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Volumn 9, Issue 2, 2013, Pages 155-162

The Clinical and Forensic Toxicology of Z-drugs

Author keywords

Analysis; Poisoning; Zaleplon; Zolpidem; Zopiclone

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANTIFUNGAL AGENT; BENZODIAZEPINE; CARBAMAZEPINE; CENTRAL DEPRESSANT AGENT; CHLORPROMAZINE; CIMETIDINE; CIPROFLOXACIN; ERYTHROMYCIN; ESZOPICLONE; FLUMAZENIL; FLUVOXAMINE; HYPERICUM PERFORATUM EXTRACT; PROTEINASE INHIBITOR; RIFAMPICIN; THIORIDAZINE; ZALEPLON; ZOLPIDEM; ZOPICLONE;

EID: 84878109850     PISSN: 15569039     EISSN: 19376995     Source Type: Journal    
DOI: 10.1007/s13181-013-0292-0     Document Type: Article
Times cited : (143)

References (82)
  • 1
    • 0037272830 scopus 로고    scopus 로고
    • Zopiclone and zaleplon vs benzodiazepines in the treatment of insomnia: Canadian consensus statement
    • Montplaisir J, Hawa R, Moller H et al (2003) Zopiclone and zaleplon vs benzodiazepines in the treatment of insomnia: Canadian consensus statement. Hum Psychopharmacol 18(1): 29-38.
    • (2003) Hum Psychopharmacol , vol.18 , Issue.1 , pp. 29-38
    • Montplaisir, J.1    Hawa, R.2    Moller, H.3
  • 2
    • 33751117992 scopus 로고    scopus 로고
    • Insomnia comorbidity and impact and hypnotic use by age group in a national survey population aged 16 to 74 years
    • Stewart R, Besset A, Bebbington P et al (2006) Insomnia comorbidity and impact and hypnotic use by age group in a national survey population aged 16 to 74 years. Sleep 29(11): 1391-1397.
    • (2006) Sleep , vol.29 , Issue.11 , pp. 1391-1397
    • Stewart, R.1    Besset, A.2    Bebbington, P.3
  • 3
    • 28044462641 scopus 로고    scopus 로고
    • Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits
    • Glass J, Lanctot KL, Herrmann N et al (2005) Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits. BMJ 331(7526): 1169.
    • (2005) Bmj , vol.331 , Issue.7526 , pp. 1169
    • Glass, J.1    Lanctot, K.L.2    Herrmann, N.3
  • 4
    • 34247849449 scopus 로고    scopus 로고
    • Use of non-benzodiazepine hypnotics in the elderly: are all agents the same?
    • Dolder C, Nelson M, McKinsey J (2007) Use of non-benzodiazepine hypnotics in the elderly: are all agents the same? CNS Drugs 21(5): 389-405.
    • (2007) CNS Drugs , vol.21 , Issue.5 , pp. 389-405
    • Dolder, C.1    Nelson, M.2    McKinsey, J.3
  • 5
    • 80053210607 scopus 로고    scopus 로고
    • Role of zolpidem in the management of insomnia
    • Dang A, Garg A, Rataboli PV (2011) Role of zolpidem in the management of insomnia. CNS Neurosci Ther 17(5): 387-397.
    • (2011) CNS Neurosci Ther , vol.17 , Issue.5 , pp. 387-397
    • Dang, A.1    Garg, A.2    Rataboli, P.V.3
  • 6
    • 0034489167 scopus 로고    scopus 로고
    • Non-benzodiazepines for the treatment of insomnia
    • Wagner J, Wagner ML (2000) Non-benzodiazepines for the treatment of insomnia. Sleep Med Rev 4(6): 551-581.
    • (2000) Sleep Med Rev , vol.4 , Issue.6 , pp. 551-581
    • Wagner, J.1    Wagner, M.L.2
  • 7
    • 55949132650 scopus 로고    scopus 로고
    • Hypnosedative-induced complex behaviours: incidence, mechanisms and management
    • Dolder CR, Nelson MH (2008) Hypnosedative-induced complex behaviours: incidence, mechanisms and management. CNS Drugs 22(12): 1021-1036.
    • (2008) CNS Drugs , vol.22 , Issue.12 , pp. 1021-1036
    • Dolder, C.R.1    Nelson, M.H.2
  • 8
    • 17444420295 scopus 로고    scopus 로고
    • Benefit-risk assessment of zaleplon in the treatment of insomnia
    • Barbera J, Shapiro C (2005) Benefit-risk assessment of zaleplon in the treatment of insomnia. Drug Saf 28(4): 301-318.
