-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D,. Global cancer statistics. CA Cancer J Clin. 2011; 61: 69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
84859212951
-
Hepatocellular carcinoma
-
Forner A, Llovet JM, Bruix J,. Hepatocellular carcinoma. Lancet. 2012; 379: 1245-1255.
-
(2012)
Lancet
, vol.379
, pp. 1245-1255
-
-
Forner, A.1
Llovet, J.M.2
Bruix, J.3
-
3
-
-
79955401037
-
Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma
-
Villanueva A, Hoshida Y, Battiston C, et al. Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma. Gastroenterology. 2011; 140: 1501-1512.
-
(2011)
Gastroenterology
, vol.140
, pp. 1501-1512
-
-
Villanueva, A.1
Hoshida, Y.2
Battiston, C.3
-
4
-
-
84878532428
-
Worst prognosis of hypovascular hepatocellular carcinoma
-
Mayer J, Auriol J, Muscari F, et al. Worst prognosis of hypovascular hepatocellular carcinoma. J Hepatol. 2010; 52: 227.
-
(2010)
J Hepatol
, vol.52
, pp. 227
-
-
Mayer, J.1
Auriol, J.2
Muscari, F.3
-
5
-
-
58149241016
-
Inhibition of invasion and metastasis of hepatocellular carcinoma cells via targeting RhoC in vitro and in vivo
-
Wang W, Wu F, Fang F, Tao YM, Yang LY,. Inhibition of invasion and metastasis of hepatocellular carcinoma cells via targeting RhoC in vitro and in vivo. Clin Cancer Res. 2008; 14: 6804-6812.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6804-6812
-
-
Wang, W.1
Wu, F.2
Fang, F.3
Tao, Y.M.4
Yang, L.Y.5
-
6
-
-
73149115105
-
Novel role for epidermal growth factor-like domain 7 in metastasis of human hepatocellular carcinoma
-
Wu F, Yang LY, Li YF, Ou DP, Chen DP, Fan C,. Novel role for epidermal growth factor-like domain 7 in metastasis of human hepatocellular carcinoma. Hepatology. 2009; 50: 1839-1850.
-
(2009)
Hepatology
, vol.50
, pp. 1839-1850
-
-
Wu, F.1
Yang, L.Y.2
Li, Y.F.3
Ou, D.P.4
Chen, D.P.5
Fan, C.6
-
7
-
-
83855162908
-
FBI-1 promotes cell proliferation and enhances resistance to chemotherapy of hepatocellular carcinoma in vitro and in vivo
-
Fang F, Yang L, Tao Y, Qin W,. FBI-1 promotes cell proliferation and enhances resistance to chemotherapy of hepatocellular carcinoma in vitro and in vivo. Cancer. 2012; 118: 134-146.
-
(2012)
Cancer
, vol.118
, pp. 134-146
-
-
Fang, F.1
Yang, L.2
Tao, Y.3
Qin, W.4
-
8
-
-
84858708597
-
Heat shock factor 1 promotes invasion and metastasis of hepatocellular carcinoma in vitro and in vivo
-
Fang F, Chang R, Yang L,. Heat shock factor 1 promotes invasion and metastasis of hepatocellular carcinoma in vitro and in vivo. Cancer. 2012; 118: 1782-1794.
-
(2012)
Cancer
, vol.118
, pp. 1782-1794
-
-
Fang, F.1
Chang, R.2
Yang, L.3
-
9
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto E, Facchinetti V, Liu D, et al. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell. 2006; 127: 125-137.
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
-
10
-
-
33751079895
-
Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
-
Yang Q, Inoki K, Ikenoue T, Guan KL,. Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. Genes Dev. 2006; 20: 2820-2832.
-
(2006)
Genes Dev
, vol.20
, pp. 2820-2832
-
-
Yang, Q.1
Inoki, K.2
Ikenoue, T.3
Guan, K.L.4
-
11
-
-
77955488179
-
Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells
-
Lazorchak AS, Liu D, Facchinetti V, et al. Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells. Mol Cell. 2010; 39: 433-443.
