메뉴 건너뛰기




Volumn 21, Issue 22, 2002, Pages 5960-5968

Storage function of cartilage oligomeric matrix protein: The crystal structure of the coiled-coil domain in complex with vitamin D3

Author keywords

Hydrophobic pore; Vitamin D3 storage; X ray crystallography

Indexed keywords

CARTILAGE OLIGOMERIC MATRIX PROTEIN; COLECALCIFEROL; RETINOIC ACID;

EID: 0037112753     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf628     Document Type: Article
Times cited : (57)

References (53)
  • 1
    • 0035178990 scopus 로고    scopus 로고
    • Thrombospondins: Multifunctional regulators of cell interactions
    • Adams, J.C. (2001) Thrombospondins: Multifunctional regulators of cell interactions. Annu. Rev. Cell Dev. Biol., 17, 25-51.
    • (2001) Annu. Rev. Cell Dev. Biol. , vol.17 , pp. 25-51
    • Adams, J.C.1
  • 2
    • 0034043855 scopus 로고    scopus 로고
    • Annexin II is the membrane receptor that mediates the rapid actions of 1α,25-dihydroxyvitamin D(3)
    • Baran, D.T., Quail, J.M., Ray, R., Leszyk, J. and Honeyman, T. (2000) Annexin II is the membrane receptor that mediates the rapid actions of 1α,25-dihydroxyvitamin D(3). J. Cell. Biochem., 78, 34-46.
    • (2000) J. Cell. Biochem. , vol.78 , pp. 34-46
    • Baran, D.T.1    Quail, J.M.2    Ray, R.3    Leszyk, J.4    Honeyman, T.5
  • 3
    • 0035875881 scopus 로고    scopus 로고
    • A Phase I trial of pulse calcitriol in patients with refractory malignancies
    • Beer, T.M., Munar, M. and Henner, W.D. (2001) A Phase I trial of pulse calcitriol in patients with refractory malignancies. Cancer, 91, 2431-2439.
    • (2001) Cancer , vol.91 , pp. 2431-2439
    • Beer, T.M.1    Munar, M.2    Henner, W.D.3
  • 4
  • 5
    • 0028988403 scopus 로고
    • Structure-function relationships in the vitamin D endocrine system
    • Bouillon, R., Okamura, W.H. and Norman, A.W. (1995) Structure- function relationships in the vitamin D endocrine system. Endocr. Rev., 16, 200-257.
    • (1995) Endocr. Rev. , vol.16 , pp. 200-257
    • Bouillon, R.1    Okamura, W.H.2    Norman, A.W.3
  • 6
    • 17344374325 scopus 로고    scopus 로고
    • Diverse mutations in the gene for cartilage oligomeric matrix protein in the pseudoachondroplasia-multiple epiphyseal dysplasia disease spectrum
    • Briggs, M.D. et al. (1998) Diverse mutations in the gene for cartilage oligomeric matrix protein in the pseudoachondroplasia-multiple epiphyseal dysplasia disease spectrum. Am. J. Hum. Genet., 62, 311-319.
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 311-319
    • Briggs, M.D.1
  • 7
    • 3543012707 scopus 로고    scopus 로고
    • Crystallography & NMR system: A new software suite for macromolecular structure determination
    • Brunger, A.T. et al. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination., Acta Crystallogr. D, 54, 905-921.
    • (1998) Acta Crystallogr. D , vol.54 , pp. 905-921
    • Brunger, A.T.1
  • 8
    • 0028103275 scopus 로고
    • The CCP4 suite: Programs for protein crystallography
    • CCP4 (1994) The CCP4 suite: Programs for protein crystallography. Acta Crystallogr. D, 50, 760-763.
    • (1994) Acta Crystallogr. D , vol.50 , pp. 760-763
  • 9
    • 0027310780 scopus 로고
    • Crystallographic studies on a family of cellular lipophilic transport proteins. Refinement of P2 myelin protein and the structure determination and refinement of cellular retinol-binding protein in complex with alltrans-retinol
    • Cowan, S.W., Newcomer, M.E. and Jones, T.A. (1993) Crystallographic studies on a family of cellular lipophilic transport proteins. Refinement of P2 myelin protein and the structure determination and refinement of cellular retinol-binding protein in complex with alltrans-retinol. J. Mol. Biol., 230, 1225-1246.
