-
1
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
Jordan MA, Wilson L (2004) Microtubules as a target for anticancer drugs. Nat Rev Cancer 4(4):253-265.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
2
-
-
82755188164
-
What tubulin drugs tell us about microtubule structure and dynamics
-
Amos LA (2011) What tubulin drugs tell us about microtubule structure and dynamics. Semin Cell Dev Biol 22(9):916-926.
-
(2011)
Semin Cell Dev Biol
, vol.22
, Issue.9
, pp. 916-926
-
-
Amos, L.A.1
-
3
-
-
79953299183
-
Drugs that target dynamic microtubules: A new molecular perspective
-
Stanton RA, Gernert KM, Nettles JH, Aneja R (2011) Drugs that target dynamic microtubules: A new molecular perspective. Med Res Rev 31(3):443-481.
-
(2011)
Med Res Rev
, vol.31
, Issue.3
, pp. 443-481
-
-
Stanton, R.A.1
Gernert, K.M.2
Nettles, J.H.3
Aneja, R.4
-
5
-
-
84868514765
-
Microtubule stabilizing agents as potential treatment for Alzheimer's disease and related neurodegenerative tauopathies
-
Ballatore C, et al. (2012) Microtubule stabilizing agents as potential treatment for Alzheimer's disease and related neurodegenerative tauopathies. J Med Chem 55(21): 8979-8996.
-
(2012)
J Med Chem
, vol.55
, Issue.21
, pp. 8979-8996
-
-
Ballatore, C.1
-
6
-
-
77950608347
-
Microtubule targeting agents: From biophysics to proteomics
-
Calligaris D, et al. (2010) Microtubule targeting agents: From biophysics to proteomics. Cell Mol Life Sci 67(7):1089-1104.
-
(2010)
Cell Mol Life Sci
, vol.67
, Issue.7
, pp. 1089-1104
-
-
Calligaris, D.1
-
7
-
-
81855189480
-
The depolymerizing kinesins Kip3 (kinesin-8) and MCAK (kinesin-13) are catastrophe factors that destabilize microtubules by different mechanisms
-
Gardner MK, Zanic M, Gell C, Bormuth V, Howard J (2011) The depolymerizing kinesins Kip3 (kinesin-8) and MCAK (kinesin-13) are catastrophe factors that destabilize microtubules by different mechanisms. Cell 147(5):1092-1103.
-
(2011)
Cell
, vol.147
, Issue.5
, pp. 1092-1103
-
-
Gardner, M.K.1
Zanic, M.2
Gell, C.3
Bormuth, V.4
Howard, J.5
-
8
-
-
0029091976
-
Kinetics of microtubule catastrophe assessed by probabilistic analysis
-
Odde DJ, Cassimeris L, Buettner HM (1995) Kinetics of microtubule catastrophe assessed by probabilistic analysis. Biophys J 69(3):796-802.
-
(1995)
Biophys J
, vol.69
, Issue.3
, pp. 796-802
-
-
Odde, D.J.1
Cassimeris, L.2
Buettner, H.M.3
-
10
-
-
41149156427
-
Tracking the ends: A dynamic protein network controls the fate of microtubule tips
-
Akhmanova A, Steinmetz MO (2008) Tracking the ends: A dynamic protein network controls the fate of microtubule tips. Nat Rev Mol Cell Biol 9(4):309-322.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.4
, pp. 309-322
-
-
Akhmanova, A.1
Steinmetz, M.O.2
-
11
-
-
0037452096
-
Dynamics and mechanics of the microtubule plus end
-
Howard J, Hyman AA (2003) Dynamics and mechanics of the microtubule plus end. Nature 422(6933):753-758.
-
(2003)
Nature
, vol.422
, Issue.6933
, pp. 753-758
-
-
Howard, J.1
Hyman, A.A.2
-
12
-
-
84864319735
-
+ TIPs: SxIPping along microtubule ends
-
Kumar P, Wittmann T (2012) +TIPs: SxIPping along microtubule ends. Trends Cell Biol 22(8):418-428.
