CD4+ T cells producing interleukin (IL)-17, IL-22 and interferon-γ are major effector T cells in nickel allergy

Contact Dermatitis

Volumn 68, Issue 6, 2013, Pages 339-347

  Dyring Andersen, Beatrice ^a,b   Skov, Lone ^b   Løvendorf, Marianne B ^b   Bzorek, Michael ^c   Søndergaard, Knud ^c   Lauritsen, Jens Peter H ^a   Dabelsteen, Sally ^a   Geisler, Carsten ^a   Menné Bonefeld, Charlotte ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^c NAESTVED HOSPITAL   (Denmark)

Author keywords

T cells; allergic contact dermatitis; CD4+ T cells; CD8+ T cells; IFN ; IL 17; IL 22; nickel allergy

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 22;

ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FLOW CYTOMETRY; GAMMA DELTA T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; NICKEL HYPERSENSITIVITY; T LYMPHOCYTE SUBPOPULATION;

BIOLOGICAL MARKERS; BIOPSY; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DERMATITIS, ALLERGIC CONTACT; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKINS; LYMPHOCYTE COUNT; NICKEL; SKIN; T-LYMPHOCYTE SUBSETS;

EID: 84878095248     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/cod.12043     Document Type: Article

References (43)

1. Gocinski B L, Tigelaar R E., Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion J Immunol 1990: 144: 4121-4128.
2. He D, Wu L, Kim H K, Li H, Elmets C A, Xu H., CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses J Immunol 2006: 177: 6852-6858.
3. Pennino D, Eyerich K, Scarponi C et al., IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes J Immunol 2010: 184: 4880-4888.
4. Cavani A, Nasorri F, Ottaviani C, Sebastiani S, De P O, Girolomoni G., Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals J Immunol 2003: 171: 5760-5768.
5. Bangert C, Friedl J, Stary G, Stingl G, Kopp T., Immunopathologic features of allergic contact dermatitis in humans: participation of plasmacytoid dendritic cells in the pathogenesis of the disease? J Invest Dermatol 2003: 121: 1409-1418.
6. Xu H, DiIulio N A, Fairchild R L., T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells J Exp Med 1996: 183: 1001-1012.
7. Jakobson E, Masjedi K, Ahlborg N, Lundeberg L, Karlberg A T, Scheynius A., Cytokine production in nickel-sensitized individuals analysed with enzyme-linked immunospot assay: possible implication for diagnosis Br J Dermatol 2002: 147: 442-449.
8. Larsen J M, Bonefeld C M, Poulsen S S, Geisler C, Skov L., IL-23 and T(H)17-mediated inflammation in human allergic contact dermatitis J Allergy Clin Immunol 2009: 123: 486-492.
9. Ricciardi L, Minciullo P L, Saitta S, Trombetta D, Saija A, Gangemi S., Increased serum levels of IL-22 in patients with nickel contact dermatitis Contact Dermatitis 2009: 60: 57-58.
10. O'Connor W Jr, Zenewicz L A, Flavell R A., The dual nature of T(H)17 cells: shifting the focus to function Nat Immunol 2010: 11: 471-476.
11. Rubin I M, Dabelsteen S, Nielsen M M, White I R, Johansen J D, Geisler C, Bonefeld C M., Repeated exposure to hair dye induces regulatory T cells in mice Br J Dermatol 2010: 163: 992-998.
12. Nakae S, Komiyama Y, Nambu A et al., Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses Immunity 2002: 17: 375-387.
13. Albanesi C, Scarponi C, Cavani A, Federici M, Nasorri F, Girolomoni G., Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes J Invest Dermatol 2000: 115: 81-87.
14. Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F., Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells Nat Immunol 2009: 10: 857-863.
15. Res P C, Piskin G, de Boer O J, van der Loos C M, Teeling P, Bos J D, Teunissen M B., Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis PLoS ONE 2010: 5: e14108.
16. Ness-Schwickerath K J, Morita C T., Regulation and function of IL-17A- and IL-22-producing gammadelta T cells Cell Mol Life Sci 2011: 68: 2371-2390.
17. Moreira-Teixeira L, Resende M, Coffre M et al., Proinflammatory environment dictates the IL-17-producing capacity of human invariant NKT cells J Immunol 2011: 186: 5758-5765.
18. Girardi M, Oppenheim D E, Steele C R et al., Regulation of cutaneous malignancy by gammadelta T cells Science 2001: 294: 605-609.
19. Jameson J, Ugarte K, Chen N, Yachi P, Fuchs E, Boismenu R, Havran W L., A role for skin gammadelta T cells in wound repair Science 2002: 296: 747-749.