    • (1993) J. Mol. Biol. , vol.230 , pp. 1225-1246
    • Cowan, S.W.1    Newcomer, M.E.2    Jones, T.A.3
  • 10
    • 0028090357 scopus 로고
    • Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon
    • DiCesare, P., Hauser, N., Lehman, D., Pasumarti, S. and Paulsson, M. (1994) Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon. FEBS Lett., 354, 237-240.
    • (1994) FEBS Lett. , vol.354 , pp. 237-240
    • DiCesare, P.1    Hauser, N.2    Lehman, D.3    Pasumarti, S.4    Paulsson, M.5
  • 11
    • 0028213804 scopus 로고
    • The thrombospondin-like chains of cartilage oligomeric matrix protein are assembled by a five-stranded α-helical bundle between residues 20 and 83
    • Efimov, V.P., Lustig, A. and Engel, J. (1994) The thrombospondin-like chains of cartilage oligomeric matrix protein are assembled by a five-stranded α-helical bundle between residues 20 and 83. FEBS Lett., 341, 54-58.
    • (1994) FEBS Lett. , vol.341 , pp. 54-58
    • Efimov, V.P.1    Lustig, A.2    Engel, J.3
  • 12
    • 0029868783 scopus 로고    scopus 로고
    • Crystallization and preliminary crystallographic study of the pentamerizing domain from cartilage oligomeric matrix protein: A five-stranded α-helical bundle
    • Efimov, V.P., Engel, J. and Malashkevich, V.N. (1996) Crystallization and preliminary crystallographic study of the pentamerizing domain from cartilage oligomeric matrix protein: A five-stranded α-helical bundle. Proteins, 24, 259-262.
    • (1996) Proteins , vol.24 , pp. 259-262
    • Efimov, V.P.1    Engel, J.2    Malashkevich, V.N.3
  • 13
    • 0031008279 scopus 로고    scopus 로고
    • Ultrastructural immunolocalization of cartilage oligomeric matrix protein (COMP) in porcine growth cartilage
    • Ekman, S., Reinholt, F.P., Hultenby, K. and Heinegard, D. (1997) Ultrastructural immunolocalization of cartilage oligomeric matrix protein (COMP) in porcine growth cartilage. Calcif. Tissue Int., 60, 547-553.
    • (1997) Calcif. Tissue Int. , vol.60 , pp. 547-553
    • Ekman, S.1    Reinholt, F.P.2    Hultenby, K.3    Heinegard, D.4
  • 14
    • 0031862952 scopus 로고    scopus 로고
    • Ascorbic acid-induced chondrocyte terminal differentiation: The role of the extracellular matrix and 1,25-dihydroxyvitamin D
    • Farquharson, C., Berry, J.L., Mawer, E.B., Seawright, E. and Whitehead, C.C. (1998) Ascorbic acid-induced chondrocyte terminal differentiation: The role of the extracellular matrix and 1,25-dihydroxyvitamin D. Eur. J. Cell Biol., 76, 110-118.
    • (1998) Eur. J. Cell Biol. , vol.76 , pp. 110-118
    • Farquharson, C.1    Berry, J.L.2    Mawer, E.B.3    Seawright, E.4    Whitehead, C.C.5
  • 15
    • 0034077195 scopus 로고    scopus 로고
    • 24,25-Dihydroxyvitamin D3 in combination with 1,25-dihydroxyvitamin D3 ameliorates renal osteodystrophy in rats with chronic renal failure
    • Gal-Moscovici, A., Rubinger, D. and Popovtzer, M.M. (2000) 24,25-Dihydroxyvitamin D3 in combination with 1,25-dihydroxyvitamin D3 ameliorates renal osteodystrophy in rats with chronic renal failure. Clin. Nephrol., 53, 362-371.
    • (2000) Clin. Nephrol. , vol.53 , pp. 362-371
    • Gal-Moscovici, A.1    Rubinger, D.2    Popovtzer, M.M.3
  • 16
    • 0032530389 scopus 로고    scopus 로고
    • All-trans retinol, vitamin D and other hydrophobic compounds bind in the axial pore of the five-stranded coiled-coil domain of cartilage oligomeric matrix protein
    • Guo, Y., Bozic, D., Malashkevich, V.N., Kammerer, R.A., Schulthess, T. and Engel, J. (1998) All-trans retinol, vitamin D and other hydrophobic compounds bind in the axial pore of the five-stranded coiled-coil domain of cartilage oligomeric matrix protein. EMBO J., 17, 5265-5272.
