Melanin-concentrating hormone control of sleep-wake behavior

Sleep Medicine Reviews

Volumn 17, Issue 4, 2013, Pages 293-298

  Monti, Jaime M ^a   Torterolo, Pablo ^a   Lagos, Patricia ^a  

^a DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

Author keywords

MCHR1 receptor; Melanin concentrating hormone; REM sleep; Slow wave sleep; Wakefulness

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; GLUTAMIC ACID; MELANIN CONCENTRATING HORMONE; MONOAMINE; NEUROPEPTIDE; OREXIN;

ANIMAL EXPERIMENT; BRAIN REGION; CENTRAL NERVOUS SYSTEM; DORSAL RAPHE NUCLEUS; DRUG BINDING; DRUG MECHANISM; FOOD DEPRIVATION; FOREBRAIN; HYPOTHALAMUS; LIGHT DARK CYCLE; MOUSE; NERVE CELL; NONHUMAN; PONTINE NUCLEUS; RAT; REDUCTION; REM SLEEP; REVIEW; SLEEP WAKING CYCLE; SLOW WAVE SLEEP; WAKEFULNESS;

ANIMALS; BRAIN; CATS; HUMANS; HYPOTHALAMIC HORMONES; HYPOTHALAMUS; MELANINS; MICE; NEUROTRANSMITTER AGENTS; PITUITARY HORMONES; SLEEP; SLEEP STAGES; WAKEFULNESS;

EID: 84878414796     PISSN: 10870792     EISSN: 15322955     Source Type: Journal    
DOI: 10.1016/j.smrv.2012.10.002     Document Type: Review

References (55)

