The 'Hygiene hypothesis' and the sharp gradient in the incidence of autoimmune and allergic diseases between Russian Karelia and Finland

APMIS

Volumn 121, Issue 6, 2013, Pages 478-493

  Kondrashova, Anita ^a   Seiskari, Tapio ^a,b   Ilonen, Jorma ^c,d   Knip, Mikael ^e,f,g,h   Hyöty, Heikki ^a,b  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b FIMLAB LABORATORIES   (Finland)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d UNIVERSITY OF TURKU   (Finland)

^e UNIVERSITY OF HELSINKI   (Finland)

^f HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^g FOLKHÄLSAN RESEARCH CENTER   (Finland)

^h TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Allergy; Autoimmune diseases; Finland; Hygiene hypothesis; Infections; Russian Karelia

Indexed keywords

ALLERGIC DISEASE; ALLERGIC REACTION; ARTICLE; ASTHMA; AUTOIMMUNE DISEASE; BACTEROIDES; BACTEROIDES FRAGILIS; BIFIDOBACTERIUM; CLOSTRIDIUM; CLOSTRIDIUM DIFFICILE; ENTEROBACTER; ENTEROBACTERIACEAE; ENVIRONMENTAL FACTOR; ESCHERICHIA COLI; FINLAND; HELMINTH; HUMAN; HYGIENE HYPOTHESIS; IMMUNE RESPONSE; INCIDENCE; INFECTION; KLEBSIELLA; LACTOBACILLUS; MICROBIOME; MYCOBACTERIUM; PREVALENCE; PRIORITY JOURNAL; RUSSIAN FEDERATION; SAPROTROPH; STREPTOCOCCUS;

ANIMALS; AUTOIMMUNE DISEASES; BACTERIA; CYTOKINES; DIABETES MELLITUS, TYPE 1; FINLAND; HUMANS; HYGIENE HYPOTHESIS; HYPERSENSITIVITY; INCIDENCE; METAGENOME; MICE; MICE, INBRED NOD; RUSSIA; SOCIOECONOMIC FACTORS;

EID: 84878247477     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/apm.12023     Document Type: Article

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