-
1
-
-
34547670602
-
Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer
-
Als AB, Dyrskjot L, von der MH et al. (2007) Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer. Clin Cancer Res 13: 4407-14
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4407-4414
-
-
Als, A.B.1
Dyrskjot, L.2
Von Der, M.H.3
-
2
-
-
77950929562
-
Melanoma: A model for testing new agents in combination therapies
-
Ascierto PA, Streicher HZ, Sznol M (2010) Melanoma: a model for testing new agents in combination therapies. J Transl Med 8:38
-
(2010)
J Transl Med
, vol.8
, pp. 38
-
-
Ascierto, P.A.1
Streicher, H.Z.2
Sznol, M.3
-
3
-
-
74949143594
-
Final version of 2009 AJCC melanoma staging and classification
-
Balch CM, Gershenwald JE, Soong SJ et al. (2009) Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 27:6199-206
-
(2009)
J Clin Oncol
, vol.27
, pp. 6199-6206
-
-
Balch, C.M.1
Gershenwald, J.E.2
Soong, S.J.3
-
4
-
-
77952892382
-
Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway
-
Brown SA, Ghosh A, Winkles JA (2010) Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway. J Biol Chem 285:17432-41
-
(2010)
J Biol Chem
, vol.285
, pp. 17432-17441
-
-
Brown, S.A.1
Ghosh, A.2
Winkles, J.A.3
-
5
-
-
33746093941
-
TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules
-
Brown SA, Hanscom HN, Vu H et al. (2006) TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules. Biochem J 397:297-304
-
(2006)
Biochem J
, vol.397
, pp. 297-304
-
-
Brown, S.A.1
Hanscom, H.N.2
Vu, H.3
-
6
-
-
36049022442
-
TWEAKing tissue remodeling by a multifunctional cytokine: Role of TWEAK/Fn14 pathway in health and disease
-
Burkly LC, Michaelson JS, Hahm K et al. (2007) TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease. Cytokine 40:1-16
-
(2007)
Cytokine
, vol.40
, pp. 1-16
-
-
Burkly, L.C.1
Michaelson, J.S.2
Hahm, K.3
-
7
-
-
71549169552
-
Construction and characterization of novel, recombinant immunotoxins targeting the Her2/neu oncogene product: In vitro and in vivo studies
-
Cao Y, Marks JD, Marks JW et al. (2009) Construction and characterization of novel, recombinant immunotoxins targeting the Her2/neu oncogene product: in vitro and in vivo studies. Cancer Res 69:8987-95
-
(2009)
Cancer Res
, vol.69
, pp. 8987-8995
-
-
Cao, Y.1
Marks, J.D.2
Marks, J.W.3
-
8
-
-
77449114899
-
Stability and DNA-binding ability of the bZIP dimers formed by the ATF-2 and c-Jun transcription factors
-
Carrillo RJ, Dragan AI, Privalov PL (2010) Stability and DNA-binding ability of the bZIP dimers formed by the ATF-2 and c-Jun transcription factors. J Mol Biol 396:431-40
-
(2010)
J Mol Biol
, vol.396
, pp. 431-440
-
-
Carrillo, R.J.1
Dragan, A.I.2
Privalov, P.L.3
-
9
-
-
0021743724
-
A study of tumor progression: The precursor lesions of superficial spreading and nodular melanoma
-
Clark WH Jr., Elder DE, Guerry D et al. (1984) A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma. Hum Pathol 15:1147-65
-
(1984)
Hum Pathol
, vol.15
, pp. 1147-1165
-
-
Clark Jr., W.H.1
Elder, D.E.2
Guerry, D.3
-
10
-
-
74549220324
-
Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms
-
Culp PA, Choi D, Zhang Y et al. (2010) Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms. Clin Cancer Res 16:497-508
-
(2010)
Clin Cancer Res
, vol.16
, pp. 497-508
-
-
Culp, P.A.1
Choi, D.2
Zhang, Y.3
-
11
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
Curtin JA, Fridlyand J, Kageshita T et al. (2005) Distinct sets of genetic alterations in melanoma. N Engl J Med 353:2135-47
-
(2005)
N Engl J Med
, vol.353
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
-
12
