Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses

Journal of Virology

Volumn 87, Issue 12, 2013, Pages 7015-7031

  Tomov, Vesselin T ^a   Osborne, Lisa C ^a   Dolfi, Douglas V ^a   Sonnenberg, Gregory F ^a   Monticelli, Laurel A ^a   Mansfield, Kathleen ^a   Virgin, Herbert W ^b   Artis, David ^a   Wherry, E John ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTEGRIN; CD103 ANTIGEN; GAMMA INTERFERON; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROGRAMMED DEATH 1 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITOPE MAPPING; FEMALE; GENE DOSAGE; GENE EXPRESSION REGULATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE HOMING; MOUSE; NONHUMAN; NOROVIRUS; NOROVIRUS INFECTION; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHYLOGENETIC TREE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; UNINDEXED SEQUENCE; UPREGULATION; VIRAL CLEARANCE; VIRUS CELL INTERACTION; VIRUS LOAD; VIRUS REPLICATION; VIRUS SHEDDING; VIRUS STRAIN;

ANIMALS; CALICIVIRIDAE INFECTIONS; CD8-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; EPITOPES, T-LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; GASTROENTERITIS; IMMUNODOMINANT EPITOPES; INTESTINAL MUCOSA; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED C57BL; NOROVIRUS;

MURINE NOROVIRUS; MUS; NOROVIRUS;

EID: 84878601329     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03389-12     Document Type: Article

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