-
2
-
-
33947397957
-
Over-diagnosis and overtreatment of early detected prostate cancer
-
Bangma CH, Roemeling S, Schröder FH. Over-diagnosis and overtreatment of early detected prostate cancer. World J Urol 2007;25:3-9.
-
(2007)
World J Urol
, vol.25
, pp. 3-9
-
-
Bangma, C.H.1
Roemeling, S.2
Schröder, F.H.3
-
3
-
-
77954870381
-
Should prostate-specific antigen screening be offered to asymptomatic men?
-
van Vugt HA, Bangma CH, Roobol MJ. Should prostate-specific antigen screening be offered to asymptomatic men? Expert Rev Anticancer Ther 2010;10:1043-1053.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, pp. 1043-1053
-
-
van Vugt, H.A.1
Bangma, C.H.2
Roobol, M.J.3
-
4
-
-
4744337716
-
Docetaxel and estramustine compared with mitox-antrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP, Tangen CM, Hussain MH et al. Docetaxel and estramustine compared with mitox-antrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004;351:1513-1520.
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
-
5
-
-
4744366279
-
TAX 327 Investigators. Docetaxel plus prednisone or mi-toxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, de Wit R, Berry WR et al.; TAX 327 Investigators. Docetaxel plus prednisone or mi-toxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004;351:1502-1512.
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
de Wit, R.2
Berry, W.R.3
-
6
-
-
20944439837
-
Genitourinary Tract Group of the EORTC. Phase III trial of satraplatin, an oral platinum plus predni-sone vs. prednisone alone in patients with hormone-refractory prostate cancer
-
Sternberg CN, Whelan P, Hetherington J et al.; Genitourinary Tract Group of the EORTC. Phase III trial of satraplatin, an oral platinum plus predni-sone vs. prednisone alone in patients with hormone-refractory prostate cancer. Oncology 2005;68:2-9.
-
(2005)
Oncology
, vol.68
, pp. 2-9
-
-
Sternberg, C.N.1
Whelan, P.2
Hetherington, J.3
-
7
-
-
77956556274
-
Do-cetaxel reintroduction in patients with metastatic castration-resistant docetaxel-sensitive prostate cancer: A retrospective multicentre study
-
Eymard JC, Oudard S, Gravis G et al. Do-cetaxel reintroduction in patients with metastatic castration-resistant docetaxel-sensitive prostate cancer: A retrospective multicentre study. BJU Int 2010;106:974-978.
-
(2010)
BJU Int
, vol.106
, pp. 974-978
-
-
Eymard, J.C.1
Oudard, S.2
Gravis, G.3
-
8
-
-
0028896166
-
Camptothecin and taxol: Discovery to clinic-Thirteenth Bruce F. Cain Me-morial Award Lecture
-
Wall ME, Wani MC. Camptothecin and taxol: Discovery to clinic-Thirteenth Bruce F. Cain Me-morial Award Lecture. Cancer Res 1995;55:753-760.
-
(1995)
Cancer Res
, vol.55
, pp. 753-760
-
-
Wall, M.E.1
Wani, M.C.2
-
9
-
-
1442334562
-
Camptothecin and taxol:Historic achievements in natural products re-search
-
Oberlies NH, Kroll DJ. Camptothecin and taxol:Historic achievements in natural products re-search. J Nat Prod 2004;67:129-135.
-
(2004)
J Nat Prod
, vol.67
, pp. 129-135
-
-
Oberlies, N.H.1
Kroll, D.J.2
-
10
-
-
77955530763
-
SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer
-
Ahmed AA, Lu Z, Jennings NB et al. SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer. Cancer Cell 2010;18: 109-121.
-
(2010)
Cancer Cell
, vol.18
, pp. 109-121
-
-
Ahmed, A.A.1
Lu, Z.2
Jennings, N.B.3
-
11
-
-
70350532518
-
Inhibition of the androgen receptor as a novel mechanism of taxol chemotherapy in prostate cancer
-
Gan L, Chen S, Wang Y et al. Inhibition of the androgen receptor as a novel mechanism of taxol chemotherapy in prostate cancer. Cancer Res 2009; 69:8386-8394.
-
(2009)
Cancer Res
, vol.69
, pp. 8386-8394
-
-
Gan, L.1
Chen, S.2
Wang, Y.3
-
12
-
-
77953380806
-
Targeting the androgen receptor by taxol in castration-resistant prostate cancer
-
Jiang J, Huang H. Targeting the androgen receptor by taxol in castration-resistant prostate cancer. Mol Cell Pharmacol 2010;2:1-5.
