메뉴 건너뛰기




Volumn 185, Issue 1, 2010, Pages 25-32

Protein kinase Cγ in colon cancer cells: Expression, Thr514 phosphorylation and sensitivity to butyrate-mediated upregulation as related to the degree of differentiation

Author keywords

Butyrate; Caco2; HT29; PKC ; Thr514 phosphorylation

Indexed keywords

BUTYRIC ACID; PROTEIN KINASE C GAMMA; THREONINE; BUTYRIC ACID DERIVATIVE; PROTEIN KINASE C;

EID: 77950944074     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.02.035     Document Type: Article
Times cited : (13)

References (40)
  • 1
    • 0002449290 scopus 로고
    • Effects of butyrate on cell proliferation and gene expression
    • Cambridge University Press, Cambridge, J.H. Cummings, J.L. Rombeau, T. Sakata (Eds.)
    • Kruh J., Defer L., Tichonicky L. Effects of butyrate on cell proliferation and gene expression. Physiological and Clinical Aspects of Short-Chain Fatty Acids 1995, 275-288. Cambridge University Press, Cambridge. J.H. Cummings, J.L. Rombeau, T. Sakata (Eds.).
    • (1995) Physiological and Clinical Aspects of Short-Chain Fatty Acids , pp. 275-288
    • Kruh, J.1    Defer, L.2    Tichonicky, L.3
  • 2
    • 0001831910 scopus 로고
    • Toxicology of butyrate and short-chain fatty acids
    • Taylor and Francis, London, M.J. Hill (Ed.)
    • Csordas A. Toxicology of butyrate and short-chain fatty acids. Role of Gut Bacteria in Human Toxicology and Pharmacology 1995, 105-127. Taylor and Francis, London. M.J. Hill (Ed.).
    • (1995) Role of Gut Bacteria in Human Toxicology and Pharmacology , pp. 105-127
    • Csordas, A.1
  • 3
    • 10444282190 scopus 로고    scopus 로고
    • Histone-deacetylase inhibitors for the treatment of cancer
    • Lindemann R.K., Gabrielli B., Johnstone R.W. Histone-deacetylase inhibitors for the treatment of cancer. Cell Cycle 2004, 3:l779-1788.
    • (2004) Cell Cycle , vol.3
    • Lindemann, R.K.1    Gabrielli, B.2    Johnstone, R.W.3
  • 4
    • 34547864236 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: molecular mechanism of action
    • Xu W.S., Parmigiani R.B., Marks P.A. Histone deacetylase inhibitors: molecular mechanism of action. Oncogene 2007, 26:5541-5552.
    • (2007) Oncogene , vol.26 , pp. 5541-5552
    • Xu, W.S.1    Parmigiani, R.B.2    Marks, P.A.3
  • 5
    • 0034168037 scopus 로고    scopus 로고
    • Protein kinase C-mediated regulation of the cell cycle
    • Black J.D. Protein kinase C-mediated regulation of the cell cycle. Front. Biosci. 2000, 5:D406-D423.
    • (2000) Front. Biosci. , vol.5
    • Black, J.D.1
  • 6
    • 20644448807 scopus 로고    scopus 로고
    • The role of protein kinase C in gastrointestinal function and disease
    • Di Mari J.F., Mifflin R.C., Powell D.W. The role of protein kinase C in gastrointestinal function and disease. Gastroeneterology 2005, 128:2131-2146.
    • (2005) Gastroeneterology , vol.128 , pp. 2131-2146
    • Di Mari, J.F.1    Mifflin, R.C.2    Powell, D.W.3
  • 7
    • 0034645064 scopus 로고    scopus 로고
    • Protein kinase C signalling mediates a program of cell cycle withdrawal in the intestinal epithelium
    • Frey M.R., Clark J.A., Leontieva O., Uronis J.M., Black A.R., Black J.D. Protein kinase C signalling mediates a program of cell cycle withdrawal in the intestinal epithelium. J. Cell Biol. 2000, 151:763-778.
    • (2000) J. Cell Biol. , vol.151 , pp. 763-778
    • Frey, M.R.1    Clark, J.A.2    Leontieva, O.3    Uronis, J.M.4    Black, A.R.5    Black, J.D.6
  • 9
    • 33947603008 scopus 로고    scopus 로고
    • Protein kinase C and other diacyglycerol effectors in cancer
