Role of the melanin-concentrating hormone neuropeptide in sleep regulation

Peptides

Volumn 30, Issue 11, 2009, Pages 2052-2059

  Peyron, Christelle ^a   Sapin, Emilie ^a   Leger, Lucienne ^a   Luppi, Pierre Hervé ^a   Fort, Patrice ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Hypocretin; Hypothalamus; MCH; Memory; Narcolepsy; Orexin; Rapid eye movement sleep

Indexed keywords

MELANIN CONCENTRATING HORMONE; NEUROPEPTIDE;

ARTICLE; BEHAVIOR DISORDER; BRAIN CORTEX; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; BRAIN STEM; CATAPLEXY; COGNITION; DEMENTIA; DOPAMINERGIC TRANSMISSION; FACILITATION; GABAERGIC SYSTEM; HOMEOSTASIS; HORMONE ACTION; HUMAN; HYPERSOMNIA; HYPOTHALAMUS; MEMORY CONSOLIDATION; MONOAMINE NERVE CELL; MUSCLE ATONIA; NARCOLEPSY; NERVE CELL; NERVE CELL NETWORK; NERVE CELL STIMULATION; NERVE POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROANATOMY; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; NORADRENERGIC NERVE; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; REM SLEEP; SEROTONINERGIC NERVE CELL; SLEEP DISORDER; SLEEP INDUCTION; SLEEP PARAMETERS; SLEEP PATTERN; SLEEP WAKING CYCLE; SLOW WAVE SLEEP; SYMPTOM; SYNAPTIC TRANSMISSION; WAKEFULNESS;

ANIMALS; HUMANS; HYPOTHALAMIC HORMONES; HYPOTHALAMUS; MELANINS; MEMORY; MICE; MODELS, BIOLOGICAL; NARCOLEPSY; PITUITARY HORMONES; RATS; SLEEP; SLEEP, REM;

MUS MUSCULUS; RATTUS;

EID: 70349987623     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.07.022     Document Type: Article

References (88)

