Measuring protein synthesis using metabolic 2H labeling, high-resolution mass spectrometry, and an algorithm

Analytical Biochemistry

Volumn 412, Issue 1, 2011, Pages 47-55

  Kasumov, Takhar ^a   Ilchenko, Serguey ^b   Li, Ling ^a   Rachdaoui, Nadia ^b   Sadygov, Rovshan G ^c   Willard, Belinda ^b   McCullough, Arthur J ^a   Previs, Stephen ^b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Albumin; Heavy water; High resolution mass spectrometry; Isotopomers; Mass isotopomer distribution; Modeling; Protein synthesis; Rat

Indexed keywords

AMINO ACIDS; DATA HANDLING; DESORPTION; ESTIMATION; FREE FLIGHT; HEAVY WATER; ISOTOPES; MASS SPECTROMETRY; MODELS; PEPTIDES; RATING;

ALBUMIN; HIGH RESOLUTION MASS SPECTROMETRY; ISOTOPOMER DISTRIBUTIONS; ISOTOPOMERS; PROTEIN SYNTHESIS;

BIOSYNTHESIS;

ALBUMIN; AMINO ACID; DEUTERIUM;

ALGORITHM; ANIMAL EXPERIMENT; ARTICLE; FOURIER TRANSFORM MASS SPECTROMETRY; KINETICS; MALE; MASS SPECTROMETRY; MATHEMATICAL MODEL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEASUREMENT; NONHUMAN; NUTRITIONAL STATUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; PURIFICATION; RAT; RELIABILITY; TISSUE SPECIFICITY;

RATTUS;

EID: 79952444247     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.01.021     Document Type: Article

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