Analysis of the phenotype and cytokine pattern of blood- and skin-derived nickel specific T cells in allergic contact dermatitis

International Archives of Allergy and Immunology

Volumn 113, Issue 1-3, 1997, Pages 384-386

  Werfel, Thomas ^a   Hentschel, Michael ^a   Renz, Harald ^b   Kapp, Alexander ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Allergic contact dermatitis; Eczema; Interleukin 4; Nickel sulfate; T lymphocytes

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4; NICKEL;

CASE REPORT; CONFERENCE PAPER; CONTACT SENSITIVITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; SKIN ALLERGY; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

DERMATITIS, ALLERGIC CONTACT; HUMANS; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-4; NICKEL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES;

EID: 0030889886     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237610     Document Type: Article

References (6)

1. Kapsenbcrg MI, Wiercnga EA, Stickcma EM, Tiggelmann AM, Bos JD: Tli I lymphokinc production profiles of nickel specific CD4+T-lym-phocyte clones from nickel contact allergic and non-allergic individuals. J Invest Dermatol 1992:98:59-63.
2. Sager N, Feldniann A, Schilling G, Kreitsch I’, Neumann C: House dust mite-specific T cells in the skin of subjects with atopic dermatitis: Frequency and lymphokinc profile in the allergen patch test, J Allergy Clin Immunol 1992:89: 801-810.
3. Werfel T, Morita A, Grewe M, Renz H, Wahn U, Krutmann J, Kapp A: Allergen specificity of skin-infiltrating T cells is not restricted to a typc-2 cytokine pattern in chronic skin lesions of atopic dermatitis. J Invest Dermatol 1996; 107:871-876.
4. Hamid Q, Boguniewicz M, Leung DYM: Differential cytokine gene expression in acute vs chronic atopic dermatitis. J Clin Invest 1994; 94:870-876.
5. Grcwc M, Gyufko K, Scliòpf E, Krutmann J: Lesionai expression of interferon-γ in atopic eczema. Lancet 1994:343:25-26.
6. Ohmen JD, Hanifin JM, Nickoloff BJ, Rea TH, Wyzykowski R, Kim J, Jullien D, McHugh T, Nassif AS, Chan SC, Modlin RL: Ovcrcxpres-sion of IL-10 in atopic dermatitis. Contrasting cytokine patterns with delaycd-type hypersensitivity reactions. J Immunol 1995:154:1956-1963.