    • (2005) Drug Saf , vol.28 , Issue.4 , pp. 301-318
    • Barbera, J.1    Shapiro, C.2
  • 9
    • 3042660145 scopus 로고    scopus 로고
    • Residual effects of sleep medication on driving ability
    • Verster JC, Veldhuijzen DS, Volkerts ER (2004) Residual effects of sleep medication on driving ability. Sleep Med Rev 8(4): 309-325.
    • (2004) Sleep Med Rev , vol.8 , Issue.4 , pp. 309-325
    • Verster, J.C.1    Veldhuijzen, D.S.2    Volkerts, E.R.3
  • 10
    • 77955154079 scopus 로고    scopus 로고
    • A receptor modulators as hypnotics
    • A receptor modulators as hypnotics. J Psychopharmacol 24(11): 1601-1612.
    • (2010) J Psychopharmacol , vol.24 , Issue.11 , pp. 1601-1612
    • Nutt, D.J.1    Stahl, S.M.2
  • 12
    • 34249064580 scopus 로고    scopus 로고
    • Zolpidem extended-release: a single insomnia treatment option for sleep induction and sleep maintenance symptoms
    • Barkin RL (2007) Zolpidem extended-release: a single insomnia treatment option for sleep induction and sleep maintenance symptoms. Am J Ther 14(3): 299-305.
    • (2007) Am J Ther , vol.14 , Issue.3 , pp. 299-305
    • Barkin, R.L.1
  • 13
    • 0034011740 scopus 로고    scopus 로고
    • Zolpidem: an update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia
    • Holm KJ, Goa KL (2000) Zolpidem: an update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia. Drugs 59(4): 865-889.
    • (2000) Drugs , vol.59 , Issue.4 , pp. 865-889
    • Holm, K.J.1    Goa, K.L.2
  • 14
    • 77955166113 scopus 로고    scopus 로고
    • What one hand giveth the other taketh away: some unpredicted effects of enantiomers in psychopharmacology
    • Nutt DJ, Feetam CL (2010) What one hand giveth the other taketh away: some unpredicted effects of enantiomers in psychopharmacology. J Psychopharmacol 24(8): 1137-1141.
    • (2010) J Psychopharmacol , vol.24 , Issue.8 , pp. 1137-1141
    • Nutt, D.J.1    Feetam, C.L.2
  • 15
    • 0035841617 scopus 로고    scopus 로고
    • Pyrazolopyrimidines
    • George CF (2001) Pyrazolopyrimidines. Lancet 358(9293): 1623-1626.
    • (2001) Lancet , vol.358 , Issue.9293 , pp. 1623-1626
    • George, C.F.1
  • 16
    • 1842609539 scopus 로고    scopus 로고
    • Comparative pharmacokinetics and pharmacodynamics of short-acting hypnosedatives: zaleplon, zolpidem and zopiclone
    • Drover DR (2004) Comparative pharmacokinetics and pharmacodynamics of short-acting hypnosedatives: zaleplon, zolpidem and zopiclone. Clin Pharmacokinet 43(4): 227-238.
    • (2004) Clin Pharmacokinet , vol.43 , Issue.4 , pp. 227-238
    • Drover, D.R.1
  • 17
    • 33750720598 scopus 로고    scopus 로고
    • Dynamics and kinetics of a modified-release formulation of zolpidem: comparison with immediate-release standard zolpidem and placebo
    • Greenblatt DJ, Legangneux E, Harmatz JS et al (2006) Dynamics and kinetics of a modified-release formulation of zolpidem: comparison with immediate-release standard zolpidem and placebo. J Clin Pharmacol 46(12): 1469-1480.
    • (2006) J Clin Pharmacol , vol.46 , Issue.12 , pp. 1469-1480
    • Greenblatt, D.J.1    Legangneux, E.2    Harmatz, J.S.3
  • 19
    • 33745233068 scopus 로고    scopus 로고
    • Eszopiclone, a nonbenzodiazepine sedative-hypnotic agent for the treatment of transient and chronic insomnia
    • Najib J (2006) Eszopiclone, a nonbenzodiazepine sedative-hypnotic agent for the treatment of transient and chronic insomnia. Clin Ther 28(4): 491-516.
    • (2006) Clin Ther , vol.28 , Issue.4 , pp. 491-516
    • Najib, J.1
  • 20
    • 67349208203 scopus 로고    scopus 로고
    • Sublingual zolpidem is more effective than oral zolpidem in initiating early onset of sleep in the post-nap model of transient insomnia: a polysomnographic study
    • Staner L, Eriksson M, Cornette F et al (2009) Sublingual zolpidem is more effective than oral zolpidem in initiating early onset of sleep in the post-nap model of transient insomnia: a polysomnographic study. Sleep Med 10(6): 616-620.