    • (1998) EMBO J. , vol.17 , pp. 5265-5272
    • Guo, Y.1    Bozic, D.2    Malashkevich, V.N.3    Kammerer, R.A.4    Schulthess, T.5    Engel, J.6
  • 17
    • 0035061146 scopus 로고    scopus 로고
    • Oral administration of 1-α-hydroxy-vitamin D3 inhibits tumor growth and metastasis of a murine osteosarcoma model
    • Hara, K., Kusuzaki, K., Takeshita, H., Kuzuhara, A., Tsuji, Y., Ashihara, T. and Hirasawa, Y. (2001) Oral administration of 1-α-hydroxy-vitamin D3 inhibits tumor growth and metastasis of a murine osteosarcoma model. Anticancer Res., 21, 321-324.
    • (2001) Anticancer Res. , vol.21 , pp. 321-324
    • Hara, K.1    Kusuzaki, K.2    Takeshita, H.3    Kuzuhara, A.4    Tsuji, Y.5    Ashihara, T.6    Hirasawa, Y.7
  • 19
    • 0037162424 scopus 로고    scopus 로고
    • Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 Å resolution
    • Head, J.F., Swamy, N. and Ray, R. (2002) Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 Å resolution. Biochemistry, 41, 9015-9020.
    • (2002) Biochemistry , vol.41 , pp. 9015-9020
    • Head, J.F.1    Swamy, N.2    Ray, R.3
  • 20
    • 0029035708 scopus 로고
    • Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia
    • Hecht, J.T. et al. (1995) Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia. Nat. Genet., 10, 325-329.
    • (1995) Nat. Genet. , vol.10 , pp. 325-329
    • Hecht, J.T.1
  • 21
    • 0032432979 scopus 로고    scopus 로고
    • Retention of cartilage oligomeric matrix protein (COMP) and cell death in redifferentiated pseudoachondroplasia chondrocytes
    • Hecht, J.T., Montufar-Solis, D., Decker, G., Lawler, J., Daniels, K. and Duke, P.J. (1998) Retention of cartilage oligomeric matrix protein (COMP) and cell death in redifferentiated pseudoachondroplasia chondrocytes. Matrix Biol., 17, 625-633.
    • (1998) Matrix Biol. , vol.17 , pp. 625-633
    • Hecht, J.T.1    Montufar-Solis, D.2    Decker, G.3    Lawler, J.4    Daniels, K.5    Duke, P.J.6
  • 22
    • 0026671581 scopus 로고
    • Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage
    • Hedbom, E. et al. (1992) Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage. J. Biol. Chem., 267, 6132-6136.
    • (1992) J. Biol. Chem. , vol.267 , pp. 6132-6136
    • Hedbom, E.1
  • 23
    • 0035110374 scopus 로고    scopus 로고
    • Comparative safety of bone remodeling agents with a focus on osteoporosis therapies
    • Kleerekoper, M. and Schein, J.R. (2001) Comparative safety of bone remodeling agents with a focus on osteoporosis therapies. J. Clin. Pharmacol., 41, 239-250.
    • (2001) J. Clin. Pharmacol. , vol.41 , pp. 239-250
    • Kleerekoper, M.1    Schein, J.R.2
  • 26
    • 0029911261 scopus 로고    scopus 로고
    • The crystal structure of a five-stranded coiled coil in COMP: A prototype ion channel?
    • Malashkevich, V.N., Kammerer, R.A., Efimov, V.P., Schulthess, T. and Engel, J. (1996) The crystal structure of a five-stranded coiled coil in COMP: A prototype ion channel? Science, 274, 761-765.
    • (1996) Science , vol.274 , pp. 761-765
    • Malashkevich, V.N.1    Kammerer, R.A.2    Efimov, V.P.3    Schulthess, T.4    Engel, J.5
  • 27
    • 0032780531 scopus 로고    scopus 로고
    • The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets
    • Malloy, P.J., Pike, J.W. and Feldman, D. (1999) The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets. Endocr. Rev., 20, 156-188.