-
(2010)
Mol Cell Pharmacol
, vol.2
, pp. 1-5
-
-
Jiang, J.1
Huang, H.2
-
13
-
-
85028107326
-
Drug resistance in metastatic castration-resistant prostate cancer
-
Seruga B, Ocana A, Tannock IF. Drug resistance in metastatic castration-resistant prostate cancer. Nat Rev Clin Oncol 2011;8:12-23.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 12-23
-
-
Seruga, B.1
Ocana, A.2
Tannock, I.F.3
-
14
-
-
0032530533
-
Taxol resistance mediated by transfection of the liver-specific sister gene of P-glycoprotein
-
Childs S, Yeh RL, Hui D et al. Taxol resistance mediated by transfection of the liver-specific sister gene of P-glycoprotein. Cancer Res 1998;58:4160-4167.
-
(1998)
Cancer Res
, vol.58
, pp. 4160-4167
-
-
Childs, S.1
Yeh, R.L.2
Hui, D.3
-
15
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent trans-porters
-
Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: Role of ATP-dependent trans-porters. Nat Rev Cancer 2002;2:48-58.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
16
-
-
77957669395
-
In vitro activity of TXD258 in chemotherapeutic resistant tumor cell lines [abstract 1923]
-
Aller AW, Kraus LA, Bissery M-C. In vitro activity of TXD258 in chemotherapeutic resistant tumor cell lines [abstract 1923]. Proc Am Assoc Cancer Res 2000;41:303.
-
(2000)
Proc Am Assoc Cancer Res
, vol.41
, pp. 303
-
-
Aller, A.W.1
Kraus, L.A.2
Bissery, M.-C.3
-
18
-
-
0034671296
-
Phase I dose-finding study of a new taxane, RPR 109881A, ad-ministered as a one-hour intravenous infusion days 1 and 8 to patients with advanced solid tumors
-
Gelmon KA, Latreille J, Tolcher A et al. Phase I dose-finding study of a new taxane, RPR 109881A, ad-ministered as a one-hour intravenous infusion days 1 and 8 to patients with advanced solid tumors. J Clin Oncol 2000;18:4098-4108.
-
(2000)
J Clin Oncol
, vol.18
, pp. 4098-4108
-
-
Gelmon, K.A.1
Latreille, J.2
Tolcher, A.3
-
19
-
-
82355186752
-
-
Presented at the 91st Annual Meeting of the American Association for Cancer Research, San Francisco, CA, April 1-5
-
Vrignaud P, Lejeune P, Chaplin D et al. In vivo efficacy of TXD258, a new taxoid, against hu-man tumor xenografts. Presented at the 91st Annual Meeting of the American Association for Cancer Research, San Francisco, CA, April 1-5, 2000.
-
(2000)
Vivo efficacy of TXD258, a new taxoid, against human tumor xenografts
-
-
Vrignaud, P.1
Lejeune, P.2
Chaplin, D.3
-
20
-
-
0006523687
-
In vivo isolation and characterization of a docetaxel resistant B16 melanoma
-
Bissery MC, Vrignaud P, Riou JF et al. In vivo isolation and characterization of a docetaxel resistant B16 melanoma. Proc Am Assoc Cancer Res 1995;36:316.
-
(1995)
Proc Am Assoc Cancer Res
, vol.36
, pp. 316
-
-
Bissery, M.C.1
Vrignaud, P.2
Riou, J.F.3
-
21
-
-
82355177612
-
-
Presented at the 91st Annual Meeting of the American Association for Cancer Research, San Francisco, CA, April 1-5
-
Dykes DJ, Sarsat JP, Bissery MC. Efficacy evaluation of TXD258, a taxoid compound, against orthotopic and subcutaneous glioblastomas. Presented at the 91st Annual Meeting of the American Association for Cancer Research, San Francisco, CA, April 1-5, 2000.
-
(2000)
Efficacy evaluation of TXD258, a taxoid compound, against orthotopic and subcutaneous glioblastomas
-
-
Dykes, D.J.1
Sarsat, J.P.2
Bissery, M.C.3
-
22
-
-
84862756895
-
-
U.S. prescribing information, Available at, pdf, accessed June 24,2011
-
Jevtana cabazitaxel [U.S. prescribing information]. Available at http://products.sanofi-aventis.us/jevtana/jevtana.pdf, accessed June 24,2011.
