Ellagic acid checks lymphoma promotion via regulation of PKC signaling pathway

Molecular Biology Reports

Volumn 40, Issue 2, 2013, Pages 1417-1428

  Mishra, Sudha ^a   Vinayak, Manjula ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

c Myc; Dalton's lymphoma; Ellagic acid; NF kB; PKC; TGF 1

Indexed keywords

ELLAGIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOENZYME; MYC PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C GAMMA; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASCITES; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; LIFESPAN; LIPID PEROXIDATION; LYMPHOMA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; ELLAGIC ACID; GENE EXPRESSION REGULATION; HUMANS; ISOENZYMES; LYMPHOMA; MALONDIALDEHYDE; MICE; MICE, INBRED AKR; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NF-KAPPA B; OXIDATIVE STRESS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-MYC; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR CELLS, CULTURED;

MUS;

EID: 84878369551     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2185-8     Document Type: Article

References (51)

1. Milligan SA, Owens MW, Grisham MB (1998) Differential regulation of extracellular signal-regulated kinase and nuclear factor-kappa B signal transduction pathways by hydrogen peroxide and tumor necrosis factor. Arch Biochem Biophys 352:255-262
2. Abate C, Patel L, Rauscher FJ, Curran T (1990) Redox regulation of Fos and Jun DNA -binding activity in vitro. Science 249:1157-1161
3. Jussi K, Vesa A, Juha P (2006) Protein kinase C (PKC) family in cancer progression. Cancer Lett 235:1-10
4. Black JD (2000) Protein Kinase C mediated regulation of the cell cycle. Front Biosci 5:406-423
5. Gopalakrishna R, Gundimeda U (2002) Antioxidant regulation of protein kinase C in cancer prevention. J Nutr 132:3819S-3823S
6. Saijo K, Mecklenbräuker I, Santana A, Leitger M, Schmedt C, Tarakhovsky A (2002) Protein kinase Cβ controls nuclear factor κB activation in B cells through selective regulation of the IκB kinase α. J Exp Med 195:1647-1652
7. Trushin SA, Pennington KN, Algeciras-Schimnich A, Paya CV (1999) Protein kinase C and calcineurin synergize to activate IkB kinase and NF-kB in T lymphocytes. J Biol Chem 274:22923-22931
8. Philipp JJ, Ruland J (2007) Aberrant NF-kB signaling in lymphoma: mechanisms, consequences, and therapeutic implications. Blood 109:2700-2707
9. Anderson MT, Staal FJ, Gitler C, Herzenberg LA, Herzenberg LA (1994) Separation of oxidant-initiated and redox regulated steps in the NF-kB signal transduction pathway. Proc Natl Acad Sci USA 91:11527-11531
10. Carballo M (1999) Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation of in human lymphocytes. J Biol Chem 274:17580-17586
11. Flohe L, Brigelius-Flohé R, Saliou C, Traber MG, Packer L (1997) Redox regulation of NF-kB activation. Free Radic Biol Med 22:1115-1126
12. Dorai T, Agrawal BB (2004) Role of chemopreventive agents in cancer therapy. Cancer Lett 215:129-140
13. Singh RP, Dhanalakshmi S, Agarwal R (2002) Phytochemicals as cell cycle modulators. Cell Cycle 1:156-161
14. Edderkaoui M et al (2008) Ellagic acid induces apoptosis through inhibition of nuclear factor kappa B in pancreatic cancer cells. World J Gastroenterol 14(23):3672-3680
15. Li TM, Chen GW, Su CC, Lin JG, Yeh CC, Cheng KC et al (2005) Ellagic acid indu p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells. Anticancer Res 25(2A):971-979
16. Larrosa M, Tomás-Barberán FA, Espín JC (2006) The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway. J Nutr Biochem 17:611-625
17. Barre B, Perkins ND (2007) A cell cycle regulatory network controlling NF-kB subunit activity and function. EMBO J 26:4841-4855
18. Adhikary S, Eilers M (2005) Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 6(8):635-645
19. Derynck R, Akhurst RJ, Balmain A (2001) TGF-β signaling in tumor suppression and cancer progression. Nat Genet 29:117-129
20. Sebestyena A, Barna G, Katalin N, Judit J, Sandor P, Eszter K (2005) Smad signal and TGF-β induced apoptosis in human lymphoma cells. Cytokine 30:228-235
21. Marilyn LG, Long DD, Goodwin SM, Lee C (1997) Transforming growth factor-b1 inhibits membrane association of protein kinase Ca in a human prostate cancer cell line. Endocrinology 138:4657-4664
22. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358
23. Sharma R, Vinayak M (2011) α-Tocopherol attenuates NF-κB activation and proinflammatory cytokine IL-6 secretion in cancer bearing mice. Biosci Rep 31:421-428
24. Mishra S, Vinayak M (2011) Anti-carcinogenic action of ellagic acid mediated via modulation of oxidative stress regulated genes in Dalton lymphoma bearing mice. Leuk Lymphoma 52(11):2155-2161
25. Sladowski D, Lebovitz RM, Roeder RD (1993) An improved MTT assay. J Immunol Methods 157:203-207