    • (1999) Endocr. Rev. , vol.20 , pp. 156-188
    • Malloy, P.J.1    Pike, J.W.2    Feldman, D.3
  • 28
    • 0026703257 scopus 로고
    • Electron microscopy of native cartilage oligomeric matrix protein purified from the Swarm rat chondrosarcoma reveals a five-armed structure
    • Mörgelin, M., Heinegard, D., Engel, J. and Paulsson, M. (1992) Electron microscopy of native cartilage oligomeric matrix protein purified from the Swarm rat chondrosarcoma reveals a five-armed structure. J. Biol. Chem., 267, 6137-6141.
    • (1992) J. Biol. Chem. , vol.267 , pp. 6137-6141
    • Mörgelin, M.1    Heinegard, D.2    Engel, J.3    Paulsson, M.4
  • 29
    • 0032456952 scopus 로고    scopus 로고
    • COMP (cartilage oligomeric matrix protein) is synthesized in ligament, tendon, meniscus, and articular cartilage
    • Müller, G., Michel, A. and Altenburg, E. (1998) COMP (cartilage oligomeric matrix protein) is synthesized in ligament, tendon, meniscus, and articular cartilage. Connect. Tissue Res., 39, 233-244.
    • (1998) Connect. Tissue Res. , vol.39 , pp. 233-244
    • Müller, G.1    Michel, A.2    Altenburg, E.3
  • 32
    • 0013925343 scopus 로고
    • 3 and tissue localization of a 0.25-μg (10 IU) dose per rat
    • 3 and tissue localization of a 0.25-μg (10 IU) dose per rat. Biochemistry, 5, 2201-2207.
    • (1966) Biochemistry , vol.5 , pp. 2201-2207
    • Neville, P.F.1    DeLuca, H.F.2
  • 33
    • 0034987088 scopus 로고    scopus 로고
    • Ligands for the vitamin D endocrine system: Different shapes function as agonists and antagonists for genomic and rapid response receptors or as a ligand for the plasma vitamin D binding protein
    • Norman, A.W., Ishizuka, S. and Okamura, W.H. (2001) Ligands for the vitamin D endocrine system: Different shapes function as agonists and antagonists for genomic and rapid response receptors or as a ligand for the plasma vitamin D binding protein. J. Steroid Biochem. Mol. Biol., 76, 49-59.
    • (2001) J. Steroid Biochem. Mol. Biol. , vol.76 , pp. 49-59
    • Norman, A.W.1    Ishizuka, S.2    Okamura, W.H.3
  • 36
    • 0026499722 scopus 로고
    • COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins
    • Oldberg, A., Antonsson, P., Lindblom, K. and Heinegard, D. (1992) COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins. J. Biol. Chem., 267, 22346-22350.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22346-22350
    • Oldberg, A.1    Antonsson, P.2    Lindblom, K.3    Heinegard, D.4
  • 37
    • 0026444078 scopus 로고
    • Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers
    • O'Rourke, K.M., Laherty, C.D. and Dixit, V.M. (1992) Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers. J. Biol. Chem., 267, 24921-24924.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24921-24924
    • O'Rourke, K.M.1    Laherty, C.D.2    Dixit, V.M.3
  • 38
    • 0029070839 scopus 로고
    • Thrombospondin 3 is a pentameric molecule held together by interchain disulfide linkage involving two cysteine residues
    • Qabar, A., Derick, L., Lawler, J. and Dixit, V. (1995) Thrombospondin 3 is a pentameric molecule held together by interchain disulfide linkage involving two cysteine residues. J. Biol. Chem., 270, 12725-12729.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12725-12729
    • Qabar, A.1    Derick, L.2    Lawler, J.3    Dixit, V.4
  • 39
    • 0029799260 scopus 로고    scopus 로고
    • Molecular recognition in vitamin D-binding protein
    • Ray, R. (1996) Molecular recognition in vitamin D-binding protein. Proc. Soc. Exp. Biol. Med., 212, 305-312.
    • (1996) Proc. Soc. Exp. Biol. Med. , vol.212 , pp. 305-312
    • Ray, R.1
  • 40
    • 0033963897 scopus 로고    scopus 로고
    • The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand
    • Rochel, N., Wurtz, J.M., Mitschler, A., Klaholz, B. and Moras, D. (2000) The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand. Mol. Cell, 5, 173-179.
