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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 12, 2013, Pages 3500-3504

Design, synthesis and structure activity relationships of spirocyclic compounds as potent CCR1 antagonists

(5) Hossain, Nafizal a Ivanova, Svetlana a Bergare, Jonas a Mensonides Harsema, Marguérite a Cooper, Martin E a

a ASTRAZENECA R AND D (Sweden)

Author keywords

Antagonists; CCR1; Chemokines hERG; Spirocyclic

Indexed keywords

CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR1 ANTAGONIST; ORGANIC COMPOUND; SPIROCYCLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; HUMANS; RECEPTORS, CCR1; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84878106101 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.04.047 Document Type: Article

Times cited : (5)

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