Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers

Science Translational Medicine

Volumn 5, Issue 186, 2013, Pages

  Rousseaux, Sophie ^a,b   Debernardi, Alexandra ^a,b   Jacquiau, Baptiste ^a,b   Vitte, Anne Laure ^a,b   Vesin, Aurélien ^a,b   Nagy Mignotte, Hélène ^c   Moro Sibilot, Denis ^c   Brichon, Pierre Yves ^c   Lantuejoul, Sylvie ^c   Hainaut, Pierre ^d   Laffaire, Julien ^e   De Reyniès, Aurélien ^e   Beer, David G ^f   Timsit, Jean François ^a,b,c   Brambilla, Christian ^a,b,c   Brambilla, Elisabeth ^a,b,c   Khochbin, Saadi ^a,b  

^a INSERM   (France)

^b INSTITUT ALBERT BONNIOT   (France)

^c GRENOBLE UNIVERSITY HOSPITAL   (France)

^d INTERNATIONAL PREVENTION RESEARCH INSTITUTE   (France)

^e Cartes d'Identité des Tumeurs Program   (France)

^f UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; EMBRYONIC STEM CELL; EPIGENETICS; EXPRESSED SEQUENCE TAG; FEMALE; GENE; GENE ACTIVATION; GENE EXPRESSION; GERM CELL; HUMAN; HUMAN TISSUE; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; METASTASIS; PLACENTA SPECIFIC GENE; PRIORITY JOURNAL; PROMOTER REGION; SOMATIC CELL; TESTIS SPECIFIC GENE; TRANSCRIPTOMICS;

ANIMALS; CELL LINE, TUMOR; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GERM CELLS; HUMANS; LUNG NEOPLASMS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM STAGING; ORGAN SPECIFICITY; PLACENTA; PREGNANCY; PROGNOSIS; PROMOTER REGIONS, GENETIC; REPRODUCIBILITY OF RESULTS; TRANSCRIPTOME;

EID: 84878305885     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3005723     Document Type: Article

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