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Volumn 12, Issue 11, 2013, Pages 1688-1695

Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response

Author keywords

DNA damage response; Ionizing radiation; Nucleus; Protein acetylation; Quantitative proteomics

Indexed keywords

ACYLTRANSFERASE; E1A ASSOCIATED P300 PROTEIN; LYSINE; METHYLTRANSFERASE; NUCLEAR PROTEIN; PROTEIN P53;

EID: 84878524313     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.24758     Document Type: Article
Times cited : (29)

References (36)
  • 1
    • 80053555789 scopus 로고    scopus 로고
    • More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
    • PMID:21968989
    • Lukas J, Lukas C, Bartek J. More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance. Nat Cell Biol 2011; 13:1161-9; PMID:21968989; http://dx.doi.org/10.1038/ncb2344
    • (2011) Nat Cell Biol , vol.13 , pp. 1161-1169
    • Lukas, J.1    Lukas, C.2    Bartek, J.3
  • 2
    • 77953148666 scopus 로고    scopus 로고
    • Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response
    • PMID:20164059
    • Bennetzen MV, Larsen DH, Bunkenborg J, Bartek J, Lukas J, Andersen JS. Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response. Mol Cell Proteomics 2010; 9:1314-23; PMID:20164059; http://dx.doi.org/10.1074/mcp.M900616-MCP200
    • (2010) Mol Cell Proteomics , vol.9 , pp. 1314-1323
    • Bennetzen, M.V.1    Larsen, D.H.2    Bunkenborg, J.3    Bartek, J.4    Lukas, J.5    Andersen, J.S.6
  • 3
    • 34249947699 scopus 로고    scopus 로고
    • ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
    • PMID:17525332
    • Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, et al. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007; 316:1160-6; PMID:17525332; http://dx.doi.org/10.1126/science.1140321
    • (2007) Science , vol.316 , pp. 1160-1166
    • Matsuoka, S.1    Ballif, B.A.2    Smogorzewska, A.3    McDonald III, E.R.4    Hurov, K.E.5    Luo, J.6
  • 4
    • 84864687923 scopus 로고    scopus 로고
    • Histone deacetylase complexes as caretakers of genome stability
    • PMID:22722985
    • Lahue RS, Frizzell A. Histone deacetylase complexes as caretakers of genome stability. Epigenetics 2012; 7:806-10; PMID:22722985; http://dx.doi.org/10.4161/epi.20922
    • (2012) Epigenetics , vol.7 , pp. 806-810
    • Lahue, R.S.1    Frizzell, A.2
  • 5
    • 80053064491 scopus 로고    scopus 로고
    • The impact of acetylation and deacetylation on the p53 pathway
    • PMID:21748595
    • Brooks CL, Gu W. The impact of acetylation and deacetylation on the p53 pathway. Protein Cell 2011; 2:456-62; PMID:21748595; http://dx.doi.org/10.1007/ s13238-011-1063-9
    • (2011) Protein Cell , vol.2 , pp. 456-462
    • Brooks, C.L.1    Gu, W.2
  • 6
    • 77953482819 scopus 로고    scopus 로고
    • The p53 response element and transcriptional repression
    • PMID:20160511
    • Wang B, Xiao Z, Ko HL, Ren EC. The p53 response element and transcriptional repression. Cell Cycle 2010; 9:870-9; PMID:20160511; http://dx.doi.org/10.4161/cc.9.5.10825
    • (2010) Cell Cycle , vol.9 , pp. 870-879
    • Wang, B.1    Xiao, Z.2    Ko, H.L.3    Ren, E.C.4
  • 7
    • 84863794131 scopus 로고    scopus 로고
    • The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3
    • PMID:22713239
    • Love IM, Sekaric P, Shi D, Grossman SR, Androphy EJ. The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3. Cell Cycle 2012; 11:2458-66; PMID:22713239; http://dx.doi.org/10.4161/cc.20864
