Differential activation of anthocyanin biosynthesis in Arabidopsis and tobacco over-expressing an R2R3 MYB from Chinese bayberry

Plant Cell, Tissue and Organ Culture

Volumn 113, Issue 3, 2013, Pages 491-499

  Huang, Yu Ji ^a   Song, Song ^a   Allan, Andrew C ^b   Liu, Xiao Fen ^a   Yin, Xue Ren ^a   Xu, Chang Jie ^a   Chen, Kun Song ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED   (New Zealand)

Author keywords

Anthocyanin; Arabidopsis thaliana; bHLH; Chinese bayberry; MrMYB1; Tobacco (Nicotiana tabacum)

Indexed keywords

ARABIDOPSIS THALIANA; BHLH; CHINESE BAYBERRY; MRMYB1; NICOTIANA TABACUM;

BIOCHEMISTRY; BIOSYNTHESIS; GENES; HISTOLOGY; NUCLEIC ACIDS; PLANTS (BOTANY); TISSUE; TOBACCO; TRANSCRIPTION FACTORS;

ANTHOCYANINS;

ARABIDOPSIS; ARABIDOPSIS THALIANA; MORELLA; MORELLA RUBRA; MYRICACEAE; NICOTIANA TABACUM;

EID: 84878185710     PISSN: 01676857     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11240-013-0291-5     Document Type: Article

References (45)