    • (2009) Sleep Med , vol.10 , Issue.6 , pp. 616-620
    • Staner, L.1    Eriksson, M.2    Cornette, F.3
  • 22
    • 77955150195 scopus 로고    scopus 로고
    • Pharmacokinetics of (S)-zopiclone and (S)-desmethylzopiclone following dosing with zopiclone and eszopiclone
    • Brunello N, Bettica P, Amato D et al (2008) Pharmacokinetics of (S)-zopiclone and (S)-desmethylzopiclone following dosing with zopiclone and eszopiclone. Eur Neuropsychopharmacol 18(S4): S581-S582.
    • (2008) Eur Neuropsychopharmacol , vol.18 , Issue.S4
    • Brunello, N.1    Bettica, P.2    Amato, D.3
  • 23
    • 0027440229 scopus 로고
    • Pharmacokinetics of zopiclone and its enantiomers in Caucasian young healthy volunteers
    • Fernandez C, Maradeix V, Gimenez F et al (1993) Pharmacokinetics of zopiclone and its enantiomers in Caucasian young healthy volunteers. Drug Metab Dispos 21(6): 1125-1128.
    • (1993) Drug Metab Dispos , vol.21 , Issue.6 , pp. 1125-1128
    • Fernandez, C.1    Maradeix, V.2    Gimenez, F.3
  • 25
    • 55949116700 scopus 로고    scopus 로고
    • Utility of flumazenil in zopiclone overdose
    • Yang C-C, Deng J-F (2008) Utility of flumazenil in zopiclone overdose. Clin Toxicol (Phila) 46(9): 920-921.
    • (2008) Clin Toxicol (Phila) , vol.46 , Issue.9 , pp. 920-921
    • Yang, C.-C.1    Deng, J.-F.2
  • 26
    • 0028117531 scopus 로고
    • Flumazenil antagonizes the central effects of zolpidem, an imidazopyridine hypnotic
    • Patat A, Naef MM, van Gessel E et al (1994) Flumazenil antagonizes the central effects of zolpidem, an imidazopyridine hypnotic. Clin Pharmacol Ther 56(4): 430-436.
    • (1994) Clin Pharmacol Ther , vol.56 , Issue.4 , pp. 430-436
    • Patat, A.1    Naef, M.M.2    van Gessel, E.3
  • 27
    • 0036354629 scopus 로고    scopus 로고
    • Zaleplon-induced coma and bluish-green urine: possible antidotal effect by flumazenil
    • Hojer J, Salmonson H, Sundin P (2002) Zaleplon-induced coma and bluish-green urine: possible antidotal effect by flumazenil. J Toxicol Clin Toxicol 40(5): 571-572.
    • (2002) J Toxicol Clin Toxicol , vol.40 , Issue.5 , pp. 571-572
    • Hojer, J.1    Salmonson, H.2    Sundin, P.3
  • 28
    • 0036786419 scopus 로고    scopus 로고
    • Zolpidem pharmacokinetic properties in young females: influence of smoking and oral contraceptive use
    • Olubodun JO, Ochs HR, Truten V et al (2002) Zolpidem pharmacokinetic properties in young females: influence of smoking and oral contraceptive use. J Clin Pharmacol 42(10): 1142-1146.
    • (2002) J Clin Pharmacol , vol.42 , Issue.10 , pp. 1142-1146
    • Olubodun, J.O.1    Ochs, H.R.2    Truten, V.3
  • 29
    • 83555176128 scopus 로고    scopus 로고
    • Potentially harmful drug-drug interactions in the elderly: a review
    • Hines LE, Murphy JE (2011) Potentially harmful drug-drug interactions in the elderly: a review. Am J Geriatr Pharmacother 9(6): 364-377.
    • (2011) Am J Geriatr Pharmacother , vol.9 , Issue.6 , pp. 364-377
    • Hines, L.E.1    Murphy, J.E.2
  • 30
    • 0038281508 scopus 로고    scopus 로고
    • Clinically important drug interactions with zopiclone, zolpidem and zaleplon
    • Hesse LM, von Moltke LL, Greenblatt DJ (2003) Clinically important drug interactions with zopiclone, zolpidem and zaleplon. CNS Drugs 17(7): 513-532.
    • (2003) CNS Drugs , vol.17 , Issue.7 , pp. 513-532
    • Hesse, L.M.1    von Moltke, L.L.2    Greenblatt, D.J.3
  • 31
    • 80055061104 scopus 로고    scopus 로고
    • Drug interaction between St John's wort and zolpidem in healthy subjects
    • Hojo Y, Echizenya M, Ohkubo T et al (2011) Drug interaction between St John's wort and zolpidem in healthy subjects. J Clin Pharm Ther 36(6): 711-715.
