Effect of genetic polymorphisms of OPRM1, ABCB1, CYP3A4/5 on postoperative fentanyl consumption in Korean gynecological patients

International Journal of Clinical Pharmacology and Therapeutics

Volumn 51, Issue 5, 2013, Pages 383-392

  Kim, Kye Min ^a   Kim, Ho Sook ^b,c   Lim, Se Hun ^a   Cheong, Soon Ho ^a   Choi, Eun Jung ^b   Kang, Hyun ^d   Choi, Hey Ran ^a   Jeon, Jin Woo ^a   Yon, Jun Heum ^a   Oh, Minkyung ^b   Shin, Jae Gook ^b,c  

^a Inje University College of Medicine   (South Korea)

^b Inje University College of Medicine   (South Korea)

^c Department of Clinical Pharmacology ^*  (South Korea)

^d Chung Ang University   (South Korea)

Author keywords

Analgesia; Fentanyl; Pharmacogenetics; Postoperative pain

Indexed keywords

CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; FENTANYL; MU OPIATE RECEPTOR; MULTIDRUG RESISTANCE PROTEIN 1; ABCB1 PROTEIN, HUMAN; CYP3A4 PROTEIN, HUMAN; CYP3A5 PROTEIN, HUMAN; CYTOCHROME P450 3A; MULTIDRUG RESISTANCE PROTEIN; NARCOTIC ANALGESIC AGENT; OPRM1 PROTEIN, HUMAN;

ABDOMINAL HYSTERECTOMY; ADULT; AGED; ARTICLE; ATP BINDING CASSETTE B1 GENE; CONTROLLED STUDY; CYP3A4 GENE; CYP3A5 GENE; DISEASE SEVERITY; FEMALE; GENE; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC VARIABILITY; HUMAN; LAPAROSCOPY; MAJOR CLINICAL STUDY; MOTION SICKNESS; OPRM1 GENE; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; SINGLE NUCLEOTIDE POLYMORPHISM; VAGINAL HYSTERECTOMY; VISUAL ANALOG SCALE; ASIAN; CHI SQUARE DISTRIBUTION; CLINICAL TRIAL; ETHNOLOGY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GYNECOLOGIC SURGERY; METABOLISM; MIDDLE AGED; PHENOTYPE; POSTOPERATIVE CARE; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SOUTH KOREA; STATISTICAL MODEL;

ADULT; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; ASIAN CONTINENTAL ANCESTRY GROUP; CHI-SQUARE DISTRIBUTION; CYTOCHROME P-450 CYP3A; FEMALE; FENTANYL; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; HYSTERECTOMY, VAGINAL; LAPAROSCOPY; LINEAR MODELS; LOGISTIC MODELS; MIDDLE AGED; P-GLYCOPROTEIN; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PHENOTYPE; POLYMORPHISM, GENETIC; POSTOPERATIVE CARE; RECEPTORS, OPIOID, MU; REPUBLIC OF KOREA; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

MLCS; MLOWN;

EID: 84878105387     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: 10.5414/CP201824     Document Type: Article

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