    • Griner E.M., Kazanietz M.G. Protein kinase C and other diacyglycerol effectors in cancer. Nat. Rev. Cancer 2007, 7:281-294.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 281-294
    • Griner, E.M.1    Kazanietz, M.G.2
  • 10
    • 0037283966 scopus 로고    scopus 로고
    • The structure and function of PKN, a protein kinase having a catalytic domain homologous to that of PKC
    • Mukai H. The structure and function of PKN, a protein kinase having a catalytic domain homologous to that of PKC. J. Biochem. 2003, 133:17-27.
    • (2003) J. Biochem. , vol.133 , pp. 17-27
    • Mukai, H.1
  • 11
    • 17144369501 scopus 로고    scopus 로고
    • Oxidative activation of protein kinase Cγ through the C1 domain
    • Lin D., Takemoto D.J. Oxidative activation of protein kinase Cγ through the C1 domain. J. Biol. Chem. 2005, 280:13682-13693.
    • (2005) J. Biol. Chem. , vol.280 , pp. 13682-13693
    • Lin, D.1    Takemoto, D.J.2
  • 12
    • 0035976977 scopus 로고    scopus 로고
    • The phosphoinositide-dependent kinase, PDK-1, phosphorylates conventional protein kinase C isoenzymes by a mechanism that is independent of phosphoinositide 3-kinase
    • Sonnenburg E.D., Gao T., Newton A.C. The phosphoinositide-dependent kinase, PDK-1, phosphorylates conventional protein kinase C isoenzymes by a mechanism that is independent of phosphoinositide 3-kinase. J. Biol. Chem. 2001, 276:45289-45297.
    • (2001) J. Biol. Chem. , vol.276 , pp. 45289-45297
    • Sonnenburg, E.D.1    Gao, T.2    Newton, A.C.3
  • 15
    • 0037337159 scopus 로고    scopus 로고
    • Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm
    • Newton A.C. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem. J. 2003, 370:361-371.
    • (2003) Biochem. J. , vol.370 , pp. 361-371
    • Newton, A.C.1
  • 16
    • 0034651539 scopus 로고    scopus 로고
    • Multiple pathways control protein kinase C phosphorylation
    • Parekh D.B., Ziegler W., Parker P.J. Multiple pathways control protein kinase C phosphorylation. EMBO J. 2000, 19:496-503.
    • (2000) EMBO J. , vol.19 , pp. 496-503
    • Parekh, D.B.1    Ziegler, W.2    Parker, P.J.3
  • 17
    • 0033525860 scopus 로고    scopus 로고
    • Carboxy-terminal phosphorylation regulates the function of subcellular localization of protein kinase C βII
    • Edwards A.S., Faux M.C., Scott A.C., Newton A.C. Carboxy-terminal phosphorylation regulates the function of subcellular localization of protein kinase C βII. J. Biol. Chem. 1999, 274:6461-6468.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6461-6468
    • Edwards, A.S.1    Faux, M.C.2    Scott, A.C.3    Newton, A.C.4
  • 18
    • 58349107283 scopus 로고    scopus 로고
    • Protein kinase C βII and PKCι/λ: collaborating partners in colon cancer promotion and progression
    • Murray N.R., Weems J., Braun U., Leitges M., Fields A.P. Protein kinase C βII and PKCι/λ: collaborating partners in colon cancer promotion and progression. Cancer Res. 2009, 69:656-662.
    • (2009) Cancer Res. , vol.69 , pp. 656-662
    • Murray, N.R.1    Weems, J.2    Braun, U.3    Leitges, M.4    Fields, A.P.5
  • 19
    • 60549085252 scopus 로고    scopus 로고
    • Protein kinase Cβ is an effective target for chemoprevention of colon cancer
    • Fields A.P., Calgano S.R., Krishna M., Rak S., Leitges M., Murray N.R. Protein kinase Cβ is an effective target for chemoprevention of colon cancer. Cancer Res. 2009, 69:1643-1650.
    • (2009) Cancer Res. , vol.69 , pp. 1643-1650
    • Fields, A.P.1    Calgano, S.R.2    Krishna, M.3    Rak, S.4    Leitges, M.5    Murray, N.R.6
  • 21
    • 3042647350 scopus 로고    scopus 로고
    • Protein kinase C and prostate carcinogenesis: targeting the cell cycle and apoptotic mechanisms
