메뉴 건너뛰기




Volumn 13, Issue 9, 2012, Pages 11530-11542

Receptor variants in human prostate cancer cells

Author keywords

Castration resistant prostate cancer; Sorafenib; Truncated androgen receptor variants

Indexed keywords

ANDROGEN RECEPTOR; PROTEASOME; SORAFENIB; ANDROGEN; ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; ISOPROTEIN; NICOTINAMIDE; PROTEIN BINDING; PROTEIN KINASE INHIBITOR;

EID: 84866889249     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms130911530     Document Type: Article
Times cited : (16)

References (40)
  • 2
    • 84859879413 scopus 로고    scopus 로고
    • The androgen/androgen receptor axis in prostate cancer
    • Bluemn, E.G.; Nelson, P.S. The androgen/androgen receptor axis in prostate cancer. Curr. Opin. Oncol. 2012, 24, 251-257.
    • (2012) Curr. Opin. Oncol , vol.24 , pp. 251-257
    • Bluemn, E.G.1    Nelson, P.S.2
  • 3
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman, B.J.; Feldman, D. The development of androgen-independent prostate cancer. Nat. Rev. Cancer 2001, 1, 34-45.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 4
    • 51049098138 scopus 로고    scopus 로고
    • Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
    • Locke, J.A.; Guns, E.S.; Lubik, A.A.; Adomat, H.H.; Hendy, S.C.; Wood, C.A.; Ettinger, S.L.; Gleave, M.E.; Nelson, C.C. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res. 2008, 68, 6407-6415.
    • (2008) Cancer Res , vol.68 , pp. 6407-6415
    • Locke, J.A.1    Guns, E.S.2    Lubik, A.A.3    Adomat, H.H.4    Hendy, S.C.5    Wood, C.A.6    Ettinger, S.L.7    Gleave, M.E.8    Nelson, C.C.9
  • 5
    • 82255175103 scopus 로고    scopus 로고
    • Androgen receptor and its splice variants in prostate cancer
    • Haile, S.; Sadar, M.D. Androgen receptor and its splice variants in prostate cancer. Cell Mol. Life Sci. 2011, 68, 3971-3981.
    • (2011) Cell Mol. Life Sci , vol.68 , pp. 3971-3981
    • Haile, S.1    Sadar, M.D.2
  • 6
    • 0345256383 scopus 로고    scopus 로고
    • Constitutive activation of the androgen receptor by a point mutation in the hinge region: A new mechanism for androgen-independent growth in prostate cancer
    • Ceraline, J.; Cruchant, M.D.; Erdmann, E.; Erbs, P.; Kurtz, J.E.; Duclos, B.; Jacqmin, D.; Chopin, D.; Bergerat, J.P. Constitutive activation of the androgen receptor by a point mutation in the hinge region: A new mechanism for androgen-independent growth in prostate cancer. Int. J. Cancer 2004, 108, 152-157.
    • (2004) Int. J. Cancer , vol.108 , pp. 152-157
    • Ceraline, J.1    Cruchant, M.D.2    Erdmann, E.3    Erbs, P.4    Kurtz, J.E.5    Duclos, B.6    Jacqmin, D.7    Chopin, D.8    Bergerat, J.P.9
  • 7
    • 35148833549 scopus 로고    scopus 로고
    • Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence
    • Libertini, S.J.; Tepper, C.G.; Rodriguez, V.; Asmuth, D.M.; Kung, H.J.; Mudryj, M. Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence. Cancer Res. 2007, 67, 9001-9005.
    • (2007) Cancer Res , vol.67 , pp. 9001-9005
    • Libertini, S.J.1    Tepper, C.G.2    Rodriguez, V.3    Asmuth, D.M.4    Kung, H.J.5    Mudryj, M.6
  • 8
    • 79955719838 scopus 로고    scopus 로고
    • Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival
    • Hornberg, E.; Ylitalo, E.B.; Crnalic, S.; Antti, H.; Stattin, P.; Widmark, A.; Bergh, A.; Wikstrom, P. Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival. PLoS One 2011, 6, e19059.