1. Adamantidis A., and de Lecea L. Physiological arousal: a role for hypothalamic systems. Cell Mol Life Sci 65 (2008) 1475-1488
2. Adamantidis A., Salvert D., Goutagny R., Lakaye B., Gervasoni D., Grisar T., et al. Sleep architecture of the melanin-concentrating hormone receptor 1-knockout mice. Eur J Neurosci 27 (2008) 1793-1800
3. Adamantidis A., Thomas E., Foidart A., Tyhon A., Coumans B., Minet A., et al. Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive deficits and alterations of NMDA receptor function. Eur J Neurosci 21 (2005) 2837-2844
4. Ahnaou A., Drinkenburg W.H., Bouwknecht J.A., Alcazar J., Steckler T., and Dautzenberg F.M. Blocking melanin-concentrating hormone MCH1 receptor affects rat sleep-wake architecture. Eur J Pharmacol 579 (2008) 177-188
5. Alam M.N., Gong H., Alam T., Jaganath R., McGinty D., and Szymusiak R. Sleep-waking discharge patterns of neurons recorded in the rat perifornical lateral hypothalamic area. J Physiol 538 (2002) 619-631
6. Alam M.N., Kumar S., Bashir T., Suntsova N., Methippara M.M., Szymusiak R., et al. GABA-mediated control of hypocretin- but not melanin-concentrating hormone-immunoreactive neurones during sleep in rats. J Physiol 563 (2005) 569-582
7. Backberg M., Collin M., Ovesjo M.L., and Meister B. Chemical coding of GABA(B) receptor-immunoreactive neurones in hypothalamic regions regulating body weight. J Neuroendocrinol 15 (2003) 1-14
8. Backberg M., Ultenius C., Fritschy J.M., and Meister B. Cellular localization of GABA receptor alpha subunit immunoreactivity in the rat hypothalamus: relationship with neurones containing orexigenic or anorexigenic peptides. J Neuroendocrinol 16 (2004) 589-604
9. Bayer L., Eggermann E., Serafin M., Grivel J., Machard D., Muhlethaler M., et al. Opposite effects of noradrenaline and acetylcholine upon hypocretin/orexin versus melanin concentrating hormone neurons in rat hypothalamic slices. Neuroscience 130 (2005) 807-811
10. Bayer L., Risold P.Y., Griffond B., and Fellmann D. Rat diencephalic neurons producing melanin-concentrating hormone are influenced by ascending cholinergic projections. Neuroscience 91 (1999) 1087-1101
11. Bittencourt J.C., Presse F., Arias C., Peto C., Vaughan J., Nahon J.L., et al. The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. J Comp Neurol 319 (1992) 218-245
12. Blouin A.M., Thannickal T.C., Worley P.F., Baraban J.M., Reti I.M., and Siegel J.M. Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy. Neurology 65 (2005) 1189-1192
13. Boeve B.F., Silber M.H., Saper C.B., Ferman T.J., Dickson D.W., Parisi J.E., et al. Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain 130 (2007) 2770-2788
14. Boissard R., Fort P., Gervasoni D., Barbagli B., and Luppi P.H. Localization of the GABAergic and non-GABAergic neurons projecting to the sublaterodorsal nucleus and potentially gating paradoxical sleep onset. Eur J Neurosci 18 (2003) 1627-1639
15. Boissard R., Gervasoni D., Schmidt M.H., Barbagli B., Fort P., and Luppi P.H. The rat ponto-medullary network responsible for paradoxical sleep onset and maintenance: a combined microinjection and functional neuroanatomical study. Eur J Neurosci 16 (2002) 1959-1973
16. Borowsky B., Durkin M.M., Ogozalek K., Marzabadi M.R., DeLeon J., Lagu B., et al. Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist. Nat Med 8 (2002) 825-830
17. Clement O, Sapin E, Berod A, Gervasoni D, Fort P, Luppi PH. Evidence that neurons of the sublaterodorsal tegmental nucleus triggering paradoxical (REM) sleep are glutamatergic. In: 39th annual meeting of the Society for Neuroscience; 2009.
18. Collin M., Backberg M., Onnestam K., and Meister B. 5-HT1A receptor immunoreactivity in hypothalamic neurons involved in body weight control. Neuroreport 13 (2002) 945-951
19. Crocker A., Espana R.A., Papadopoulou M., Saper C.B., Faraco J., Sakurai T., et al. Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology 65 (2005) 1184-1188
20. Cvetkovic V., Brischoux F., Griffond B., Bernard G., Jacquemard C., Fellmann D., et al. Evidence of melanin-concentrating hormone-containing neurons supplying both cortical and neuroendocrine projections. Neuroscience 116 (2003) 31-35
