One-step spray-dried polyelectrolyte microparticles enhance the antigen cross-presentation capacity of porcine dendritic cells

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 84, Issue 2, 2013, Pages 421-429

  Devriendt, Bert ^a   Baert, Kim ^a   Dierendonck, Marijke ^a   Favoreel, Herman ^a   De Koker, Stefaan ^a   Remon, Jean Paul ^a   De Geest, Bruno G ^a   Cox, Eric ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Cross presentation; Dendritic cells; F4 fimbriae; Microparticles; Polyelectrolytes; Porcine

Indexed keywords

CD40 ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; POLYELECTROLYTE;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CD8+ T LYMPHOCYTE; CELL MATURATION; CROSS PRESENTATION; CYTOKINE RELEASE; DENDRITIC CELL; DRUG DELIVERY SYSTEM; ENCAPSULATION; ENTEROTOXIGENIC ESCHERICHIA COLI; FIMBRIA; IMMUNOGENICITY; NANOFABRICATION; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; SPRAY DRYING; T LYMPHOCYTE ACTIVATION;

ADHESINS, BACTERIAL; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; ANTIGENS, CD40; CROSS-PRIMING; DENDRITIC CELLS; ELECTROLYTES; ENDOCYTOSIS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FIMBRIAE PROTEINS; INTERLEUKIN-1BETA; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-6; PARTICLE SIZE; PHENOTYPE; SWINE;

EID: 84878322223     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.11.016     Document Type: Article

References (50)