1. Pace-Schott E.F., Hobson J.A. Basic mechanisms of sleep: new evidence on the neuroanatomy and neuromodulation of the NREM-REM cycle. Neuropsychopharmacology - the fifth generation of progress 2002, 1859-1877. Lippincott: Williams and Wilkins, Philadelphia. D. Charney, C. Nemeroff (Eds.).
2. Jones B.E. Arousal systems. Front Biosci 2003, 8:438-451.
3. Monti J.M. Serotonin control of sleep-wake behavior. Sleep Med Rev 2011, 15:269-281.
4. Szymusiak R., Gvilia I., McGinty D. Hypothalamic control of sleep. Sleep Med 2007, 8:291-301.
5. Peyron C., Sapin E., Leger L., Luppi P.H., Fort P. Role of the melanin-concentrating hormone neuropeptide in sleep regulation. Peptides 2009, 30:2052-2059.
6. Torterolo P., Lagos P., Monti J.M. Melanin-concentrating hormone: a new sleep factor?. Front Neurol 2011, 2:2-12.
7. Vanni-Mercier G., Sakai K., Lin J.S., Jouvet M. Mapping of cholinoceptive brainstem structures responsible for the generation of paradoxical sleep in the cat. Arch Ital Biol 1989, 127:133-164.
8. Yamamoto K., Mamelak A.N., Quattrochi J.J., Hobson J.A. A cholinoceptive desynchronized sleep-induction zone in anterodorsal pontine tegmentum: locus of the sensitive region. Neuroscience 1990, 39:279-293.
9. Reinoso-Suárez F., de Andrés S., Rodrigo-Angulo M.L., Garzón M. Brain structures and mechanisms involved in the generation of REM sleep. Sleep Med Rev 2001, 5:63-77.
10. Hobson J.A., McCarley R.W., Wyzinski P.W. Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups. Science 1975, 189:55-58.
11. McCarley R.W. Neurobiology of REM and NREM sleep. Sleep Med 2007, 8:302-330.
12. Vaughan J.M., Fischer W.H., Hoeger C., Rivier J., Vale W. Characterization of melanin- concentrating hormone from rat hypothalamus. Endocrinology 1989, 125:1660-1665.
13. Bittencourt J., Celis M.E. Anatomy, function and regulation of neuropeptide EI (NEI). Peptides 2008, 29:1441-1450.
14. Sanchez M., Baker B.I., Celis M. Melanin-concentrating hormone (MCH) antagonizes the effects of alpha-MSH and neuropeptide E-I on grooming and locomotor activities in the rat. Peptides 1997, 18:393-396.
15. Lembo P.M., Grazzini E., Cao J., Hubatsch D.A., Pelletier M., Hoffert C., et al. The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein- coupled receptor. Nat Cell Biol 1999, 1:267-271.
16. An S., Cutler G., Zhao J.J., Huang S.G., Tian H., Li W., et al. Identification and characterization of a melanin-concentrating hormone receptor. Proc Natl Acad Sci USA 2001, 98:7576-7581.
17. Hawes B.E., Kil E., Green B., O'Neill K., Fried S., Graziano M.P. The melanin- concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways. Endocrinology 2000, 141:4524-4532.
18. Sailer A.W., Sano H., Zeng Z., McDonald T.P., Pan J., Pong S.S., et al. Identification and characterization of a second melanin-concentrating hormone receptor MCH-2R. Proc Natl Acad Sci USA 2001, 98:7564-7569.
19. Gao X.B., van den Pol A.N. Melanin-concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus. J Physiol 2001, 533(1):237-252.
20. Sekiya K., Ghatei M.A., Lacoumenta S., Burnet P.W., Zamir N., Burrin J.M., et al. The distribution of melanin-concentrating hormone-like immunoreactivity in the central nervous system of rat, guinea-pig, pig and man. Neuroscience 1988, 25:925-930.
21. Bittencourt J.C., Presse F., Arias C., Peto C., Vaughan J., Nahon J.L., et al. The melanin- concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. J Comp Neurol 1992, 319:218-245.
22. Bittencourt J.C., Elias C.F. Melanin-concentrating hormone and neuropeptide EI projections from the lateral hypothalamic area and zona incerta to the medial septal nucleus and spinal cord: a study using multiple neuronal tracers. Brain Res 1998, 805:1-19.
23. Elias C.F., Sita L.V., Zambon B.K., Oliveira E.R., Vasconcelos L.A.P., Bittencourt J.C. Melanin-concentrating hormone projections to areas involved in somatomotor responses. J Chem Neuroanat 2008, 35:188-201.
24. Hong E.Y., Yoon Y.S., Lee H.S. Differential distribution of melanin-concentrating hormone (MCH)- and hypocretin (Hcrt)-immunoreactive neurons projecting to the mesopontine cholinergic complex in the rat. Brain Res 2011, 1424:20-31.
25. Hervieu G.J., Cluderay J.E., Harrison D., Meakin J., Maycox P., Nasir S., et al. The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat. Eur J Neurosci 2000, 12:1194-1216.
26. Hassani O.K., Lee M.G., Jones B.E. Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep-wake cycle. Proc Natl Acad Sci USA 2009, 106:2418-2422.
27. Guyon A., Conductier G., Rovere C., Enfissi A., Nahon J.L. Melanin-concentrating hormone producing neurons: activities and modulations. Peptides 2009, 30:2031-2039.
28. Jo Y.H., Wiedl D., Role L.W. Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice. J Neurosci 2005, 25:11133-11144.
29. Huang H., van den Pol A.N. Rapid direct excitation and long-lasting enhancement of NMDA response by group 1 metabotropic glutamate receptor activation of hypothalamic melanin-concentrating hormone neurons. J Neurosci 2007, 27:11560-11572.