21. Dauvilliers Y., Arnulf I., and Mignot E. Narcolepsy with cataplexy. Lancet 369 (2007) 499-511
22. Eggermann E., Bayer L., Serafin M., Saint-Mleux B., Bernheim L., Machard D., et al. The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization. J Neurosci 23 (2003) 1557-1562
23. Elias C.F., Lee C.E., Kelly J.F., Ahima R.S., Kuhar M., Saper C.B., et al. Characterization of CART neurons in the rat and human hypothalamus. J Comp Neurol 432 (2001) 1-19
24. Estabrooke I.V., McCarthy M.T., Ko E., Chou T.C., Chemelli R.M., Yanagisawa M., et al. Fos expression in orexin neurons varies with behavioral state. J Neurosci 21 (2001) 1656-1662
25. Fort P., Bassetti C.L., and Luppi P.H. Alternating vigilance states: new insights regarding neuronal networks and mechanisms. Eur J Neurosci 29 (2009) 1741-1753
26. Fort P., Salvert D., Hanriot L., Jego S., Shimizu H., Hashimoto K., et al. The satiety molecule nesfatin-1 is co-expressed with melanin concentrating hormone in tuberal hypothalamic neurons of the rat. Neuroscience 155 (2008) 174-181
27. Gallopin T., Fort P., Eggermann E., Cauli B., Luppi P.H., Rossier J., et al. Identification of sleep-promoting neurons in vitro. Nature 404 (2000) 992-995
28. Gao X.B., Ghosh P.K., and van den Pol A.N. Neurons synthesizing melanin-concentrating hormone identified by selective reporter gene expression after transfection in vitro: transmitter responses. J Neurophysiol 90 (2003) 3978-3985
29. Gao X.B., and van den Pol A.N. Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus. J Physiol 533 (2001) 237-252
30. Gervasoni D., Darracq L., Fort P., Souliere F., Chouvet G., and Luppi P.H. Electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by GABA during sleep. Eur J Neurosci 10 (1998) 964-970
31. Gervasoni D., Peyron C., Rampon C., Barbagli B., Chouvet G., Urbain N., et al. Role and origin of the GABAergic innervation of dorsal raphe serotonergic neurons. J Neurosci 20 (2000) 4217-4225
32. Goutagny R., Luppi P.H., Salvert D., Gervasoni D., and Fort P. GABAergic control of hypothalamic melanin-concentrating hormone-containing neurons across the sleep-waking cycle. Neuroreport 16 (2005) 1069-1073
33. Goutagny R., Luppi P.H., Salvert D., Lapray D., Gervasoni D., and Fort P. Role of the dorsal paragigantocellular reticular nucleus in paradoxical (rapid eye movement) sleep generation: a combined electrophysiological and anatomical study in the rat. Neuroscience 152 (2008) 849-857
34. Guan J.L., Uehara K., Lu S., Wang Q.P., Funahashi H., Sakurai T., et al. Reciprocal synaptic relationships between orexin- and melanin-concentrating hormone-containing neurons in the rat lateral hypothalamus: a novel circuit implicated in feeding regulation. Int J Obes Relat Metab Disord 26 (2002) 1523-1532
35. Hanriot L., Camargo N., Courau A.C., Leger L., Luppi P.H., and Peyron C. Characterization of the melanin-concentrating hormone neurons activated during paradoxical sleep hypersomnia in rats. J Comp Neurol 505 (2007) 147-157
36. Hassani O.K., Lee M.G., and Jones B.E. Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep-wake cycle. Proc Natl Acad Sci USA 106 (2009) 2418-2422
37. Hennevin E., Huetz C., and Edeline J.M. Neural representations during sleep: from sensory processing to memory traces. Neurobiol Learn Mem 87 (2007) 416-440
38. Hervieu G.J., Cluderay J.E., Harrison D., Meakin J., Maycox P., Nasir S., et al. The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat. Eur J Neurosci 12 (2000) 1194-1216
39. Jones B.E. From waking to sleeping: neuronal and chemical substrates. Trends Pharmacol Sci 26 (2005) 578-586
40. Jouvet M. Recherches sur les structures nerveuses et les mécanismes responsables des différentes phases du sommeil physiologique. Arch Ital Biol 100 (1962) 125-206
41. Jouvet M., Jeannerod M., and Delorme F. Organization of the system responsible for phase activity during paradoxal sleep. C R Seances Soc Biol Fil 159 (1965) 1599-1604
