Generation of single-domain antibody multimers with three different self-associating peptides

Protein Engineering, Design and Selection

Volumn 26, Issue 6, 2013, Pages 417-423

  Wang, Lifei ^a,b   Liu, Xiaoli ^c   Zhu, Xuekai ^a,d   Wang, Lei ^a,d   Wang, Wei ^a,b   Liu, Changzhen ^a   Cui, Honglian ^a   Sun, Meiyi ^c   Gao, Bin ^a,b  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c Epigen Biotech   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

antibody multimerization; C4 binding protein chain c terminal; human cartilage oligomeric matrix protein; right handed coiled coil; single domain antibody

Indexed keywords

BINDING PROTEINS; COILED COIL; MATRIX PROTEINS; MULTIMERIZATION; SINGLE-DOMAIN ANTIBODIES;

AFFINITY CHROMATOGRAPHY; CARTILAGE; OLIGOMERS; PEPTIDES;

ANTIBODIES;

CARTILAGE OLIGOMERIC MATRIX PROTEIN; COMPLEMENT COMPONENT C4 BINDING PROTEIN; COMPLEMENT COMPONENT C4 BINDING PROTEIN ALPHA CHAIN; CYTOPLASM PROTEIN; NANOBODY; PENTAMER; PEPTIDE; POLYMER; RHCC PEPTIDE; TETRAMER; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING KINETICS; CONTROLLED STUDY; HEPTAMER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION;

ANTIBODY MULTIMERIZATION; C4-BINDING PROTEIN Α-CHAIN C-TERMINAL; HUMAN CARTILAGE OLIGOMERIC MATRIX PROTEIN; RIGHT-HANDED COILED COIL; SINGLE-DOMAIN ANTIBODY;

ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLOW CYTOMETRY; HUMANS; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SINGLE-DOMAIN ANTIBODIES; SURFACE PLASMON RESONANCE;

EID: 84878064447     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzt011     Document Type: Article

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