Age and disability accumulation in multiple sclerosis

Neurology

Volumn 77, Issue 13, 2011, Pages 1246-1252

  Scalfari, A ^a   Neuhaus, A ^a   Daumer, M ^a   Ebers, G C ^a   Muraro, P A ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE; AGED; ARTICLE; DISABILITY INDEX; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; FEMALE; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; ONSET AGE; PHYSICAL DISABILITY; PRIORITY JOURNAL; PROGNOSIS; RATING SCALE; RELAPSE; REMISSION; SCORING SYSTEM; ADOLESCENT; AGING; CANADA; DISABILITY; DISABLED PERSON; KAPLAN MEIER METHOD; LONGITUDINAL STUDY; PATHOPHYSIOLOGY; PREDICTIVE VALUE; RETROSPECTIVE STUDY; STATISTICAL MODEL; STATISTICS;

ADOLESCENT; ADULT; AGE OF ONSET; AGING; DISABILITY EVALUATION; DISABLED PERSONS; DISEASE PROGRESSION; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; MULTIPLE SCLEROSIS; ONTARIO; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 82255160649     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e318230a17d     Document Type: Article

References (26)

1. Hawkins SA, McDonnell GV. Benign multiple sclerosis? Clinical course, long term follow up, and assessment of prognostic factors. J Neurol Neurosurg Psychiatry 1999; 67:148-152. (Pubitemid 29326942)
2. Ramsaransing GS, De Keyser J. Benign course in multiple sclerosis: a review. Acta Neurol Scand 2006;113:359-369. (Pubitemid 44046321)
3. Lublin FD, Reingold SC. Defining the clinical course of multiple sclerosis: results of an international survey: National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis Neurology 1996;46:907-911.
4. Confavreux C, Vukusic S, Moreau T, Adeleine P. Relapses and progression of disability in multiple sclerosis. N Engl J Med 2000;343:1430-1438.
5. Confavreux C, Vukusic S, Adeleine P. Early clinical predictors and progression of irreversible disability in multiple sclerosis: an amnesic process. Brain 2003;126:770-782. (Pubitemid 36372978)
6. Leray E, Yaouanq J, Le Page E, et al. Evidence for a twostage disability progression in multiple sclerosis. Brain 2010;133:1900-1913.
7. Scalfari A, Neuhaus A, Degenhardt A, et al. The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability. Brain 2010;133: 1914-1929.
8. Kremenchutzky M, Rice GP, Baskerville J, Wingerchuk DM, Ebers GC. The natural history of multiple sclerosis: a geographically based study 9: observations on the progressive phase of the disease. Brain 2006;129:584-594. (Pubitemid 43278221)
9. Weinshenker BG, Rice GP, Noseworthy JH, Carriere W, Baskerville J, Ebers GC. The natural history of multiple sclerosis: a geographically based study: 3: multivariate analysis of predictive factors and models of outcome. Brain 1991;114:1045-1056.
10. Runmarker B, Andersen O. Prognostic factors in a multiple sclerosis incidence cohort with twenty-five years of follow-up. Brain 1993;116:117-134. (Pubitemid 23087038)
11. Kantarci O, Siva A, Eraksoy M, et al. Survival and predictors of disability in Turkish MS patients: Turkish Multiple Sclerosis Study Group (TUMSSG). Neurology 1998;51: 765-772. (Pubitemid 28449257)
12. Poser S, Raun NE, Poser W. Age at onset, initial symptomatology and the course of multiple sclerosis. Acta Neurol Scand 1982;66:355-362. (Pubitemid 12061611)
13. Riise T, Gronning M, Fernandez O, et al. Early prognostic factors for disability in multiple sclerosis, a European multicenter study. Acta Neurol Scand 1992;85:212-218.
14. Phadke JG. Clinical aspects of multiple sclerosis in northeast Scotland with particular reference to its course and prognosis. Brain 1990;113:1597-1628.
15. Fog T, Linnemann F. The course of multiple sclerosis in 73 cases with computer-designed curves. Acta Neurol Scand Suppl 1970;47:3-175.
16. Confavreux C, Aimard G, Devic M. Course and prognosis of multiple sclerosis assessed by the computerized data processing of 349 patients. Brain 1980;103:281-300. (Pubitemid 10046624)
17. Cottrell DA, Kremenchutzky M, Rice GP, et al. The natural history of multiple sclerosis: a geographically based study: 5: the clinical features and natural history of primary progressive multiple sclerosis. Brain 1999; 122:625-639. (Pubitemid 29158771)
18. Koch M, Mostert J, Heersema D, De Keyser J. Progression in multiple sclerosis: further evidence of an age dependent process. J Neurol Sci 2007;255:35-41. (Pubitemid 46414019)
19. Confavreux C, Vukusic S. Natural history of multiple sclerosis: a unifying concept. Brain 2006;129:606-616. (Pubitemid 43278223)
20. Confavreux C, Vukusic S. Age at disability milestones in multiple sclerosis. Brain 2006;129:595-605. (Pubitemid 43278222)
21. Kurtzke JF. A new scale for evaluating disability in multiple sclerosis. Neurology 1955;5:580-583.
22. Hader WJ, Elliot M, Ebers GC. Epidemiology of multiple sclerosis in London and Middlesex County, Ontario, Canada. Neurology 1988;38:617-621.
23. Weinshenker BG, Bass B, Rice GP, et al. The natural history of multiple sclerosis: a geographically based study: I: clinical course and disability. Brain 1989;112:133-146. (Pubitemid 19056478)
24. Kremenchutzky M, Cottrell D, Rice G, et al. The natural history of multiple sclerosis: a geographically based study: 7: progressive-relapsing and relapsing-progressive multiple sclerosis: a re-evaluation. Brain 1999;122:1941-1950.
25. Daumer M, Held U, Ickstadt K, Heinz M, Schach S, Ebers G. Reducing the probability of false positive research findings by pre-publication validation: experience with a large multiple sclerosis database. BMC Med Res Methodol 2008;8:18.
26. R Foundation for Statistical Computing. R: A Language and Environment for Statistical Computing. Vienna: R Foundation for Statistical Computing; 2008.