-
3
-
-
76049128595
-
Estimates of cancer incidence and mortality in Europe in 2008
-
Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010;46:765-781
-
(2010)
Eur J Cancer
, vol.46
, pp. 765-781
-
-
Ferlay, J.1
Parkin, D.M.2
Steliarova-Foucher, E.3
-
4
-
-
84874566782
-
European cancer mortality predictions for the year 2013
-
Malvezzi M, Bertuccio P, Levi F et al. European cancer mortality predictions for the year 2013. Ann Oncol 2013;24:792-800
-
(2013)
Ann Oncol
, vol.24
, pp. 792-800
-
-
Malvezzi, M.1
Bertuccio, P.2
Levi, F.3
-
6
-
-
80054690379
-
Characterising the castration-resistant prostate cancer population: A systematic review
-
Kirby M, Hirst C, Crawford ED. Characterising the castration-resistant prostate cancer population: A systematic review. Int J Clin Pract 2011;65: 1180-1192
-
(2011)
Int J Clin Pract
, vol.65
, pp. 1180-1192
-
-
Kirby, M.1
Hirst, C.2
Crawford, E.D.3
-
7
-
-
0028944138
-
In vivo amplification of the androgen receptor gene and progression of human prostate cancer
-
Visakorpi T, Hyytinen E, Koivisto P et al. In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat Genet 1995;9:401-406
-
(1995)
Nat Genet
, vol.9
, pp. 401-406
-
-
Visakorpi, T.1
Hyytinen, E.2
Koivisto, P.3
-
8
-
-
0033767930
-
Androgenreceptorgeneamplification at primary progression predicts response to combined androgen blockade as second line therapy for advanced prostate cancer
-
Palmberg C, Koivisto P, Kakkola L et al. Androgenreceptorgeneamplification at primary progression predicts response to combined androgen blockade as second line therapy for advanced prostate cancer. J Urol 2000;164:1992-1995
-
(2000)
J Urol
, vol.164
, pp. 1992-1995
-
-
Palmberg, C.1
Koivisto, P.2
Kakkola, L.3
-
9
-
-
0141954183
-
Androgen receptor gene amplification and protein expression in recurrent prostate cancer
-
Ford OH, III, Gregory CW, Kim D et al. Androgen receptor gene amplification and protein expression in recurrent prostate cancer. J Urol 2003;170:1817-1821
-
(2003)
J Urol
, vol.170
, pp. 1817-1821
-
-
Ford III., O.H.1
Gregory, C.W.2
Kim, D.3
-
10
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
Chen CD, Welsbie DS, Tran C et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004;10:33-39
-
(2004)
Nat Med
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
-
11
-
-
77956357165
-
Detection of androgen receptor mutations in circulating tumor cells in castration-resistant prostate cancer
-
Jiang Y, Palma JF, Agus DB et al. Detection of androgen receptor mutations in circulating tumor cells in castration-resistant prostate cancer. Clin Chem 2010;56:1492-1495
-
(2010)
Clin Chem
, vol.56
, pp. 1492-1495
-
-
Jiang, Y.1
Palma, J.F.2
Agus, D.B.3
-
12
-
-
66249135684
-
Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy
-
Steinkamp MP, O'Mahony OA, BrogleyMet al. Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy. Cancer Res 2009;69:4434-4442
-
(2009)
Cancer Res
, vol.69
, pp. 4434-4442
-
-
Steinkamp, M.P.1
O'Mahony, O.A.2
Brogley, M.3
-
13
-
-
0034895975
-
Collocation ofandrogenreceptorgenemutations in prostate cancer
-
Buchanan G, Greenberg NM, Scher HI et al. Collocation ofandrogenreceptorgenemutations in prostate cancer. Clin Cancer Res 2001;7:1273-1281
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1273-1281
-
-
Buchanan, G.1
Greenberg, N.M.2
Scher, H.I.3
-
14
-
-
66149098947
-
Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castrationresistant prostate cancer
-
Attard G, Swennenhuis JF, OlmosDet al. Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castrationresistant prostate cancer. Cancer Res 2009;69: 2912-2918
-
(2009)
Cancer Res
, vol.69
, pp. 2912-2918
-
-
Attard, G.1
Swennenhuis, J.F.2
Olmos, D.3
-
15
-
-
78649966606
-
Androgeninduced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells
-
Bastus NC, Boyd LK, Mao X et al. Androgeninduced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells. Cancer Res 2010;70:9544-9548
-
(2010)
Cancer Res
, vol.70
, pp. 9544-9548
-
-
Bastus, N.C.1
Boyd, L.K.2
Mao, X.3
-
16
-
-
0037222317
-
The transcriptional co-activator cAMP response element-binding protein-binding protein is expressed in prostate cancer and enhances androgen-and anti-androgen-induced androgen receptor function
-
Comuzzi B, Lambrinidis L, RogatschHet al. The transcriptional co-activator cAMP response element-binding protein-binding protein is expressed in prostate cancer and enhances androgen-and anti-androgen-induced androgen receptor function. AmJ Pathol 2003;162:233-241
-
(2003)
AmJ Pathol
, vol.162
, pp. 233-241
-
-
Comuzzi, B.1
Lambrinidis, L.2
Rogatsch, H.3
-
17
-
-
12344338583
-
Expression and function of androgen receptor coactivators in prostate cancer
-
Culig Z, Comuzzi B, Steiner H et al. Expression and function of androgen receptor coactivators in prostate cancer. J Steroid Biochem Mol Biol 2004; 92:265-271
-
(2004)
J Steroid Biochem Mol Biol
, vol.92
, pp. 265-271
-
-
Culig, Z.1
Comuzzi, B.2
Steiner, H.3
-
18
-
-
0037064106