-
(2010)
Mol Cell
, vol.39
, pp. 433-443
-
-
Lazorchak, A.S.1
Liu, D.2
Facchinetti, V.3
-
12
-
-
60549094969
-
Decreased expression of inhibitor of growth 4 correlated with poor prognosis of hepatocellular carcinoma
-
Fang F, Luo LB, Tao YM, Wu F, Yang LY,. Decreased expression of inhibitor of growth 4 correlated with poor prognosis of hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev. 2009; 18: 409-416.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 409-416
-
-
Fang, F.1
Luo, L.B.2
Tao, Y.M.3
Wu, F.4
Yang, L.Y.5
-
13
-
-
0034782172
-
Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97
-
Li Y, Tang ZY, Ye SL, et al. Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97. World J Gastroenterol. 2001; 7: 630-636.
-
(2001)
World J Gastroenterol
, vol.7
, pp. 630-636
-
-
Li, Y.1
Tang, Z.Y.2
Ye, S.L.3
-
14
-
-
0037250193
-
Establishment of a hepatocellular carcinoma cell line with unique metastatic characteristics through in vivo selection and screening for metastasis-related genes through cDNA microarray
-
Li Y, Tang Y, Ye L, et al. Establishment of a hepatocellular carcinoma cell line with unique metastatic characteristics through in vivo selection and screening for metastasis-related genes through cDNA microarray. J Cancer Res Clin Oncol. 2003; 129: 43-51.
-
(2003)
J Cancer Res Clin Oncol
, vol.129
, pp. 43-51
-
-
Li, Y.1
Tang, Y.2
Ye, L.3
-
15
-
-
4344589523
-
Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics
-
Li Y, Tian B, Yang J, et al. Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics. J Cancer Res Clin Oncol. 2004; 130: 460-468.
-
(2004)
J Cancer Res Clin Oncol
, vol.130
, pp. 460-468
-
-
Li, Y.1
Tian, B.2
Yang, J.3
-
16
-
-
3042739357
-
Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis
-
Wang W, Yang LY, Huang GW, et al. Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis. Br J Cancer. 2004; 90: 2349-2355.
-
(2004)
Br J Cancer
, vol.90
, pp. 2349-2355
-
-
Wang, W.1
Yang, L.Y.2
Huang, G.W.3
-
17
-
-
58749107000
-
Solitary large hepatocellular carcinoma: A specific subtype of hepatocellular carcinoma with good outcome after hepatic resection
-
Yang LY, Fang F, Ou DP, Wu W, Zeng ZJ, Wu F,. Solitary large hepatocellular carcinoma: a specific subtype of hepatocellular carcinoma with good outcome after hepatic resection. Ann Surg. 2009; 249: 118-123.
-
(2009)
Ann Surg
, vol.249
, pp. 118-123
-
-
Yang, L.Y.1
Fang, F.2
Ou, D.P.3
Wu, W.4
Zeng, Z.J.5
Wu, F.6
-
18
-
-
84861567957
-
MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma
-
Fang Y, Xue JL, Shen Q, Chen J, Tian L,. MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma. Hepatology. 2012; 55: 1852-1862.
-
(2012)
Hepatology
, vol.55
, pp. 1852-1862
-
-
Fang, Y.1
Xue, J.L.2
Shen, Q.3
Chen, J.4
Tian, L.5
-
19
-
-
83655184636
-
Activation of AKT is associated with metastasis of nasopharyngeal carcinoma
-
Liu Y, Chen LH, Yuan YW, Li QS, Sun AM, Guan J,. Activation of AKT is associated with metastasis of nasopharyngeal carcinoma. Tumor Biol. 2012; 33: 241-245.
-
(2012)
Tumor Biol
, vol.33
, pp. 241-245
-
-
Liu, Y.1
Chen, L.H.2
Yuan, Y.W.3
Li, Q.S.4
Sun, A.M.5
Guan, J.6
-
20
-
-
77952828838
-
Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis
-
Dey JH, Bianchi F, Voshol J, Bonenfant D, Oakeley EJ, Hynes NE,. Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis. Cancer Res. 2010; 70: 4151-4162.
-
(2010)
Cancer Res
, vol.70
, pp. 4151-4162
-
-
Dey, J.H.1
Bianchi, F.2
Voshol, J.3
Bonenfant, D.4
Oakeley, E.J.5
Hynes, N.E.6
-
21
-
-
78751544628
-
P28(GANK) overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1 alpha pathways
-
Fu J, Chen Y, Cao J, et al. p28(GANK) overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1 alpha pathways. Hepatology. 2011; 53: 181-192.
