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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 6, 2013, Pages 1883-1886

Spirocyclic compounds, potent CCR1 antagonists

(4) Hossain, Nafizal a Ivanova, Svetlana a Bergare, Jonas a Eriksson, Tomas a

a ASTRAZENECA R AND D (Sweden)

Author keywords

Antagonists; Chemokines; Chemotaxis; Spirocycles

Indexed keywords

CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR1 ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; DRUG DETERMINATION; DRUG PENETRATION; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN; RAT;

ANIMALS; CACO-2 CELLS; CELL LINE; CHEMOTAXIS; HUMANS; MICROSOMES, LIVER; PIPERIDINES; PROTEIN BINDING; RATS; RECEPTORS, CCR1; SPIRO COMPOUNDS;

EID: 84874655840 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.12.095 Document Type: Article

Times cited : (8)

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