-
(2012)
Trends Cell Biol
, vol.22
, Issue.8
, pp. 418-428
-
-
Kumar, P.1
Wittmann, T.2
-
13
-
-
37249075604
-
Reconstitution of a microtubule plus-end tracking system in vitro
-
Bieling P, et al. (2007) Reconstitution of a microtubule plus-end tracking system in vitro. Nature 450(7172):1100-1105.
-
(2007)
Nature
, vol.450
, Issue.7172
, pp. 1100-1105
-
-
Bieling, P.1
-
14
-
-
84859736946
-
EBs recognize a nucleotide-dependent structural cap at growing microtubule ends
-
Maurer SP, Fourniol FJ, Bohner G, Moores CA, Surrey T (2012) EBs recognize a nucleotide-dependent structural cap at growing microtubule ends. Cell 149(2):371-382.
-
(2012)
Cell
, vol.149
, Issue.2
, pp. 371-382
-
-
Maurer, S.P.1
Fourniol, F.J.2
Bohner, G.3
Moores, C.A.4
Surrey, T.5
-
15
-
-
84866739601
-
Estimating the microtubule GTP cap size in vivo
-
Seetapun D, Castle BT, McIntyre AJ, Tran PT, Odde DJ (2012) Estimating the microtubule GTP cap size in vivo. Curr Biol 22(18):1681-1687.
-
(2012)
Curr Biol
, vol.22
, Issue.18
, pp. 1681-1687
-
-
Seetapun, D.1
Castle, B.T.2
McIntyre, A.J.3
Tran, P.T.4
Odde, D.J.5
-
16
-
-
64749115790
-
Mammalian end binding proteins control persistent microtubule growth
-
Komarova Y, et al. (2009) Mammalian end binding proteins control persistent microtubule growth. J Cell Biol 184(5):691-706.
-
(2009)
J Cell Biol
, vol.184
, Issue.5
, pp. 691-706
-
-
Komarova, Y.1
-
17
-
-
77957854052
-
In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends
-
Montenegro Gouveia S, et al. (2010) In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends. Curr Biol 20(19):1717-1722.
-
(2010)
Curr Biol
, vol.20
, Issue.19
, pp. 1717-1722
-
-
Montenegro Gouveia, S.1
-
18
-
-
77950964168
-
Accurate estimation of microtubule dynamics using kymographs and variable-rate particle filters
-
Smal I, Grigoriev I, Akhmanova A, Niessen WJ, Meijering E (2009) Accurate estimation of microtubule dynamics using kymographs and variable-rate particle filters. Conf Proc IEEE Eng Med Biol Soc 2009:1012-1015.
-
(2009)
Conf Proc IEEE Eng Med Biol Soc
, vol.2009
, pp. 1012-1015
-
-
Smal, I.1
Grigoriev, I.2
Akhmanova, A.3
Niessen, W.J.4
Meijering, E.5
-
19
-
-
0034665163
-
Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules
-
Ngan VK, et al. (2000) Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules. Cancer Res 60(18):5045-5051.
-
(2000)
Cancer Res
, vol.60
, Issue.18
, pp. 5045-5051
-
-
Ngan, V.K.1
-
20
-
-
0029923972
-
Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends
-
Panda D, Jordan MA, Chu KC, Wilson L (1996) Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends. J Biol Chem 271(47): 29807-29812.
-
(1996)
J Biol Chem
, vol.271
, Issue.47
, pp. 29807-29812
-
-
Panda, D.1
Jordan, M.A.2
Chu, K.C.3
Wilson, L.4
-
21
-
-
0027461876
-
Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine
-
Toso RJ, Jordan MA, Farrell KW, Matsumoto B, Wilson L (1993) Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine. Biochemistry 32(5):1285-1293.