    • (2000) Mol. Cell , vol.5 , pp. 173-179
    • Rochel, N.1    Wurtz, J.M.2    Mitschler, A.3    Klaholz, B.4    Moras, D.5
  • 41
    • 0032977457 scopus 로고    scopus 로고
    • Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane
    • Rosner, W., Hryb, D.J., Khan, M.S., Nakhla, A.M. and Romas, N.A. (1999) Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane. J. Steroid Biochem. Mol. Biol., 69, 481-485.
    • (1999) J. Steroid Biochem. Mol. Biol. , vol.69 , pp. 481-485
    • Rosner, W.1    Hryb, D.J.2    Khan, M.S.3    Nakhla, A.M.4    Romas, N.A.5
  • 42
    • 0030040323 scopus 로고    scopus 로고
    • Reduced surface: An efficient way to compute molecular surfaces
    • Sanner, M.F., Olson, A.J. and Spehner, J.C. (1996) Reduced surface: An efficient way to compute molecular surfaces. Biopolymers, 38, 305-320.
    • (1996) Biopolymers , vol.38 , pp. 305-320
    • Sanner, M.F.1    Olson, A.J.2    Spehner, J.C.3
  • 43
    • 0029582845 scopus 로고
    • Distribution and expression of cartilage oligomeric matrix protein and bone sialoprotein show marked changes during rat femoral head development
    • Shen, Z., Heinegard, D. and Sommarin, Y. (1995) Distribution and expression of cartilage oligomeric matrix protein and bone sialoprotein show marked changes during rat femoral head development. Matrix Biol., 14, 773-781.
    • (1995) Matrix Biol. , vol.14 , pp. 773-781
    • Shen, Z.1    Heinegard, D.2    Sommarin, Y.3
  • 44
    • 0031282595 scopus 로고    scopus 로고
    • The distribution of cartilage oligomeric matrix protein (COMP) in tendon and its variation with tendon site, age and load
    • Smith, R.K., Zunino, L., Webbon, P.M. and Heinegard, D. (1997) The distribution of cartilage oligomeric matrix protein (COMP) in tendon and its variation with tendon site, age and load. Matrix Biol., 16, 255-271.
    • (1997) Matrix Biol. , vol.16 , pp. 255-271
    • Smith, R.K.1    Zunino, L.2    Webbon, P.M.3    Heinegard, D.4
  • 45
    • 0040514620 scopus 로고    scopus 로고
    • Crystal and molecular structure of 1,25-dihydroxycholecalciferol
    • Suwinska, K. and Kutner, A. (1996) Crystal and molecular structure of 1,25-dihydroxycholecalciferol. Acta Crystallogr. B, 52, 550-554.
    • (1996) Acta Crystallogr. B , vol.52 , pp. 550-554
    • Suwinska, K.1    Kutner, A.2
  • 47
    • 0035794206 scopus 로고    scopus 로고
    • Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX
    • Thur, J., Rosenberg, K., Nitsche, D.P., Pihlajamaa, T., Ala-Kokko, L., Heinegard, D., Paulsson, M. and Maurer, P. (2001) Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX. J. Biol. Chem., 276, 6083-6092.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6083-6092
    • Thur, J.1    Rosenberg, K.2    Nitsche, D.P.3    Pihlajamaa, T.4    Ala-Kokko, L.5    Heinegard, D.6    Paulsson, M.7    Maurer, P.8
  • 52
    • 0027050850 scopus 로고
    • Newly identified actions of the vitamin D endocrine system
    • Walters, M.R. (1992) Newly identified actions of the vitamin D endocrine system. Endocr. Rev., 13, 719-764.
    • (1992) Endocr. Rev. , vol.13 , pp. 719-764
    • Walters, M.R.1
  • 53
    • 0035985694 scopus 로고    scopus 로고
    • Pathways for kidney-specific uptake of the steroid hormone 25-hydroxyvitamin D3
    • Willnow, T.E. and Nykjaer, A. (2002) Pathways for kidney-specific uptake of the steroid hormone 25-hydroxyvitamin D3. Curr. Opin. Lipidol., 13, 255-260.
    • (2002) Curr. Opin. Lipidol. , vol.13 , pp. 255-260
    • Willnow, T.E.1    Nykjaer, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.