    • (2011) PLoS One , vol.6
    • Hornberg, E.1    Ylitalo, E.B.2    Crnalic, S.3    Antti, H.4    Stattin, P.5    Widmark, A.6    Bergh, A.7    Wikstrom, P.8
  • 10
    • 84861691516 scopus 로고    scopus 로고
    • Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells
    • Harada, N.; Inoue, K.; Yamaji, R.; Nakano, Y.; Inui, H. Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells. Cancer Sci. 2012, 103, 1022-1027.
    • (2012) Cancer Sci , vol.103 , pp. 1022-1027
    • Harada, N.1    Inoue, K.2    Yamaji, R.3    Nakano, Y.4    Inui, H.5
  • 11
    • 84861728843 scopus 로고    scopus 로고
    • Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal
    • Chan, S.C.; Li, Y.; Dehm, S.M. Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal. J. Biol. Chem. 2012, 287, 19736-19749.
    • (2012) J. Biol. Chem , vol.287 , pp. 19736-19749
    • Chan, S.C.1    Li, Y.2    Dehm, S.M.3
  • 12
    • 80052827038 scopus 로고    scopus 로고
    • Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants
    • Mostaghel, E.A.; Marck, B.T.; Plymate, S.R.; Vessella, R.L.; Balk, S.; Matsumoto, A.M.; Nelson, P.S.; Montgomery, R.B. Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants. Clin. Cancer Res. 2011, 17, 5913-5925.
    • (2011) Clin. Cancer Res , vol.17 , pp. 5913-5925
    • Mostaghel, E.A.1    Marck, B.T.2    Plymate, S.R.3    Vessella, R.L.4    Balk, S.5    Matsumoto, A.M.6    Nelson, P.S.7    Montgomery, R.B.8
  • 13
    • 84857360697 scopus 로고    scopus 로고
    • Post-translational modification of the androgen receptor
    • Gioeli, D.; Paschal, B.M. Post-translational modification of the androgen receptor. Mol. Cell Endocrinol. 2012, 352, 70-78.
    • (2012) Mol. Cell Endocrinol , vol.352 , pp. 70-78
    • Gioeli, D.1    Paschal, B.M.2
  • 14
    • 34948900221 scopus 로고    scopus 로고
    • Steroid receptor phosphorylation: A key modulator of multiple receptor functions
    • Weigel, N.L.; Moore, N.L. Steroid receptor phosphorylation: A key modulator of multiple receptor functions. Mol. Endocrinol. 2007, 21, 2311-2319.
    • (2007) Mol. Endocrinol , vol.21 , pp. 2311-2319
    • Weigel, N.L.1    Moore, N.L.2
  • 15
    • 84862653140 scopus 로고    scopus 로고
    • Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways
    • Oh, S.J.; Erb, H.H.; Hobisch, A.; Santer, F.R.; Culig, Z. Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways. Endocr. Relat. Cancer 2012, 19, 305-319.
    • (2012) Endocr. Relat. Cancer , vol.19 , pp. 305-319
    • Oh, S.J.1    Erb, H.H.2    Hobisch, A.3    Santer, F.R.4    Culig, Z.5
  • 18
    • 34548089696 scopus 로고    scopus 로고
    • Unexpected paracrine action of prostate cancer cells harboring a new class of androgen receptor mutation-A new paradigm for cooperation among prostate tumor cells
    • Lapouge, G.; Erdmann, E.; Marcias, G.; Jagla, M.; Monge, A.; Kessler, P.; Serra, S.; Lang, H.; Jacqmin, D.; Bergerat, J.P.; et al. Unexpected paracrine action of prostate cancer cells harboring a new class of androgen receptor mutation-A new paradigm for cooperation among prostate tumor cells. Int. J. Cancer 2007, 121, 1238-1244.
    • (2007) Int. J. Cancer , vol.121 , pp. 1238-1244
    • Lapouge, G.1    Erdmann, E.2    Marcias, G.3    Jagla, M.4    Monge, A.5    Kessler, P.6    Serra, S.7    Lang, H.8    Jacqmin, D.9    Bergerat, J.P.10