-
Ligandindependent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells
-
Ueda T, Mawji NR, Bruchovsky N et al. Ligandindependent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells. J Biol Chem 2002;277:38087-38094
-
(2002)
J Biol Chem
, vol.277
, pp. 38087-38094
-
-
Ueda, T.1
Mawji, N.R.2
Bruchovsky, N.3
-
19
-
-
46949098184
-
Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation
-
Seaton A, Scullin P, Maxwell PJ et al. Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation. Carcinogenesis 2008;29:1148-1156
-
(2008)
Carcinogenesis
, vol.29
, pp. 1148-1156
-
-
Seaton, A.1
Scullin, P.2
Maxwell, P.J.3
-
20
-
-
84878179644
-
Transforming growth factor beta in prostate cancer: Cellular effects and basic molecular mechanisms
-
Stope MB, Ronnau C, Schubert T et al. Transforming growth factor beta in prostate cancer: Cellular effects and basic molecular mechanisms. Urologe A 2013;52:378-383
-
(2013)
Urologe A
, vol.52
, pp. 378-383
-
-
Stope, M.B.1
Ronnau, C.2
Schubert, T.3
-
21
-
-
54849435425
-
Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol
-
Dillard PR, Lin MF, Khan SA. Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol. Mol Cell Endocrinol 2008; 295:115-120
-
(2008)
Mol Cell Endocrinol
, vol.295
, pp. 115-120
-
-
Dillard, P.R.1
Lin, M.F.2
Khan, S.A.3
-
22
-
-
76149137405
-
Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model
-
Leon CG, Locke JA, Adomat HH et al. Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model. Prostate 2010;70:390-400
-
(2010)
Prostate
, vol.70
, pp. 390-400
-
-
Leon, C.G.1
Locke, J.A.2
Adomat, H.H.3
-
23
-
-
79959312739
-
A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
-
Hu R, Isaacs WB, Luo J. A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities. Prostate 2011;71:1656-1667
-
(2011)
Prostate
, vol.71
, pp. 1656-1667
-
-
Hu, R.1
Isaacs, W.B.2
Luo, J.3
-
24
-
-
84863979005
-
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer
-
Hu R, Lu C, Mostaghel EA et al. Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer Res 2012;72:3457-3462
-
(2012)
Cancer Res
, vol.72
, pp. 3457-3462
-
-
Hu, R.1
Lu, C.2
Mostaghel, E.A.3
-
25
-
-
78049280194
-
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
-
Watson PA, Chen YF, Balbas MD et al. Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor. Proc Natl Acad Sci U S A 2010;107:16759-16765
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16759-16765
-
-
Watson, P.A.1
Chen, Y.F.2
Balbas, M.D.3
-
26
-
-
10844235652
-
Androgen-independent prostate cancer is a heterogeneous group of diseases: Lessons from a rapid autopsy program
-
Shah RB, Mehra R, Chinnaiyan AM et al. Androgen-independent prostate cancer is a heterogeneous group of diseases: Lessons from a rapid autopsy program. Cancer Res 2004;64:9209-9216
-
(2004)
Cancer Res
, vol.64
, pp. 9209-9216
-
-
Shah, R.B.1
Mehra, R.2
Chinnaiyan, A.M.3
-
27
-
-
84872732113
-
DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases
-
Aryee MJ, Liu W, Engelmann JC et al. DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases. Sci TranslMed 2013;5:169-170
-
(2013)
Sci TranslMed
, vol.5
, pp. 169-170
-
-
Aryee, M.J.1
Liu, W.2
Engelmann, J.C.3
-
29
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
de Bono JS, Oudard S, OzgurogluMet al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial. Lancet 2010;376:1147-1154
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
de Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
-
30
-
-
84866948935
-
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: Final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
-
Fizazi K, Scher HI, Molina A et al. Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol 2012;13:983-992
-
(2012)
Lancet Oncol
, vol.13
, pp. 983-992
-
-
Fizazi, K.1
Scher, H.I.2
Molina, A.3
-
31
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med 2011;364:1995-2005
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
de Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
-
32
-
-
84865834363
-
Updated analysis of the phase III, double-blind, randomized, multinational study of radium-223 chloride in castration-resistant prostate cancer (CRPC) patients with bone metastases (ALSYMPCA)
-
Parker C, Nilsson S, Heinrich D et al. Updated analysis of the phase III, double-blind, randomized, multinational study of radium-223 chloride in castration-resistant prostate cancer (CRPC) patients with bone metastases (ALSYMPCA). J Clin Oncol 2012;30:LBA4512
-
(2012)
J Clin Oncol
, vol.30
-
-
Parker, C.1
Nilsson, S.2
Heinrich, D.3
-
33
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, de WR, Berry WR et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004; 351:1502-1512
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
De, W.R.2
Berry, W.R.3
-
34
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP, Tangen CM, HussainMHet al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004;351:1513-1520
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