    • Gavrielides M.V., Frijhoff A.F., Conti C.J., Kazanietz M.G. Protein kinase C and prostate carcinogenesis: targeting the cell cycle and apoptotic mechanisms. Curr. Drug Targets 2004, 5:431-443.
    • (2004) Curr. Drug Targets , vol.5 , pp. 431-443
    • Gavrielides, M.V.1    Frijhoff, A.F.2    Conti, C.J.3    Kazanietz, M.G.4
  • 22
    • 0031779584 scopus 로고    scopus 로고
    • Resistance to high concentrations of methotrexate and 5-fluorouracil of differentiated HT-29 colon-cancer cells is restricted to cells of enterocytic phenotype
    • Lesuffleur T., Violette S., Vasile-Pandrea I., Dussaulx E., Brabat A., Muleris M., Zweibaum A. Resistance to high concentrations of methotrexate and 5-fluorouracil of differentiated HT-29 colon-cancer cells is restricted to cells of enterocytic phenotype. Int. J. Cancer 1998, 76:383-392.
    • (1998) Int. J. Cancer , vol.76 , pp. 383-392
    • Lesuffleur, T.1    Violette, S.2    Vasile-Pandrea, I.3    Dussaulx, E.4    Brabat, A.5    Muleris, M.6    Zweibaum, A.7
  • 23
    • 0021163443 scopus 로고
    • Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate
    • Augeron C., Laboisse C.L. Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. Cancer Res. 1984, 44:3961-3969.
    • (1984) Cancer Res. , vol.44 , pp. 3961-3969
    • Augeron, C.1    Laboisse, C.L.2
  • 24
    • 77950350447 scopus 로고    scopus 로고
    • Butyrate-induced cell death and differentiation are associated with distinct patterns of ROS in HT29-derived human colon cancer cells
    • Domokos M., Jakus J., Szeker K., Csizinszky R., Csiko Gy., Neogrady Zs., Csordas A., Galfi P. Butyrate-induced cell death and differentiation are associated with distinct patterns of ROS in HT29-derived human colon cancer cells. Dig. Dis. Sci. 2009, 10.1007/s10620-009r-r0820-6.
    • (2009) Dig. Dis. Sci.
    • Domokos, M.1    Jakus, J.2    Szeker, K.3    Csizinszky, R.4    Csiko, G.5    Neogrady, Z.6    Csordas, A.7    Galfi, P.8
  • 26
    • 0017184389 scopus 로고
    • A rapid and sensitive for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 27
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
    • Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 1979, 9:4350-4354.
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.9 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 28
    • 53349097707 scopus 로고    scopus 로고
    • Rac regulates the interaction of fascin with protein kinase C in cell migration
    • Parsons M., Adams J.C. Rac regulates the interaction of fascin with protein kinase C in cell migration. J. Cell Sci. 2008, 121:2805-2813.
    • (2008) J. Cell Sci. , vol.121 , pp. 2805-2813
    • Parsons, M.1    Adams, J.C.2
  • 29
    • 47049109143 scopus 로고    scopus 로고
    • PKC alpha protein but not kinase activity is critical for glioma cell proliferation and survival
    • Cameron A.J., Procyk K.J., Leitges M., Parker P.J. PKC alpha protein but not kinase activity is critical for glioma cell proliferation and survival. Int. J. Cancer 2008, 123:769-779.
    • (2008) Int. J. Cancer , vol.123 , pp. 769-779
    • Cameron, A.J.1    Procyk, K.J.2    Leitges, M.3    Parker, P.J.4
  • 30
    • 0033957432 scopus 로고    scopus 로고
    • Short-chain fatty acids reduce expression of specific protein kinase C isoforms in human colonic epithelial cells
    • Rickard K.L., Gibson P.R., Wilson N.J., Mariadason J.M., Phillips W.A. Short-chain fatty acids reduce expression of specific protein kinase C isoforms in human colonic epithelial cells. J. Cell Phys. 2000, 182:222-231.
    • (2000) J. Cell Phys. , vol.182 , pp. 222-231