-
(2011)
Hepatology
, vol.53
, pp. 181-192
-
-
Fu, J.1
Chen, Y.2
Cao, J.3
-
22
-
-
70350704818
-
Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway
-
Li B, Tsao SW, Li YY, et al. Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. Int J Cancer. 2009; 125: 2576-2585.
-
(2009)
Int J Cancer
, vol.125
, pp. 2576-2585
-
-
Li, B.1
Tsao, S.W.2
Li, Y.Y.3
-
23
-
-
68049143326
-
Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis
-
Yang E, Boire A, Agarwal A, et al. Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis. Cancer Res. 2009; 69: 6223-6231.
-
(2009)
Cancer Res
, vol.69
, pp. 6223-6231
-
-
Yang, E.1
Boire, A.2
Agarwal, A.3
-
25
-
-
84863116289
-
Cyclooxygenase-2 and Akt mediate multiple growth-factor-induced epithelial-mesenchymal transition in human hepatocellular carcinoma
-
Ogunwobi OO, Wang T, Zhang L, Liu C,. Cyclooxygenase-2 and Akt mediate multiple growth-factor-induced epithelial-mesenchymal transition in human hepatocellular carcinoma. J Gastroenterol Hepatol. 2012; 27: 566-578.
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 566-578
-
-
Ogunwobi, O.O.1
Wang, T.2
Zhang, L.3
Liu, C.4
-
26
-
-
81155126047
-
Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer
-
Yoo YA, Kang MH, Lee HJ, et al. Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer. Cancer Res. 2011; 71: 7061-7070.
-
(2011)
Cancer Res
, vol.71
, pp. 7061-7070
-
-
Yoo, Y.A.1
Kang, M.H.2
Lee, H.J.3
-
27
-
-
70349329766
-
Inhibition of PI3 kinase/Akt pathway is required for BMP2-induced EMT and invasion
-
Kang MH, Kang HN, Kim JL, Kim JS, Oh SC, Yoo YA,. Inhibition of PI3 kinase/Akt pathway is required for BMP2-induced EMT and invasion. Oncol Rep. 2009; 22: 525-534.
-
(2009)
Oncol Rep
, vol.22
, pp. 525-534
-
-
Kang, M.H.1
Kang, H.N.2
Kim, J.L.3
Kim, J.S.4
Oh, S.C.5
Yoo, Y.A.6
-
28
-
-
0037728809
-
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines
-
Grille SJ, Bellacosa A, Upson J, et al. The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res. 2003; 63: 2172-2178.
-
(2003)
Cancer Res
, vol.63
, pp. 2172-2178
-
-
Grille, S.J.1
Bellacosa, A.2
Upson, J.3
-
29
-
-
36349011403
-
Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition
-
Julien S, Puig I, Caretti E, et al. Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition. Oncogene. 2007; 26: 7445-7456.
-
(2007)
Oncogene
, vol.26
, pp. 7445-7456
-
-
Julien, S.1
Puig, I.2
Caretti, E.3
-
30
-
-
33749344520
-
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
-
Lee TK, Poon TP, Yuen AP, et al. Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition. Clin Cancer Res. 2006; 12: 5369-5376.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5369-5376
-
-
Lee, T.K.1
Poon, T.P.2
Yuen, A.P.3
-
31
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA,. Epithelial-mesenchymal transitions in development and disease. Cell. 2009; 139: 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
32
-
-
70349729970
-
Epithelial-mesenchymal transition and cell cooperativity in metastasis
-
Tsuji T, Ibaragi S, Hu GF,. Epithelial-mesenchymal transition and cell cooperativity in metastasis. Cancer Res. 2009; 69: 7135-7139.
-
(2009)
Cancer Res
, vol.69
, pp. 7135-7139
-
-
Tsuji, T.1
Ibaragi, S.2
Hu, G.F.3
-
33
-
-
33749024777
-
Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
-
Christiansen J, Rajasekaran AK,. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res. 2006; 66: 8319-8326.
-
(2006)
Cancer Res
, vol.66
, pp. 8319-8326
-
-
Christiansen, J.1
Rajasekaran, A.K.2
-
34
-
-
77956178360
-
EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
-
Singh A, Settleman J,. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene. 2010; 34: 4741-4751.
-
(2010)
Oncogene
, vol.34
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
|