    • (2012) Cell Cycle , vol.11 , pp. 2458-2466
    • Love, I.M.1    Sekaric, P.2    Shi, D.3    Grossman, S.R.4    Androphy, E.J.5
  • 8
    • 84875224166 scopus 로고    scopus 로고
    • Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination
    • PMID:23377543
    • Tang J, Cho NW, Cui G, Manion EM, Shanbhag NM, Botuyan MV, et al. Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat Struct Mol Biol 2013; 20:317-25; PMID:23377543; http://dx.doi.org/10.1038/nsmb.2499
    • (2013) Nat Struct Mol Biol , vol.20 , pp. 317-325
    • Tang, J.1    Cho, N.W.2    Cui, G.3    Manion, E.M.4    Shanbhag, N.M.5    Botuyan, M.V.6
  • 9
    • 79551529513 scopus 로고    scopus 로고
    • Chromatin dynamics and the repair of DNA double strand breaks
    • PMID:21212734
    • Xu Y, Price BD. Chromatin dynamics and the repair of DNA double strand breaks. Cell Cycle 2011; 10:261-7; PMID:21212734; http://dx.doi.org/10.4161/cc. 10.2.14543
    • (2011) Cell Cycle , vol.10 , pp. 261-267
    • Xu, Y.1    Price, B.D.2
  • 10
    • 68949212379 scopus 로고    scopus 로고
    • Lysine acetylation targets proteincomplexes and co-regulates major cellular functions
    • PMID:19608861
    • Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, et al. Lysine acetylation targets proteincomplexes and co-regulates major cellular functions. Science 2009; 325:834-40; PMID:19608861; http://dx.doi.org/10.1126/ science.1175371
    • (2009) Science , vol.325 , pp. 834-840
    • Choudhary, C.1    Kumar, C.2    Gnad, F.3    Nielsen, M.L.4    Rehman, M.5    Walther, T.C.6
  • 11
    • 84860325854 scopus 로고    scopus 로고
    • Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response
    • PMID:22424773
    • Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, et al. Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response. Mol Cell 2012; 46:212-25; PMID:22424773; http://dx.doi.org/10.1016/j.molcel.2012.01.026
    • (2012) Mol Cell , vol.46 , pp. 212-225
    • Beli, P.1    Lukashchuk, N.2    Wagner, S.A.3    Weinert, B.T.4    Olsen, J.V.5    Baskcomb, L.6
  • 12
    • 77956550868 scopus 로고    scopus 로고
    • Human SIRT6 promotes DNA end resection through CtIP deacetylation
    • PMID:20829486
    • Kaidi A, Weinert BT, Choudhary C, Jackson SP. Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science 2010; 329:1348-53; PMID:20829486; http://dx.doi.org/10.1126/science.1192049
    • (2010) Science , vol.329 , pp. 1348-1353
    • Kaidi, A.1    Weinert, B.T.2    Choudhary, C.3    Jackson, S.P.4
  • 13
    • 84864582469 scopus 로고    scopus 로고
    • FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response
    • PMID:22792074
    • Xie J, Peng M, Guillemette S, Quan S, Maniatis S, Wu Y, et al. FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response. PLoS Genet 2012; 8:e1002786; PMID:22792074; http://dx.doi.org/10.1371/journal.pgen. 1002786
    • (2012) PLoS Genet , vol.8
    • Xie, J.1    Peng, M.2    Guillemette, S.3    Quan, S.4    Maniatis, S.5    Wu, Y.6
  • 14
    • 12144286529 scopus 로고    scopus 로고
    • Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
    • PMID:15023334
    • Cohen HY, Lavu S, Bitterman KJ, Hekking B, Imahiyerobo TA, Miller C, et al. Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol Cell 2004; 13:627-38; PMID:15023334; http://dx.doi.org/10.1016/ S1097-2765(04)00094-2