20. Girardi M., Immunosurveillance and immunoregulation by gammadelta T cells J Invest Dermatol 2006: 126: 25-31.
21. Havran W L, Jameson J M., Epidermal T cells and wound healing J Immunol 2010: 184: 5423-5428.
22. Laggner U, Di M P, Perera G K et al., Identification of a novel proinflammatory human skin-homing Vgamma9Vdelta2 T cell subset with a potential role in psoriasis J Immunol 2011: 187: 2783-2793.
23. Huber H, Descossy P, van Brandwijk R, Knop J., Activation of murine epidermal TCR-gamma delta+ T cells by keratinocytes treated with contact sensitizers J Immunol 1995: 155: 2888-2894.
24. Ptak W, Askenase P W., Gamma delta T cells assist alpha beta T cells in adoptive transfer of contact sensitivity J Immunol 1992: 149: 3503-3508.
25. Dieli F, Ptak W, Sireci G, Romano G C, Potestio M, Salerno A, Asherson G L., Cross-talk between V beta 8+ and gamma delta+ T lymphocytes in contact sensitivity Immunology 1998: 93: 469-477.
26. Dieli F, Asherson G L, Sireci G, Dominici R, Gervasi F, Vendetti S, Colizzi V, Salerno A., Gamma delta cells involved in contact sensitivity preferentially rearrange the Vgamma3 region and require interleukin-7 Eur J Immunol 1997: 27: 206-214.
27. Wilkinson D S, Fregert S, Magnusson B et al., Terminology of contact dermatitis Acta Derm Venereol 1970: 50: 287-292.
28. Roden A C, Morice W G, Hanson C A., Immunophenotypic attributes of benign peripheral blood gammadelta T cells and conditions associated with their increase Arch Pathol Lab Med 2008: 132: 1774-1780.
29. Martins E B, Graham A K, Chapman R W, Fleming K A., Elevation of gamma delta T lymphocytes in peripheral blood and livers of patients with primary sclerosing cholangitis and other autoimmune liver diseases Hepatology 1996: 23: 988-993.
30. Komori H K, Witherden D A, Kelly R, Sendaydiego K, Jameson J M, Teyton L, Havran W L., Cutting edge: dendritic epidermal gammadelta T cell ligands are rapidly and locally expressed by keratinocytes following cutaneous wounding J Immunol 2012: 188: 2972-2976.
31. Sutton C E, Lalor S J, Sweeney C M, Brereton C F, Lavelle E C, Mills K H., Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity Immunity 2009: 31: 331-341.
32. Werfel T, Hentschel M, Renz H, Kapp A., Analysis of the phenotype and cytokine pattern of blood- and skin-derived nickel specific T cells in allergic contact dermatitis Int Arch Allergy Immunol 1997: 113: 384-386.
33. Zhao Y, Balato A, Fishelevich R, Chapoval A, Mann D L, Gaspari A A., Th17/Tc17 infiltration and associated cytokine gene expression in elicitation phase of allergic contact dermatitis Br J Dermatol 2009: 161: 1301-1306.
34. Nordlind K, Liden S., Gamma/delta T cells and human skin reactivity to heavy metals Arch Dermatol Res 1995: 287: 137-141.
35. Groh V, Porcelli S, Fabbi M et al., Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system J Exp Med 1989: 169: 1277-1294.
36. Holtmeier W, Pfander M, Hennemann A, Zollner T M, Kaufmann R, Caspary W F., The TCR-delta repertoire in normal human skin is restricted and distinct from the TCR-delta repertoire in the peripheral blood J Invest Dermatol 2001: 116: 275-280.
37. Sullivan S, Bergstresser P R, Tigelaar R E, Streilein J W., Induction and regulation of contact hypersensitivity by resident, bone marrow-derived, dendritic epidermal cells: Langerhans cells and Thy-1+ epidermal cells J Immunol 1986: 137: 2460-2467.
38. Welsh E A, Kripke M L., Murine Thy-1+ dendritic epidermal cells induce immunologic tolerance in vivo J Immunol 1990: 144: 883-891.
39. Caccamo N, Battistini L, Bonneville M et al., CXCR5 identifies a subset of Vgamma9Vdelta2 T cells which secrete IL-4 and IL-10 and help B cells for antibody production J Immunol 2006: 177: 5290-5295.
40. Cai Y, Shen X, Ding C et al., Pivotal role of dermal IL-17-producing gammadelta T cells in skin inflammation Immunity 2011: 35: 596-610.
41. Boniface K, Guignouard E, Pedretti N et al., A role for T cell-derived interleukin 22 in psoriatic skin inflammation Clin Exp Immunol 2007: 150: 407-415.
42. Watanabe H, Gaide O, Petrilli V et al., Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity J Invest Dermatol 2007: 127: 1956-1963.
43. Cho K A, Suh J W, Lee K H, Kang J L, Woo S Y., IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1beta by keratinocytes via the ROS-NLRP3-caspase-1 pathway Int Immunol 2012: 24: 147-158.