-
(1993)
Biochemistry
, vol.32
, Issue.5
, pp. 1285-1293
-
-
Toso, R.J.1
Jordan, M.A.2
Farrell, K.W.3
Matsumoto, B.4
Wilson, L.5
-
22
-
-
0029155318
-
Kinetic stabilization of microtubule dynamics at steady state in vitro by substoichiometric concentrations of tubulincolchicine complex
-
Panda D, Daijo JE, Jordan MA, Wilson L (1995) Kinetic stabilization of microtubule dynamics at steady state in vitro by substoichiometric concentrations of tubulincolchicine complex. Biochemistry 34(31):9921-9929.
-
(1995)
Biochemistry
, vol.34
, Issue.31
, pp. 9921-9929
-
-
Panda, D.1
Daijo, J.E.2
Jordan, M.A.3
Wilson, L.4
-
23
-
-
42649104801
-
A unique mode of microtubule stabilization induced by peloruside A
-
Huzil JT, et al. (2008) A unique mode of microtubule stabilization induced by peloruside A. J Mol Biol 378(5):1016-1030.
-
(2008)
J Mol Biol
, vol.378
, Issue.5
, pp. 1016-1030
-
-
Huzil, J.T.1
-
24
-
-
84864152514
-
Epothilone B inhibits migration of glioblastoma cells by inducing microtubule catastrophes and affecting EB1 accumulation at microtubule plus ends
-
Pagano A, et al. (2012) Epothilone B inhibits migration of glioblastoma cells by inducing microtubule catastrophes and affecting EB1 accumulation at microtubule plus ends. Biochem Pharmacol 84(4):432-443.
-
(2012)
Biochem Pharmacol
, vol.84
, Issue.4
, pp. 432-443
-
-
Pagano, A.1
-
25
-
-
79959745449
-
Peloruside A inhibits microtubule dynamics in a breast cancer cell line MCF7
-
Chan A, Andreae PM, Northcote PT, Miller JH (2011) Peloruside A inhibits microtubule dynamics in a breast cancer cell line MCF7. Invest New Drugs 29(4):615-626.
-
(2011)
Invest New Drugs
, vol.29
, Issue.4
, pp. 615-626
-
-
Chan, A.1
Andreae, P.M.2
Northcote, P.T.3
Miller, J.H.4
-
26
-
-
59649117610
-
Carbendazim inhibits cancer cell proliferation by suppressing microtubule dynamics
-
Yenjerla M, Cox C, Wilson L, Jordan MA (2009) Carbendazim inhibits cancer cell proliferation by suppressing microtubule dynamics. J Pharmacol Exp Ther 328(2): 390-398.
-
(2009)
J Pharmacol Exp Ther
, vol.328
, Issue.2
, pp. 390-398
-
-
Yenjerla, M.1
Cox, C.2
Wilson, L.3
Jordan, M.A.4
-
27
-
-
33645533966
-
Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells
-
Pourroy B, et al. (2006) Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells. Cancer Res 66(6):3256-3263.
-
(2006)
Cancer Res
, vol.66
, Issue.6
, pp. 3256-3263
-
-
Pourroy, B.1
-
28
-
-
80052007210
-
Rapid microtubule self-assembly kinetics
-
Gardner MK, et al. (2011) Rapid microtubule self-assembly kinetics. Cell 146(4): 582-592.
-
(2011)
Cell
, vol.146
, Issue.4
, pp. 582-592
-
-
Gardner, M.K.1
-
29
-
-
69549122767
-
Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
-
Dorléans A, et al. (2009) Variations in the colchicine-binding domain provide insight into the structural switch of tubulin. Proc Natl Acad Sci USA 106(33):13775-13779.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.33
, pp. 13775-13779
-
-
Dorléans, A.1
-
30
-
-
19544393159
-
Structural basis for the regulation of tubulin by vinblastine
-
Gigant B, et al. (2005) Structural basis for the regulation of tubulin by vinblastine. Nature 435(7041):519-522.