    • Rickard, K.L.1    Gibson, P.R.2    Wilson, N.J.3    Mariadason, J.M.4    Phillips, W.A.5
  • 31
    • 17044411372 scopus 로고    scopus 로고
    • Bile acid dexycholate induces differential subcellular localisation of the PKC isoenzymes β1, e{open} and δ in colonic epithelial cells in a sodium butyrate insensitive manner
    • Looby E., Long A., Keelleher D., Volkov Y. Bile acid dexycholate induces differential subcellular localisation of the PKC isoenzymes β1, e{open} and δ in colonic epithelial cells in a sodium butyrate insensitive manner. Int. J. Cancer 2005, 114:887-895.
    • (2005) Int. J. Cancer , vol.114 , pp. 887-895
    • Looby, E.1    Long, A.2    Keelleher, D.3    Volkov, Y.4
  • 33
    • 0036856263 scopus 로고    scopus 로고
    • Protein kinase Cγ (PKCγ): function of neuron specific isotype
    • Saito N., Shirai Y. Protein kinase Cγ (PKCγ): function of neuron specific isotype. J. Biochem. 2002, 132:683-687.
    • (2002) J. Biochem. , vol.132 , pp. 683-687
    • Saito, N.1    Shirai, Y.2
  • 35
    • 0033966613 scopus 로고    scopus 로고
    • Interplay between the gamma isoform of PKC and calcineurin in regulation of vulnerability to focal cerebral ischemia
    • Aronowski J., Grotta J.C., Strong R., Waxham M.N. Interplay between the gamma isoform of PKC and calcineurin in regulation of vulnerability to focal cerebral ischemia. J. Cereb. Blood Flow Metab. 2000, 20:343-349.
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 343-349
    • Aronowski, J.1    Grotta, J.C.2    Strong, R.3    Waxham, M.N.4
  • 36
    • 0035021863 scopus 로고    scopus 로고
    • Protein kinase C isoenzymes: guilt by omission
    • Black J.D. Protein kinase C isoenzymes: guilt by omission. Gastroenterology 2001, 120:1868-1872.
    • (2001) Gastroenterology , vol.120 , pp. 1868-1872
    • Black, J.D.1
  • 38
    • 0031782443 scopus 로고    scopus 로고
    • Colonocyte differentiation is associated with increased expression and altered distribution of protein kinase C isozymes
    • Vestovsek G., Byrd A., Frey M.R., Petrelli N.J., Black J.D. Colonocyte differentiation is associated with increased expression and altered distribution of protein kinase C isozymes. Gastroenterology 1998, 115:75-85.
    • (1998) Gastroenterology , vol.115 , pp. 75-85
    • Vestovsek, G.1    Byrd, A.2    Frey, M.R.3    Petrelli, N.J.4    Black, J.D.5
  • 39
    • 0033524359 scopus 로고    scopus 로고
    • Anti-proliferative activity of protein kinase C in apical compartments of human colonic crypts: evidence for a less activated protein kinase C in small adenomas
    • Assert R., Kötter R., Bisping G., Scheppach W., Stahlnecker E., Müller K.M., Dusel G., Schatz H., Pfeiffer A. Anti-proliferative activity of protein kinase C in apical compartments of human colonic crypts: evidence for a less activated protein kinase C in small adenomas. Int. J. Cancer 1999, 80:47-53.
    • (1999) Int. J. Cancer , vol.80 , pp. 47-53
    • Assert, R.1    Kötter, R.2    Bisping, G.3    Scheppach, W.4    Stahlnecker, E.5    Müller, K.M.6    Dusel, G.7    Schatz, H.8    Pfeiffer, A.9
  • 40
    • 0032924312 scopus 로고    scopus 로고
    • Protein kinases C-γ and -δ are involved in insulin-like growth factor I-induced migration of colonic epithelial cells
    • André F., Rigot V., Remacle-Bonnet M., Luis J., Pommier G., Marvaldi J. Protein kinases C-γ and -δ are involved in insulin-like growth factor I-induced migration of colonic epithelial cells. Gastroenterology 1999, 116:64-77.
    • (1999) Gastroenterology , vol.116 , pp. 64-77
    • André, F.1    Rigot, V.2    Remacle-Bonnet, M.3    Luis, J.4    Pommier, G.5    Marvaldi, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.