-
1
-
-
0032752353
-
The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration
-
Meighan-Mantha RL, Hsu DKW, Guo Y, Brown SAN, Feng SY, et al. (1999) The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J Biol Chem 274: 33166-33176.
-
(1999)
J Biol Chem
, vol.274
, pp. 33166-33176
-
-
Meighan-Mantha, R.L.1
Hsu, D.K.W.2
Guo, Y.3
Brown, S.A.N.4
Feng, S.Y.5
-
2
-
-
0033843466
-
The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas
-
Feng SY, Guo Y, Factor VM, Thorgeirsson SS, Bell DW, et al. (2000) The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. Am J Pathol 156: 1253-1261.
-
(2000)
Am J Pathol
, vol.156
, pp. 1253-1261
-
-
Feng, S.Y.1
Guo, Y.2
Factor, V.M.3
Thorgeirsson, S.S.4
Bell, D.W.5
-
3
-
-
18244380611
-
A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis
-
Wiley SR, Cassiano L, Lofton T, Davis-Smith T, Winkles JA, et al. (2001) A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity 15: 837-846.
-
(2001)
Immunity
, vol.15
, pp. 837-846
-
-
Wiley, S.R.1
Cassiano, L.2
Lofton, T.3
Davis-Smith, T.4
Winkles, J.A.5
-
4
-
-
42949160019
-
The TWEAK-Fn14 cytokine-receptor axis: Discovery, biology and therapeutic targeting
-
Winkles JA, (2008) The TWEAK-Fn14 cytokine-receptor axis: Discovery, biology and therapeutic targeting. Nat Rev Drug Discov 7: 411-425.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 411-425
-
-
Winkles, J.A.1
-
5
-
-
80054865852
-
TWEAK/Fn14 pathway: An immunological switch for shaping tissue responses
-
Burkly LC, Michaelson JS, Zheng TS, (2011) TWEAK/Fn14 pathway: An immunological switch for shaping tissue responses. Immunol Rev 244: 99-114.
-
(2011)
Immunol Rev
, vol.244
, pp. 99-114
-
-
Burkly, L.C.1
Michaelson, J.S.2
Zheng, T.S.3
-
6
-
-
33744944082
-
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human
-
Bossen C, Ingold K, Tardivel A, Bodmer JL, Gaide O, et al. (2006) Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem 281: 13964-13971.
-
(2006)
J Biol Chem
, vol.281
, pp. 13964-13971
-
-
Bossen, C.1
Ingold, K.2
Tardivel, A.3
Bodmer, J.L.4
Gaide, O.5
-
7
-
-
84858627919
-
Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors
-
Varfolomeev E, Goncharov T, Maecker H, Zobel K, Komuves LG, et al. (2012) Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors. Sci Signal 5: ra22.
-
(2012)
Sci Signal
, vol.5
-
-
Varfolomeev, E.1
Goncharov, T.2
Maecker, H.3
Zobel, K.4
Komuves, L.G.5
-
8
-
-
0037390762
-
TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity
-
Donohue PJ, Richards CM, Brown SA, Hanscom HN, Buschman J, et al. (2003) TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity. Arterioscler Thromb Vasc Biol 23: 594-600.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 594-600
-
-
Donohue, P.J.1
Richards, C.M.2
Brown, S.A.3
Hanscom, H.N.4
Buschman, J.5
-
9
-
-
63249086636
-
Tumor necrosis factor-related weak inducer of apoptosis augments matrix metalloproteinase 9 (MMP-9) production in skeletal muscle through the activation of nuclear factor-κB-inducing kinase and p38 mitogen-activated protein kinase: A potential role of MMP-9 in myopathy
-
Li H, Mittal A, Paul PK, Kumar M, Srivastava DS, et al. (2009) Tumor necrosis factor-related weak inducer of apoptosis augments matrix metalloproteinase 9 (MMP-9) production in skeletal muscle through the activation of nuclear factor-κB-inducing kinase and p38 mitogen-activated protein kinase: A potential role of MMP-9 in myopathy. J Biol Chem 284: 4439-4450.
-
(2009)
J Biol Chem
, vol.284
, pp. 4439-4450
-
-
Li, H.1
Mittal, A.2
Paul, P.K.3
Kumar, M.4
Srivastava, D.S.5
-
10
-
-
61449148439
-
TNF-like weak inducer of apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-β-activated kinase 1
-
Kumar M, Makonchuk DY, Li H, Mittal A, Kumar A, (2009) TNF-like weak inducer of apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-β-activated kinase 1. J Immunol 182: 2439-2448.