1. Aharoni A, Ric De Vos CH, Wein M, Sun ZK, Greco R, Kroon A, Mol JNM, O'Connell AP (2001) The strawberry FaMYB1 transcription factor suppresses anthocyanin and flavonol accumulation in transgenic tobacco. Plant J 28: 319-332.
2. Allan AC, Hellens RP, Laing WA (2008) MYB transcription factors that colour our fruit. Trends Plant Sci 13: 99-102.
3. Bai Y, Pattanaik S, Patra B, Werkman JR, Xie CH, Yuan L (2011) Flavonoid-related basic helix-loop-helix regulators, NtAn1a and NtAn1b, of tobacco have originated from ancestors and are functionally active. Planta 234: 363-375.
4. Ban Y, Honda C, Hatsuyama Y, Igarashi M, Bessho H, Moriguchi T (2007) Isolation and functional analysis of a MYB transcription factor gene that is a key regulator for the development of red coloration in apple skin. Plant Cell Physiol 48: 958-970.
5. Baudry A, Caboche M, Lepiniec L (2006) TT8 control its own expression in feedback regulation involving TTG1 and homologous MYB and bHLH factors, allowing a strong and cell-specific accumulation of flavonoids in Arabidopsis thaliana. Plant J 46: 768-779.
6. Bogs J, Jaffé FW, Takos AM, Walker AR, Robinson SP (2007) The grapevine transcription factor VvMYBPA1 regulates proanthocyanidin synthesis during fruit development. Plant Physiol 143: 1347-1361.
7. Borevitz JO, Xia Y, Blount J, Dixon RA, Lamb C (2000) Activation tagging identifies a conserved MYB regulator of phenylpropanoid biosynthesis. Plant Cell 12: 2383-2394.
8. Butelli E, Titta L, Giorgio M, Mock HP, Matros A, Peterek S, Schijlen EGWM, Hall RD, Bovy AG, Luo J, Martin C (2008) Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors. Nature Biotechnol 26: 1301-1308.
9. Chabouté M-E, Combettes B, Clément B, Gigot C, Philipps G (1998) Molecular characterization of tobacco ribonucleotide reductase RNR1 and RNR2 cDNAs and cell cycle-regulated expression in synchronized plant cells. Plant Mol Biol 38: 797-806.
10. Clough SJ, Bent AF (1998) Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J 16: 735-743.
11. Cutanda-Perez M-C, Ageorges A, Gomez C, Vialet S, Terrier N, Romieu C, Torregrosa L (2009) Ectopic expression of VlmybA1 in grapevine activates a narrow set of genes involved in anthocyanin synthesis and transport. Plant Mol Biol 69: 633-648.
12. Deluc L, Bogs J, Walker AR, Ferrier T, Decendit A, Merillon JM, Robinson RP, Barrieu F (2008) The transcription factor VvMYB5b contributes to the regulation of anthocyanin and proanthocyanidin biosynthesis in developing grape berries. Plant Physiol 147: 2041-2053.
13. Espley RV, Hellens RP, Putterill J, Stevenson DE, Kutty-Amma S, Allan AC (2007) Red colouration in apple fruit is due to the activity of the MYB transcription factor, MdMYB10. Plant J 49: 414-427.
14. Espley RV, Bovy A, Bava C, Jaeger SR, Tomes S, Norling C, Crawford J, Rowan D, McGhie TK, Brendolise C, Putterill J, Schouten HJ, Hellens RP, Allan AC (2012) Analysis of genetically modified red-fleshed apples reveals effects on growth and consumer attributes. Plant Biotechnol J. doi: 10. 1111/pbi. 12017.
15. Feller A, Machemer K, Braun EL, Grotewold E (2011) Evolutionary and comparative analysis of MYB and bHLH plant transcription factors. Plant J 66: 94-116.
16. Feng SQ, Wang YL, Yang S, Xu YT, Chen XS (2010) Anthocyanin biosynthesis in pears is regulated by a R2R3-MYB transcription factor PyMYB10. Planta 232: 245-255.
17. Feng C, Chen M, Xu CJ, Bai L, Yin XR, Li X, Allan AC, Ferguson IB, Chen KS (2012) Transcriptomic analysis of Chinese bayberry (Myrica rubra) fruit development and ripening using RNA-Seq. BMC Genomics 13: 19.
18. Gao JJ, Shen XF, Zhang Z, Peng RH, Xiong AS, Xu J, Zhu B, Zheng JL, Yao QH (2011) The myb transcription factor MdMYB6 suppresses anthocyanin biosynthesis in transgenic Arabidopsis. Plant Cell Tiss Organ Cult 106: 235-242.
19. Grotewold E (2006) The genetics and biochemistry of floral pigments. Annu Rev Plant Biol 57: 761-780.
20. Hellens RP, Allan AC, Friel EN, Bolitho K, Grafton K, Templeton MD, Karunairetnam S, Gleave AP, Laing WA (2005) Transient expression vectors for functional genomics, quantification of promoter activity and RNA silencing in plants. Plant Methods 1: 13.
21. Hichri I, Barrieu F, Bogs J, Kappel C, Delrot S, Lauvergeat V (2011) Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway. J Exp Bot 62: 2465-2483.
22. Holton T, Cornish E (1995) Genetics and biochemistry of anthocyanin biosynthesis. Plant Cell 7: 1071-1083.
23. Horsch RB, Fry JE, Hoffmann NL, Eichholtz D, Rogers SG, Fraley RT (1985) A simple and general method for transferring genes into plants. Science 227: 1229-1231.
24. Huang YJ, Yin XR, Zhu CQ, Wang WW, Grierson D, Xu CJ, Chen KS (2013) Standard addition quantitative real-time PCR (SAQPCR): a novel approach for determination of transgene copy number avoiding pcr efficiency estimation. PLOS ONE 8: e53489.