    • (2011) J Clin Pharm Ther , vol.36 , Issue.6 , pp. 711-715
    • Hojo, Y.1    Echizenya, M.2    Ohkubo, T.3
  • 32
    • 12944331138 scopus 로고    scopus 로고
    • Zolpidem: a review of its use in the management of insomnia
    • Swainston Harrison T, Keating GM (2005) Zolpidem: a review of its use in the management of insomnia. CNS Drugs 19(1): 65-89.
    • (2005) CNS Drugs , vol.19 , Issue.1 , pp. 65-89
    • Swainston Harrison, T.1    Keating, G.M.2
  • 33
    • 79960714888 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between zolpidem and carbamazepine in healthy volunteers
    • Vlase L, Popa A, Neag M et al (2011) Pharmacokinetic interaction between zolpidem and carbamazepine in healthy volunteers. J Clin Pharmacol 51(8): 1233-1236.
    • (2011) J Clin Pharmacol , vol.51 , Issue.8 , pp. 1233-1236
    • Vlase, L.1    Popa, A.2    Neag, M.3
  • 34
    • 79953804041 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between zolpidem and ciprofloxacin in healthy volunteers
    • Vlase L, Popa A, Neag M et al (2011) Pharmacokinetic interaction between zolpidem and ciprofloxacin in healthy volunteers. Eur J Drug Metab Pharmacokinet 35(3-4): 83-87.
    • (2011) Eur J Drug Metab Pharmacokinet , vol.35 , Issue.3-4 , pp. 83-87
    • Vlase, L.1    Popa, A.2    Neag, M.3
  • 35
    • 34447323452 scopus 로고    scopus 로고
    • US Food & Drug Administration htm Accessed 1 Dec 2012
    • US Food & Drug Administration (2007) FDA Requests Label Change for All Sleep Disorder Drug Products. http://www. fda. gov/NewsEvents/Newsroom/PressAnnouncements/2007/ucm108868. htm Accessed 1 Dec 2012.
    • (2007) FDA Requests Label Change for All Sleep Disorder Drug Products
  • 36
    • 37249027172 scopus 로고    scopus 로고
    • New-onset transient hallucinations possibly due to eszopiclone: a case study
    • Duggal HS (2007) New-onset transient hallucinations possibly due to eszopiclone: a case study. Prim Care Companion J Clin Psychiatry 9(6): 468-469.
    • (2007) Prim Care Companion J Clin Psychiatry , vol.9 , Issue.6 , pp. 468-469
    • Duggal, H.S.1
  • 37
    • 41149147052 scopus 로고    scopus 로고
    • Dose-related illusions and hallucinations with zaleplon
    • Stone JR, Zorick TS, Tsuang J (2008) Dose-related illusions and hallucinations with zaleplon. Clin Toxicol (Phila) 46(4): 344-345.
    • (2008) Clin Toxicol (Phila) , vol.46 , Issue.4 , pp. 344-345
    • Stone, J.R.1    Zorick, T.S.2    Tsuang, J.3
  • 38
    • 0344271024 scopus 로고    scopus 로고
    • A novel clinical pattern of visual hallucination after zolpidem use
    • Tsai MJ, Huang YB, Wu PC (2003) A novel clinical pattern of visual hallucination after zolpidem use. J Toxicol Clin Toxicol 41(6): 869-872.
    • (2003) J Toxicol Clin Toxicol , vol.41 , Issue.6 , pp. 869-872
    • Tsai, M.J.1    Huang, Y.B.2    Wu, P.C.3
  • 39
    • 0031868743 scopus 로고    scopus 로고
    • Zolpidem-associated hallucinations and serotonin reuptake inhibition: a possible interaction
    • Elko CJ, Burgess JL, Robertson WO (1998) Zolpidem-associated hallucinations and serotonin reuptake inhibition: a possible interaction. J Toxicol Clin Toxicol 36(3): 195-203.
    • (1998) J Toxicol Clin Toxicol , vol.36 , Issue.3 , pp. 195-203
    • Elko, C.J.1    Burgess, J.L.2    Robertson, W.O.3
  • 40
    • 2442541272 scopus 로고    scopus 로고
    • The pharmacology and mechanisms of action of new generation, non-benzodiazepine hypnotic agents
    • Sanger DJ (2004) The pharmacology and mechanisms of action of new generation, non-benzodiazepine hypnotic agents. CNS Drugs 18(S1): 9-15.
