Transforming growth factor-β1 inhibits membrane association of protein kinase Cα in a human prostate cancer cell line, PC3

Endocrinology

Volumn 138, Issue 11, 1997, Pages 4657-4664

  Lamm, Marilyn L G ^a   Long, Denise D ^a   Goodwin, Shannon M ^a   Lee, Chung ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE C; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOGENESIS; PRIORITY JOURNAL; PROSTATE CANCER; SIGNAL TRANSDUCTION;

EID: 0030812545     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.11.5531     Document Type: Article

References (54)

1. Roberts AB, Sporn MB 1990 The transforming growth factors-β. In: Sporn MB, Roberts AB, eds. Handbook of experimental pharmacology. Peptide growth factors and their receptors. Springer-Verlag, Heidelgerg FRG; vol 95:419-472
2. Massague J, Cheifetz S, Laiho M, Ralph DA, Weis FMB, Zentella A 1992 Transforming growth factor-β. Cancer Surv 12:81-103
3. Filmus J, Kerbel RS 1993 Development of resistance mechanisms to the growth-inhibitory effects of transforming growth factor-beta during tumor progression. Curr Opin Oncol 5:123-129
4. Wrana JL, Attisano L, Carcamo J, Zentella A, Doody J, Laiho M, Wang X-F, Massague J 1992 TGFβ signals through a heteromeric protein kinase receptor complex. Cell 71:1003-1014
5. Franzen P, ten Dijke P, Ichijo H, Yamashita H, Schulz P, Heldin C-H, Miyazono K 1993 Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGFβ type II receptor. Cell 75:681-692
6. Wrana JL, Attisano L, Wieser R, Ventura F, Massague J 1994 Mechanism of activation of the TGF-β receptor. Nature 370:341-347
7. Bassing CH, Yingling JM, Howe DJ, Wang T, He WW, Gustafson ML, Shah P, Donahoe PK, Wang X-F 1994 A transforming growth factor β type I receptor that signals to activate gene expression. Science 263:87-89
8. Carcamo J, Weis FMB, Ventura F, Wieser R, Wrana JL, Attisano L, Massague J 1994 Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor β and activin. Mol Cell Biol 14:3810-3821
9. Derynck R 1994 TGF-β-receptor-mediated signaling. Trends Biochem Sci 19:548-553
10. Massague J, Polyak K 1995 Mammalian antiproliferative signals and their targets. Curr Opin Gen Dev 5:91-96
11. Zhang Y, Feng X-H, Wu R-Y, Derynck R 1996 Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature 383:168-172
12. Graff JM, Bansal A, Melton DA 1996 Xenopus Mad proteins transduce distinct subsets of signals for the TGF-β superfamily. Cell 85:479-487
13. Hoodless PA, Haerry T, Abdollah S, Stapleton M, O'Connor MB, Attisano L, Wrana JL 1996 MADR1, a MAD-related protein that functions in BMP2 signaling pathways. Cell 85:489-500
14. Liu F, Hata A, Baker JC, Doody J, Carcamo J, Harland RM, Massague J 1996 A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381:620-623
15. ras farnesyltransferase α subunit in TGF-β and activin signaling. Science 271:1120-1122
16. Satoh T, Nakafuku M, Kaziro Y 1992 Function of ras as a molecular switch in signal transduction. J Biol Chem 267:24149-24152
17. Davis RJ 1993 The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268:14553-14556
18. Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, Matsumoto K 1995 Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270:2008-2011
19. ras by transforming growth factor β in epithelial cells. J Biol Chem 267:5029-5031
20. Yan Z, Winawer S, Friedman E 1994 Two different signal transduction pathways can be activated by transforming growth factor β1 in epithelial cells. J Biol Chem 269:13231-13237
21. mapk in proliferating cultures of epithelial cells. J Biol Chem 270:7117-7124
22. Weiss RH, Yabes AP, Sinaee R 1995 TGF-β and phorbol esters inhibit mitogenesis utilizing parallel protein kinase C-dependent pathways. Kidney Int 48:738-744
23. Franzen P, Ichijo H, Miyazono K 1993 Different signals mediate transforming growth factor-β1-induced growth inhibition and extracellular matrix production in prostatic carcinoma cells. Exp Cell Res 207:1-7
24. Markovac J, Goldstein GW 1988 Transforming growth factor beta activates protein kinase C in microvessels isolated from immature rat brain. Biochem Biophys Res Comm 150:575-582
25. Robertson PL, Markovac J, Datta SC, Golstein GW 1988 Transforming growth factor beta stimulates phosphoinositol metabolism and translocation of protein kinase C in cultured astrocytes. Neurosci Lett 93:107-113
26. Halstead J, Kemp K, Ignotz RA 1995 Evidence for involvement of phosphatidylcholine-phospholipase C and protein kinase C in transforming growth factor-β signaling. J Biol Chem 270:13600-13603
27. Lafon C, Mazars P, Guerrin M, Barboule N, Charcosset J-Y, Valette A 1995 Early gene responses associated with transforming growth factor-β1 growth inhibition and autoinduction in MCF-7 breast adenocarcinoma cells. Biochem Biophys Acta 1266:288-295