26. Dignam JD, Lebovitz RM, Roeder RD (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489
27. Liu SF, Ye X, Malik AB (1999) Inhibition of NF-kB activation by pyrrolidine dithiocarbamate prevents in vivo expression of proinflammatory genes. Circulation 12:1330-1337
28. Otamiri T, Sjodah R (1989) Increased lipid peroxidation in malignant tissues of patients with colorectal cancer. Cancer 61:122-125
29. Ahmed MI, Fayed ST, Hossein H, Tash FM (1999) Lipid peroxidation and antioxidant status in human cervical carcinoma. Dis Markers 15:283-291
30. Diplock AT, Rice-Evans AC, Burton RH (1994) Is there a significant role for lipid peroxidation in causation of malignancy and for antioxidants in cancer prevention? Cancer Res 54:19525-19526
31. Trang-Tiau Wu, Yi Hsien, Yih-Shou H, Jer-Yuh Liu (2008) Reduction of PKCα decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma. J Cell Biochem 103:9-20
32. Lønne Gry Kalstad, Cornmark L, Zahirovic IO, Landberg G, Jirström K, Larsson C (2010) PKCα expression is a marker for breast cancer aggressiveness. Mol Cancer 9:76
33. Graff JR et al (2005) The protein kinase C-β selective inhibitor, enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts. Cancer Res 65:7462-7469
34. Shipp MA, Ross KN, Tamayo P, Weng AP, Kutok JL, Aguiar RC et al (2002) Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nat Med 8:68-74
35. Gokmen-Polar Y, McNulty AM, Hanna KR, Konicek BW, Lynch RL, Bailey SN et al (2001) Elevated protein kinase C β II is an early promotive event in colon carcinogenesis. Cancer Res 61:1375-1381
36. Teicher BA, Menon K, Alvarez E, Liu P, Shih C, Faul MM (2001) Antiangiogenic and antitumor effects of a protein kinase C-β inhibitor in human hepatocellular and gastric cancer xenografts. In Vivo 15:185-193
37. Kamimura K, Hojoand H, Abe M (2004) Characterization of expression of protein kinase C isozymes in human B-cell lymphoma: relationship between its expression and prognosis. Pathol Int 54:224-230
38. Dorota G, Szeker K, Galfi P, Csordas A, Hofmann J (2010) Protein kinase C in colon cancer cells: expression, Thr514 phosphorylation and sensitivity to butyrate-mediated up regulation as related to the degree of differentiation. Johann Hofmanna Chem Biol Interact 185:25-32
39. Melanie K, Gudrun P, Kamal KB, Frank DB, Doris M (2007) Apple polyphenols affect protein kinase C activity and the onset of apoptosis in human colon carcinoma Cells. J Agric Food Chem 55:4999-5006
40. Alvaro V et al (1992) Protein kinase C activity and expression in normal and adenomatous human pituitaries. Int J Cancer 50:724-730
41. Kusunoki M, Sakanoue Y, Hatada T, Yanagi H, Yamamura T, Utsunomiya J (1992) Protein kinase C activity in human colonic adenoma and colorectal carcinoma. Cancer 69:24-30
42. Chung CH, Chung Joel S, Parker Kim Ely (2006) Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kB signaling as characteristics of a high-risk head and neck squamous cell carcinoma. Cancer Res 66:8210-8218
43. Hinz M, Lemke P, Anagnostopoulos I, Hacker C, Krappmann D, Mathas S (2002) Nuclear factor kB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance and link to constitutive signal transducer and activator of transcription activity. J Exp Med 196:605-617
44. Van Laere SJ, Vander Auwera I, Vanden Eynden GG, Elst HJ, Weyler J, Harris AL et al (2006) Nuclear factor-kappa B signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappa B DNA binding. Clin Cancer Res 12:3249-3256
45. Kim SO, Chun KS, Kundu JK, Surh YJ (2004) Inhibitory effects of [6]-gingerol on PMA-induced COX-2 expression and activation of NF-kB and p38 MAPK in mouse skin. Biofactors 21(1-4):27-31
46. Takada Y, Murakami A, Aggarwal BB (2005) Zerumbone abolishes NF-kappa B and Ik Bα kinase activation leading to suppression of antiapoptotic and metastatic gene expression, up regulation of apoptosis, and down regulation of invasion. Oncogene 24(46):6957-6969
47. Villalba M, Kasibhatla S, Genestier L, Mahboubi A, Green DR, Altman A (1999) Protein kinase C θ cooperates with calcineurin to induce Fas ligand expression during activation- induced T cell death. J Immunol 163:5813-5819
48. Zajac-Kaye M (2001) Myc oncogene: a key component in cell cycle regulation and its implication for lung cancer. Lung Cancer 34:S43-S46
49. Lori M, Donald EM (1997) Protein Kinase C is not necessary for transforming growth factor beta-induced growth-arrest in leukemia cell lines. Leuk Res 21:403-410
50. Marilyn LG, Yu G, Yu D, Zhu M (2010) PKCα-induced drug resistance in pancreatic cancer cells is associated with transforming growth factor-b1. J Exp Clin Cancer Res 29:104
51. Perlino E, Loverro G, Maiorano E, Giannini T, Cazzolla A, Napoli A et al (1998) Down regulated expression of transforming growth factor βI mRNA in endometrial carcinoma. Br J Cancer 77(8):1260-1266