-
(2009)
J Immunol
, vol.182
, pp. 2439-2448
-
-
Kumar, M.1
Makonchuk, D.Y.2
Li, H.3
Mittal, A.4
Kumar, A.5
-
11
-
-
72449164564
-
Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on Akt2 function
-
Fortin SP, Ennis MJ, Savitch BA, Carpentieri D, McDonough WS, et al. (2009) Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on Akt2 function. Mol Cancer Res 7: 1871-1881.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1871-1881
-
-
Fortin, S.P.1
Ennis, M.J.2
Savitch, B.A.3
Carpentieri, D.4
McDonough, W.S.5
-
12
-
-
33750300516
-
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-κB and correlate with poor patient outcome
-
Tran NL, McDonough WS, Savitch BA, Fortin SP, Winkles JA, et al. (2006) Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-κB and correlate with poor patient outcome. Cancer Res 66: 9535-9542.
-
(2006)
Cancer Res
, vol.66
, pp. 9535-9542
-
-
Tran, N.L.1
McDonough, W.S.2
Savitch, B.A.3
Fortin, S.P.4
Winkles, J.A.5
-
13
-
-
0141815764
-
TWEAK induces NF-κB2 p100 processing and long lasting NF-κB activation
-
Saitoh T, Nakayama M, Nakano H, Yagita H, Yamamoto N, et al. (2003) TWEAK induces NF-κB2 p100 processing and long lasting NF-κB activation. J Biol Chem 278: 36005-36012.
-
(2003)
J Biol Chem
, vol.278
, pp. 36005-36012
-
-
Saitoh, T.1
Nakayama, M.2
Nakano, H.3
Yagita, H.4
Yamamoto, N.5
-
14
-
-
47549097367
-
TWEAK-Fn14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNF-α
-
Vince JE, Chau D, Callus B, Wong WW, Hawkins CJ, et al. (2008) TWEAK-Fn14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNF-α. J Cell Biol 182: 171-184.
-
(2008)
J Cell Biol
, vol.182
, pp. 171-184
-
-
Vince, J.E.1
Chau, D.2
Callus, B.3
Wong, W.W.4
Hawkins, C.J.5
-
15
-
-
77749282951
-
TWEAK activates the non-canonical NF-κB pathway in murine renal tubular cells: Modulation of CCL21
-
Sanz AB, Sanchez-Nino MD, Izquierdo MC, Jakubowski A, Justo P, et al. (2010) TWEAK activates the non-canonical NF-κB pathway in murine renal tubular cells: Modulation of CCL21. PLoS One 5: e8955.
-
(2010)
PLoS One
, vol.5
-
-
Sanz, A.B.1
Sanchez-Nino, M.D.2
Izquierdo, M.C.3
Jakubowski, A.4
Justo, P.5
-
16
-
-
77952892382
-
Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-κB pathway
-
Brown SA, Ghosh A, Winkles JA, (2010) Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-κB pathway. J Biol Chem 285: 17432-17441.
-
(2010)
J Biol Chem
, vol.285
, pp. 17432-17441
-
-
Brown, S.A.1
Ghosh, A.2
Winkles, J.A.3
-
17
-
-
28344457483
-
TWEAK attenuates the transition from innate to adaptive immunity
-
Maecker H, Varfolomeev E, Kischkel F, Lawrence D, LeBlanc H, et al. (2005) TWEAK attenuates the transition from innate to adaptive immunity. Cell 123: 931-944.
-
(2005)
Cell
, vol.123
, pp. 931-944
-
-
Maecker, H.1
Varfolomeev, E.2
Kischkel, F.3
Lawrence, D.4
LeBlanc, H.5
-
18
-
-
24644478033
-
TWEAK induces liver progenitor cell proliferation
-
Jakubowski A, Ambrose C, Parr M, Lincecum JM, Wang MZ, et al. (2005) TWEAK induces liver progenitor cell proliferation. J Clin Invest 115: 2330-2340.
-
(2005)
J Clin Invest
, vol.115
, pp. 2330-2340
-
-
Jakubowski, A.1
Ambrose, C.2
Parr, M.3
Lincecum, J.M.4
Wang, M.Z.5
-
19
-
-
60449110144
-
TWEAK/Fn14 pathway: A nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis
-
Dohi T, Borodovsky A, Wu P, Shearstone JR, Kawashima R, et al. (2009) TWEAK/Fn14 pathway: A nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis. Gastroenterology 136: 912-923.