1. D. Normile Rinderpest driven to extinction Science 319 2008 1606 1609
2. S.A. Plotkin Vaccines: the fourth century Clin. Immunol. Vaccinol. 16 2009 1709 1719
3. S.A. Plotkin, and S.L. Plotkin The development of vaccines: how the past led to the future Nat. Rev. Microbiol. 9 2011 889 893
4. J.J. Moon, B. Huang, and D.J. Irvine Engineering nano- and microparticles to tune immunity Adv. Mater. 24 2012 3724 3746
5. R.M. Steinman, and J. Banchereau Taking dendritic cells into medicine Nature 449 2007 419 426
6. W.L. Jiang, R.K. Gupta, M.C. Deshpande, and S.P. Schwendeman Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens Adv. Drug Deliv. Rev. 57 2005 391 410
7. A. Sexton, P.G. Whitney, S.-F. Chong, A.N. Zelikin, A.P.R. Johnston, R. De Rose, A.G. Brooks, F. Caruso, and S.J. Kent A protective vaccine delivery system for in vivo T cell stimulation using nanoengineered polymer hydrogel capsules ASC Nano 3 2009 3391 3400
8. L.J. De Cock, S. De Koker, B.G. De Geest, J. Grooten, C. Vervaet, J.P. Remon, G.B. Sukhorukov, and M.N. Antipina Polymeric multilayer capsules in drug delivery Angew. Chem. Int. Ed. Engl. 49 2010 6954 6973
9. S. De Koker, T. Naessens, B.G. De Geest, P. Bogaert, J. Demeester, S. De Smedt, and J. Grooten Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery J. Immunol. 184 2010 203 211
10. S. De Koker, L.J. De Cock, P. Rivera-Gil, W.J. Parak, R. Auzély Velty, C. Vervaet, J.P. Remon, J. Grooten, and B.G. De Geest Polymeric multilayer capsules delivering biotherapeutics, Adv Drug Deliv. Rev. 63 2011 748 761
11. S. De Koker, R. Hoogenboom, and B.G. De Geest Polymeric multilayer capsules for drug delivery Chem. Soc. Rev. 41 2012 2867 2884
12. Y. Yan, G.K. Such, A.P. Johnston, H. Lomas, and F. Caruso Toward therapeutic delivery with layer-by-layer engineered particles ACS Nano 5 2011 4252 4257
13. B.G. De Geest, M.A. Willart, H. Hammad, B.N. Lambracht, C. Pollard, P. Bogaert, M. De Filette, X. Saelens, C. Vervaet, J.P. Remon, J. Grooten, and S. De Koker Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection ASC Nano 6 2012 2136 2149
14. B.G. De Geest, M.A. Willart, B.N. Lambrecht, C. Pollard, C. Vervaet, J.P. Remon, J. Grooten, and S. De Koker Surface engineered polyelectrolyte multilayer capsules-synthetic vaccines mimicking microbial structure and function Angew. Chem. 51 2012 3862 3866
15. G. Decher Fuzzy nanoassembllies: toward layered polymeric multicomposites Science 277 1997 1232 1237
16. F. Caruso, R.A. Caruso, and H. Mohwald Nanoengineering of inorganic and hybrid hollow spheres bu colloidal templating Science 282 1998 1111 1114
17. E. Donath, G.B. Sukhorukov, F. Caruso, and S.A. Davis Novel hollow polymer shells by colloid-templated assembly of polyelectrolytes Angew. Chem. Int. Ed. 37 1998 2201 2205
18. M. Dierendonck, S. De Koker, C. Cuvelier, J. Grooten, C. Vervaet, J.P. Remon, and B.G. De Geest Facile two-step synthesis of porous antigen-loaded degradable polyelectrolyte microspheres Angew. Chem. Int. Ed. Engl. 49 2010 8620 8624
19. M. Dierendonck, S. De Koker, R. De Rycke, P. Bogaert, J. Grooten, C. Vervaet, J.P. Remon, and B.G. De Geest Single-step formation of degradable intracellular biomolecule microreactors ACS Nano 5 2011 6886 6893
20. J.M. Fairbrother, E. Nadeau, and C.L. Gyles Escherichia coli in postweaning disease in pigs: an update on bacterial types, pathogenesis, and prevention strategies Anim. Health Res. Rev. 6 2005 17 39
21. E. Cox, Y. Van der Stede, F. Verdonck, V. Snoeck, W. Van den Broeck, and B. Goddeeris Oral immunizations of pigs with fimbrial antigens of enterotoxigenic E. coli: an interesting model to study mucosal immune mechanisms Vet. Immunol. Immunopathol. 87 2002 287 290
22. W. Van den Broeck, E. Cox, and B.M. Goddeeris Receptor-dependent immune responses in pigs after oral immunization with F4 fimbriae Infect. Immun. 67 1999 520 526
23. + intestinal antigen presenting cells and antigen-specific immune responses, leading to a prolonged intestinal ETEC infection Vet. Res. 40 2009 40
24. B. Devriendt, F. Verdonck, A. Summerfield, B.M. Goddeeris, and E. Cox Targeting of Escherichia coli F4 fimbriae to Fcγ receptors enhances the maturation of porcine dendritic cells Vet. Immunol. Immunopathol. 135 2010 188 198
25. V. Melkebeek, K. Rasschaert, P. Bellot, K. Tilleman, H. Favoreel, D. Deforce, B.G. De Geest, B.M. Goddeeris, and E. Cox Targeting aminopeptidase N, a newly identified receptor for F4ac fimbriae, enhances the intestinal mucosal immune response Mucosal Immunol. 5 2012 635 645
26. L. Fairbairn, R. Kapetanovic, D.P. Sester, and D.A. Hume The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease J. Leuk. Biol. 89 2011 855 871
27. F. Meurens, A. Summerfield, H. Nauwynck, L. Saif, and V. Gerdts The pig: a model for human infectious diseases Trends Microbiol. 20 2012 50 57