    • (2004) CNS Drugs , vol.18 , Issue.S1 , pp. 9-15
    • Sanger, D.J.1
  • 41
    • 0142029653 scopus 로고    scopus 로고
    • Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data
    • Hajak G, Muller WE, Wittchen HU et al (2003) Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data. Addiction 98(10): 1371-1378.
    • (2003) Addiction , vol.98 , Issue.10 , pp. 1371-1378
    • Hajak, G.1    Muller, W.E.2    Wittchen, H.U.3
  • 42
    • 79960519026 scopus 로고    scopus 로고
    • Zolpidem withdrawal delirium, seizure, and acute psychosis: case reports and literature review
    • Chien C-C, Huanga H-T, Lung F-W et al (2011) Zolpidem withdrawal delirium, seizure, and acute psychosis: case reports and literature review. J Subs Use 16(4): 330-338.
    • (2011) J Subs Use , vol.16 , Issue.4 , pp. 330-338
    • Chien, C.-C.1    Huanga, H.-T.2    Lung, F.-W.3
  • 44
    • 34447294279 scopus 로고    scopus 로고
    • Evidence of zolpidem abuse and dependence: results of the French Centre for Evaluation and Information on Pharmacodependence (CEIP) network survey
    • Victorri-Vigneau C, Dailly E, Veyrac G et al (2007) Evidence of zolpidem abuse and dependence: results of the French Centre for Evaluation and Information on Pharmacodependence (CEIP) network survey. Br J Clin Pharmacol 64(2): 198-209.
    • (2007) Br J Clin Pharmacol , vol.64 , Issue.2 , pp. 198-209
    • Victorri-Vigneau, C.1    Dailly, E.2    Veyrac, G.3
  • 45
    • 38849085098 scopus 로고    scopus 로고
    • Zopiclone: is it a pharmacologic agent for abuse?
    • Cimolai N (2007) Zopiclone: is it a pharmacologic agent for abuse? Can Fam Physician 53(12): 2124-2129.
    • (2007) Can Fam Physician , vol.53 , Issue.12 , pp. 2124-2129
    • Cimolai, N.1
  • 46
    • 84856919378 scopus 로고    scopus 로고
    • Methods for the analysis of nonbenzodiazepine hypnotic drugs in biological matrices
    • Tonon MA, Bonato PS (2012) Methods for the analysis of nonbenzodiazepine hypnotic drugs in biological matrices. Bioanalysis 4(3): 291-304.
    • (2012) Bioanalysis , vol.4 , Issue.3 , pp. 291-304
    • Tonon, M.A.1    Bonato, P.S.2
  • 47
    • 0029916857 scopus 로고    scopus 로고
    • Two cases of fatal zopiclone overdose
    • Boniface PJ, Russell SG (1996) Two cases of fatal zopiclone overdose. J Anal Toxicol 20(2): 131-133.
    • (1996) J Anal Toxicol , vol.20 , Issue.2 , pp. 131-133
    • Boniface, P.J.1    Russell, S.G.2
  • 48
    • 84862782217 scopus 로고    scopus 로고
    • Evaluation of postmortem redistribution phenomena for commonly encountered drugs
    • Han E, Kim E, Hong H et al (2012) Evaluation of postmortem redistribution phenomena for commonly encountered drugs. Forensic Sci Int 219(1-3): 265-271.
    • (2012) Forensic Sci Int , vol.219 , Issue.1-3 , pp. 265-271
    • Han, E.1    Kim, E.2    Hong, H.3
  • 49
    • 24144434966 scopus 로고    scopus 로고
    • Screening and confirmatory method for benzodiazepines and hypnotics in oral fluid by LC-MS/MS
    • Kintz P, Villain M, Concheiro M et al (2005) Screening and confirmatory method for benzodiazepines and hypnotics in oral fluid by LC-MS/MS. Forensic Sci Int 150(2-3): 213-220.
    • (2005) Forensic Sci Int , vol.150 , Issue.2-3 , pp. 213-220
    • Kintz, P.1    Villain, M.2    Concheiro, M.3
  • 50
    • 0037287627 scopus 로고    scopus 로고
    • Post-mortem toxicology: what the dead can and cannot tell us
    • Leikin JB, Watson WA (2003) Post-mortem toxicology: what the dead can and cannot tell us. J Toxicol Clin Toxicol 41(1): 47-56.