-
(2009)
Gastroenterology
, vol.136
, pp. 912-923
-
-
Dohi, T.1
Borodovsky, A.2
Wu, P.3
Shearstone, J.R.4
Kawashima, R.5
-
20
-
-
34648869728
-
Role of TWEAK and Fn14 in tumor biology
-
Winkles JA, Tran NL, Brown SA, Stains N, Cunliffe HE, et al. (2007) Role of TWEAK and Fn14 in tumor biology. Front Biosci 12: 2761-2771.
-
(2007)
Front Biosci
, vol.12
, pp. 2761-2771
-
-
Winkles, J.A.1
Tran, N.L.2
Brown, S.A.3
Stains, N.4
Cunliffe, H.E.5
-
21
-
-
33645851656
-
TWEAK and Fn14: New molecular targets for cancer therapy?
-
Winkles JA, Tran NL, Berens ME, (2005) TWEAK and Fn14: New molecular targets for cancer therapy? Cancer Lett 235: 11-17.
-
(2005)
Cancer Lett
, vol.235
, pp. 11-17
-
-
Winkles, J.A.1
Tran, N.L.2
Berens, M.E.3
-
22
-
-
36049022442
-
TWEAKing tissue remodeling by a multifunctional cytokine: Role of TWEAK/Fn14 pathway in health and disease
-
Burkly LC, Michaelson JS, Hahm K, Jakubowski A, Zheng TS, (2007) TWEAKing tissue remodeling by a multifunctional cytokine: Role of TWEAK/Fn14 pathway in health and disease. Cytokine 40: 1-16.
-
(2007)
Cytokine
, vol.40
, pp. 1-16
-
-
Burkly, L.C.1
Michaelson, J.S.2
Hahm, K.3
Jakubowski, A.4
Zheng, T.S.5
-
23
-
-
74549220324
-
Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms
-
Culp PA, Choi D, Zhang Y, Yin J, Seto P, et al. (2010) Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms. Clin Cancer Res 16: 497-508.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 497-508
-
-
Culp, P.A.1
Choi, D.2
Zhang, Y.3
Yin, J.4
Seto, P.5
-
24
-
-
84862698136
-
Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion
-
Whitsett TG, Cheng E, Inge L, Asrani K, Jameson NM, et al. (2012) Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion. Am J Pathol 181: 111-120.
-
(2012)
Am J Pathol
, vol.181
, pp. 111-120
-
-
Whitsett, T.G.1
Cheng, E.2
Inge, L.3
Asrani, K.4
Jameson, N.M.5
-
25
-
-
84875219244
-
The TWEAK receptor Fn14 is a therapeutic target in melanoma: Immunotoxins targeting Fn14 receptor for malignant melanoma treatment
-
Zhou H, Ekmekcioglu S, Marks JW, Mohamedali KA, Asrani K, et al. (2013) The TWEAK receptor Fn14 is a therapeutic target in melanoma: Immunotoxins targeting Fn14 receptor for malignant melanoma treatment. J Invest Dermatol 133: 1052-1062.
-
(2013)
J Invest Dermatol
, vol.133
, pp. 1052-1062
-
-
Zhou, H.1
Ekmekcioglu, S.2
Marks, J.W.3
Mohamedali, K.A.4
Asrani, K.5
-
26
-
-
84875000590
-
Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb
-
Chao DT, Su M, Tanlimco S, Sho M, Choi D, et al. (2013) Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb. J Cancer Res Clin Oncol 139: 315-325.
-
(2013)
J Cancer Res Clin Oncol
, vol.139
, pp. 315-325
-
-
Chao, D.T.1
Su, M.2
Tanlimco, S.3
Sho, M.4
Choi, D.5
-
27
-
-
79960091768
-
Development of an Fn14 agonistic antibody as an anti-tumor agent
-
Michaelson JS, Amatucci A, Kelly R, Su L, Garber E, et al. (2011) Development of an Fn14 agonistic antibody as an anti-tumor agent. MAbs 3: 362-375.