-
35
-
-
38349167518
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: Updated survival in the TAX 327 study
-
Berthold DR, Pond GR, Soban F et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: Updated survival in the TAX 327 study. J Clin Oncol 2008;26:242-245
-
(2008)
J Clin Oncol
, vol.26
, pp. 242-245
-
-
Berthold, D.R.1
Pond, G.R.2
Soban, F.3
-
36
-
-
84872078210
-
Abiraterone in metastatic prostate cancer without previous chemotherapy
-
Ryan CJ, Smith MR, de Bono JS et al. Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med 2013;368:138-148
-
(2013)
N Engl J Med
, vol.368
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
de Bono, J.S.3
-
37
-
-
84878190220
-
Updated interim analysis of COU-AA-302, a randomized phase III study of abiraterone acetate in patients wiht metastatic castration-resistant prostate cancer without prior chemotherapy
-
Rathkopf DE, Smith MR, de Bono JS et al. Updated interim analysis of COU-AA-302, a randomized phase III study of abiraterone acetate in patients wiht metastatic castration-resistant prostate cancer without prior chemotherapy. J Clin Oncol 2013;31:5
-
(2013)
J Clin Oncol
, vol.31
, pp. 5
-
-
Rathkopf, D.E.1
Smith, M.R.2
de Bono, J.S.3
-
38
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010;363:411-422
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
39
-
-
84867594749
-
Primary, secondary and quality of life endpoint results from the phase III AFFIRM study of MDV3100, an androgen receptor signalling inhibitor
-
de Bono JS, Fizazi K, Saad F et al. Primary, secondary and quality of life endpoint results from the phase III AFFIRM study of MDV3100, an androgen receptor signalling inhibitor. J Clin Oncol 2012;30: 4519
-
(2012)
J Clin Oncol
, vol.30
, pp. 4519
-
-
de Bono, J.S.1
Fizazi, K.2
Saad, F.3
-
40
-
-
84865336863
-
Optimizing the care of patients withadvancedprostate cancer in the UK: Current challenges and future opportunities
-
Payne H, Bahl A, Mason M, Troup J, De BJ. Optimizing the care of patients withadvancedprostate cancer in the UK: Current challenges and future opportunities. BJU Int 2012;110:658-667
-
(2012)
BJU Int
, vol.110
, pp. 658-667
-
-
Payne, H.1
Bahl, A.2
Mason, M.3
Troup, J.4
De, B.J.5
-
41
-
-
84875237289
-
Optimizing the management of prostate cancer in senior adults: Call to action
-
Fitzpatrick JM. Optimizing the management of prostate cancer in senior adults: call to action. The Oncologist 2012;17 (Suppl 1):1-3
-
(2012)
The Oncologist
, vol.17
, Issue.SUPPL. 1
, pp. 1-3
-
-
Fitzpatrick, J.M.1
-
42
-
-
27144450156
-
Predictive factors for skeletal complications in hormone-refractory prostate cancer patients with metastatic bone disease
-
Berruti A, Tucci M, Mosca A et al. Predictive factors for skeletal complications in hormone-refractory prostate cancer patients with metastatic bone disease. Br J Cancer 2005;93:633-638
-
(2005)
Br J Cancer
, vol.93
, pp. 633-638
-
-
Berruti, A.1
Tucci, M.2
Mosca, A.3
-
43
-
-
79952253824
-
EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer
-
Mottet N, Bellmunt J, BollaMet al. EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer. Eur Urol 2011;59:572-583
-
(2011)
Eur Urol
, vol.59
, pp. 572-583
-
-
Mottet, N.1
Bellmunt, J.2
Bolla, M.3
-
44
-
-
84878189292
-
-
U.S. Food and Drug Administration
-
U.S. Food and Drug Administration. Clinical team leader review memo regarding SGE patient representative: Provenge, April 26, 2010. Available at http://www.fda.gov/BiologicsBloodVaccines/CellularGeneTherapyProducts/ApprovedProducts/ ucm213559.htm. Accessed April 5, 2013
-
(2013)
Clinical Team Leader Review Memo Regarding SGE Patient Representative: Provenge
-
-
-
45
-
-
84857397717
-
Interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer
-
Huber ML, Haynes L, Parker C et al. Interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer. J Natl Cancer Inst 2012;104:273-279
-
(2012)
J Natl Cancer Inst
, vol.104
, pp. 273-279
-
-
Huber, M.L.1
Haynes, L.2
Parker, C.3
-
47
-
-
84857658331
-
The role of sipuleucel-T in therapy for castration-resistant prostate cancer: A critical analysis of the literature
-
Sonpavde G, Di LG, Higano CS et al. The role of sipuleucel-T in therapy for castration-resistant prostate cancer: A critical analysis of the literature. Eur Urol 2012;61:639-647
-
(2012)
Eur Urol
, vol.61
, pp. 639-647
-
-
Sonpavde, G.1
Di, L.G.2
Higano, C.S.3
-
48
-
-
79952111427
-
Implications of bone metastases and the benefits of bone-targeted therapy
-
Lipton A. Implications of bone metastases and the benefits of bone-targeted therapy. Semin Oncol 2010;37(SUPPL.2):S15-S29
-
(2010)
Semin Oncol
, vol.37
, Issue.SUPPL. 2
-
-
Lipton, A.1
-
49
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy GR. Metastasis to bone: Causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002;2:584-593
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
50
-
-
0032800631
-
Mechanisms, hypotheses and questions regarding prostate cancer micrometastases to bone