    • (2003) J Toxicol Clin Toxicol , vol.41 , Issue.1 , pp. 47-56
    • Leikin, J.B.1    Watson, W.A.2
  • 52
    • 84856425446 scopus 로고    scopus 로고
    • Detection and validated quantification of 21 benzodiazepines and 3 "z-drugs" in human hair by LC-MS/MS
    • Rust KY, Baumgartner MR, Meggiolaro N et al (2012) Detection and validated quantification of 21 benzodiazepines and 3 "z-drugs" in human hair by LC-MS/MS. Forensic Sci Int 215(1-3): 64-72.
    • (2012) Forensic Sci Int , vol.215 , Issue.1-3 , pp. 64-72
    • Rust, K.Y.1    Baumgartner, M.R.2    Meggiolaro, N.3
  • 53
    • 0034534720 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacodynamics, and relative pharmacokinetic/pharmacodynamic profiles of zaleplon and zolpidem
    • Drover D, Lemmens H, Naidu S et al (2000) Pharmacokinetics, pharmacodynamics, and relative pharmacokinetic/pharmacodynamic profiles of zaleplon and zolpidem. Clin Ther 22(12): 1443-1461.
    • (2000) Clin Ther , vol.22 , Issue.12 , pp. 1443-1461
    • Drover, D.1    Lemmens, H.2    Naidu, S.3
  • 54
    • 22944487628 scopus 로고    scopus 로고
    • Toxicological findings in cases of alleged drug-facilitated sexual assault in the United Kingdom over a 3-year period
    • Scott-Ham M, Burton FC (2005) Toxicological findings in cases of alleged drug-facilitated sexual assault in the United Kingdom over a 3-year period. J Clin Forensic Med 12(4): 175-186.
    • (2005) J Clin Forensic Med , vol.12 , Issue.4 , pp. 175-186
    • Scott-Ham, M.1    Burton, F.C.2
  • 55
    • 0035182658 scopus 로고    scopus 로고
    • Fatal overdose of zopiclone in an elderly woman with bronchogenic carcinoma
    • Bramness JG, Arnestad M, Karinen R et al (2001) Fatal overdose of zopiclone in an elderly woman with bronchogenic carcinoma. J Forensic Sci 46(5): 1247-1249.
    • (2001) J Forensic Sci , vol.46 , Issue.5 , pp. 1247-1249
    • Bramness, J.G.1    Arnestad, M.2    Karinen, R.3
  • 56
    • 0027941454 scopus 로고
    • Acute zolpidem poisoning-analysis of 344 cases
    • Garnier R, Guerault E, Muzard D et al (1994) Acute zolpidem poisoning-analysis of 344 cases. J Toxicol Clin Toxicol 32(4): 391-404.
    • (1994) J Toxicol Clin Toxicol , vol.32 , Issue.4 , pp. 391-404
    • Garnier, R.1    Guerault, E.2    Muzard, D.3
  • 57
    • 80052339991 scopus 로고    scopus 로고
    • Toxicological investigations of drivers killed in road traffic accidents in Norway during 2006-2008
    • Gjerde H, Christophersen AS, Normann PT et al (2011) Toxicological investigations of drivers killed in road traffic accidents in Norway during 2006-2008. Forensic Sci Int 212(1-3): 102-109.
    • (2011) Forensic Sci Int , vol.212 , Issue.1-3 , pp. 102-109
    • Gjerde, H.1    Christophersen, A.S.2    Normann, P.T.3
  • 58
    • 0032827129 scopus 로고    scopus 로고
    • Acute zolpidem overdose-report of two cases
    • Gock SB, Wong SH, Nuwayhid N et al (1999) Acute zolpidem overdose-report of two cases. J Anal Toxicol 23(6): 559-562.
    • (1999) J Anal Toxicol , vol.23 , Issue.6 , pp. 559-562
    • Gock, S.B.1    Wong, S.H.2    Nuwayhid, N.3
  • 59
    • 84865659672 scopus 로고    scopus 로고
    • Concentrations of zolpidem and zopiclone in venous blood samples from impaired drivers compared with femoral blood from forensic autopsies
    • Jones AW, Holmgren A (2012) Concentrations of zolpidem and zopiclone in venous blood samples from impaired drivers compared with femoral blood from forensic autopsies. Forensic Sci Int 222(1-3): 118-123.
    • (2012) Forensic Sci Int , vol.222 , Issue.1-3 , pp. 118-123
    • Jones, A.W.1    Holmgren, A.2
  • 60
    • 84878106026 scopus 로고    scopus 로고
    • Sanofi-Aventis Accessed 1 Dec 2012
    • Sanofi-Aventis (2011) Product monograph: Imovane (zopiclone). http://products. sanofi. ca/en/imovane. pdf Accessed 1 Dec 2012.