    • (2004) Mol Cell , vol.13 , pp. 627-638
    • Cohen, H.Y.1    Lavu, S.2    Bitterman, K.J.3    Hekking, B.4    Imahiyerobo, T.A.5    Miller, C.6
  • 15
    • 27944499451 scopus 로고    scopus 로고
    • An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets
    • PMID:16273072
    • Schwartz D, Gygi SP. An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets. Nat Biotechnol 2005; 23:1391-8; PMID:16273072; http://dx.doi.org/10.1038/nbt1146
    • (2005) Nat Biotechnol , vol.23 , pp. 1391-1398
    • Schwartz, D.1    Gygi, S.P.2
  • 16
    • 55749111058 scopus 로고    scopus 로고
    • Linear motif atlas for phosphorylation-dependent signaling
    • PMID:18765831
    • Miller ML, Jensen LJ, Diella F, Jørgensen C, Tinti M, Li L, et al. Linear motif atlas for phosphorylation-dependent signaling. Sci Signal 2008; 1:ra2; PMID:18765831; http://dx.doi.org/10.1126/scisignal.1159433
    • (2008) Sci Signal , vol.1
    • Miller, M.L.1    Jensen, L.J.2    Diella, F.3    Jørgensen, C.4    Tinti, M.5    Li, L.6
  • 17
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • PMID:19131956
    • Huang W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009; 4:44-57; PMID:19131956; http://dx.doi.org/10.1038/nprot.2008.211
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 18
    • 0034069495 scopus 로고    scopus 로고
    • The Gene Ontology Consortium. Gene ontology: Tool for the unification of biology
    • PMID:10802651
    • Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, et al.; The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat Genet 2000; 25:25-9; PMID:10802651; http://dx.doi.org/10.1038/75556
    • (2000) Nat Genet , vol.25 , pp. 25-29
    • Ashburner, M.1    Ball, C.A.2    Blake, J.A.3    Botstein, D.4    Butler, H.5    Cherry, J.M.6
  • 19
    • 0030925920 scopus 로고    scopus 로고
    • Pfam: A comprehensive database of protein domain families based on seed alignments
    • PMID:9223186 3<405::AIDPROT10>3.0.CO;2-L
    • Sonnhammer EL, Eddy SR, Durbin R. Pfam: a comprehensive database of protein domain families based on seed alignments. Proteins 1997; 28:405-20; PMID:9223186; http://dx.doi.org/10.1002/(SICI)1097-0134(199707)28:3<405:: AIDPROT10> 3.0.CO;2-L
    • (1997) Proteins , vol.28 , pp. 405-420
    • Sonnhammer, E.L.1    Eddy, S.R.2    Durbin, R.3
  • 20
    • 55849149371 scopus 로고    scopus 로고
    • Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes
    • PMID:18794358
    • Ullah M, Pelletier N, Xiao L, Zhao SP, Wang K, Degerny C, et al. Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. Mol Cell Biol 2008; 28:6828-43; PMID:18794358; http://dx.doi.org/10.1128/MCB. 01297-08
    • (2008) Mol Cell Biol , vol.28 , pp. 6828-6843
    • Ullah, M.1    Pelletier, N.2    Xiao, L.3    Zhao, S.P.4    Wang, K.5    Degerny, C.6
  • 21
    • 66649120472 scopus 로고    scopus 로고
    • A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
    • PMID:19433796
    • Lee J, Kim DH, Lee S, Yang QH, Lee DK, Lee SK, et al. A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Proc Natl Acad Sci USA 2009; 106:8513-8; PMID:19433796; http://dx.doi.org/10.1073/pnas.0902873106
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8513-8518
    • Lee, J.1    Kim, D.H.2    Lee, S.3    Yang, Q.H.4    Lee, D.K.5    Lee, S.K.6
  • 22
    • 77956194960 scopus 로고    scopus 로고
    • Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function
    • PMID:20614009
    • Guendel I, Carpio L, Pedati C, Schwartz A, Teal C, Kashanchi F, et al. Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function. PLoS ONE 2010; 5:e11379; PMID:20614009; http://dx.doi.org/10.1371/journal.pone.0011379
    • (2010) PLoS ONE , vol.5
    • Guendel, I.1    Carpio, L.2    Pedati, C.3    Schwartz, A.4    Teal, C.5    Kashanchi, F.6
  • 23
    • 79851477462 scopus 로고    scopus 로고
    • Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis
    • PMID:21270520
    • Jurkin J, Zupkovitz G, Lagger S, Grausenburger R, Hagelkruys A, Kenner L, et al. Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis. Cell Cycle 2011; 10:406-12; PMID:21270520; http://dx.doi.org/10.4161/cc.10.3.14712
    • (2011) Cell Cycle , vol.10 , pp. 406-412
    • Jurkin, J.1    Zupkovitz, G.2    Lagger, S.3    Grausenburger, R.4    Hagelkruys, A.5    Kenner, L.6
  • 24
    • 33748451151 scopus 로고    scopus 로고
    • Anticancer activities of histone deacetylase inhibitors
    • PMID:16955068
    • Bolden JE, Peart MJ, Johnstone RW. Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Discov 2006; 5:769-84; PMID:16955068; http://dx.doi.org/10.1038/nrd2133
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 769-784
    • Bolden, J.E.1    Peart, M.J.2    Johnstone, R.W.3
  • 25
    • 78650012970 scopus 로고    scopus 로고
    • To selectivity and beyond
    • PMID:21139608
    • Mack GS. To selectivity and beyond. Nat Biotechnol 2010; 28:1259-66; PMID:21139608; http://dx.doi.org/10.1038/nbt.1724
    • (2010) Nat Biotechnol , vol.28 , pp. 1259-1266
    • Mack, G.S.1
  • 26
    • 79957993618 scopus 로고    scopus 로고
    • The class i HDAC inhibitor MGCD0103 induces cell cycle arrest and apoptosis in colon cancer initiating cells by upregulating Dickkopf-1 and noncanonical Wnt signaling
    • PMID:21317455
    • Sikandar S, Dizon D, Shen X, Li Z, Besterman J, Lipkin SM. The class I HDAC inhibitor MGCD0103 induces cell cycle arrest and apoptosis in colon cancer initiating cells by upregulating Dickkopf-1 and noncanonical Wnt signaling. Oncotarget 2010; 1:596-605; PMID:21317455
    • (2010) Oncotarget , vol.1 , pp. 596-605
    • Sikandar, S.1    Dizon, D.2    Shen, X.3    Li, Z.4    Besterman, J.5    Lipkin, S.M.6
  • 27
    • 79952270884 scopus 로고    scopus 로고
    • HDACs link the DNA damage response, processing of double-strand breaks and autophagy
    • PMID:21368826
    • Robert T, Vanoli F, Chiolo I, Shubassi G, Bernstein KA, Rothstein R, et al. HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature 2011; 471:74-9; PMID:21368826; http://dx.doi.org/10.1038/ nature09803
    • (2011) Nature , vol.471 , pp. 74-79
    • Robert, T.1    Vanoli, F.2    Chiolo, I.3    Shubassi, G.4    Bernstein, K.A.5    Rothstein, R.6
  • 28
    • 80052697814 scopus 로고    scopus 로고
    • The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks
    • PMID:21664912
    • Bekker-Jensen S, Mailand N. The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks. FEBS Lett 2011; 585:2914-9; PMID:21664912; http://dx.doi.org/10.1016/j.febslet.2011.05.056
    • (2011) FEBS Lett , vol.585 , pp. 2914-2919
    • Bekker-Jensen, S.1    Mailand, N.2
  • 29
    • 0026560833 scopus 로고
    • Doxorubicin inhibits human DNA topoisomerase i
    • PMID:1318169