-
Lange PH, Vessella RL. Mechanisms, hypotheses and questions regarding prostate cancer micrometastases to bone. Cancer Metastasis Rev 1998; 17:331-336
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 331-336
-
-
Lange, P.H.1
Vessella, R.L.2
-
51
-
-
0037009822
-
Arandomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma
-
Saad F, Gleason DM, Murray R et al. Arandomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma. J Natl Cancer Inst 2002;94:1458-1468
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1458-1468
-
-
Saad, F.1
Gleason, D.M.2
Murray, R.3
-
52
-
-
2942518111
-
Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
-
Saad F, Gleason DM, Murray R et al. Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J Natl Cancer Inst 2004;96:879-882
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 879-882
-
-
Saad, F.1
Gleason, D.M.2
Murray, R.3
-
53
-
-
0034659773
-
Cellular and molecular mechanisms of action of bisphosphonates
-
Rogers MJ, Gordon S, Benford HL et al. Cellular and molecular mechanisms of action of bisphosphonates. Cancer 2000;88:2961-2978
-
(2000)
Cancer
, vol.88
, pp. 2961-2978
-
-
Rogers, M.J.1
Gordon, S.2
Benford, H.L.3
-
54
-
-
84859119876
-
Bone-modifying agents in the treatment of bone metastases in patients with advancedgenitourinary malignancies:Afocusonzoledronic acid
-
Aapro M, Saad F. Bone-modifying agents in the treatment of bone metastases in patients with advancedgenitourinary malignancies:Afocusonzoledronic acid. Ther Adv Urol 2012;4:85-101
-
(2012)
Ther Adv Urol
, vol.4
, pp. 85-101
-
-
Aapro, M.1
Saad, F.2
-
55
-
-
84855516339
-
Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: Results of a phase 3, randomised, placebo-controlled trial
-
Smith MR, Saad F, Coleman R et al. Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: Results of a phase 3, randomised, placebo-controlled trial. Lancet 2012;379:39-46
-
(2012)
Lancet
, vol.379
, pp. 39-46
-
-
Smith, M.R.1
Saad, F.2
Coleman, R.3
-
56
-
-
79952360832
-
Denosumab versus zoledronic acid for treatment ofbonemetastases inmenwith castration-resistant prostate cancer: A randomised, double-blind study
-
Fizazi K, CarducciM,SmithMet al.Denosumab versus zoledronic acid for treatment ofbonemetastases inmenwith castration-resistant prostate cancer: A randomised, double-blind study. Lancet 2011;377:813-822
-
(2011)
Lancet
, vol.377
, pp. 813-822
-
-
Fizazi, K.1
Carducci, M.2
Smith, M.3
-
57
-
-
84878197268
-
Updated analysis of radium-223 dichloride (RA-223) impact on skeletal-related events (SRE) in patients with castration-resistant prostate cancer (CRPC) andbonemetastasesfromthephaseIIIrandomized trial (ALSYMPCA)
-
Vogelzang NJ, Parker C, Nilsson S et al. Updated analysis of radium-223 dichloride (RA-223) impact on skeletal-related events (SRE) in patients with castration-resistant prostate cancer (CRPC) andbonemetastasesfromthephaseIIIrandomized trial (ALSYMPCA). J Clin Oncol 2013;31:11
-
(2013)
J Clin Oncol
, vol.31
, pp. 11
-
-
Vogelzang, N.J.1
Parker, C.2
Nilsson, S.3
-
58
-
-
82355163158
-
Novel therapeutic strategies for metastatic prostate cancer in the post-docetaxel setting
-
Sartor O, Michels RM, Massard C et al. Novel therapeutic strategies for metastatic prostate cancer in the post-docetaxel setting. The Oncologist 2011;16:1487-1497
-
(2011)
The Oncologist
, vol.16
, pp. 1487-1497
-
-
Sartor, O.1
Michels, R.M.2
Massard, C.3
-
59
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 2008;8: 592-603
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
60
-
-
65249122512
-
Novel therapeutic inhibitors of the c-Met signaling pathway in cancer
-
Eder JP, VandeWoudeGF, Boerner SA et al. Novel therapeutic inhibitors of the c-Met signaling pathway in cancer. ClinCancerRes2009;15:2207-2214
-
ClinCancerRes2009
, vol.15
, pp. 2207-2214
-
-
Eder, J.P.1
VandeWoude, G.F.2
Boerner, S.A.3
-
61
-
-
80053571555
-
Cabozantinib (XL184) in metastatic castration-resistant prostate cancer (mCRPC): Results from a phase II randomized discontinuation trial
-
Hussain M, Smith MR, Sweeney C et al. Cabozantinib (XL184) in metastatic castration-resistant prostate cancer (mCRPC): Results from a phase II randomized discontinuation trial. J Clin Oncol 2011; 29:4516
-
(2011)
J Clin Oncol
, vol.29
, pp. 4516
-
-
Hussain, M.1
Smith, M.R.2
Sweeney, C.3
-
62
-
-
84867603148
-
Chemotherapy-pretreated metastatic castration-resistant prostate cancer: Results from a phase II nonrandomized expansion cohort
-
Cabozantinib (XL184)
-
Smith MR, Sweeney C, Rathkopf D.E. et al. Cabozantinib (XL184)in chemotherapy-pretreated metastatic castration-resistant prostate cancer: Results from a phase II nonrandomized expansion cohort. J Clin Oncol 2012;30:4513
-
(2012)
J Clin Oncol
, vol.30
, pp. 4513
-
-
Smith, M.R.1
Sweeney, C.2
Rathkopf, D.E.3
-
63
-
-
84876281035
-
Cabozantinib (XL184) at 40 mg in patients with metastatic castration-resistant prostate cancer: Results of a phase 2 non-randomized expansion cohort (NRE)
