-1278
-
-
Kripke, M.1
|