-
-
-
Cabazitaxel, J.1
-
23
-
-
59449102526
-
Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors
-
Mita AC, Denis LJ, Rowinsky EK et al. Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors. Clin Cancer Res 2009;15:723-730.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 723-730
-
-
Mita, A.C.1
Denis, L.J.2
Rowinsky, E.K.3
-
24
-
-
0029783171
-
A population pharmacokinetic model for docetaxel (Tax-otere): Model building and validation
-
Bruno R, Vivier N, Vergniol JC et al. A population pharmacokinetic model for docetaxel (Tax-otere): Model building and validation. J Pharmacokinet Biopharm 1996;24:153-172.
-
(1996)
J Pharmacokinet Biopharm
, vol.24
, pp. 153-172
-
-
Bruno, R.1
Vivier, N.2
Vergniol, J.C.3
-
25
-
-
50849088935
-
A multicenter phase II study of XRP6258 adminis-tered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients
-
Pivot X, Koralewski P, Hidalgo JL et al. A multicenter phase II study of XRP6258 adminis-tered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients. Ann Oncol 2008;19:1547-1552.
-
(2008)
Ann Oncol
, vol.19
, pp. 1547-1552
-
-
Pivot, X.1
Koralewski, P.2
Hidalgo, J.L.3
-
26
-
-
77957682309
-
Predni-sone plus cabazitaxel or mitoxantrone for metastatic cas-tration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
de Bono JS, Oudard S, Ozguroglu M et al. Predni-sone plus cabazitaxel or mitoxantrone for metastatic cas-tration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial. Lan-cet 2010;376:1147-1154.
-
(2010)
Lan-cet
, vol.376
, pp. 1147-1154
-
-
de Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
-
27
-
-
50449085844
-
Optimizing treatment for men with advanced prostate cancer: Expert recommendations and the multidisciplinary approach
-
Fitzpatrick JM, Anderson J, Sternberg CN et al. Optimizing treatment for men with advanced prostate cancer: Expert recommendations and the multidisciplinary approach. Crit Rev Oncol Hematol 2008; 68(suppl 1):S9-S22.
-
(2008)
Crit Rev Oncol Hematol
, vol.68
, Issue.SUPPL. 1
-
-
Fitzpatrick, J.M.1
Anderson, J.2
Sternberg, C.N.3
-
28
-
-
56349121553
-
CYP17 in-hibition as a hormonal strategy for prostate cancer
-
Reid AH, Attard G, Barrie E et al. CYP17 in-hibition as a hormonal strategy for prostate cancer. Nat Clin Pract Urol 2008;5:610-620.
-
(2008)
Nat Clin Pract Urol
, vol.5
, pp. 610-620
-
-
Reid, A.H.1
Attard, G.2
Barrie, E.3
-
29
-
-
61749092850
-
CYP17 block-ade by abiraterone: Further evidence for frequent continued hormone-dependence in castration-resis-tant prostate cancer
-
Ang JE, Olmos D, de Bono JS. CYP17 block-ade by abiraterone: Further evidence for frequent continued hormone-dependence in castration-resis-tant prostate cancer. Br J Cancer 2009;100:671-675.
-
(2009)
Br J Cancer
, vol.100
, pp. 671-675
-
-
Ang, J.E.1
Olmos, D.2
de Bono, J.S.3
-
30
-
-
28544432178
-
Selec-tive blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer
-
Attard G, Belldegrun AS, de Bono JS. Selec-tive blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer. BJU Int 2005; 96:1241-1246.
-
(2005)
BJU Int
, vol.96
, pp. 1241-1246
-
-
Attard, G.1
Belldegrun, A.S.2
de Bono, J.S.3
-
31
-
-
79952253824
-
EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant pros-tate cancer
-
Mottet N, Bellmunt J, Bolla M et al. EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant pros-tate cancer. Eur Urol 2011;59:572-583.
-
(2011)
Eur Urol
, vol.59
, pp. 572-583
-
-
Mottet, N.1
Bellmunt, J.2
Bolla, M.3
-
32
-
-
70349395222
-
Anti-androgens and androgen-depleting therapies in prostate can-cer:New agents for an established target
-
Chen Y, Clegg NJ, Scher HI. Anti-androgens and androgen-depleting therapies in prostate can-cer: New agents for an established target. Lancet Oncol 2009;10:981-991.