-
(2005)
Nature
, vol.435
, Issue.7041
, pp. 519-522
-
-
Gigant, B.1
-
31
-
-
79952760876
-
GTPgammaS microtubules mimic the growing microtubule end structure recognised by end-binding proteins (EBs
-
Maurer SP, Bieling P, Cope J, Hoenger A, Surrey T (2011) GTPgammaS microtubules mimic the growing microtubule end structure recognised by end-binding proteins (EBs). Proc Natl Acad Sci USA 108(10):3988-3993.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.10
, pp. 3988-3993
-
-
Maurer, S.P.1
Bieling, P.2
Cope, J.3
Hoenger, A.4
Surrey, T.5
-
32
-
-
35348866321
-
Straight GDP-tubulin protofilaments form in the presence of taxol
-
Elie-Caille C, et al. (2007) Straight GDP-tubulin protofilaments form in the presence of taxol. Curr Biol 17(20):1765-1770.
-
(2007)
Curr Biol
, vol.17
, Issue.20
, pp. 1765-1770
-
-
Elie-Caille, C.1
-
33
-
-
84873090491
-
Molecular mechanism of action of microtubule-stabilizing anticancer agents
-
Prota AE, et al. (2013) Molecular mechanism of action of microtubule-stabilizing anticancer agents. Science 339(6119):587-590.
-
(2013)
Science
, vol.339
, Issue.6119
, pp. 587-590
-
-
Prota, A.E.1
-
34
-
-
0032520944
-
Low potency of taxol at microtubule minus ends: Implications for its antimitotic and therapeutic mechanism
-
Derry WB, Wilson L, Jordan MA (1998) Low potency of taxol at microtubule minus ends: Implications for its antimitotic and therapeutic mechanism. Cancer Res 58(6): 1177-1184.
-
(1998)
Cancer Res
, vol.58
, Issue.6
, pp. 1177-1184
-
-
Derry, W.B.1
Wilson, L.2
Jordan, M.A.3
-
35
-
-
0027360552
-
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
-
Jordan MA, Toso RJ, Thrower D, Wilson L (1993) Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci USA 90(20):9552-9556.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.20
, pp. 9552-9556
-
-
Jordan, M.A.1
Toso, R.J.2
Thrower, D.3
Wilson, L.4
-
36
-
-
0028908695
-
Substoichiometric binding of taxol suppresses microtubule dynamics
-
Derry WB, Wilson L, Jordan MA (1995) Substoichiometric binding of taxol suppresses microtubule dynamics. Biochemistry 34(7):2203-2211.
-
(1995)
Biochemistry
, vol.34
, Issue.7
, pp. 2203-2211
-
-
Derry, W.B.1
Wilson, L.2
Jordan, M.A.3
-
37
-
-
84857688962
-
Kinetochores and disease: Keeping microtubule dynamics in check!
-
Bakhoum SF, Compton DA (2012) Kinetochores and disease: Keeping microtubule dynamics in check!. Curr Opin Cell Biol 24(1):64-70.
-
(2012)
Curr Opin Cell Biol
, vol.24
, Issue.1
, pp. 64-70
-
-
Bakhoum, S.F.1
Compton, D.A.2
-
38
-
-
84873708996
-
Cadherin junctions and their cytoskeleton(s
-
Brieher WM, Yap AS (2013) Cadherin junctions and their cytoskeleton(s). Curr Opin Cell Biol 25(1):39-46.
-
(2013)
Curr Opin Cell Biol
, vol.25
, Issue.1
, pp. 39-46
-
-
Brieher, W.M.1
Yap, A.S.2
-
39
-
-
84866397855
-
Targeting and transport: How microtubules control focal adhesion dynamics
-
Stehbens S, Wittmann T (2012) Targeting and transport: How microtubules control focal adhesion dynamics. J Cell Biol 198(4):481-489.
-
(2012)
J Cell Biol
, vol.198
, Issue.4
, pp. 481-489
-
-
Stehbens, S.1
Wittmann, T.2
|