Structure-activity relationships for bergenin analogues as β-secretase (BACE1) inhibitors

Journal of Oleo Science

Volumn 62, Issue 6, 2013, Pages 391-401

  Kashima, Yusei ^a   Miyazawa, Mitsuo ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

secretase; Antioxidant activity; Bergenin; Bergenin analogues; Structure activity relationships

Indexed keywords

ALZHEIMER'S DISEASE; ANTI-OXIDANT ACTIVITIES; BERGENIN; DOSE-DEPENDENT MANNER; INHIBITORY ACTIVITY; NATURALLY OCCURRING; SECRETASES; STRUCTURE ACTIVITY RELATIONSHIPS;

ANTIOXIDANT; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; BENZOIC ACID; BENZOPYRAN DERIVATIVE; BERGENIN; PROTEINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SECRETASE;

ALZHEIMER DISEASE; ARTICLE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ISOLATION AND PURIFICATION; MOLECULARLY TARGETED THERAPY; OXIDATIVE STRESS; PHYSIOLOGY; SAXIFRAGACEAE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANTIOXIDANTS; ASPARTIC ACID ENDOPEPTIDASES; BENZOIC ACID; BENZOPYRANS; DOSE-RESPONSE RELATIONSHIP, DRUG; MOLECULAR TARGETED THERAPY; OXIDATIVE STRESS; PROTEASE INHIBITORS; REACTIVE OXYGEN SPECIES; SAXIFRAGACEAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84878447270     PISSN: 13458957     EISSN: 13473352     Source Type: Journal    
DOI: 10.5650/jos.62.391     Document Type: Article

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