-
Abstract 8970
-
de Bono JS, Smith MR, Rathkopf DE et al. Cabozantinib (XL184) at 40 mg in patients with metastatic castration-resistant prostate cancer: Results of a phase 2 non-randomized expansion cohort (NRE). Ann Oncol 2012;23:Abstract 8970
-
(2012)
Ann Oncol
, vol.23
-
-
de Bono, J.S.1
Smith, M.R.2
Rathkopf, D.E.3
-
64
-
-
84856406031
-
Biomarkers in the management and treatment of men with metastatic castration-resistant prostate cancer
-
Armstrong AJ, Eisenberger MA, Halabi S et al. Biomarkers in the management and treatment of men with metastatic castration-resistant prostate cancer. Eur Urol 2012;61:549-559
-
(2012)
Eur Urol
, vol.61
, pp. 549-559
-
-
Armstrong, A.J.1
Eisenberger, M.A.2
Halabi, S.3
-
65
-
-
77949667760
-
Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents
-
Dancey JE, Dobbin KK, Groshen S et al. Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents. Clin Cancer Res 2010;16:1745-1755
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1745-1755
-
-
Dancey, J.E.1
Dobbin, K.K.2
Groshen, S.3
-
66
-
-
33750737312
-
Activation of the PKB/Akt pathway in histological benign prostatic tissue adjacent to the primary malignant lesions
-
Merseburger AS, Hennenlotter J, Simon P et al. Activation of the PKB/Akt pathway in histological benign prostatic tissue adjacent to the primary malignant lesions. Oncol Rep 2006;16:79-83
-
(2006)
Oncol Rep
, vol.16
, pp. 79-83
-
-
Merseburger, A.S.1
Hennenlotter, J.2
Simon, P.3
-
67
-
-
84874787799
-
Cabozantinib in patients with advanced prostate cancer: Results of a phase II randomized discontinuation trial
-
Smith DC, Smith MR, Sweeney C et al. Cabozantinib in patients with advanced prostate cancer: Results of a phase II randomized discontinuation trial. J Clin Oncol 2013;31:412-419
-
(2013)
J Clin Oncol
, vol.31
, pp. 412-419
-
-
Smith, D.C.1
Smith, M.R.2
Sweeney, C.3
-
68
-
-
0030811134
-
Small cell anaplastic carcinoma of the prostate: Seven new cases, review of the literature, and discussion of a therapeutic strategy
-
Rubenstein JH, Katin MJ, Mangano MM et al. Small cell anaplastic carcinoma of the prostate: Seven new cases, review of the literature, and discussion of a therapeutic strategy. Am J Clin Oncol 1997;20:376-380
-
(1997)
Am J Clin Oncol
, vol.20
, pp. 376-380
-
-
Rubenstein, J.H.1
Katin, M.J.2
Mangano, M.M.3
-
69
-
-
36148967358
-
Prostate-specific antigen doubling time before onset of chemotherapy as a predictor of survival for hormonerefractory prostate cancer patients
-
Oudard S, Banu E, Scotte F et al. Prostate-specific antigen doubling time before onset of chemotherapy as a predictor of survival for hormonerefractory prostate cancer patients. Ann Oncol 2007;18:1828-1833
-
(2007)
Ann Oncol
, vol.18
, pp. 1828-1833
-
-
Oudard, S.1
Banu, E.2
Scotte, F.3
-
70
-
-
84867139766
-
Prostate-specific antigen kinetics as a surrogate endpoint in clinical trials of metastatic castration-resistant prostate cancer: Areview
-
Colloca G. Prostate-specific antigen kinetics as a surrogate endpoint in clinical trials of metastatic castration-resistant prostate cancer:Areview. Cancer Treat Rev 2012;38:1020-1026
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 1020-1026
-
-
Colloca, G.1
-
71
-
-
41949104346
-
Design and endpoints of clinical trials for patients with progressive prostate cancerandcastrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
-
Scher HI, Halabi S, Tannock I et al. Design and endpoints of clinical trials for patients with progressive prostate cancerandcastrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group. J Clin Oncol 2008;26: 1148-1159
-
(2008)
J Clin Oncol
, vol.26
, pp. 1148-1159
-
-
Scher, H.I.1
Halabi, S.2
Tannock, I.3
-
72
-
-
84866745304
-
Serum alkaline phosphatase changes predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy
-
Sonpavde G, Pond GR, Berry WR et al. Serum alkaline phosphatase changes predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy. Urol Oncol 2012;30:607-613
-
(2012)
Urol Oncol
, vol.30
, pp. 607-613
-
-
Sonpavde, G.1
Pond, G.R.2
Berry, W.R.3
-
73
-
-
24644479228
-
Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid
-
Coleman RE, Major P, Lipton A et al. Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid. J Clin Oncol 2005; 23:4925-4935
-
(2005)
J Clin Oncol
, vol.23
, pp. 4925-4935
-
-
Coleman, R.E.1
Major, P.2
Lipton, A.3
-
74
-
-
58149165081
-
Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer
-
deBono JS, Scher HI, Montgomery RB et al. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin Cancer Res 2008;14:6302-6309
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6302-6309
-
-
Debono, J.S.1
Scher, H.I.2
Montgomery, R.B.3
-
75
-
-
84870050058
-
Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer
-
Miyamoto DT, Lee RJ, Stott SL et al. Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer. Cancer Discov 2012;2:995-1003
-
(2012)
Cancer Discov
, vol.2