25. Jin H, Martin C (1999) Multifunctionality and diversity within the plant MYB-gene family. Plant Mol Biol 41: 577-585.
26. Laitinen RAE, Ainasoja M, Broholm SK, Teeri TH, Elomaa P (2008) Identification of target genes for a MYB-type anthocyanin regulator in Gerbera hybrida. J Exp Bot 59: 3691-3703.
27. Lin-Wang K, Bolitho K, Grafton K, Kortstee A, Karunairetnam S, McGhie TK, Espley RV, Hellens RP, Allan AC (2010) An R2R3 MYB transcription factor associated with regulation of the anthocyanin biosynthetic pathway in Rosaceae. BMC Plant Biol 10: 50.
28. Lloyd AM, Walbot V, Davis RW (1992) Arabidopsis and Nicotiana anthocyanin production activated by maize regulators R and C1. Science 258: 1773-1775.
29. Mathews H, Clendennen SK, Caldwell CG, Liu XL, Connors K, Matheis N, Schuster DK, Menasco DJ, Wagoner W, Lightner J, Wagner D (2003) Activation tagging in tomato identifies a transcriptional regulator of anthocyanin biosynthesis, modification, and transport. Plant Cell 15: 1689-1703.
30. Mooney M, Desnos T, Harrison K, Jones J, Carpenter R, Coen E (1995) Altered regulation of tomato and tobacco pigmentation genes caused by the delila gene of Antirrhinum. Plant J 7: 333-339.
31. Niu SS, Xu CJ, Zhang WS, Zhang B, Li X, Lin-Wang K, Ferguson IB, Allan AC, Chen KS (2010) Coordinated regulation of anthocyanin biosynthesis in Chinese bayberry (Myrica rubra) fruit by a R2R3 MYB transcription factor. Planta 231: 887-899.
32. Park JS, Kim JB, Cho KJ, Cheon CI, Sung MK, Choung MG, Roh KH (2008) Arabidopsis R2R3-MYB transcription factor AtMYB60 functions as a transcriptional repressor of anthocyanin biosynthesis in lettuce (Lactuca sativa). Plant Cell Rep 27: 985-994.
33. Pattanaik S, Kong Q, Zaitlin D, Werkman JR, Xie CH, Patra B, Yuan L (2010) Isolation and functional characterization of a floral tissue-specific R2R3 MYB regulator from tobacco. Planta 231: 1061-1076.
34. Paz-Ares J, Ghosal D, Wienand U, Peterson PA, Saedler H (1987) The regulatory c1 locus of Zea mays encodes a protein with homology to myb proto-oncogene products and with structural similarities to transcriptional activators. EMBO J 6: 3553-3558.
35. Quattrocchio F, Wing JF, van der Woude K, Mol J, Koes R (1998) Analysis of bHLH and MYB domain proteins: species-specific regulatory differences are caused by divergent evolution of target anthocyanin genes. Plant J 13: 475-488.
36. Quattrocchio F, Verweij W, Kroon A, Spelt C, Mol J, Koes R (2006) PH4 of petunia is an R2R3 MYB protein that activates vacuolar acidification through interactions with Basic-Helix-Loop-Helix transcription factors of the anthocyanin pathway. Plant Cell 18: 1274-1291.
37. Schwinn K, Venail J, Shang Y, Mackay S, Alm V, Butelli E, Oyama R, Bailey P, Davies K, Martin C (2006) A small family of MYB-regulatory genes controls floral pigmentation intensity and patterning in the genus Antirrhinum. Plant Cell 18: 831-851.
38. Shan LL, Li X, Wang P, Cai C, Zhang B, Sun CD, Zhang WS, Xu CJ, Ferguson IB, Chen KS (2008) Characterization of cDNAs associated with lignification and their expression profiles in loquat fruit with different lignin accumulation. Planta 227: 1243-1254.
39. Spelt C, Quattrocchio F, Mol JN, Koes R (2000) Anthocyanin1of petunia encodes a basic helix-loop-helix protein that directly activates transcription of structural anthocyanin genes. Plant Cell 12: 1619-1632.
40. Sun CD, Zheng YX, Tang XL, Jiang M, Zhang JK, Li X, Chen KS (2012a) Purification and anti-tumor activity of cyanidin-3-O-glucoside from Chinese bayberry fruit. Food Chem 13: 1287-1294.
41. Sun CD, Zhang B, Zhang JK, Xu CJ, Wu YL, Li X, Chen KS (2012b) Cyanidin-3-glucoside-rich extract from Chinese bayberry fruit protects pancreatic β cells and ameliorates hyperglycemia in streptozotocin-induced diabetic mice. J Med Food 15: 288-298.
42. Walker AR, Davison PA, Bolognesi-Winfield AC, James CM, Srinivasan N, Blundell TL, Esch JJ, Marks MD, Gray JC (1999) The Transparent Testa Glabra1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein. Plant Cell 11: 1337-1350.
43. Wang WW, Zhu CQ, Liu XH, Chen KS, Xu CJ (2011) Techniques for rapid preparation of tomato leaf DNA and its application in real-time quantitative PCR-based transgene detection. Hereditas (Beijing) 33: 1017-1022.
44. Yoshida K, Kume N, Nakaya Y, Yamagami A, Nakano T, Sakuta M (2010) Comparative analysis of the triplicate proanthocyanidin regulators in Lotus japonicus. Plant Cell Physiol 51: 912-922.
45. Zhang WS, Li X, Zheng JT, Wang GY, Sun CD, Ferguson IB, Chen KS (2008) Bioactive components and antioxidant capacity of Chinese bayberry (Myrica rubra Sieb. and Zucc.) fruit in relation to fruit maturity and postharvest storage. Eur Food Res Technol 227: 1091-1097.