Assessment of cardiac proteome dynamics with heavy water: Slower protein synthesis rates in interfibrillar than subsarcolemmal mitochondria

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 9, 2013, Pages

  Kasumov, Takhar ^a   Dabkowski, Erinne R ^b   Shekar, Kadambari Chandra ^b   Li, Ling ^a   Ribeiro, Rogerio F ^b   Walsh, Kenneth ^c   Previs, Stephen F ^d   Sadygov, Rovshan G ^e   Willard, Belinda ^a   Stanley, William C ^b,f  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

^e University of Texas Medical Branch School of Medicine   (United States)

^f UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Deuterium; Heart; Heavy water; High resolution mass spectroscopy; Proteome dynamics; Proteomics

Indexed keywords

AMINO ACID; DEUTERIUM OXIDE; DRINKING WATER; MITOCHONDRIAL PROTEIN; PROTEOME;

ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; HALF LIFE TIME; HEART; HEART MITOCHONDRION; LIVER MITOCHONDRION; MALE; MASS SPECTROMETRY; MUSCLE FIBRIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; RAT;

EID: 84878540619     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00933.2012     Document Type: Article

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