42. Jouvet M., and Michel F. Corrélations électromyographiques du sommeil chez le chat décortiqué et mésencéphalique chronique. CR Soc Biol 153 (1959) 422-425
43. Kovacs K.J. Measurement of immediate-early gene activation-c-fos and beyond. J Neuroendocrinol 20 (2008) 665-672
44. Koyama Y., Takahashi K., Kodama T., and Kayama Y. State-dependent activity of neurons in the perifornical hypothalamic area during sleep and waking. Neuroscience 119 (2003) 1209-1219
45. Lagos P., Torterolo P., Jantos H., Chase M.H., and Monti J.M. Effects on sleep of melanin-concentrating hormone (MCH) microinjections into the dorsal raphe nucleus. Brain Res 1265 (2009) 103-110
46. Lee M.G., Hassani O.K., and Jones B.E. Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle. J Neurosci 25 (2005) 6716-6720
47. Lin J.S., Sakai K., Vanni-Mercier G., and Jouvet M. A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscimol in freely moving cats. Brain Res 479 (1989) 225-240
48. Lu J., Sherman D., Devor M., and Saper C.B. A putative flip-flop switch for control of REM sleep. Nature 441 (2006) 589-594
49. Luppi P.H., Gervasoni D., Verret L., Goutagny R., Peyron C., Salvert D., et al. Paradoxical (REM) sleep genesis: the switch from an aminergic-cholinergic to a GABAergic-glutamatergic hypothesis. J Physiol Paris 100 (2006) 271-283
50. Marshall L., and Born J. The contribution of sleep to hippocampus-dependent memory consolidation. Trends Cogn Sci 11 (2007) 442-450
51. Mileykovskiy B.Y., Kiyashchenko L.I., and Siegel J.M. Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron 46 (2005) 787-798
52. Modirrousta M., Mainville L., and Jones B.E. Orexin and MCH neurons express c-Fos differently after sleep deprivation vs. recovery and bear different adrenergic receptors. Eur J Neurosci 21 (2005) 2807-2816
53. Monzon M.E., de Souza M.M., Izquierdo L.A., Izquierdo I., Barros D.M., and de Barioglio S.R. Melanin-concentrating hormone (MCH) modifies memory retention in rats. Peptides 20 (1999) 1517-1519
54. Moragues N., Ciofi P., Lafon P., Tramu G., and Garret M. GABAA receptor epsilon subunit expression in identified peptidergic neurons of the rat hypothalamus. Brain Res 967 (2003) 285-289
55. Nahon J.L., Presse F., Bittencourt J.C., Sawchenko P.E., and Vale W. The rat melanin-concentrating hormone messenger ribonucleic acid encodes multiple putative neuropeptides coexpressed in the dorsolateral hypothalamus. Endocrinology 125 (1989) 2056-2065
56. Nauta W.J. Hypothalamic regulation of sleep in rats. Experimental study. J Neurophysiol 9 (1946) 285-316
57. Nishino S., and Mignot E. Pharmacological aspects of human and canine narcolepsy. Prog Neurobiol 52 (1997) 27-78
58. Pachoud B, Adamantidis A, Lakaye B, Luppi P, Grisar T, Salin P. Multiple actions of the melanin-concentrating hormone receptor 1 on rodent hippocampal synaptic function. In: 36th annual meeting of the Society for Neuroscience; 2006.
59. Peyron C., Faraco J., Rogers W., Ripley B., Overeem S., Charnay Y., et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 6 (2000) 991-997
60. Rao Y., Lu M., Ge F., Marsh D.J., Qian S., Wang A.H., et al. Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus. J Neurosci 28 (2008) 9101-9110
61. Saito Y., Cheng M., Leslie F.M., and Civelli O. Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain. J Comp Neurol 435 (2001) 26-40
62. Sapin E., Lapray D., Berod A., Goutagny R., Leger L., Ravassard P., et al. Localization of the brainstem GABAergic neurons controlling paradoxical (REM) sleep. PLoS ONE 4 (2009) e4272
63. Sapin E, Leger L, Berod A, Herman PA, Luppi PH, Peyron C. Localization of hypothalamic GABAergic neurons implicated in paradoxical (REM) sleep regulation and their relationship with MCH neurons. In: 39th annual meeting of the Society for Neuroscience; 2009.
64. 2A receptor agonist. Behav Brain Res 170 (2006) 277-286
65. Schmidt M.H., Sakai K., Valatx J.L., and Jouvet M. The effects of spinal or mesencephalic transections on sleep-related erections and ex-copula penile reflexes in the rat. Sleep 22 (1999) 409-418