, pp. 995-1003
-
-
Miyamoto, D.T.1
Lee, R.J.2
Stott, S.L.3
-
76
-
-
0038514138
-
Prognostic model for predicting survival inmenwith hormonerefractory metastatic prostate cancer
-
Halabi S, Small EJ, KantoffPWet al. Prognostic model for predicting survival inmenwith hormonerefractory metastatic prostate cancer. J Clin Oncol 2003;21:1232-1237
-
(2003)
J Clin Oncol
, vol.21
, pp. 1232-1237
-
-
Halabi, S.1
Small, E.J.2
Kantoff, P.W.3
-
77
-
-
35948933892
-
A contemporary prognostic nomogram for men with hormone-refractory metastatic prostate cancer: A TAX327 study analysis
-
Armstrong AJ, Garrett-Mayer ES, Yang YC et al. A contemporary prognostic nomogram for men with hormone-refractory metastatic prostate cancer: A TAX327 study analysis. Clin Cancer Res 2007; 13:6396-6403
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6396-6403
-
-
Armstrong, A.J.1
Garrett-Mayer, E.S.2
Yang, Y.C.3
-
78
-
-
74949112755
-
Prediction of survival following first-line chemotherapy inmenwith castration-resistant metastatic prostate cancer
-
Armstrong AJ, Garrett-Mayer E, de WR et al. Prediction of survival following first-line chemotherapy inmenwith castration-resistant metastatic prostate cancer. Clin Cancer Res 2010;16:203-211
-
(2010)
Clin Cancer Res
, vol.16
, pp. 203-211
-
-
Armstrong, A.J.1
Garrett-Mayer, E.2
De, W.R.3
-
79
-
-
80455135119
-
Prognostic impact of C-reactive protein for determining overall survival of patients with castration-resistant prostate cancer treated with docetaxel
-
Ito M, Saito K, Yasuda Y et al. Prognostic impact of C-reactive protein for determining overall survival of patients with castration-resistant prostate cancer treated with docetaxel. Urology 2011;78: 1131-1135
-
(2011)
Urology
, vol.78
, pp. 1131-1135
-
-
Ito, M.1
Saito, K.2
Yasuda, Y.3
-
80
-
-
45149115061
-
Chemotherapy for advanced prostate cancer: 25 years later
-
Logothetis CJ, Millikan R. Chemotherapy for advanced prostate cancer: 25 years later. J Clin Oncol 2008;26:2423-2424
-
(2008)
J Clin Oncol
, vol.26
, pp. 2423-2424
-
-
Logothetis, C.J.1
Millikan, R.2
-
81
-
-
33644675811
-
Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis
-
Scher HI, Sawyers CL. Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis. J Clin Oncol 2005;23:8253-8261
-
(2005)
J Clin Oncol
, vol.23
, pp. 8253-8261
-
-
Scher, H.I.1
Sawyers, C.L.2
-
82
-
-
84870165370
-
New perspectives in the therapy of castration resistant prostate cancer
-
Rescigno P, Buonerba C, Bellmunt J et al. New perspectives in the therapy of castration resistant prostate cancer. Curr Drug Targets 2012;13:1676-1686
-
(2012)
Curr Drug Targets
, vol.13
, pp. 1676-1686
-
-
Rescigno, P.1
Buonerba, C.2
Bellmunt, J.3
-
83
-
-
84857555393
-
Molecular states underlying androgen receptor activation:Aframework for therapeutics targeting androgen signaling in prostate cancer
-
Nelson PS. Molecular states underlying androgen receptor activation:Aframework for therapeutics targeting androgen signaling in prostate cancer. J Clin Oncol 2012;30:644-646
-
(2012)
J Clin Oncol
, vol.30
, pp. 644-646
-
-
Nelson, P.S.1
-
84
-
-
84863393126
-
Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone
-
Efstathiou E, Titus M, Tsavachidou D et al. Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone. J Clin Oncol 2012;30:637-643
-
(2012)
J Clin Oncol
, vol.30
, pp. 637-643
-
-
Efstathiou, E.1
Titus, M.2
Tsavachidou, D.3
-
86
-
-
84872523675
-
Endocrine therapy in prostate cancer: Time for reappraisal of risks, benefits and cost-effectiveness?
-
Bourke L, Kirkbride P, Hooper R et al. Endocrine therapy in prostate cancer: Time for reappraisal of risks, benefits and cost-effectiveness? Br J Cancer 2013;108:9-13
-
(2013)
Br J Cancer
, vol.108
, pp. 9-13
-
-
Bourke, L.1
Kirkbride, P.2
Hooper, R.3
-
87
-
-
80053085982
-
End points and outcomes in castration-resistant prostate cancer: From clinical trials to clinical practice
-
Scher HI, Morris MJ, Basch E et al. End points and outcomes in castration-resistant prostate cancer: From clinical trials to clinical practice. J Clin Oncol 2011;29:3695-3704
-
(2011)
J Clin Oncol
, vol.29
, pp. 3695-3704
-
-
Scher, H.I.1
Morris, M.J.2
Basch, E.3
-
88
-
-
84863717956
-
Urologists and oncologists: Adapting to a new treatment paradigm in castration-resistant prostate cancer (CRPC)
-
Sartor AO, Fitzpatrick JM. Urologists and oncologists: Adapting to a new treatment paradigm in castration-resistant prostate cancer (CRPC). BJU Int 2012;110:328-335
-
(2012)
BJU Int
, vol.110
, pp. 328-335
-
-
Sartor, A.O.1
Fitzpatrick, J.M.2
-
89
-
-
84857886708
-
Multiple rechallenges for castration-resistant prostate cancer patients responding to firstline docetaxel: Assessment of clinical outcomes and predictive factors
-
Caffo O, Pappagallo G, Brugnara S et al. Multiple rechallenges for castration-resistant prostate cancer patients responding to firstline docetaxel: Assessment of clinical outcomes and predictive factors. Urology 2012;79:644-649.