    • Foglesong PD, Reckord C, Swink S. Doxorubicin inhibits human DNA topoisomerase I. Cancer Chemother Pharmacol 1992; 30:123-5; PMID:1318169; http://dx.doi.org/10.1007/BF00686403
    • (1992) Cancer Chemother Pharmacol , vol.30 , pp. 123-125
    • Foglesong, P.D.1    Reckord, C.2    Swink, S.3
  • 30
    • 0032568323 scopus 로고    scopus 로고
    • Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F
    • PMID:9569018
    • Hiyama H, Iavarone A, Reeves SA. Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F. Oncogene 1998; 16:1513-23; PMID:9569018; http://dx.doi.org/10.1038/sj.onc. 1201667
    • (1998) Oncogene , vol.16 , pp. 1513-1523
    • Hiyama, H.1    Iavarone, A.2    Reeves, S.A.3
  • 31
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • PMID:12118079
    • Ong SE, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, Pandey A, et al. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics 2002; 1:376-86; PMID:12118079; http://dx.doi.org/10.1074/mcp.M200025-MCP200
    • (2002) Mol Cell Proteomics , vol.1 , pp. 376-386
    • Ong, S.E.1    Blagoev, B.2    Kratchmarova, I.3    Kristensen, D.B.4    Steen, H.5    Pandey, A.6
  • 32
    • 79951889242 scopus 로고    scopus 로고
    • Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
    • PMID:21339330
    • Morselli E, Marĩo G, Bennetzen MV, Eisenberg T, Megalou E, Schroeder S, et al. Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome. J Cell Biol 2011; 192:615-29; PMID:21339330; http://dx.doi.org/10.1083/jcb.201008167
    • (2011) J Cell Biol , vol.192 , pp. 615-629
    • Morselli, E.1    Mariño, G.2    Bennetzen, M.V.3    Eisenberg, T.4    Megalou, E.5    Schroeder, S.6
  • 33
    • 57449099865 scopus 로고    scopus 로고
    • MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
    • PMID:19029910
    • Cox J, Mann M. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol 2008; 26:1367-72; PMID:19029910; http://dx.doi.org/10.1038/nbt.1511
    • (2008) Nat Biotechnol , vol.26 , pp. 1367-1372
    • Cox, J.1    Mann, M.2
  • 34
    • 79953701087 scopus 로고    scopus 로고
    • Andromeda: A peptide search engine integrated into the MaxQuant environment
    • PMID:21254760
    • Cox J, Neuhauser N, Michalski A, Scheltema RA, Olsen JV, Mann M. Andromeda: a peptide search engine integrated into the MaxQuant environment. J Proteome Res 2011; 10:1794-805; PMID:21254760; http://dx.doi.org/10.1021/ pr101065j
    • (2011) J Proteome Res , vol.10 , pp. 1794-1805
    • Cox, J.1    Neuhauser, N.2    Michalski, A.3    Scheltema, R.A.4    Olsen, J.V.5    Mann, M.6
  • 35
    • 33750456519 scopus 로고    scopus 로고
    • Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
    • PMID:17081983
    • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 2006; 127:635-48; PMID:17081983; http://dx.doi.org/10.1016/j. cell.2006.09.026
    • (2006) Cell , vol.127 , pp. 635-648
    • Olsen, J.V.1    Blagoev, B.2    Gnad, F.3    Macek, B.4    Kumar, C.5    Mortensen, P.6
  • 36
    • 33746429958 scopus 로고    scopus 로고
    • Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress
    • PMID:16885021
    • Mailand N, Bekker-Jensen S, Bartek J, Lukas J. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress. Mol Cell 2006; 23:307-18; PMID:16885021; http://dx.doi.org/10.1016/j. molcel.2006.06.016
    • (2006) Mol Cell , vol.23 , pp. 307-318
    • Mailand, N.1    Bekker-Jensen, S.2    Bartek, J.3    Lukas, J.4


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