    • (2011) Product monograph: Imovane (zopiclone)
  • 61
    • 57049132743 scopus 로고    scopus 로고
    • Distribution of zolpidem in body fluids and organ tissues in five autopsy cases
    • Takayasu T, Ishida Y, Kimura A et al (2008) Distribution of zolpidem in body fluids and organ tissues in five autopsy cases. Forensic Toxicol 26(2): 80-84.
    • (2008) Forensic Toxicol , vol.26 , Issue.2 , pp. 80-84
    • Takayasu, T.1    Ishida, Y.2    Kimura, A.3
  • 63
    • 70449701839 scopus 로고    scopus 로고
    • Oral fluid testing for drugs of abuse
    • Bosker WM, Huestis MA (2009) Oral fluid testing for drugs of abuse. Clin Chem 55(11): 1910-1931.
    • (2009) Clin Chem , vol.55 , Issue.11 , pp. 1910-1931
    • Bosker, W.M.1    Huestis, M.A.2
  • 64
    • 29144494822 scopus 로고    scopus 로고
    • Validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of 26 benzodiazepines and metabolites, zolpidem and zopiclone, in blood, urine, and hair
    • Laloup M, Ramirez Fernandez Mdel M, De Boeck G et al (2005) Validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of 26 benzodiazepines and metabolites, zolpidem and zopiclone, in blood, urine, and hair. J Anal Toxicol 29(7): 616-626.
    • (2005) J Anal Toxicol , vol.29 , Issue.7 , pp. 616-626
    • Laloup, M.1    Ramirez Fernandez Mdel, M.2    De Boeck, G.3
  • 65
    • 84860247084 scopus 로고    scopus 로고
    • Value of the concept of minimal detectable dosage in human hair
    • Kintz P (2012) Value of the concept of minimal detectable dosage in human hair. Forensic Sci Int 218(1-3): 28-30.
    • (2012) Forensic Sci Int , vol.218 , Issue.1-3 , pp. 28-30
    • Kintz, P.1
  • 66
    • 70350493486 scopus 로고    scopus 로고
    • Zaleplon (Sonata) analysis in postmortem specimens by gas chromatography-electron capture detection
    • Anderson DT, Budd RD (2009) Zaleplon (Sonata) analysis in postmortem specimens by gas chromatography-electron capture detection. J Anal Toxicol 33(8): 481-485.
    • (2009) J Anal Toxicol , vol.33 , Issue.8 , pp. 481-485
    • Anderson, D.T.1    Budd, R.D.2
  • 67
    • 0033025222 scopus 로고    scopus 로고
    • Zolpidem distribution in postmortem cases
    • Levine B, Wu SC, Smialek JE (1999) Zolpidem distribution in postmortem cases. J Forensic Sci 44(2): 369-371.
    • (1999) J Forensic Sci , vol.44 , Issue.2 , pp. 369-371
    • Levine, B.1    Wu, S.C.2    Smialek, J.E.3
  • 68
    • 0028358394 scopus 로고
    • Zopiclone poisoning: tissue distribution and potential for postmortem diffusion
    • Pounder DJ, Davies JI (1994) Zopiclone poisoning: tissue distribution and potential for postmortem diffusion. Forensic Sci Int 65(3): 177-183.
    • (1994) Forensic Sci Int , vol.65 , Issue.3 , pp. 177-183
    • Pounder, D.J.1    Davies, J.I.2
  • 69
    • 79960554734 scopus 로고    scopus 로고
    • Zolpidem misuse with other medications or alcohol frequently results in intensive care unit admission
    • Zosel A, Osterberg EC, Mycyk MB (2011) Zolpidem misuse with other medications or alcohol frequently results in intensive care unit admission. Am J Ther 18(4): 305-308.
    • (2011) Am J Ther , vol.18 , Issue.4 , pp. 305-308
    • Zosel, A.1    Osterberg, E.C.2    Mycyk, M.B.3
  • 71
    • 77957776203 scopus 로고    scopus 로고
    • Coma with absent brainstem reflexes resulting from zolpidem overdose
    • Kuzniar TJ, Balagani R, Radigan KA et al (2010) Coma with absent brainstem reflexes resulting from zolpidem overdose. Am J Ther 17(5): e172-e174.
    • (2010) Am J Ther , vol.17 , Issue.5
    • Kuzniar, T.J.1    Balagani, R.2    Radigan, K.A.3
  • 72
    • 0034907389 scopus 로고    scopus 로고
    • Acute zolpidem overdose leading to coma and respiratory failure
    • Hamad A, Sharma N (2001) Acute zolpidem overdose leading to coma and respiratory failure. Intensive Care Med 27(7): 1239.
