Anticancer β-hairpin peptides: Membrane-induced folding triggers activityc

Journal of the American Chemical Society

Volumn 134, Issue 14, 2012, Pages 6210-6217

  Sinthuvanich, Chomdao ^a,b   Veiga, Ana Salomé ^a,c   Gupta, Kshitij ^d   Gaspar, Diana ^c   Blumenthal, Robert ^d   Schneider, Joel P ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

^c INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPHILICS; ANTICANCER ACTIVITIES; BREAST CARCINOMAS; CANCER CELL LINES; CANCER CELLS; CANCEROUS CELLS; CATIONIC ANTIMICROBIAL PEPTIDES; CD SPECTROSCOPY; CELL-BASED; HAIRPIN STRUCTURES; LIPID COMPOSITION; LUNG CARCINOMA; MECHANISM OF ACTION; MEMBRANE COMPOSITION; MEMBRANE DISRUPTION; NEGATIVELY CHARGED MEMBRANES;

CELL CULTURE; CELL MEMBRANES; CIRCULAR DICHROISM SPECTROSCOPY; ELECTRON MICROSCOPY; PEPTIDES;

MEMBRANES;

AMPHOPHILE; ANTINEOPLASTIC ANTIBIOTIC; LIPOSOME; POLYPEPTIDE ANTIBIOTIC AGENT; SVS 1 PEPTIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL DESTRUCTION; CELL MEMBRANE; CELL PROLIFERATION; CELL SURFACE; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; DRUG PURIFICATION; DRUG SELECTIVITY; ERYTHROCYTE; HEMOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LIPID COMPOSITION; MEMBRANE DAMAGE; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STATIC ELECTRICITY; UMBILICAL VEIN ENDOTHELIAL CELL;

ANTIMICROBIAL CATIONIC PEPTIDES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; CIRCULAR DICHROISM; HEMOLYSIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MEMBRANES; MICROSCOPY, ELECTRON; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PEPTIDES; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY;

EID: 84859562228     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja210569f     Document Type: Article

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