MRP8 promotes Th17 differentiation via upregulation of IL-6 production by fibroblast-like synoviocytes in rheumatoid arthritis

Experimental and Molecular Medicine

Volumn 45, Issue 4, 2013, Pages

  Lee, Dong Gun ^a   Woo, Jung Won ^a   Kwok, Seung Ki ^b   Cho, Mi La ^a   Park, Sung Hwan ^b  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Fibroblast like synoviocytes; IL 6; MRP8; Rheumatoid arthritis; Th17 differentiation

Indexed keywords

CELL PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 6; MESSENGER RNA; MYELOID RELATED PROTEIN 8; PHOSPHATIDYLINOSITOL 3 KINASE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; ABC TRANSPORTER; ABCC11 PROTEIN, HUMAN; AUTACOID; CALGRANULIN B; IL6 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; ATTENUATION; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CLINICAL ARTICLE; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; FIBROBLAST LIKE SYNOVIOCYTE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERLEUKIN 17 GENE; OSTEOARTHRITIS; PERIPHERAL BLOOD MONONUCLEAR CELL; POLARIZATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIAL FLUID; SYNOVIOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL; UPREGULATION; BIOSYNTHESIS; CYTOLOGY; FIBROBLAST; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY; SYNOVIUM;

ADULT; AGED; ARTHRITIS, RHEUMATOID; ATP-BINDING CASSETTE TRANSPORTERS; CALGRANULIN B; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; FIBROBLASTS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-17; INTERLEUKIN-6; MIDDLE AGED; SIGNAL TRANSDUCTION; SYNOVIAL FLUID; SYNOVIAL MEMBRANE; TH17 CELLS; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 84878328732     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2013.39     Document Type: Article

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