30. van den Pol A.N., Acuna-Goycolea C., Clark K.R., Ghosh P.K. Physiological properties of hypothalamic MCH neurons identified with selective expression of reporter gene after recombinant virus infection. Neuron 2004, 42:635-652.
31. Goutagny R., Luppi P.H., Salvert D., Gervasoni D., Fort P. GABAergic control of hypothalamic melanin-concentrating hormone-containing neurons across the sleep-waking cycle. Neuroreport 2005, 16:1069-1073.
32. Rao Y., Lu M., Ge F., Marsh D.J., Qian S., Wang A.H., et al. Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus. J Neurosci 2008, 28:9101-9110.
33. Modirrousta M., Mainville I., Jones B.E. Orexin and MCH neurons express c-Fos differently after sleep deprivation vs. recovery and bear different adrenergic receptors. Eur J Neurosci 2005, 21:2807-2816.
34. Collin M., Backberg M., Onnestam K., Meister B. 5-HT1A receptor immunoreactivity in hypothalamic neurons involved in body weight control. Neuroreport 2002, 13:945-951.
35. Bayer L., Risold P.Y., Griffond B., Fellmann D. Rat diencephalic neurons producing melanin-concentrating hormone are influenced by ascending cholinergic projections. Neuroscience 1999, 91:1087-1101.
36. Bayer L., Eggermann E., Serafin M., Grivel J., Machard D., Muhlethaler M., et al. Opposite effects of noradrenaline and acetylcholine upon hypocretin/orexin versus melanin concentrating hormone neurons in rat hypothalamic slices. Neuroscience 2005, 130:807-811.
37. Willie J.T., Sinton C.M., Maratos-Flier E., Yanagisawa M. Abnormal response of melanin-concentrating hormone deficient mice to fasting: hyperactivity and rapid eye movement sleep suppression. Neuroscience 2008, 156:819-829.
38. Adamantidis A., Salvert D., Goutagny R., Lakaye B., Gervasoni D., Grisar T., et al. Sleep architecture of the melanin-concentrating hormone receptor 1-knockout mice. Eur J Neurosci 2008, 27:1793-1800.
39. Ahnaou A., Dautzenberg F.M., Huysmans H., Steckler T., Drinkenburg W.H.I.M. Contribution of melanin-concentrating hormone (MCH) receptor to thermoregulation and sleep stabilization: evidence from MCH1(-/-) mice. Behav Brain Res 2011, 218:42-50.
40. Verret L., Goutagny R., Fort P., Cagnon L., Salvert D., Léger L., et al. A role of melanin- concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci 2003, 4:19-28.
41. Torterolo P., Sampogna S., Chase M.H. MCHergic projections to the nucleus pontis oralis participate in the control of active (REM) sleep. Brain Res 2009, 1268:76-87.
42. Lagos P., Torterolo P., Jantos H., Chase M.H., Monti J.M. Effects on sleep of melanin- concentrating hormone (MCH) microinjections into the dorsal raphe nucleus. Brain Res 2009, 1265:103-110.
43. Kilduff T.S., De Lecea L. Mapping of the mRNAs for the hypocretin/orexin and melanin-concentrating hormone receptors: networks of overlapping peptide systems. J Comp Neurol 2001, 435:1-5.
44. Lagos P., Torterolo P., Jantos H., Monti J.M. Immunoneutralization of melanin- concentrating hormone (MCH) in the dorsal raphe nucleus: effects on sleep and wakefulness. Brain Res 2011, 1269:112-118.
45. Lagos P., Monti J.M., Jantos H., Torterolo P. Microinjections of the melanin-concentrating hormone into the lateral basal forebrain increases REM sleep and reduces wakefulness in the rat. Life Sci 2012, 90:895-899.
46. Deurveilheur S., Semba K. Basal forebrain regulation of cortical activity and sleep-wake states: roles of cholinergic and non-cholinergic neurons. Sleep Biol Rhythms 2011, 9(Suppl. 1):65-70.
47. Henny P., Jones B.E. Vesicular glutamate (VGlut), GABA (VGAT), and acetylcholine (VACht) transporters in basal forebrain axon terminals innervating the lateral hypothalamus. J Comp Neurol 2006, 496:453-467.
48. Hassani O.K., Lee M.G., Henny P., Jones B.E. Discharge profiles of identified GABAergic in comparison to cholinergic and putative glutamatergic basal forebrain neurons across the sleep-wake cycle. J Neurosci 2009, 29:11828-11840.
49. Ahnaou A., Drinkenburg W.H.I.M., Bouwknecht J.A., Alcazar J., Steckler T., Dautzenberg F.M. Blocking melanin-concentrating hormone MCH1 receptor affects rat sleep-wake architecture. Eur J Pharmacol 2008, 579:177-188.
50. Monti J.M. Serotonin 5-HT2A receptor antagonists in the treatment of insomnia: present status and future prospects. Drugs Today 2011, 46:183-193.
51. Szymusiak R., Alam N., Steininger T.L., McGinty D. Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamus neurons in rats. Brain Res 1998, 803:178-188.
52. Trulson M.E., Jacobs B.L. Raphe unit activity in freely moving cats: correlation with level of behavioral arousal. Brain Res 1979, 163:135-150.
53. Aston-Jones G., Bloom F.E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci 1981, 1:876-886.
54. Vanni-Mercier G., Gigout S., Debilly G., Lin J.S. Waking selective neurons in the posterior hypothalamus and their response to histamine H3-receptor ligands: an electrophysiological study in freely moving cats. Behav Brain Res 2003, 144:227-241.
55. El Masari M., Sakai K., Jouvet M. Unitary characteristics of presumptive cholinergic tegmental neurons during the sleep-waking cycle in freely moving cats. Exp Brain Res 1989, 76:519-529.