    • (2001) Intensive Care Med , vol.27 , Issue.7 , pp. 1239
    • Hamad, A.1    Sharma, N.2
  • 73
    • 34250885058 scopus 로고    scopus 로고
    • Prolonged coma after eszopiclone overdose
    • Lovett B, Watts D, Grossman M (2007) Prolonged coma after eszopiclone overdose. Am J Emerg Med 25(6): 735, e735-736.
    • (2007) Am J Emerg Med , vol.25 , Issue.6 , pp. 735-736
    • Lovett, B.1    Watts, D.2    Grossman, M.3
  • 74
    • 38949207166 scopus 로고    scopus 로고
    • Two cases of methemoglobinemia following zopiclone ingestion
    • Fung HT, Lai CH, Wong OF et al (2008) Two cases of methemoglobinemia following zopiclone ingestion. Clin Toxicol (Phila) 46(2): 167-170.
    • (2008) Clin Toxicol (Phila) , vol.46 , Issue.2 , pp. 167-170
    • Fung, H.T.1    Lai, C.H.2    Wong, O.F.3
  • 75
    • 70350450381 scopus 로고    scopus 로고
    • Hemolytic anemia after zopiclone overdose
    • Fung HT, Lai CH, Wong OF et al (2009) Hemolytic anemia after zopiclone overdose. Clin Toxicol (Phila) 47(9): 902-903.
    • (2009) Clin Toxicol (Phila) , vol.47 , Issue.9 , pp. 902-903
    • Fung, H.T.1    Lai, C.H.2    Wong, O.F.3
  • 76
    • 57449087275 scopus 로고    scopus 로고
    • Zopiclone-associated methemoglobinemia and renal impairment
    • Kung SW, Tse ML, Chan YC et al (2008) Zopiclone-associated methemoglobinemia and renal impairment. Clin Toxicol (Phila) 46(10): 1099-1100.
    • (2008) Clin Toxicol (Phila) , vol.46 , Issue.10 , pp. 1099-1100
    • Kung, S.W.1    Tse, M.L.2    Chan, Y.C.3
  • 78
    • 0030050706 scopus 로고    scopus 로고
    • Flumazenil dans les intoxications au Zolpidem chez l'enfant
    • Carbajal R, Blanc P, Paupe A et al (1996) Flumazenil dans les intoxications au Zolpidem chez l'enfant. Arch Ped 3(2): 191-192.
    • (1996) Arch Ped , vol.3 , Issue.2 , pp. 191-192
    • Carbajal, R.1    Blanc, P.2    Paupe, A.3
  • 79
    • 84865863429 scopus 로고    scopus 로고
    • Toxicology and characteristics of deaths involving zolpidem in New South Wales, Australia 2001-2010
    • Darke S, Deady M, Duflou J (2012) Toxicology and characteristics of deaths involving zolpidem in New South Wales, Australia 2001-2010. J Forensic Sci 57(5): 1259-1262.
    • (2012) J Forensic Sci , vol.57 , Issue.5 , pp. 1259-1262
    • Darke, S.1    Deady, M.2    Duflou, J.3
  • 80
    • 0442323138 scopus 로고    scopus 로고
    • Changes in fatalities due to overdose of anxiolytic and sedative drugs in the UK (1983-1999)
    • Buckley NA, McManus PR (2004) Changes in fatalities due to overdose of anxiolytic and sedative drugs in the UK (1983-1999). Drug Saf 27(2): 135-141.
    • (2004) Drug Saf , vol.27 , Issue.2 , pp. 135-141
    • Buckley, N.A.1    McManus, P.R.2
  • 81
    • 0346734259 scopus 로고    scopus 로고
    • Comparison of the fatal toxicity index of zopiclone with benzodiazepines
    • Reith DM, Fountain J, McDowell R et al (2003) Comparison of the fatal toxicity index of zopiclone with benzodiazepines. J Toxicol Clin Toxicol 41(7): 975-980.
    • (2003) J Toxicol Clin Toxicol , vol.41 , Issue.7 , pp. 975-980
    • Reith, D.M.1    Fountain, J.2    McDowell, R.3
  • 82
    • 0037678664 scopus 로고    scopus 로고
    • Mixed drug intoxication involving zaleplon ("Sonata")
    • Moore KA, Zemrus TL, Ramcharitar V et al (2003) Mixed drug intoxication involving zaleplon ("Sonata"). Forensic Sci Int 134(2-3): 120-122.
    • (2003) Forensic Sci Int , vol.134 , Issue.2-3 , pp. 120-122
    • Moore, K.A.1    Zemrus, T.L.2    Ramcharitar, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.