-
(2012)
Urology
, vol.79
, pp. 644-649
-
-
Caffo, O.1
Pappagallo, G.2
Brugnara, S.3
-
90
-
-
77953289240
-
The interval from the last cycle of docetaxel-based chemotherapy to progression is associated with the efficacy of subsequent docetaxel in patients with prostate cancer
-
Loriot Y, Massard C, Gross-Goupil M et al. The interval from the last cycle of docetaxel-based chemotherapy to progression is associated with the efficacy of subsequent docetaxel in patients with prostate cancer. Eur J Cancer 2010;46:1770-1772
-
(2010)
Eur J Cancer
, vol.46
, pp. 1770-1772
-
-
Loriot, Y.1
Massard, C.2
Gross-Goupil, M.3
-
91
-
-
84876448717
-
Rational indication for docetaxel rechallenge in metastatic castration-resistant prostate cancer
-
Heck MM, Thalgott M, Retz M et al. Rational indication for docetaxel rechallenge in metastatic castration-resistant prostate cancer. BJU Int 2012; 110:E635-E640
-
(2012)
BJU Int
, vol.110
-
-
Heck, M.M.1
Thalgott, M.2
Retz, M.3
-
92
-
-
84856771905
-
Optimizing outcomes of advanced prostate cancer: Drug sequencing and novel therapeutic approaches
-
Crawford ED, Flaig TW. Optimizing outcomes of advanced prostate cancer: Drug sequencing and novel therapeutic approaches. Oncology (Williston Park) 2012;26:70-77
-
(2012)
Oncology (Williston Park)
, vol.26
, pp. 70-77
-
-
Crawford, E.D.1
Flaig, T.W.2
-
93
-
-
77953265615
-
Management of prostate cancer in older men: Recommendations of a working group of the International Society of Geriatric Oncology
-
Droz JP, Balducci L, Bolla M et al. Management of prostate cancer in older men: Recommendations of a working group of the International Society of Geriatric Oncology. BJU Int 2010;106:462-469
-
(2010)
BJU Int
, vol.106
, pp. 462-469
-
-
Droz, J.P.1
Balducci, L.2
Bolla, M.3
-
94
-
-
80755182165
-
Effect of abiraterone acetate (AA) on pain control and skeletal-related events (SRE) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) post docetaxel (D): Results from the COUAA-301 phase III study
-
Logothetis CJ, de Bono JS, Molina A et al. Effect of abiraterone acetate (AA) on pain control and skeletal-related events (SRE) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) post docetaxel (D): Results from the COUAA-301 phase III study. J Clin Oncol 2011;29:4520
-
(2011)
J Clin Oncol
, vol.29
, pp. 4520
-
-
Logothetis, C.J.1
de Bono, J.S.2
Molina, A.3
-
95
-
-
84858706749
-
A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer
-
Nilsson S, Strang P, Aksnes AK et al. A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer. Eur J Cancer 2012;48:678-686
-
(2012)
Eur J Cancer
, vol.48
, pp. 678-686
-
-
Nilsson, S.1
Strang, P.2
Aksnes, A.K.3
-
96
-
-
65549099731
-
Phase II study of sunitinib in men with advanced prostate cancer
-
Dror MM, Regan MM, Oh WK et al. Phase II study of sunitinib in men with advanced prostate cancer. Ann Oncol 2009;20:913-920
-
(2009)
Ann Oncol
, vol.20
, pp. 913-920
-
-
Dror, M.M.1
Regan, M.M.2
Oh, W.K.3
-
97
-
-
84866889249
-
Effects of sorafenib on C-terminally truncated androgen receptor variants in human prostate cancer cells
-
Zengerling F, Streicher W, Schrader AJ et al. Effects of sorafenib on C-terminally truncated androgen receptor variants in human prostate cancer cells. Int J Mol Sci 2012;13:11530-11542
-
(2012)
Int J Mol Sci
, vol.13
, pp. 11530-11542
-
-
Zengerling, F.1
Streicher, W.2
Schrader, A.J.3
-
98
-
-
4644250900
-
Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer
-
Oh WK, Kantoff PW, Weinberg V et al. Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer. J Clin Oncol 2004;22:3705-3712
-
(2004)
J Clin Oncol
, vol.22
, pp. 3705-3712
-
-
Oh, W.K.1
Kantoff, P.W.2
Weinberg, V.3
-
99
-
-
70449092017
-
The mechanism of action of estrogen in castration-resistant prostate cancer: Clues from hormone levels
-
Aggarwal R, Weinberg V, Small EJ et al. The mechanism of action of estrogen in castration-resistant prostate cancer: Clues from hormone levels. Clin Genitourin Cancer 2009;7:E71-E76
-
(2009)
Clin Genitourin Cancer
, vol.7
-
-
Aggarwal, R.1
Weinberg, V.2
Small, E.J.3
-
100
-
-
80052468423
-
RandomizedphaseII trial of Custirsen (OGX-011) in combination with docetaxel or mitoxantrone as second-line therapy in patients with metastatic castrate-resistant prostate cancer progressing after first-line docetaxel: CUOG trial P-06c
-
Saad F, Hotte S, North S. et al. RandomizedphaseII trial of Custirsen (OGX-011) in combination with docetaxel or mitoxantrone as second-line therapy in patients with metastatic castrate-resistant prostate cancer progressing after first-line docetaxel: CUOG trial P-06c. ClinCancerRes2011;17:5765-5773
-
ClinCancerRes2011
, vol.17
, pp. 5765-5773
-
-
Saad, F.1
Hotte, S.2
North, S.3
-
101
-
-
84874116175
-
T cell profiling reveals high CD4(+)CTLA-4 (+) T cell frequency as dominant predictor for survival after Prostate GVAX/ipilimumab treatment
-
Santegoets SJ, Stam AG, Lougheed SM et al. T cell profiling reveals high CD4(+)CTLA-4 (+) T cell frequency as dominant predictor for survival after Prostate GVAX/ipilimumab treatment. Cancer Immunol Immunother 2013;62:245-256
-
(2013)
Cancer Immunol Immunother
, vol.62
, pp. 245-256
-
-
Santegoets, S.J.1
Stam, A.G.2
Lougheed, S.M.3
-
102
-
-
77949895922
-
Overall survival analysis of a phase II randomized controlled trial ofaPoxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer
-
Kantoff PW, Schuetz TJ, Blumenstein BA et al. Overall survival analysis of a phase II randomized controlled trial ofaPoxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol 2010;28:1099-1105
-
(2010)
J Clin Oncol
, vol.28