66. Sherin J.E., Shiromani P.J., McCarley R.W., and Saper C.B. Activation of ventrolateral preoptic neurons during sleep. Science 271 (1996) 216-219
67. Shimada M., Tritos N.A., Lowell B.B., Flier J.S., and Maratos-Flier E. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396 (1998) 670-674
68. Smith D.G., Tzavara E.T., Shaw J., Luecke S., Wade M., Davis R., et al. Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice. J Neurosci 25 (2005) 914-922
69. Stickgold R., and Walker M.P. Sleep-dependent memory consolidation and reconsolidation. Sleep Med 8 (2007) 331-343
70. Suntsova N., Szymusiak R., Alam M.N., Guzman-Marin R., and McGinty D. Sleep-waking discharge patterns of median preoptic nucleus neurons in rats. J Physiol 543 (2002) 665-677
71. Szymusiak R., Alam N., Steininger T.L., and McGinty D. Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats. Brain Res 803 (1998) 178-188
72. Takahashi K., Lin J.S., and Sakai K. Neuronal activity of histaminergic tuberomammillary neurons during wake-sleep states in the mouse. J Neurosci 26 (2006) 10292-10298
73. Takahashi K., Lin J.S., and Sakai K. Neuronal activity of orexin and non-orexin waking-active neurons during wake-sleep states in the mouse. Neuroscience 153 (2008) 860-870
74. Tan C.P., Sano H., Iwaasa H., Pan J., Sailer A.W., Hreniuk D.L., et al. Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression. Genomics 79 (2002) 785-792
75. Thannickal T.C., Lai Y.Y., and Siegel J.M. Hypocretin (orexin) cell loss in Parkinson's disease. Brain 130 (2007) 1586-1595
76. Thannickal T.C., Moore R.Y., Nienhuis R., Ramanathan L., Gulyani S., Aldrich M., et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron 27 (2000) 469-474
77. Torterolo P., Sampogna S., Morales F.R., and Chase M.H. MCH-containing neurons in the hypothalamus of the cat: searching for a role in the control of sleep and wakefulness. Brain Res 1119 (2006) 101-114
78. Toumaniantz G., Bittencourt J.C., and Nahon J.L. The rat melanin-concentrating hormone gene encodes an additional putative protein in a different reading frame. Endocrinology 137 (1996) 4518-4521
79. van den Pol A.N., Acuna-Goycolea C., Clark K.R., and Ghosh P.K. Physiological properties of hypothalamic MCH neurons identified with selective expression of reporter gene after recombinant virus infection. Neuron 42 (2004) 635-652
80. Vanni-Mercier G., Sakai K., Lin J.S., and Jouvet M. Mapping of cholinoceptive brainstem structures responsible for the generation of paradoxical sleep in the cat. Arch Ital Biol 127 (1989) 133-164
81. Varas M., Perez M., Ramirez O., and de Barioglio S.R. Melanin concentrating hormone increase hippocampal synaptic transmission in the rat. Peptides 23 (2002) 151-155
82. Varas M.M., Perez M.F., Ramirez O.A., and de Barioglio S.R. Increased susceptibility to LTP generation and changes in NMDA-NR1 and -NR2B subunits mRNA expression in rat hippocampus after MCH administration. Peptides 24 (2003) 1403-1411
83. Verret L., Fort P., Gervasoni D., Leger L., and Luppi P.H. Localization of the neurons active during paradoxical (REM) sleep and projecting to the locus coeruleus noradrenergic neurons in the rat. J Comp Neurol 495 (2006) 573-586
84. Verret L., Goutagny R., Fort P., Cagnon L., Salvert D., Leger L., et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci 4 (2003) 19
85. Volgin D.V., Swan J., and Kubin L. Single-cell RT-PCR gene expression profiling of acutely dissociated and immunocytochemically identified central neurons. J Neurosci Meth 136 (2004) 229-236
86. Willie J.T., Sinton C.M., Maratos-Flier E., and Yanagisawa M. Abnormal response of melanin-concentrating hormone deficient mice to fasting: hyperactivity and rapid eye movement sleep suppression. Neuroscience 156 (2008) 819-829
87. Yoshida K., McCormack S., Espana R.A., Crocker A., and Scammell T.E. Afferents to the orexin neurons of the rat brain. J Comp Neurol 494 (2006) 845-861
88. Yoshida Y., Fujiki N., Nakajima T., Ripley B., Matsumura H., Yoneda H., et al. Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities. Eur J Neurosci 14 (2001) 1075-1081