-
(2011)
MAbs
, vol.3
, pp. 362-375
-
-
Michaelson, J.S.1
Amatucci, A.2
Kelly, R.3
Su, L.4
Garber, E.5
-
28
-
-
84863454553
-
The anti-Fn14 antibody BIIB036 inhibits tumor growth in xenografts and patient derived primary tumor models and enhances efficacy of chemotherapeutic agents in multiple xenograft models
-
Michaelson JS, Kelly R, Yang L, Zhang X, Wortham K, et al. (2012) The anti-Fn14 antibody BIIB036 inhibits tumor growth in xenografts and patient derived primary tumor models and enhances efficacy of chemotherapeutic agents in multiple xenograft models. Cancer Biol Ther 13: 812-821.
-
(2012)
Cancer Biol Ther
, vol.13
, pp. 812-821
-
-
Michaelson, J.S.1
Kelly, R.2
Yang, L.3
Zhang, X.4
Wortham, K.5
-
29
-
-
10844249434
-
Soluble tumor necrosis factor-like weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice
-
Ho DH, Vu H, Brown SAN, Donohue PJ, Hanscom HN, et al. (2004) Soluble tumor necrosis factor-like weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice. Cancer Res 64: 8968-8972.
-
(2004)
Cancer Res
, vol.64
, pp. 8968-8972
-
-
Ho, D.H.1
Vu, H.2
Brown, S.A.N.3
Donohue, P.J.4
Hanscom, H.N.5
-
30
-
-
79960124328
-
Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells
-
Zhou H, Marks JW, Hittelman WN, Yagita H, Cheung LH, et al. (2011) Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells. Mol Cancer Ther 10: 1276-1288.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1276-1288
-
-
Zhou, H.1
Marks, J.W.2
Hittelman, W.N.3
Yagita, H.4
Cheung, L.H.5
-
31
-
-
0037377706
-
The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors
-
Tran NL, McDonough WS, Donohue PJ, Winkles JA, Berens TJ, et al. (2003) The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors. Am J Pathol 162: 1313-1321.
-
(2003)
Am J Pathol
, vol.162
, pp. 1313-1321
-
-
Tran, N.L.1
McDonough, W.S.2
Donohue, P.J.3
Winkles, J.A.4
Berens, T.J.5
-
32
-
-
51049115805
-
The fibroblast growth factor-inducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity
-
Willis AL, Tran NL, Chatigny JM, Charlton N, Vu H, et al. (2008) The fibroblast growth factor-inducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity. Mol Cancer Res 6: 725-734.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 725-734
-
-
Willis, A.L.1
Tran, N.L.2
Chatigny, J.M.3
Charlton, N.4
Vu, H.5
-
33
-
-
13544268326
-
The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NF-κB pathway activation and BCL-XL/BCL-W expression
-
Tran NL, McDonough WS, Savitch BA, Sawyer TF, Winkles JA, et al. (2005) The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NF-κB pathway activation and BCL-XL/BCL-W expression. J Biol Chem 280: 3483-3492.
-
(2005)
J Biol Chem
, vol.280
, pp. 3483-3492
-
-
Tran, N.L.1
McDonough, W.S.2
Savitch, B.A.3
Sawyer, T.F.4
Winkles, J.A.5
-
34
-
-
35348860287
-
Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma
-
Watts GS, Tran NL, Berens ME, Bhattacharyya AK, Nelson MA, et al. (2007) Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma. Int J Cancer 121: 2132-2139.