-
(2009)
Lancet Oncol
, vol.10
, pp. 981-991
-
-
Chen, Y.1
Clegg, N.J.2
Scher, H.I.3
-
33
-
-
70349140015
-
New agents in metastatic prostate cancer
-
Fizazi K, Massard C. New agents in metastatic prostate cancer. Eur J Cancer 2009;45(suppl 1): 379-380.
-
(2009)
Eur J Cancer
, vol.45
, Issue.SUPPL. 1
, pp. 379-380
-
-
Fizazi, K.1
Massard, C.2
-
34
-
-
1842612441
-
Molecu-lar determinants of resistance to antiandrogen ther-apy
-
Chen CD, Welsbie DS, Tran C et al. Molecu-lar determinants of resistance to antiandrogen ther-apy. Nat Med 2004;10:33-39.
-
(2004)
Nat Med
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
-
35
-
-
68049140791
-
Starving the addiction: New opportunities for durable suppression of AR signaling in prostate cancer
-
Knudsen KE, Scher HI. Starving the addic-tion: New opportunities for durable suppression of AR signaling in prostate cancer. Clin Cancer Res 2009;15:4792-4798.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4792-4798
-
-
Knudsen, K.E.1
Scher, H.I.2
-
36
-
-
67449119425
-
Antitumor activity with CYP17 blockade indicates that castra-tion-resistant prostate cancer frequently remains hormone driven
-
Attard G, Reid AH, Olmos D et al. Antitumor activity with CYP17 blockade indicates that castra-tion-resistant prostate cancer frequently remains hormone driven. Cancer Res 2009;69:4937-4940.
-
(2009)
Cancer Res
, vol.69
, pp. 4937-4940
-
-
Attard, G.1
Reid, A.H.2
Olmos, D.3
-
37
-
-
53749091844
-
Prostate cancer: Moving contributor forward by reinventing the wheel. but this
-
Raghavan D, Klein EA. Prostate cancer: Moving forward by reinventing the wheel. but this time it is round. J Clin Oncol 2008;26:4535-4536.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4535-4536
-
-
Raghavan, D.1
Klein, E.A.2
-
38
-
-
11144262723
-
Overview of dehydroepiandrosterone biosynthesis
-
Auchus RJ. Overview of dehydroepiandros-terone biosynthesis. Semin Reprod Med 2004;22: 281-288.
-
(2004)
Semin Reprod Med
, vol.22
, pp. 281-288
-
-
Auchus, R.J.1
-
39
-
-
0028031372
-
Phar-macology of novel steroidal inhibitors of cyto-chrome P450(17) ÷ (17 ÷-hydroxylase/C17-20 lyase)
-
Barrie SE, Potter GA, Goddard PM et al. Phar-macology of novel steroidal inhibitors of cyto-chrome P450(17) ÷ (17 ÷-hydroxylase/C17-20 lyase). J Steroid Biochem Mol Biol 1994;50:267-273.
-
(1994)
J Steroid Biochem Mol Biol
, vol.50
, pp. 267-273
-
-
Barrie, S.E.1
Potter, G.A.2
Goddard, P.M.3
-
40
-
-
0029058770
-
Novel steroidal inhibitors of human cytochrome P45017 ÷ (17 ÷-hydroxylase-C17,20-lyase): Potential agents for the treatment of prostatic cancer
-
Potter GA, Barrie SE, Jarman M et al. Novel steroidal inhibitors of human cytochrome P45017 ÷ (17 ÷-hydroxylase-C17,20-lyase): Potential agents for the treatment of prostatic cancer. J Med Chem 1995;38:2463-2471.
-
(1995)
J Med Chem
, vol.38
, pp. 2463-2471
-
-
Potter, G.A.1
Barrie, S.E.2
Jarman, M.3
-
41
-
-
0028876284
-
Esters of 3-pyridylacetic acid that combine potent inhibition of 17 ÷-hydroxylase/C17,20-lyase (cytochrome P45017 al-pha) with resistance to esterase hydrolysis
-
Rowlands MG, Barrie SE, Chan F et al. Esters of 3-pyridylacetic acid that combine potent inhibition of 17 ÷-hydroxylase/C17,20-lyase (cytochrome P45017 al-pha) with resistance to esterase hydrolysis. J Med Chem 1995;38:4191-4197.
