Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 22, 2013, Pages 8918-8923

  Rakowska, Paulina D ^a,b   Jiang, Haibo ^c   Ray, Santanu ^a   Pyne, Alice ^b   Lamarre, Baptiste ^a   Carr, Matthew ^d   Judge, Peter J ^e   Ravi, Jascindra ^a   Gerling, Ulla I M ^f   Koksch, Beate ^f   Martyna, Glenn J ^g   Hoogenboom, Bart W ^b   Watts, Anthony ^e   Crain, Jason ^a,d   Grovenor, Chris R M ^c   Ryadnova, Maxim G ^a,d  

^a NATIONAL PHYSICAL LABORATORY   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f FREIE UNIVERSITÄT BERLIN   (Germany)

^g IBM T J WATSON RESEARCH CENTER   (United States)

Author keywords

Antibiotics; De novo protein design; Innate host defense; Nanometrology; Nanoscopy

Indexed keywords

ANTIINFECTIVE AGENT; PHOSPHOLIPID;

AMINO ACID SEQUENCE; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; LINEAR DICHROISM; LIPID BILAYER; MASS SPECTROMETRY; NANOIMAGING; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TEMPERATURE;

ANTIBIOTICS; DE NOVO PROTEIN DESIGN; INNATE HOST DEFENSE; NANOMETROLOGY; NANOSCOPY;

AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; LIPID BILAYERS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICROSCOPY, ATOMIC FORCE; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; NANOTECHNOLOGY; PHOSPHOLIPIDS; PROTEIN ENGINEERING; SPECTROMETRY, MASS, SECONDARY ION;

EID: 84878432085     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222824110     Document Type: Article

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