  • 19
    • 78049280194 scopus 로고    scopus 로고
    • Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
    • Watson, P.A.; Chen, Y.F.; Balbas, M.D.; Wongvipat, J.; Socci, N.D.; Viale, A.; Kim, K.; Sawyers, C.L. Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor. Proc. Natl. Acad. Sci. USA 2010, 107, 16759-16765.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 16759-16765
    • Watson, P.A.1    Chen, Y.F.2    Balbas, M.D.3    Wongvipat, J.4    Socci, N.D.5    Viale, A.6    Kim, K.7    Sawyers, C.L.8
  • 20
    • 33750452673 scopus 로고    scopus 로고
    • Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1
    • Chen, S.; Xu, Y.; Yuan, X.; Bubley, G.J.; Balk, S.P. Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proc. Natl. Acad. Sci. USA 2006, 103, 15969-15974.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 15969-15974
    • Chen, S.1    Xu, Y.2    Yuan, X.3    Bubley, G.J.4    Balk, S.P.5
  • 21
    • 44449168789 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 in androgen-responsive prostate cancer cell lines: Are GSK inhibitors therapeutically useful
    • Rinnab, L.; Schütz, S.V.; Diesch, J.; Schmid, E.; Kufer, R.; Hautmann, R.E.; Spindler, K.D.; Cronauer, M.V. Inhibition of glycogen synthase kinase-3 in androgen-responsive prostate cancer cell lines: Are GSK inhibitors therapeutically useful? Neoplasia 2008, 10, 624-634.
    • (2008) Neoplasia , vol.10 , pp. 624-634
    • Rinnab, L.1    Schütz, S.V.2    Diesch, J.3    Schmid, E.4    Kufer, R.5    Hautmann, R.E.6    Spindler, K.D.7    Cronauer, M.V.8
  • 22
    • 55049115084 scopus 로고    scopus 로고
    • Target gene-specific regulation of androgen receptor activity by p42/p44 mitogen-activated protein kinase
    • Agoulnik, I.U.; Bingman, W.E., III; Nakka, M.; Li, W.; Wang, Q.; Liu, X.S.; Brown, M.; Weigel, N.L. Target gene-specific regulation of androgen receptor activity by p42/p44 mitogen-activated protein kinase. Mol. Endocrinol. 2008, 22, 2420-2432.
    • (2008) Mol. Endocrinol , vol.22 , pp. 2420-2432
    • Agoulnik, I.U.1    Bingman III, W.E.2    Nakka, M.3    Li, W.4    Wang, Q.5    Liu, X.S.6    Brown, M.7    Weigel, N.L.8
  • 23
    • 58249110391 scopus 로고    scopus 로고
    • Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
    • Hu, R.; Dunn, T.A.; Wei, S.; Isharwal, S.; Veltri, R.W.; Humphreys, E.; Han, M.; Partin, A.W.; Vessella, R.L.; Isaacs, W.B. et al. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res. 2009, 69, 16-22.
    • (2009) Cancer Res , vol.69 , pp. 16-22
    • Hu, R.1    Dunn, T.A.2    Wei, S.3    Isharwal, S.4    Veltri, R.W.5    Humphreys, E.6    Han, M.7    Partin, A.W.8    Vessella, R.L.9    Isaacs, W.B.10
  • 24
    • 77951717947 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3beta promotes nuclear export of the androgen receptor through a CRM1-dependent mechanism in prostate cancer cell lines
    • Schütz, S.V.; Cronauer, M.V.; Rinnab, L. Inhibition of glycogen synthase kinase-3beta promotes nuclear export of the androgen receptor through a CRM1-dependent mechanism in prostate cancer cell lines. J. Cell Biochem. 2010, 109, 1192-1200.
    • (2010) J. Cell Biochem , vol.109 , pp. 1192-1200
    • Schütz, S.V.1    Cronauer, M.V.2    Rinnab, L.3
  • 25
    • 80053297590 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3β counteracts ligand-independent activity of the androgen receptor in castration resistant prostate cancer
