CD4+ T cells, but not CD8+ T cells, are required for the development of experimental autoimmune gastritis

Immunology

Volumn 93, Issue 3, 1998, Pages 405-408

  De Silva, H D ^a   Van Driel, I R ^a   La Gruta, N ^a   Toh, B H ^a   Gleeson, P A ^a  

^a MONASH UNIVERSITY MEDICAL SCHOOL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; GASTRITIS; HELPER CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPATHOGENESIS; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; THYMECTOMY;

ANIMALS; ANTIBODIES, MONOCLONAL; AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; GASTRITIS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED BALB C; THYMECTOMY;

EID: 0031889835     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1998.00436.x     Document Type: Article

References (19)

1. KOJIMA A. & PREHN R. (1981) Genetic susceptibility to post thymectomy autoimmune disease in mice. Immunogenetics 14, 15.
2. FUKUMA K., SAKAGUCHI S., KURIBAYASHI K. et al. (1988) Immunologic and clinical studies on murine experimental autoimmune gastritis induced by neonatal thymectomy. Gastroenterology 94, 274.
3. TUNG K.S., SMITH S., FEUSCHER C. GOLDSTEIN G., COOK C. & ANDERSON R.E. (1987) Murine autoimmune oophoritis. epididymoorchitis and gastritis induced by day-3 thymectomy. Immunopathology. Am J Pathol 126, 293.
4. TOH B.H., GLEESON P.A., SIMPSON R.J. et al. (1990) The 60- to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a β-subunit of the gastric H/K-ATPase (proton pump). Proc Natl Acad Sci USA 87, 6418.
5. JONES C.M., CALLAGHAN J.M., GLEESON P.A., MORI Y., MASUDA T. & TOH B.H. (1991) The parietal cell autoantigens recognized in neonatal thymectomy-induced murine gastritis are the alpha and beta subunits of the gastric proton pump [published erratum appears in Gastroenterology 1992 102(5), 1829]. Gastroenterology 101, 287.
6. KONTANI K., TAGUCHI O. & TAKAHASHI T. (1992) Involvement of the H +/K +-ATPase alpha-subunit as a major antigenic protein in autoimmune gastritis induced by neonatal thymectomy in mice. Clin Exp Immunol 89, 63.
7. GLEESON P.A. & TOH B.H. (1991) Molecular targets in pernicious anaemia. Immunol Today 12, 233.
8. MARTINELLI T., GLEESON P.A., VAN DRIEL I. & TOH B.H. (1996) Analysis of mononuclear cell infiltrate associated with murine experimental autoimmune gastritis. Gastroenterology 110, 1791.
9. SAKAGUCHI S., FUKUMA K., KURIBAYASHI K. & MASUDA T. (1985) Organ-specific autoimmune diseases induced in mice by elimination of T cell subsets. J Exp Med 161, 72.
10. SMITH H., LOU Y.H., LACY P. & TUNG K.S.K. (1992) Tolerance mechanism in experimental ovarian and gastric autoimmune diseases. J Immunol 149, 2212.
11. ALDERUCCIO F., TOH B.H., TAN S.S., GLEESON P.A. & VAN DRIEL I.R. (1993) An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus. J Exp Med 178, 419.
12. DIALYNAS D.P., QUAN Z.S., WALL K.A. et al. (1983) Characterisation of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK 1-5: similarity of L3T4 to the human Leu-3T4 molecule. J Immunol 131, 2445.
13. COBBOLD S.P., JAYASURIYA A., NASH A., PROSPERO T.D. & WALDMANN H. (1984) Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo. Nature 312, 548.
14. GODING J.W. (1986) Monoclonal Antibodies: Principles and Practice, p. 98. Academic Press, Sydney.
15. + Tcell fusion partner. J Exp Med 170, 1887.
16. BARRETT S.P., TOH B.H., ALDERUCCIO F., VAN DRIEL I.R. & GLEESON P.A. (1995a) Organ-specific autoimmunity induced by adult thymectomy and cyclophosphamide-induced lymphopenia. Eur J Immunol 25, 238.
17. CALLAGHAN J.M., TOH B.-H., SIMPSON R., BALDWIN G.B. & GLEESON P.A. (1992) Purification of the gastric proton pump complex ( H +/K + ATPase) by tomato-lectin Sepharose 4B chromatography. Biochem J 283, 63.
18. + T cells in the initiation of insulin-dependent diabetes mellitus. Eur J Immunol 26, 1762.
19. + T cells are essential to induce experimental autoimmune myasthenia gravis. J Exp Med 184, 349.