Efficient topical delivery of plasmid DNA to lung in vivo mediated by putative triggered, PEGylated pDNA nanoparticles

Journal of Controlled Release

Volumn 154, Issue 3, 2011, Pages 275-284

  Aissaoui, Abderrahim ^a,c   Chami, Mohamed ^b   Hussein, Mahamoud ^a   Miller, Andrew D ^a,c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BASEL   (Switzerland)

^c ImuThes Ltd   (United Kingdom)

Author keywords

Cationic lipids; Cryo electron microscopy; DNA delivery; Lung transfection; Nanoparticles; Polyethylenimine

Indexed keywords

CATIONIC LIPIDS; CRYO-ELECTRON MICROSCOPY; DNA DELIVERY; LUNG TRANSFECTION; POLYETHYLENIMINES;

AMIDES; BIOLOGICAL ORGANS; BIOMOLECULES; DNA; DRUG THERAPY; ELECTRON MICROSCOPES; GLYCOLS; LIPOSOMES; MEDICAL IMAGING; PHOSPHOLIPIDS; TISSUE;

NANOPARTICLES;

CHOLESTERYLOXYCARBONYLPOLYETHYLENEGLYCOL 4600; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; LIPID; LIPOPLEX; LIPOSOME; MACROGOL DERIVATIVE; N',N' DIOCTADECYL N 4,8 DIAZA 10 AMINODECANOYLGLYCINAMIDE; NANOPARTICLE; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRONCHIOLE; BRONCHUS MUCOSA; CONTROLLED STUDY; DNA TRANSFECTION; DRUG FORMULATION; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE;

ANIMALS; DNA; LIPOSOMES; LUNG; MICE; NANOPARTICLES; PLASMIDS; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE;

EID: 80052552280     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.06.017     Document Type: Article

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