-
(1995)
J Med Chem
, vol.38
, pp. 4191-4197
-
-
Rowlands, M.G.1
Barrie, S.E.2
Chan, F.3
-
42
-
-
3042784503
-
Hor-monal impact of the 17÷-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer
-
O'Donnell A, Judson I, Dowsett M et al. Hor-monal impact of the 17÷-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. Br J Cancer 2004;90:2317-2325.
-
(2004)
Br J Cancer
, vol.90
, pp. 2317-2325
-
-
O'Donnell, A.1
Judson, I.2
Dowsett, M.3
-
43
-
-
53749090666
-
Phase I clinical trial of a selective inhibitor of CYP17, abiraterone ace-tate, confirms that castration-resistant prostate cancer commonly remains hormone driven
-
Attard G, Reid AH, Yap TA et al. Phase I clinical trial of a selective inhibitor of CYP17, abiraterone ace-tate, confirms that castration-resistant prostate cancer commonly remains hormone driven. J Clin Oncol 2008; 26:4563-4571.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4563-4571
-
-
Attard, G.1
Reid, A.H.2
Yap, T.A.3
-
44
-
-
0024237507
-
Androgenic ac-tivity of synthetic progestins and spironolactone in androgen-sensitive mouse mammary carcinoma (Shionogi) cells in culture
-
Luthy IA, Begin DJ, Labrie F. Androgenic ac-tivity of synthetic progestins and spironolactone in androgen-sensitive mouse mammary carcinoma (Shionogi) cells in culture. J Steroid Biochem 1988; 31:845-852.
-
(1988)
J Steroid Biochem
, vol.31
, pp. 845-852
-
-
Luthy, I.A.1
Begin, D.J.2
Labrie, F.3
-
45
-
-
77951523950
-
Phase I clin-ical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with cas-tration-resistant prostate cancer who received prior ketoconazole therapy
-
Ryan CJ, Smith RM, Fong L et al. Phase I clin-ical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with cas-tration-resistant prostate cancer who received prior ketoconazole therapy. J Clin Oncol 2010;28:1481-1488.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1481-1488
-
-
Ryan, C.J.1
Smith, R.M.2
Fong, L.3
-
46
-
-
68949094223
-
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
-
Attard G, Reid AH, A'Hern R et al. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol 2009;27:3742-3748.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3742-3748
-
-
Attard, G.1
Reid, A.H.2
A'Hern, R.3
-
47
-
-
77951591066
-
Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer
-
Danila DC, Morris MJ, de Bono JS et al. Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer. J Clin Oncol 2010;28:1496-1501.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1496-1501
-
-
Danila, D.C.1
Morris, M.J.2
de Bono, J.S.3
-
48
-
-
53049092194
-
Anti-tumor activity of abiraterone acetate (AA), a CYP17 inhibitor of androgen synthesis, in chemo-therapy naïve and docetaxel pre-treated castration resistant prostate cancer (CRPC)
-
de Bono JS, Attard G, Reid AH et al. Anti-tumor activity of abiraterone acetate (AA), a CYP17 inhibitor of androgen synthesis, in chemo-therapy naïve and docetaxel pre-treated castration resistant prostate cancer (CRPC). J Clin Oncol 2008;26(15 suppl):5005.
-
(2008)
J Clin Oncol
, vol.26
, Issue.15 SUPPL.
, pp. 5005
-
-
de Bono, J.S.1
Attard, G.2
Reid, A.H.3
-
49
-
-
77951518711
-
Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate
-
Reid AH, Attard G, Danila DC et al. Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. J Clin Oncol 2010;28:1489-1495.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1489-1495
-
-
Reid, A.H.1
Attard, G.2
Danila, D.C.3
-
50
-
-
70349740108
-
Phase II multicenter study of chemotherapy (chemo)-naïve castration-resistant prostate cancer (CRPC) not exposed to ketoconazole (keto), treated with abiraterone acetate (AA) plus prednisone
-
Ryan C, Efstathiou E, Smith M et al. Phase II multicenter study of chemotherapy (chemo)-naïve castration-resistant prostate cancer (CRPC) not exposed to ketoconazole (keto), treated with abiraterone acetate (AA) plus prednisone. J Clin Oncol 2009;27(15 suppl):5046.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15 SUPPL.