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C et al. (2002) Mutations of the BRAF gene in human cancer. Nature 417:949-54
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
13
-
-
0037435045
-
Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site
-
Do TN, Rosal RV, Drew L et al. (2003) Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site. Oncogene 22:1431-44
-
(2003)
Oncogene
, vol.22
, pp. 1431-1444
-
-
Do, T.N.1
Rosal, R.V.2
Drew, L.3
-
15
-
-
0035015266
-
Microtiter-based assay for evaluating the biological activity of ribosome-inactivating proteins
-
Hale ML (2001) Microtiter-based assay for evaluating the biological activity of ribosome-inactivating proteins. Pharmacol Toxicol 88:255-60
-
(2001)
Pharmacol Toxicol
, vol.88
, pp. 255-260
-
-
Hale, M.L.1
-
16
-
-
53949103143
-
Melanoma genetics and therapeutic approaches in the 21st century: Moving from the benchside to the bedside
-
Hocker TL, Singh MK, Tsao H (2008) Melanoma genetics and therapeutic approaches in the 21st century: moving from the benchside to the bedside. J Invest Dermatol 128:2575-95
-
(2008)
J Invest Dermatol
, vol.128
, pp. 2575-2595
-
-
Hocker, T.L.1
Singh, M.K.2
Tsao, H.3
-
17
-
-
80755144050
-
Overexpression of Fn14 promotes androgen-independent prostate cancer progression through MMP-9 and correlates with poor treatment outcome
-
Huang M, Narita S, Tsuchiya N et al. (2011) Overexpression of Fn14 promotes androgen-independent prostate cancer progression through MMP-9 and correlates with poor treatment outcome. Carcinogenesis 32:1589-96
-
(2011)
Carcinogenesis
, vol.32
, pp. 1589-1596
-
-
Huang, M.1
Narita, S.2
Tsuchiya, N.3
-
18
-
-
22544444514
-
Caspase-independent cell death
-
Kroemer G, Martin SJ (2005) Caspase-independent cell death. Nat Med 11:725-30
-
(2005)
Nat Med
, vol.11
, pp. 725-730
-
-
Kroemer, G.1
Martin, S.J.2
-
19
-
-
82355175278
-
Elevated fibroblast growth factorinducible 14 expression promotes gastric cancer growth via nuclear factor-kappaB and is associated with poor patient outcome
-
Kwon OH, Park SJ, Kang TW et al. (2012) Elevated fibroblast growth factorinducible 14 expression promotes gastric cancer growth via nuclear factor-kappaB and is associated with poor patient outcome. Cancer Lett 314:73-81
-
(2012)
Cancer Lett
, vol.314
, pp. 73-81
-
-
Kwon, O.H.1
Park, S.J.2
Kang, T.W.3
-
20
-
-
79960091768
-
Development of an Fn14 agonistic antibody as an anti-tumor agent
-
Michaelson JS, Amatucci A, Kelly R et al. (2011) Development of an Fn14 agonistic antibody as an anti-tumor agent. MAbs 3:362-75
-
(2011)
MAbs
, vol.3
, pp. 362-375
-
-
Michaelson, J.S.1
Amatucci, A.2
Kelly, R.3
-
21
-
-
77649315474
-
Therapeutic targeting of TWEAK/Fnl4 in cancer: Exploiting the intrinsic tumor cell killing capacity of the pathway
-
Michaelson JS, Burkly LC (2009) Therapeutic targeting of TWEAK/Fnl4 in cancer: exploiting the intrinsic tumor cell killing capacity of the pathway. Results Probl Cell Differ 49:145-60
-
(2009)
Results Probl Cell Differ
, vol.49
, pp. 145-160
-
-
Michaelson, J.S.1
Burkly, L.C.2
-
22
-
-
9144274970
-
SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model
-
Murray LJ, Abrams TJ, Long KR et al. (2003) SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clin Exp Metastasis 20:757-66
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 757-766
-
-
Murray, L.J.1
Abrams, T.J.2
Long, K.R.3
-
23
-
-
0037223197
-
Fibroblast growth factorinducible 14 mediates multiple pathways of TWEAK-induced cell death
-
Nakayama M, Ishidoh K, Kojima Y et al. (2003) Fibroblast growth factorinducible 14 mediates multiple pathways of TWEAK-induced cell death. J Immunol 170:341-8
-
(2003)