-
(2007)
Int J Cancer
, vol.121
, pp. 2132-2139
-
-
Watts, G.S.1
Tran, N.L.2
Berens, M.E.3
Bhattacharyya, A.K.4
Nelson, M.A.5
-
35
-
-
80755144050
-
Overexpression of Fn14 promotes androgen-independent prostate cancer progression through MMP-9 and correlates with poor treatment outcome
-
Huang M, Narita S, Tsuchiya N, Ma Z, Numakura K, et al. (2011) Overexpression of Fn14 promotes androgen-independent prostate cancer progression through MMP-9 and correlates with poor treatment outcome. Carcinogenesis 32: 1589-1596.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1589-1596
-
-
Huang, M.1
Narita, S.2
Tsuchiya, N.3
Ma, Z.4
Numakura, K.5
-
36
-
-
84864011846
-
Cdc42 and the guanine nucleotide exchange factors Ect2 and Trio mediate Fn14-induced migration and invasion of glioblastoma cells
-
Fortin SP, Ennis MJ, Schumacher CA, Zylstra-Diegel CR, Williams BO, et al. (2012) Cdc42 and the guanine nucleotide exchange factors Ect2 and Trio mediate Fn14-induced migration and invasion of glioblastoma cells. Mol Cancer Res 10: 958-968.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 958-968
-
-
Fortin, S.P.1
Ennis, M.J.2
Schumacher, C.A.3
Zylstra-Diegel, C.R.4
Williams, B.O.5
-
37
-
-
34247132376
-
Identification of soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) as a possible biomarker of subclinical atherosclerosis
-
Blanco-Colio LM, Martin-Ventura JL, Munoz-Garcia B, Orbe J, Paramo JA, et al. (2007) Identification of soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) as a possible biomarker of subclinical atherosclerosis. Arterioscler Thromb Vasc Biol 27: 916-922.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 916-922
-
-
Blanco-Colio, L.M.1
Martin-Ventura, J.L.2
Munoz-Garcia, B.3
Orbe, J.4
Paramo, J.A.5
-
38
-
-
65449164651
-
A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure
-
Jain M, Jakubowski A, Cui L, Shi J, Su L, et al. (2009) A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure. Circulation 119: 2058-2068.
-
(2009)
Circulation
, vol.119
, pp. 2058-2068
-
-
Jain, M.1
Jakubowski, A.2
Cui, L.3
Shi, J.4
Su, L.5
-
39
-
-
0344823964
-
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
-
Rubin JB, Kung AL, Klein RS, Chan JA, Sun Y, et al. (2003) A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc Nat Acad Sci USA 100: 13513-13518.
-
(2003)
Proc Nat Acad Sci USA
, vol.100
, pp. 13513-13518
-
-
Rubin, J.B.1
Kung, A.L.2
Klein, R.S.3
Chan, J.A.4
Sun, Y.5
-
40
-
-
77951120000
-
Alternative splicing and evolution: Diversification, exon definition and function
-
Keren H, Lev-Maor G, Ast G, (2010) Alternative splicing and evolution: Diversification, exon definition and function. Nat Rev Genet 11: 345-355.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 345-355
-
-
Keren, H.1
Lev-Maor, G.2
Ast, G.3
-
41
-
-
33746093941
-
TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules
-
Brown SAN, Hanscom HN, Vu H, Brew SA, Winkles JA, (2006) TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules. Biochem J 397: 297-304.
-
(2006)
Biochem J
, vol.397
, pp. 297-304
-
-
Brown, S.A.N.1
Hanscom, H.N.2
Vu, H.3
Brew, S.A.4
Winkles, J.A.5
-
42
-
-
42649119769
-
Picomole-level mapping of protein disulfides by mass spectrometry following partial reduction and alkylation
-
Foley SF, Sun Y, Zheng TS, Wen D, (2008) Picomole-level mapping of protein disulfides by mass spectrometry following partial reduction and alkylation. Anal Biochem 377: 95-104.
-
(2008)
Anal Biochem
, vol.377
, pp. 95-104
-
-
Foley, S.F.1
Sun, Y.2
Zheng, T.S.3
Wen, D.4
-
43
-
-
61449199479
-
Solution structure of the cysteine-rich domain in Fn14, a member of the tumor necrosis factor receptor superfamily
-
He F, Dang W, Saito K, Watanabe S, Kobayashi N, et al. (2009) Solution structure of the cysteine-rich domain in Fn14, a member of the tumor necrosis factor receptor superfamily. Protein Sci 18: 650-656.
-
(2009)
Protein Sci
, vol.18
, pp. 650-656
-
-
He, F.1
Dang, W.2
Saito, K.3
Watanabe, S.4
Kobayashi, N.5
-
44
-
-
0038708366
-
The Fn14 cytoplasmic tail binds tumour necrosis factor receptor associated factors 1, 2, 3 and 5 and mediates nuclear factor-κB activation
-
Brown SAN, Richards CM, Hanscom HN, Feng SL, Winkles JA, (2003) The Fn14 cytoplasmic tail binds tumour necrosis factor receptor associated factors 1, 2, 3 and 5 and mediates nuclear factor-κB activation. Biochem J 371: 395-403.
