Combined Na+/Ca2+ exchanger and l-type calcium channel block as a potential strategy to suppress arrhythmias and maintain ventricular function

Circulation: Arrhythmia and Electrophysiology

Volumn 6, Issue 2, 2013, Pages 371-379

  Bourgonje, Vincent J A ^a   Vos, Marc A ^a   Ozdemir, Semir ^b,d   Doisne, Nicolas ^b   Acsai, Karoly ^e   Varro, Andras ^e   Sztojkov Ivanov, Anita ^e   Zupko, Istvan ^e   Rauch, Erik ^f   Kattner, Lars ^f   Bito, Virginie ^b   Houtman, Marien ^a   Van Der Nagel, Roel ^a   Beekman, Jet D ^a   Van Veen, Toon A B ^a   Sipido, Karin R ^b   Antoons, Gudrun ^b,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

^d AKDENIZ UNIVERSITY   (Turkey)

^e UNIVERSITY OF SZEGED   (Hungary)

^f Endotherm Life Science Molecules   (Germany)

Author keywords

Antiarrhythmic drug; Calcium channel; Heart failure; Long QT syndrome; Na + Ca2+ exchange; Torsade de Pointes

Indexed keywords

2 [4 (2,5 DIFLUOROBENZYLOXY)PHENOXY] 5 ETHOXYANILINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; DOFETILIDE; SODIUM CALCIUM EXCHANGE PROTEIN; VERAPAMIL;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATRIOVENTRICULAR BLOCK; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; DRUG EFFECT; ELECTROCARDIOGRAM; EXPERIMENTAL DOG; HEART ARRHYTHMIA; HEART DEPOLARIZATION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; HEART PROARRHYTHMIA; HEART RATE; HEART REPOLARIZATION; HEART VENTRICLE FUNCTION; HEMODYNAMICS; LOW DRUG DOSE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; SARCOPLASMIC RETICULUM; TORSADE DES POINTES;

ACTION POTENTIALS; ANILINE COMPOUNDS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; CALCIUM CHANNELS, L-TYPE; DISEASE MODELS, ANIMAL; DOGS; ELECTROCARDIOGRAPHY; HEART VENTRICLES; MYOCYTES, CARDIAC; PHENYL ETHERS; SODIUM-CALCIUM EXCHANGER; VENTRICULAR FUNCTION; VENTRICULAR PRESSURE;

EID: 84878025942     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/CIRCEP.113.000322     Document Type: Article

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