Elevation of γδ T lymphocytes in peripheral blood and livers of patients with primary sclerosing cholangitis and other autoimmune liver diseases

Hepatology

Volumn 23, Issue 5, 1996, Pages 988-993

  Martins, Eduardo B G ^a   Graham, Andrew K ^a   Chapman, Roger W ^a   Fleming, Kenneth A ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ADULT; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNE HEPATITIS; AUTOIMMUNITY; CHRONIC LIVER DISEASE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPATHOGENESIS; LIVER BIOPSY; LYMPHOCYTOSIS; MAJOR CLINICAL STUDY; MALE; PRIMARY BILIARY CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0029979464     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v23.pm0008621180     Document Type: Article

References (24)

1. Brenner M, McLean J, Dialynas D, Strominger J, Smith J, Owen F, Seidman J, et al. Identification of a putative second T-cell receptor. Nature 1986;322:145-149.
2. Alexandre D, Lefranc MP. The human gamma/delta+ and alpha/ beta+ T cells: a branched pathway of differentiation. Mol Immunol 1992;29:447-451.
3. Beldjord K, Beldjord C, Macintyre E, Even P, Sigaux F. Peripheral selection of V delta 1+ cells with restricted T cell receptor delta gene junctional repertoire in the peripheral blood of healthy donors. J Exp Med 1993;178:121-127.
4. Bonneville M, Ito K, Krecko EG, Itohara S, Kappes D, Ishida I, Kanagawa O, et al. Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors. Proc Natl Acad Sci U S A 1989;86:5928-5932.
5. Haas W, Pereira P, Tonegawa S. Gamma/delta cells. Annu Rev Immunol 1993;11:637-685.
6. Bluestone JA, Cron RQ, Cotterman M, Houlden BA, Matis LA. Structure and specificity of T cell receptor gamma/delta on major histocompatibility complex antigen-specific CD3+, CD4-, CDS- T lymphocytes. J Exp Med 1988;168:1899-1916.
7. Porcelli S, Brenner MB, Greenstein JL, Balk SP, Terhorst C, Bleicher PA. Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes. Nature 1989;341: 447-450.
8. Vidovic D, Roglic M, McKune K, Guerder S, MacKay C, Dembic Z. Qa-1 restricted recognition of foreign antigen by a gamma delta T-cell hybridoma. Nature 1989;340:646-650.
9. Faure F, Jitsukawa S, Miossec C, Hercend T. CD1c as a target recognition structure for human T lymphocytes: analysis with peripheral blood gamma/delta cells. Eur J Immunol 1990;20: 703-706.
10. Strominger J. The γδ T cell receptor and class Ib MHC-related proteins: enigmatic molecules of immune recognition. Cell 1989; 57:895-898.
11. Ito K, Van-Kaer L, Bonneville M, Hsu S, Murphy DB, Tonegawa S. Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor. Cell 1990;62:549-561.
12. Keystone E, Rittershaus C, Wood N, Snow K, Flatow J, Purvis J. Elevation of a γδ T cell subset in peripheral blood and synovial fluid of patients with rheumatoid arthritis. Clin Exp Immunol 1991;84:78-82.
13. Olive C, Gatenby PA, Serjeantson SW. Variable gene usage of T cell receptor gamma- and delta-chain transcripts expressed in synovia and peripheral blood of patients with rheumatoid arthritis. Clin Exp Immunol 1992;87:172-177.
14. Bucht A, Soderstrom K, Hultman T, Uhlen M, Nilsson E, Kiessling R, Gronberg A. T cell receptor diversity and activation markers in the V delta 1 subset of rheumatoid synovial fluid and peripheral blood T lymphocytes. Eur J Immunol 1992;22: 567-574.
15. Savilahti E, Arato A, Verkasalo M. Intestinal gamma/delta receptor-bearing T lymphocytes in celiac disease and inflammatory bowel diseases in children: constant increase in celiac disease. Pediatr Res 1990;28:579-581.
16. Shimonkevitz R, Colburn C, Burnham JA, Murray RS, Kotzin BL. Clonal expansions of activated gamma/delta T cells in recent-onset multiple sclerosis. Proc Natl Acad Sci U S A 1993;90: 923-927.
17. Morio T, Nagasawa M, Nonoyama S, Okawa H, Yata J. Phenotypic profile and functions of T cell receptor-gamma delta-bearing cells from patients with primary immunodeficiency syndrome. J Immunol 1990;144:1270-1275.
18. Carbonari M, Cherchi M, Paganelli R, Giannini G, Galli E, Gaetano C, Papetti C, et al. Relative increase of T cells expressing the gamma/delta rather than the alpha/beta receptor in ataxia-telangiectasia. N Engl J Med 1990;322:73-76.
19. Kabelitz D, Bender A, Schondelmaier S, da-Silva-Lobo ML, Janssen O. Human cytotoxic lymphocytes. V. Frequency and specificity of gamma delta+ cytotoxic lymphocyte precursors activated by allogeneic or autologous stimulator cells. J Immunol 1990; 145:2827-2832.
20. Chapman RWG, Arborgh BÅM, Rhodes JM, Summerfield JA, Dick R, Scheuer PJ, Sherlock S. Primary sclerosing cholangitis: a review of its clinical features, cholangiography, and hepatic histology. Gut 1980;21:870-877.
21. LaRusso NF, Wiesner RH, Ludwig J, MacCarty RJ. Primary sclerosing cholangitis. N Engl J Med 1984;310:899-903.
22. Wiesner RH, LaRusso NF. Clinicopathologic features of the syndrome of primary sclerosing cholangitis. Gastroenterology 1980; 79:200-206.
23. Lo SK, Chapman RW, Cheeseman P, Charlton CP, Walker-Smith JA, Mieli-Vergani G, Fleming KA. Antineutrophil antibody: a test for autoimmune primary sclerosing cholangitis in childhood? Gut 1993;34:199-202.
24. Lo SK, Fleming KA, Chapman RW. Prevalence of anti-neutrophil antibody in primary sclerosing cholangitis and ulcerative colitis using an alkaline phosphatase technique. Gut 1992;33:1370-1375.