28. T. Verfaillie, V. Melkebeek, V. Snoeck, S. Douterlungne, F. Verdonck, D. Vanrompay, B. Goddeeris, and E. Cox Priming of piglets against enterotoxigenic E. coli F4 fimbriae by immunization with FAEG DNA Vaccine 22 2004 1640 1647
29. M.D. Pescovitz, J.K. Lunney, and D.H. Sachs Preparation and characterization of monoclonal antibodies reactive with porcine PBL J. Immunol. 133 1984 368 375
30. S. Inumaru, T. Kokuho, S. Denham, M.S. Denyer, E. Momotani, S. Kitamura, A. Corteyn, S. Brookes, R.M. Parkhouse, and H. Takamatsu Expression of biologically active recombinant porcine GM-CSF by baculovirus gene expression system Immunol. Cell Biol. 76 1998 195 201
31. C.P. Carrasco, R.C. Rigden, R. Schaffner, H. Gerber, V. Neuhaus, S. Inumaru, H. Takamatsu, G. Bertoni, K.C. McCullough, and A. Summerfield Porcine dendritic cells generated in vitro: morphological, phenotypic and functional properties Immunology 104 2001 175 184
32. J.K. Lunney, K. Walker, T. Goldman, B. Aasted, A. Bianchi, and R. Binns Overview of the first international workshop to define swine leukocyte cluster of differentiation (CD) antigens Vet. Immunol. Immunopathol. 43 1994 193 206
33. D. Bimczok, H. Rau, N. Wundrack, M. Naumann, H.J. Rothkötter, K. McCullough, and A. Summerfield Cholera toxin promotes the generation of semi-mature porcine monocyte-derived dendritic cells that are unable to stimulate T cells Vet. Res. 38 2007 597 612
34. M. Bailey, K. Stevens, P.W. Bland, and C.R. Stokes A monoclonal antibody recognising an epitope associated with pig interleukin-2 receptors J. Immunol. Methods 153 1992 85 91
35. +-E. coli by the intramuscular immunisation of suckling piglets by administration of 1α,25-dihydroxyvitamin D3 or CpG-oligonucleotides Vaccine 21 2003 1023 1032
36. A. Saalmüller, B. Aasted, A. Canals, J. Dominguez, T. Goldman, J.K. Lunney, S. Maurer, T. Pauly, M.D. Pescovitz, and R. Pospisil Analyses of monoclonal antibodies reactive with porcine CD6 Vet. Immunol. Immunopathol. 43 1994 243 247
37. S. Jonjic, and U.H. Koszinowski Monoclonal antibodies reactive with swine lymphocytes. I. Antibodies to membrane structures that define the cytolytic T lymphocyte subset in the swine J. Immunol. 133 1998 647 652
38. C. Pilon, B. Levast, F. Meurens, Y. Le Vern, D. Kerboeuf, H. Salmon, F. Velge-Roussel, Y. Lebranchu, and C. Baron CD40 engagement strongly induces CD25 expression on porcine dendritic cells and polarizes the T cell immune response toward Th1 Mol. Immunol. 46 2009 437 447
39. + T cells Science 327 2010 1098 1102
40. S. De Koker, B.G. De Geest, S.K. Singh, R. De Rycke, T. Naessens, Y. Van Kooyk, J. Demeester, S.C. De Smedt, and J. Grooten Polyelectrolyte microcapsules as antigen delivery vehicle to dendritic cells: uptake, processing, and cross-presentation of encapsulated antigens Angew. Chem. Int. Ed. 48 2009 8485 8489
41. S. Fischer, E. Uetz-Von Allmen, Y. Waeckerle-Men, M. Groettrup, H.P. Merkle, and B. Gander The preservation of phenotype and functionality of dendritic cells upon phagocytosis of poly-electrolyte-coated PLGA microparticles Biomaterials 28 2007 994 1004
42. L. Zhou, and D.R. Littman Transcriptional regulatory networks in Th17 cell differentiation Curr. Opin. Immunol. 21 2009 146 152
43. T.G. Kiros, J. van Kessel, L.A. Babiuk, and V. Gerdts Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC, thymus, and lung lymphocytes of young pigs Vet. Immunol. Immunopathol. 144 2011 448 454
44. M.H. Shaw, N. Kamada, Y.G. Kim, and G. Núñez Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cell in the intestine J. Exp. Med. 209 2012 251 258
45. J.J. Moon, H. Suh, A. Bershteyn, M.T. Stephan, H. Liu, B. Huang, M. Sohail, S. Luo, S. Hu Om, H. Khant, J.T. Goodwin, J. Ramos, W. Chiu, and J.D. Irvine Nat. Mater. 10 2011 243 251
46. M. Dierendonck, S. De Koker, C. Vervaet, J.P. Remon, and B.G. De Geest Interaction between polymeric multilayer capsules and immune cells J. Control. Release 161 2012 592 599
47. M.M.J. Kamphuis, A.P.R. Johnston, G.K. Such, H.H. Dam, R.A. Evans, A.M. Scott, E.C. Nice, J.K. Heath, and F. Caruso Targeting of cancer cells using click-functionalized polymer capsules J. Am. Chem. Soc. 132 2010 15881 15883
48. B. Devriendt, B.G. De Geest, and E. Cox Designing oral vaccines targeting intestinal dendritic cells Exp. Opin. Drug Deliv. 8 2011 467 483
49. B. Devriendt, B.G. De Geest, B.M. Goddeeris, and E. Cox Crossing the barrier: targeting epithelial receptors for enhanced oral vaccine delivery J. Control. Release 160 2012 431 439
50. F. Verdonck, E. Cox, and B.M. Goddeeris F4 fimbriae expressed by porcine enterotoxigenic Escherichia coli, an example of an eccentric fimbrial system J. Mol. Microbiol. Biotechnol. 7 2004 155 169