J Immunol
, vol.170
, pp. 341-348
-
-
Nakayama, M.1
Ishidoh, K.2
Kojima, Y.3
-
24
-
-
77949802161
-
Melanoma biomarker expression in melanocytic tumor progression: A tissue microarray study
-
Nazarian RM, Prieto VG, Elder DE et al. (2010) Melanoma biomarker expression in melanocytic tumor progression: a tissue microarray study. J Cutan Pathol 37(Suppl 1):41-7
-
(2010)
J Cutan Pathol
, vol.37
, Issue.SUPPL. 1
, pp. 41-47
-
-
Nazarian, R.M.1
Prieto, V.G.2
Elder, D.E.3
-
25
-
-
0029057959
-
Amino acid sequence analysis, gene construction, cloning, and expression of gelonin, a toxin derived from Gelonium multiflorum
-
Rosenblum MG, Kohr WA, Beattie KL et al. (1995) Amino acid sequence analysis, gene construction, cloning, and expression of gelonin, a toxin derived from Gelonium multiflorum. J Interferon Cytokine Res 15:547-55
-
(1995)
J Interferon Cytokine Res
, vol.15
, pp. 547-555
-
-
Rosenblum, M.G.1
Kohr, W.A.2
Beattie, K.L.3
-
26
-
-
0038793948
-
Apoptosis and melanoma chemoresistance
-
Soengas MS, Lowe SW (2003) Apoptosis and melanoma chemoresistance. Oncogene 22:3138-51
-
(2003)
Oncogene
, vol.22
, pp. 3138-3151
-
-
Soengas, M.S.1
Lowe, S.W.2
-
28
-
-
0037377706
-
The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors
-
Tran NL, McDonough WS, Donohue PJ et al. (2003) The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors. Am J Pathol 162:1313-21
-
(2003)
Am J Pathol
, vol.162
, pp. 1313-1321
-
-
Tran, N.L.1
McDonough, W.S.2
Donohue, P.J.3
-
29
-
-
33750300516
-
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome
-
Tran NL, McDonough WS, Savitch BA et al. (2006) Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome. Cancer Res 66:9535-42
-
(2006)
Cancer Res
, vol.66
, pp. 9535-9542
-
-
Tran, N.L.1
McDonough, W.S.2
Savitch, B.A.3
-
31
-
-
33744947841
-
Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis
-
Wang S, Zhan M, Yin J et al. (2006) Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis. Oncogene 25:3346-56
-
(2006)
Oncogene
, vol.25
, pp. 3346-3356
-
-
Wang, S.1
Zhan, M.2
Yin, J.3
-
32
-
-
35348860287
-
Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma
-
Watts GS, Tran NL, Berens ME et al. (2007) Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma. Int J Cancer 121:2132-9
-
(2007)
Int J Cancer
, vol.121
, pp. 2132-2139
-
-
Watts, G.S.1
Tran, N.L.2
Berens, M.E.3
-
33
-
-
0027332881
-
An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability
-
Whitlow M, Bell BA, Feng SL et al. (1993) An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability. Protein Eng 6:989-95
-
(1993)
Protein Eng
, vol.6
, pp. 989-995
-
-
Whitlow, M.1
Bell, B.A.2
Feng, S.L.3
-
34
-
-
51049115805
-
The fibroblast growth factorinducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity
-
Willis AL, Tran NL, Chatigny JM et al. (2008) The fibroblast growth factorinducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity. Mol Cancer Res 6: 725-34
-
(2008)
Mol Cancer Res
, vol.6
, pp. 725-734
-
-
Willis, A.L.1
Tran, N.L.2
Chatigny, J.M.3
-
35
-
-
42949160019
-
The TWEAK-Fn14 cytokine-receptor axis: Discovery, biology and therapeutic targeting
-
Winkles JA (2008) The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting. Nat Rev Drug Discov 7:411-25
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 411-425
-
-
Winkles, J.A.1
-
37
-
-
79960124328
-
Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells
-
Zhou H, Marks JW, Hittelman WN et al. (2011) Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells. Mol Cancer Ther 10:1276-88
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1276-1288
-
-
Zhou, H.1
Marks, J.W.2
Hittelman, W.N.3
|