, pp. 5046
-
-
Ryan, C.1
Efstathiou, E.2
Smith, M.3
-
51
-
-
82355177608
-
Candidate predictors of response to abiraterone acetate in castrate-resistant prostate cancer [abstract 187]. Presented at the American Society of Clinical Oncology Genitourinary Cancers Symposium, Orlando, Florida
-
Efstathiou E, Wen S, Molina A et al. Candidate predictors of response to abiraterone acetate in castrate-resistant prostate cancer [abstract 187]. Presented at the American Society of Clinical Oncology Genitourinary Cancers Symposium, Orlando, Florida, February 26-28, 2009.
-
(2009)
February
, pp. 26-28
-
-
Efstathiou, E.1
Wen, S.2
Molina, A.3
-
52
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med 2011;364:1995-2005.
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
de Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
-
53
-
-
58149165081
-
Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer
-
Erratum in: Clin Cancer Res 2009;15:1506
-
de Bono JS, Scher HI, Montgomery RB et al. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin Cancer Res 2008;14:6302-6309. Erratum in: Clin Cancer Res 2009;15:1506.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6302-6309
-
-
de Bono, J.S.1
Scher, H.I.2
Montgomery, R.B.3
-
54
-
-
58949088650
-
Circulating tumour cell (CTC) counts as intermediate end points in castration-resistant prostate cancer (CRPC): A single-centre experience
-
Olmos D, Arkenau HT, Ang JE et al. Circulating tumour cell (CTC) counts as intermediate end points in castration-resistant prostate cancer (CRPC): A single-centre experience. Ann Oncol 2009;20:27-33.
-
(2009)
Ann Oncol
, vol.20
, pp. 27-33
-
-
Olmos, D.1
Arkenau, H.T.2
Ang, J.E.3
-
55
-
-
66149098947
-
Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer
-
Attard G, Swennenhuis JF, Olmos D et al. Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer. Cancer Res 2009;69:2912-2918.
-
(2009)
Cancer Res
, vol.69
, pp. 2912-2918
-
-
Attard, G.1
Swennenhuis, J.F.2
Olmos, D.3
-
56
-
-
38049123346
-
Transatlantic Prostate Group. Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
-
Attard G, Clark J, Ambroisine L et al.; Transatlantic Prostate Group. Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. Oncogene 2008;27:253-263.
-
(2008)
Oncogene
, vol.27
, pp. 253-263
-
-
Attard, G.1
Clark, J.2
Ambroisine, L.3
-
57
-
-
64249128160
-
Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer
-
Jhavar S, Brewer D, Edwards S et al. Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer. BJU Int 2009;103:1256-1269.
-
(2009)
BJU Int
, vol.103
, pp. 1256-1269
-
-
Jhavar, S.1
Brewer, D.2
Edwards, S.3
-
58
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm SM, Schmidt LJ, Heemers HV et al. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res 2008;68:5469-5477.
-
(2008)
Cancer Res
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
-
59
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo Z, Yang X, Sun F et al. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res 2009;69:2305-2313.
-
(2009)
Cancer Res
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
-
60
-
-
34047181147
-
Drug insight: Role of the androgen receptor in the development and progression of prostate cancer
-
Taplin ME. Drug insight: Role of the androgen receptor in the development and progression of prostate cancer. Nat Clin Pract Oncol 2007;4:236-244.
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 236-244
-
-
Taplin, M.E.1
-
61
-
-
79957497548
-
Expanding treatment options for metastatic prostate cancer
-
Antonarakis ES, Eisenberger MA. Expanding treatment options for metastatic prostate cancer. N Engl J Med 2011;364:2055-2058.
-
(2011)
N Engl J Med
, vol.364
, pp. 2055-2058
-
-
Antonarakis, E.S.1
Eisenberger, M.A.2
-
62
-
-
34347244905
-
Bonetargeted radium-223 in symptomatic, hormonerefractory prostate cancer: A randomised, multicentre, placebo-controlled phase II study
-
Nilsson S, Franzén L, Parker C et al. Bonetargeted radium-223 in symptomatic, hormonerefractory prostate cancer: A randomised, multicentre, placebo-controlled phase II study. Lancet Oncol 2007;8:587-594.
-
(2007)
Lancet Oncol
, vol.8
, pp. 587-594
-
-
Nilsson, S.1
Franzén, L.2
Parker, C.3
-
63
-
-
77957957234
-
Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer
-
Chi KN, Hotte SJ, Yu EY et al. Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer. J Clin Oncol 2010;28:4247-4254.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4247-4254
-
-
Chi, K.N.1
Hotte, S.J.2
Yu, E.Y.3
-
65
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010; 363:411-422.
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
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