    • Schütz, S.V.; Schrader, A.J.; Zengerling, F.; Genze, F.; Cronauer, M.V.; Schrader, M. Inhibition of glycogen synthase kinase-3β counteracts ligand-independent activity of the androgen receptor in castration resistant prostate cancer. PLoS One 2011, 6, e25341.
    • (2011) PLoS One , vol.6
    • Schütz, S.V.1    Schrader, A.J.2    Zengerling, F.3    Genze, F.4    Cronauer, M.V.5    Schrader, M.6
  • 26
    • 84859149259 scopus 로고    scopus 로고
    • IkappaB kinases modulate the activity of the androgen receptor in prostate carcinoma cell lines
    • Jain, G.; Voogdt, C.; Tobias, A.; Spindler, K.D.; Moller, P.; Cronauer, M.V.; Marienfeld, R.B. IkappaB kinases modulate the activity of the androgen receptor in prostate carcinoma cell lines. Neoplasia 2012, 14, 178-189.
    • (2012) Neoplasia , vol.14 , pp. 178-189
    • Jain, G.1    Voogdt, C.2    Tobias, A.3    Spindler, K.D.4    Moller, P.5    Cronauer, M.V.6    Marienfeld, R.B.7
  • 27
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 34
    • 36448965291 scopus 로고    scopus 로고
    • A clinical phase II study with sorafenib in patients with progressive hormone-refractory prostate cancer: A study of the CESAR Central European Society for Anticancer Drug Research-EWIV
    • Steinbild, S.; Mross, K.; Frost, A.; Morant, R.; Gillessen, S.; Dittrich, C.; Strumberg, D.; Hochhaus, A.; Hanauske, A.R.; Edler, L. et al. A clinical phase II study with sorafenib in patients with progressive hormone-refractory prostate cancer: A study of the CESAR Central European Society for Anticancer Drug Research-EWIV. Br. J. Cancer 2007, 97, 1480-1485.
    • (2007) Br. J. Cancer , vol.97 , pp. 1480-1485
    • Steinbild, S.1    Mross, K.2    Frost, A.3    Morant, R.4    Gillessen, S.5    Dittrich, C.6    Strumberg, D.7    Hochhaus, A.8    Hanauske, A.R.9    Edler, L.10
  • 37
    • 72549085535 scopus 로고    scopus 로고
    • Safety and efficacy of sorafenib in patients with castrate resistant prostate cancer: A Phase II study
    • Safarinejad, M.R. Safety and efficacy of sorafenib in patients with castrate resistant prostate cancer: A Phase II study. Urol. Oncol. 2008, 28, 21-27.
    • (2008) Urol. Oncol , vol.28 , pp. 21-27
    • Safarinejad, M.R.1
  • 38
    • 77954412751 scopus 로고    scopus 로고
    • The multikinase inhibitor sorafenib induces caspase-dependent apoptosis in PC-3 prostate cancer cells
    • Huang, R.; Chen, X.Q.; Huang, Y.; Chen, N.; Zeng, H. The multikinase inhibitor sorafenib induces caspase-dependent apoptosis in PC-3 prostate cancer cells. Asian J. Androl. 2010, 12, 527-534.
    • (2010) Asian J. Androl , vol.12 , pp. 527-534
    • Huang, R.1    Chen, X.Q.2    Huang, Y.3    Chen, N.4    Zeng, H.5
  • 40
    • 84862680747 scopus 로고    scopus 로고
    • A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer
    • Beardsley, E.K.; Hotte, S.J.; North, S.; Ellard, S.L.; Winquist, E.; Kollmannsberger, C.; Mukherjee, S.D.; Chi, K.N. A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer. Invest. New Drugs 2012, 30, 1652-1659.
    • (2012) Invest. New Drugs , vol.30 , pp. 1652-1659
    • Beardsley, E.K.1    Hotte, S.J.2    North, S.3    Ellard, S.L.4    Winquist, E.5    Kollmannsberger, C.6    Mukherjee, S.D.7    Chi, K.N.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.