Protective effects of SEA0400, a novel and selective inhibitor of the Na+/Ca2+ exchanger, on myocardial ischemia-reperfusion injuries

European Journal of Pharmacology

Volumn 458, Issue 1-2, 2003, Pages 155-162

  Takahashi, Kenzo ^a   Takahashi, Teisuke ^a   Suzuki, Taizo ^a   Onishi, Michihito ^a   Tanaka, Yu ^a   Hamano Takahashi, Akiko ^a   Ota, Tomomi ^a   Kameo, Kazuya ^a   Matsuda, Toshio ^b   Baba, Akemichi ^b  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Inhibitor; Ischemia; Myocardial injury; Na+ Ca2+ exchanger; Reperfusion; SEA0400

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; 2 [4 (2,5 DIFLUOROBENZYLOXY)PHENOXY] 5 ETHOXYANILINE; 2 [4 [(2,5 DIFLUOROPHENYL)METHOXY]PHENOXYL] 5 ETHOXYANILINE; CALCIUM ION; PROTEIN INHIBITOR; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL DEATH; CONTROLLED STUDY; DOG; DRUG EFFECT; DRUG POTENCY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART VENTRICLE FIBRILLATION; IC 50; ISOLATED HEART; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MORTALITY; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SARCOLEMMA;

ANILINE COMPOUNDS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIA; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; DOGS; GUANIDINES; HEART; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; PHENYL ETHERS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SARCOLEMMA; SODIUM-CALCIUM EXCHANGER; SULFONES; THIOUREA;

EID: 12244310476     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02732-2     Document Type: Article

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