, pp. 1099-1105
-
-
Kantoff, P.W.1
Schuetz, T.J.2
Blumenstein, B.A.3
-
103
-
-
84878167537
-
Aphase I/II study of safety and efficacy of orteronel (TAK-700), an oral, investigational, nonsteroidal 17,20-lyase inhibitor, with docetaxel and prednisone (DP) in metastatic castration-resistant prostate cancer (mCRPC): Updated phase II results
-
Petrylak D, Gandhi JG, Clark WR et al. Aphase I/II study of safety and efficacy of orteronel (TAK-700), an oral, investigational, nonsteroidal 17,20-lyase inhibitor, with docetaxel and prednisone (DP) in metastatic castration-resistant prostate cancer (mCRPC): Updated phase II results. J Clin Oncol 2013;31:59
-
(2013)
J Clin Oncol
, vol.31
, pp. 59
-
-
Petrylak, D.1
Gandhi, J.G.2
Clark, W.R.3
-
104
-
-
84863230424
-
ARN-509: A novel antiandrogen for prostate cancer treatment
-
Clegg NJ, Wongvipat J, Joseph JD et al. ARN-509: A novel antiandrogen for prostate cancer treatment. Cancer Res 2012;72:1494-1503
-
(2012)
Cancer Res
, vol.72
, pp. 1494-1503
-
-
Clegg, N.J.1
Wongvipat, J.2
Joseph, J.D.3
-
105
-
-
84878170293
-
ODM-21, a new generation androgen receptor inhibitor for castration-resistant prostate cancer: Preclinical and phase I data
-
Fizazi K, Massard C, James ND et al. ODM-21, a new generation androgen receptor inhibitor for castration-resistant prostate cancer: Preclinical and phase I data. J Clin Oncol 2013;31:65
-
(2013)
J Clin Oncol
, vol.31
, pp. 65
-
-
Fizazi, K.1
Massard, C.2
James, N.D.3
-
106
-
-
84860348682
-
Lenalidomide enhances the anti-prostate cancer activity of docetaxel in vitroandin vivo
-
Henry JY, Lu L, Adams M et al. Lenalidomide enhances the anti-prostate cancer activity of docetaxel in vitroandin vivo. Prostate2012;72:856-867
-
Prostate2012
, vol.72
, pp. 856-867
-
-
Henry, J.Y.1
Lu, L.2
Adams, M.3
-
107
-
-
78049477140
-
Lenalidomide in nonmetastatic biochemically relapsed prostate cancer: Results of a phase I/II doubleblinded, randomized study
-
Keizman D, Zahurak M, Sinibaldi V et al. Lenalidomide in nonmetastatic biochemically relapsed prostate cancer: Results of a phase I/II doubleblinded, randomized study. Clin Cancer Res 2010; 16:5269-5276
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5269-5276
-
-
Keizman, D.1
Zahurak, M.2
Sinibaldi, V.3
-
108
-
-
67049171301
-
Phase I study of oral lenalidomide in patients with refractory metastatic cancer
-
Dahut WL, Aragon-Ching JB, Woo S et al. Phase I study of oral lenalidomide in patients with refractory metastatic cancer. J Clin Pharmacol 2009;49:650-660
-
(2009)
J Clin Pharmacol
, vol.49
, pp. 650-660
-
-
Dahut, W.L.1
Aragon-Ching, J.B.2
Woo, S.3
-
109
-
-
84865418670
-
Phase II study of first-line sagopilone plus prednisone in patients with castration-resistant prostate cancer: A phase II study of the Department of Defense Prostate Cancer Clinical Trials Consortium
-
Beer TM, Smith DC, Hussain A et al. Phase II study of first-line sagopilone plus prednisone in patients with castration-resistant prostate cancer: A phase II study of the Department of Defense Prostate Cancer Clinical Trials Consortium. Br J Cancer 2012;107:808-813
-
(2012)
Br J Cancer
, vol.107
, pp. 808-813
-
-
Beer, T.M.1
Smith, D.C.2
Hussain, A.3
-
110
-
-
84876283322
-
Overall survival (OS) and safety of dasatinib/docetaxel versus docetaxel in patients with metastatic castration-resistant prostate cancer (mCRPC): Results from the randomized phase III READYtrial
-
Araujo JC, Trudel GC, Saad F et al. Overall survival (OS) and safety of dasatinib/docetaxel versus docetaxel in patients with metastatic castration-resistant prostate cancer (mCRPC): Results from the randomized phase III READYtrial. J ClinOncol 2013;31:LBA8
-
(2013)
J ClinOncol
, vol.31
-
-
Araujo, J.C.1
Trudel, G.C.2
Saad, F.3
-
111
-
-
84882450996
-
Phase III, randomized, placebo-controlled study of once-daily oral zibotentan (ZD4054) in patients with non-metastatic castration-resistant prostate cancer
-
10.10381pcan.2013.2
-
Miller K, Moul JW, Gleave M et al. Phase III, randomized, placebo-controlled study of once-daily oral zibotentan (ZD4054) in patients with non-metastatic castration-resistant prostate cancer. Prostate Cancer Prostatic Dis 2013 Feb5; doi:10.10381pcan.2013.2
-
Prostate Cancer Prostatic Dis
, Issue.2013
-
-
Miller, K.1
Moul, J.W.2
Gleave, M.3
-
112
-
-
73949098659
-
Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: The SPARC trial
-
Sternberg CN, Petrylak DP, Sartor O et al. Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: The SPARC trial. J Clin Oncol 2009;27:5431-5438
-
(2009)
J Clin Oncol
, vol.27
, pp. 5431-5438
-
-
Sternberg, C.N.1
Petrylak, D.P.2
Sartor, O.3
-
113
-
-
84861690508
-
Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401
-
Kelly WK, Halabi S, Carducci M. et al. Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401. J Clin Oncol 2012;30:1534-1540
-
(2012)
J Clin Oncol
, vol.30
, pp. 1534-1540
-
-
Kelly, W.K.1
Halabi, S.2
Carducci, M.3
-
114
-
-
55549112219
-
Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer
-
Nelson JB, Love W, Chin JL et al. Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer. Cancer 2008;113:2478-2487
-
(2008)
Cancer
, vol.113
, pp. 2478-2487
-
-
Nelson, J.B.1
Love, W.2
Chin, J.L.3
-
115
-
-
68549135290
-
Integrated data from 2 randomized, doubleblind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
Migano CS, Schellhammer PF, Small EJ et al. Integrated data from 2 randomized, doubleblind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 2009;115:3670-3679.
-
(2009)
Cancer
, vol.115
, pp. 3670-3679
-
-
Migano, C.S.1
Schellhammer, P.F.2
Small, E.J.3
|