-
(2003)
Biochem J
, vol.371
, pp. 395-403
-
-
Brown, S.A.N.1
Richards, C.M.2
Hanscom, H.N.3
Feng, S.L.4
Winkles, J.A.5
-
45
-
-
0038242506
-
TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-κB through TNF receptor-associated factors
-
Han S, Yoon K, Lee K, Kim K, Jang H, et al. (2003) TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-κB through TNF receptor-associated factors. Biochem Biophys Res Commun 305: 789-796.
-
(2003)
Biochem Biophys Res Commun
, vol.305
, pp. 789-796
-
-
Han, S.1
Yoon, K.2
Lee, K.3
Kim, K.4
Jang, H.5
-
46
-
-
0035936797
-
The TNF and TNF receptor superfamilies: Integrating mammalian biology
-
Locksley RM, Killeen N, Lenardo MJ, (2001) The TNF and TNF receptor superfamilies: Integrating mammalian biology. Cell 104: 487-501.
-
(2001)
Cell
, vol.104
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
47
-
-
84862293697
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized
-
Valley CC, Lewis AK, Mudaliar DJ, Perlmutter JD, Braun AR, et al. (2012) Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized. J Biol Chem 287: 21265-21278.
-
(2012)
J Biol Chem
, vol.287
, pp. 21265-21278
-
-
Valley, C.C.1
Lewis, A.K.2
Mudaliar, D.J.3
Perlmutter, J.D.4
Braun, A.R.5
-
48
-
-
0034733682
-
A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
-
Chan FK, Chun HJ, Zheng L, Siegel RM, Bui KL, et al. (2000) A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. Science 288: 2351-2354.
-
(2000)
Science
, vol.288
, pp. 2351-2354
-
-
Chan, F.K.1
Chun, H.J.2
Zheng, L.3
Siegel, R.M.4
Bui, K.L.5
-
49
-
-
25444485148
-
Tumor necrosis factor receptor I from patients with tumor necrosis factor receptor-associated periodic syndrome interacts with wild-type tumor necrosis factor receptor I and induces ligand-independent NF-κB activation
-
Yousaf N, Gould DJ, Aganna E, Hammond L, Mirakian RM, et al. (2005) Tumor necrosis factor receptor I from patients with tumor necrosis factor receptor-associated periodic syndrome interacts with wild-type tumor necrosis factor receptor I and induces ligand-independent NF-κB activation. Arthritis Rheum 52: 2906-2916.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2906-2916
-
-
Yousaf, N.1
Gould, D.J.2
Aganna, E.3
Hammond, L.4
Mirakian, R.M.5
-
50
-
-
34247899117
-
Three is better than one: Pre-ligand receptor assembly in the regulation of TNF receptor signaling
-
Chan FK, (2007) Three is better than one: Pre-ligand receptor assembly in the regulation of TNF receptor signaling. Cytokine 37: 101-107.
-
(2007)
Cytokine
, vol.37
, pp. 101-107
-
-
Chan, F.K.1
-
51
-
-
0029069758
-
Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor
-
Naismith JH, Devine TQ, Brandhuber BJ, Sprang SR, (1995) Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor. J Biol Chem 270: 13303-13307.
-
(1995)
J Biol Chem
, vol.270
, pp. 13303-13307
-
-
Naismith, J.H.1
Devine, T.Q.2
Brandhuber, B.J.3
Sprang, S.R.4
-
52
-
-
85047695761
-
Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed-Sternberg cells
-
Horie R, Watanabe T, Morishita Y, Ito K, Ishida T, et al. (2002) Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed-Sternberg cells. Oncogene 21: 2493-2503.
-
(2002)
Oncogene
, vol.21
, pp. 2493-2503
-
-
Horie, R.1
Watanabe, T.2
Morishita, Y.3
Ito, K.4
Ishida, T.5
-
53
-
-
27444443054
-
Self-assembled RANK induces osteoclastogenesis ligand-independently
-
Kanazawa K, Kudo A, (2005) Self-assembled RANK induces osteoclastogenesis ligand-independently. J Bone Miner Res 20: 2053-2060.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 2053-2060
-
-
Kanazawa, K.1
Kudo, A.2
-
54
-
-
0035576001
-
Characterization of a CD40-dominant inhibitory receptor mutant
-
Mehl AM, Jones M, Rowe M, Brennan P, (2001) Characterization of a CD40-dominant inhibitory receptor mutant. J Immunol 167: 6388-6393.
-
(2001)
J Immunol
, vol.167
, pp. 6388-6393
-
-
Mehl, A.M.1
Jones, M.2
Rowe, M.3
Brennan, P.4
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