Identification of novel series of human CCR1 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 6, 2008, Pages 2215-2221

  Xie, Yun Feng ^a   Sircar, Ila ^a   Lake, Kirk ^a   Komandla, Mallareddy ^a   Ligsay, Kathleen ^a   Li, Jian ^a   Xu, Kui ^a   Parise, Jason ^a   Schneider, Lisa ^a   Huang, Dingqiu ^a   Liu, Juping ^a   Sakurai, Naoki ^a   Barbosa, Miguel ^a   Jack, Rick ^a  

^a Tanabe Research Laboratories   (United States)

Author keywords

CCR1 antagonist; Chemokine receptor 1

Indexed keywords

CALCIUM; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5;

ARTICLE; CALCIUM TRANSPORT; CHEMOTAXIS; DRUG CONFORMATION; DRUG DETERMINATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HIGH THROUGHPUT SCREENING; HYDROGEN BOND; IC 50; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

CALCIUM; CELL LINE; CELL MOVEMENT; CHEMOKINE CCL3; CHEMOTAXIS; HUMANS; MOLECULAR STRUCTURE; MONOCYTES; PIPERIDINES; RECEPTORS, CCR1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 40749128432     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.09.068     Document Type: Article

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