28. Guerrin M, Darbon JM, Guilbaud N, Monsarrat B, Valette A 1990 Transforming growth factor beta (TGF-β) reverses phorbol diester resistance of a breast adenocarcinoma (MCF-7) subline. Biochem Biophys Res Comm 166:687-694
29. Ito M, Yasui W, Kyo E, Yokozaki H, Nakayama H, Ito H, Tahara E 1992 Growth inhibition of transforming growth factor β on human gastric carcinoma cells: receptor and postreceptor signaling. Cancer Res 52:295-300
30. Ohtsuki M, Massague J 1992 Evidence for the involvement of protein kinase activity in transforming growth factor-β signal transduction. Mol Cell Biol 12:261-265
31. Nishikawa K, Yamamoto S, Nagumo H, Otsuka C, Kato R 1993 Suppressive effect of transforming growth factor-β on the phosphorylation of endogenous substrates by conventional and novel protein kinase C in primary cultured mouse epidermal cells. Biochem Biophys Res Comm 193:384-389
32. Nishizuka Y 1992 Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614
33. Dekker LV, Parker PJ 1994 Protein kinase C - a question of specificity. Trends Biochem Sci 19:73-77
34. Nishizuka Y 1995 Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 9:484-496
35. Lee C, Sutkowski DM, Sensibar JA, Zelner D, Kim I, Amsel I, Shaw N, Prins GS, Kozlowski JM 1995 Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone. Endocrinology 136:796-803
36. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
37. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ 1951 Protein measurement with the Folin-phenol reagent. J Biol Chem 193:265-275
38. Towbin H, Staehelin T, Gordon J 1979 Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354
39. Maizels ET, Miller JB, Cutler, Jr, RE, Jackiw V, Carney EM, Kern L, Hunzicker-Dunn M 1990 Calcium-independent phospholipid/diolein- dependent phosphorylation of a soluble ovarian Mr 80 000 substrate protein: biochemical characteristics. Biochim Biophys Acta 1054:285-296
40. Lamm MLG, Ekstrom RC, Maizels ET, Rajagopalan RM, Hunzicker-Dunn M 1994 The effect of protein kinases on desensitization of the porcine follicular membrane luteinizing hormone/chorionic gonadotropin-sensitive adenylyl cyclase. Endocrinology 134:1745-1754
41. Powell CT, Brittis NJ, Stec D, Hug H, Heston WDW, Fair WR 1996 Persistent membrane translocation of protein kinase Ca during 12-O-tetradecanoylphorbol-13-acetate-induced apoptosis of LNCaP human prostate cancer cells. Cell Growth Diff 7:419-428
42. Newton AC 1995 Protein kinase C: structure, function, and regulation J Biol Chem 270:28495-28498
43. Herbert JM, Augereau JM, Gleye J, Maffrand JP 1990 Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem Biophys Res Comm 172:993-999
44. Kim IY, Ahn H-J, Zelner DJ, Shaw JW, Sensibar JA, Kim J-H, Kato M, Lee C 1996 Genetic change in transforming growth factor β (TGF- β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells. Cancer Res 56:44-48
45. 2+ mobilization. Biochem Biophys Res Comm 210:378-383
46. 3 cells. J Biol Chem 265:7623-7631
47. Trilivas I, McDonough PM, Brown JH 1991 Dissociation of protein kinase C redistribution from the phosphorylation of its substrates. J Biol Chem 266:8431-8438
48. Ha K-S, Exton JH 1993 Differential translocation of protein kinase C isozymes by thrombin and platelet-derived growth factor. J Biol Chem 268:10534-10539
49. Hansra G, Bornancin F, Whelan R, Hemmings BA, Parker PJ 1996 12-O-Tetradecanoylphorbol-13-acetate-induced dephosphorylation of protein kinase Cα correlates with the presence of a membrane-associated protein phosphatase 2A heterotrimer. J Biol Chem 271:32785-32788
50. Gruppuso PA, Mikumo R, Brautigan DL, Braun L 1991 Growth arrest induced by transforming growth factor β1 is accompanied by protein phosphatase activation in human keratinocytes. J Biol Chem 266:3444-3448
51. Krongrad A, Bai G 1994 c-fos promoter insensitivity to phorbol ester and possible role of protein kinase C in androgen-independent cancer cells. Cancer Res 54:6073-6077
52. Wang X-H, Whyzmuzis CA, An S, Chen Y, Wu JM, Schneidau TA, Mallouh C, Tazaki H 1994 Regulation of cell growth and the c-myc proto-oncogene expression by phorbol ester 12-O-tetradecanoyl phorbol 13-acetate (TPA) in the androgen-independent human prostatic JCA-1 cells. Biochem Mol Biol Int 34:47-53
53. Novichenko N, Konno S, Nakajima Y, Hsieh TC, Xu W, Turo K, Ahmed T, Chiao JW 1995 Growth attenuation in a human prostate cell line mediated by a phorbol ester (43889). Proc Soc Exp Biol Med 209:152-156
54. Park K, Kim SJ, Bang YI, Park JG, Kim NK, Roberts AB, Sporn MB 1994 Genetic changes in the transforming growth factor (TGF-β) TβR-II gene in human gastric cancer cell: correlation with sensitivity to growth inhibition by TGF-β. Proc Natl Acad Sci USA 91:8772-8776